brompheniramine--pseudoephedrine-drug-combination has been researched along with Tooth-Erosion* in 2 studies
2 other study(ies) available for brompheniramine--pseudoephedrine-drug-combination and Tooth-Erosion
| Article | Year |
|---|---|
ATR-FTIR spectroscopy and μ-EDXRF spectrometry monitoring of enamel erosion caused by medicaments used in the treatment of respiratory diseases.
Medicaments essential for alleviation of diseases may sometime adversely affect dental health by eroding the enamel, owing to their acidic nature. It is therefore highly desirable to be able to detect these effects quickly and reliably. In this study, we evaluated the erosive capacity of four most commonly prescribed respiratory disease syrup medicaments on enamel using micro-energy-dispersive X-ray fluorescence spectrometry (µ-EDXRF) and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Fifty-five enamel fragments obtained from 30 bovine teeth were treated with artificial saliva (S), acebrofilin hydrochloride (AC), ambroxol hydrochloride (AM), bromhexine hydrochloride (BR), and salbutamol sulfate (SS); by immersing in 3 mL of respective solutions for 1 min, three times a day at intervals of 1 hr, for 5 days. µ-EDXRF analysis of enamel surface did not reveal significant erosion caused by the medications. However, ATR-FTIR showed a detectable shift in the phosphate (PO Topics: Anti-Allergic Agents; Brompheniramine; Dental Enamel; Drug Combinations; Humans; Loratadine; Microscopy, Electron, Scanning; Molar; Nasal Decongestants; Nonprescription Drugs; Pseudoephedrine; Respiratory Tract Diseases; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tooth Erosion | 2018 |
In vitro alterations in dental enamel exposed to acidic medicines.
To evaluate the effect of acidic medicines (Klaricid(®), Claritin(®), and Dimetapp(®)) on surface enamel in vitro.. Enamel blocks (n=104) were randomly distributed into two groups: G1 (pH-cycling simulating physiological oral conditions) and G2 (erosive conditions). Each group was divided into four subgroups, three to be immersed in the medicines and the control in deionized water. Specimen surfaces were evaluated for roughness and hardness at baseline and again after the in vitro experimental phase, which included 30 min immersions in the medicines twice daily for 12 days. Scanning electron microscopy (SEM) was also performed after the in vitro experimental phase.. All medicines produced a significant reduction in hardness in G1 after 12 days (P<0.05). The three medicines promoted greater roughness after both pH-regimens - G1 and G2 (P<0.01), except for Claritin in G1. Scanning electron microscopy analysis showed erosive patterns in all subgroups. Dimetapp(®) showed the most erosion and Klaricid(®) the least, in both groups.. Dimetapp(®) (lowest pH and viscosity) and deionized water (control) showed the most pronounced erosive patterns. Klaricid(®) (highest pH and viscosity) presented an in vitro protective effect against acid attacks perhaps due to its mineral content and viscosity. Topics: Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Brompheniramine; Calcium; Cattle; Citric Acid; Clarithromycin; Dental Enamel; Drug Combinations; Fluorides; Hardness; Hydrogen-Ion Concentration; Loratadine; Microscopy, Electron, Scanning; Phosphorus; Pseudoephedrine; Random Allocation; Respiratory System Agents; Solutions; Temperature; Time Factors; Tooth Erosion; Viscosity | 2011 |