Page last updated: 2024-11-06

bromouracil and Inflammation

bromouracil has been researched along with Inflammation in 2 studies

Bromouracil: 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
5-bromouracil : A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henderson, JP2
Byun, J2
Takeshita, J1
Heinecke, JW2
Williams, MV1
Mueller, DM1
McCormick, ML1

Other Studies

2 other studies available for bromouracil and Inflammation

ArticleYear
Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue.
    The Journal of biological chemistry, 2003, Jun-27, Volume: 278, Issue:26

    Topics: Bromouracil; Gas Chromatography-Mass Spectrometry; HL-60 Cells; Humans; Hydrogen-Ion Concentration;

2003
Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation.
    The Journal of biological chemistry, 2001, Mar-16, Volume: 276, Issue:11

    Topics: Bromine; Bromouracil; Deoxycytidine; DNA Damage; Humans; Hydrogen Peroxide; Hypochlorous Acid; Infla

2001