bromperidol has been researched along with Neuroleptic Malignant Syndrome in 2 studies
bromperidol: bromine-substituted for chlorine in haloperidol; RN given refers to unlabeled parent cpd; structure
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recently, some cases of neuroleptic malignant syndrome (NMS) in demented patients have been reported, because the demented patients, who were administered neuroleptics due to their abnormal behaviors, have increased." | 2.39 | [Clinical study of neuroleptic malignant syndrome in demented patients--examination of our case and reported cases]. ( Kimura, T; Yoshida, H, 1994) |
| "Bromperidol 12 mg was prescribed to treat his symptoms." | 1.31 | [Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies]. ( Iwado, H; Morita, Y; Shinjo, H; Ueki, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, T | 1 |
| Yoshida, H | 1 |
| Ueki, A | 1 |
| Iwado, H | 1 |
| Shinjo, H | 1 |
| Morita, Y | 1 |
1 review available for bromperidol and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[Clinical study of neuroleptic malignant syndrome in demented patients--examination of our case and reported cases].
Topics: Aged; Aged, 80 and over; Dementia; Dementia, Vascular; Female; Haloperidol; Humans; Male; Middle Age | 1994 |
1 other study available for bromperidol and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies].
Topics: Aged; Donepezil; Drug Therapy, Combination; Hallucinations; Haloperidol; Humans; Indans; Lewy Body D | 2001 |