Compounds > brusatol
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brusatol and Carcinoma, Non-Small Cell Lung

brusatol has been researched along with Carcinoma, Non-Small Cell Lung in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Chen, YF; He, DH; Huang, D; Huang, H; Liu, YQ; Nong, F; Qin, J; Wang, Y; Wu, PE; Xing, S; Xu, H; Zhan, R1
Du, L; Hao, J; Ji, K; Kong, Y; Li, N; Liu, Q; Liu, Y; Nie, S; Sun, X; Wang, Y; Xie, Y; Xu, C1
Chen, J; Ip, S; Lai, Z; Li, Q; Liao, H; Lin, Z; Su, Z; Wu, J; Xian, Y; Xie, J; Xie, Y; Yang, X; Zheng, X1
Chapman, E; Moghaddam, SJ; Ooi, A; Tao, S; Wang, S; Wong, PK; Zhang, DD1
Haverty, PM; Kirkpatrick, DS; Lee, J; Ma, TP; Stokoe, D; Vartanian, S; Yu, K1

Other Studies

5 other study(ies) available for brusatol and Carcinoma, Non-Small Cell Lung

ArticleYear
Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis.
    Pharmacological research, 2022, Volume: 176

    Topics: Animals; Antineoplastic Agents; Biotin; Carcinoma, Non-Small-Cell Lung; Cell Line; Humans; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Quassins; S-Phase Kinase-Associated Proteins

2022
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
    Nucleic acids research, 2020, 09-18, Volume: 48, Issue:16

    Topics: A549 Cells; Animals; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase; Checkpoint Kinase 1; DNA Breaks, Double-Stranded; DNA Damage; G2 Phase Cell Cycle Checkpoints; Gene Knockout Techniques; Heterografts; Humans; Mice; NF-E2-Related Factor 2; Quassins; Radiation Tolerance; Radiation, Ionizing; Recombinational DNA Repair; Signal Transduction

2020
Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response.
    Toxicology, 2021, 03-15, Volume: 451

    Topics: A549 Cells; Antioxidants; Apoptosis; Brucea; Carcinoma, Non-Small-Cell Lung; Cell Survival; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mitochondria; NF-E2-Related Factor 2; Quassins; Reactive Oxygen Species

2021
Oncogenic KRAS confers chemoresistance by upregulating NRF2.
    Cancer research, 2014, Dec-15, Volume: 74, Issue:24

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Resistance; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mice; Mutation; NF-E2-Related Factor 2; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quassins; ras Proteins; Response Elements

2014
Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:4

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Mass Spectrometry; Mutation; NF-E2-Related Factor 2; Protein Synthesis Inhibitors; Proteomics; Quassins

2016