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bromouracil and Colonic Neoplasms

bromouracil has been researched along with Colonic Neoplasms in 4 studies

Bromouracil: 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
5-bromouracil : A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alauddin, MM1
Shahinian, A1
Park, R1
Tohme, M1
Fissekis, JD1
Conti, PS1
Berry, SE1
Garces, C1
Hwang, HS1
Kunugi, K1
Meyers, M1
Davis, TW1
Boothman, DA1
Kinsella, TJ1
Ganes, DA1
Wagner, JG1
Kok, RM1
de Jong, AP1
van Groeningen, CJ1
Peters, GJ1
Lankelma, J1

Other Studies

4 other studies available for bromouracil and Colonic Neoplasms

ArticleYear
Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression.
    Nuclear medicine and biology, 2004, Volume: 31, Issue:4

    Topics: Animals; Arabinofuranosyluracil; Biomarkers, Tumor; Bromouracil; Colonic Neoplasms; Fluorouracil; Ge

2004
The mismatch repair protein, hMLH1, mediates 5-substituted halogenated thymidine analogue cytotoxicity, DNA incorporation, and radiosensitization in human colon cancer cells.
    Cancer research, 1999, Apr-15, Volume: 59, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Bromouracil; Carrier Proteins; Cell Survival; Colonic Neoplasm

1999
Improved high-performance liquid chromatographic assay for the quantification of 5-bromo-2'-deoxyuridine and 5-bromouracil in plasma.
    Journal of chromatography, 1988, Nov-18, Volume: 432

    Topics: Aged; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Human

1988
Highly sensitive determination of 5-fluorouracil in human plasma by capillary gas chromatography and negative ion chemical ionization mass spectrometry.
    Journal of chromatography, 1985, Sep-13, Volume: 343, Issue:1

    Topics: Alkylation; Bromouracil; Colonic Neoplasms; Fluorouracil; Gas Chromatography-Mass Spectrometry; Huma

1985