bromouracil has been researched along with Herpes Zoster in 2 studies
Bromouracil: 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
5-bromouracil : A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.
Herpes Zoster: An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sorivudine was given orally as 40 mg once-daily doses for 10 consecutive days to a total of 19 patients with herpes zoster." | 9.08 | The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster. ( Diasio, RB; Haworth, S; Lee, PC; McCrary, MM; Olsen, SJ; Raymond, R; Tyring, SK; Yan, J, 1997) |
| "Sorivudine was given orally as 40 mg once-daily doses for 10 consecutive days to a total of 19 patients with herpes zoster." | 5.08 | The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster. ( Diasio, RB; Haworth, S; Lee, PC; McCrary, MM; Olsen, SJ; Raymond, R; Tyring, SK; Yan, J, 1997) |
| "A toxicokinetic study was performed using rats to investigate the possible mechanism of 18 acute deaths in Japanese patients with cancer and herpes zoster by interactions of the new oral antiviral drug, sorivudine (SRV), with one of the oral 5-fluorouracil (5-FU) prodrugs within 40 days after approval of the use of SRV." | 3.70 | A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs. ( Kato, A; Ogura, K; Okuda, H; Takubo, H; Watabe, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, J | 1 |
| Tyring, SK | 1 |
| McCrary, MM | 1 |
| Lee, PC | 1 |
| Haworth, S | 1 |
| Raymond, R | 1 |
| Olsen, SJ | 1 |
| Diasio, RB | 1 |
| Okuda, H | 1 |
| Ogura, K | 1 |
| Kato, A | 1 |
| Takubo, H | 1 |
| Watabe, T | 1 |
1 trial available for bromouracil and Herpes Zoster
| Article | Year |
|---|---|
The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analysis of Variance; Antiviral Agents; Arab | 1997 |
1 other study available for bromouracil and Herpes Zoster
| Article | Year |
|---|---|
A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cau | 1998 |