bropirimine has been researched along with Arthritis* in 1 studies
1 other study(ies) available for bropirimine and Arthritis
Article | Year |
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Pyrimidinones. 3. N-substituted 6-phenylpyrimidinones and pyrimidinediones with diuretic/hypotensive and antiinflammatory activity.
In an extensive analysis of the antiviral and interferon-induction structure-activity relationship of 6-arylpyrimidinones we found that modifications at positions 1-4 of the pyrimidine ring resulted in a loss of activity. However, we uncovered interesting hypotensive and antiinflammatory activity with a series of N-substituted analogues, the results of which we report herein. Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Arthritis; Diuresis; Dose-Response Relationship, Drug; Female; Furosemide; Guanethidine; Heart; Hydrochlorothiazide; Hypotension; Male; Methylation; Natriuresis; Phenylacetates; Potassium; Pyrimidinones; Rats; Rats, Inbred Strains; Stilbenes; Structure-Activity Relationship; Tamoxifen | 1986 |