Compounds > bromopyruvate
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bromopyruvate and Pancreatic Neoplasms

bromopyruvate has been researched along with Pancreatic Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Hu, L; Li, Q; Song, T; Sui, X; Wang, F; Wang, X; Xu, X; Zhang, D1
Buijs, M; Ganapathy-Kanniappan, S; Geschwind, JF; Kwak, BK; Ota, S; Wijlemans, JW1
Bauer, N; Bazhin, AV; Fan, P; Gladkich, J; Gross, W; Haberkorn, U; Herr, I; Isayev, O; Liu, L; Mattern, J; Mollenhauer, M; Nwaeburu, CC; Rausch, V; Rückert, F; Schönsiegel, F; Zach, S; Zhang, Y1
Chapiro, J; Duran, R; Ewald, AJ; Ganapathy-Kanniappan, S; Geschwind, JF; Herman, JM; Lin, M; Luo, W; Moats, CR; Reyes, J; Savic, LJ; Semenza, GL; Sur, S; Thiruganasambandam, SC; Tran, PT; Vogelstein, B1
Bhardwaj, V; Bhushan, A; Lai, JC; Lai, MB; Rizvi, N1
Li, S; Liu, T; Wang, F; Xiao, H; Yu, M; Zhang, D1
Cao, X; Cheng, H; Jia, G; Knopp, MV; Sun, D; Wang, B; Wassenaar, PA; Yang, M; Zhang, T1
Bloomston, M; Cao, X; Cheng, H; Frankel, WL; Hall, NC; Jia, G; Knopp, MV; Koch, RM; Sun, D; Wang, B; Zhang, T1

Other Studies

8 other study(ies) available for bromopyruvate and Pancreatic Neoplasms

ArticleYear
The Warburg effect drives cachectic states in patients with pancreatobiliary adenocarcinoma.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:9

    Topics: Adenocarcinoma; Animals; Cachexia; Emodin; Mice; Mice, Nude; Pancreatic Neoplasms

2023
Ultrasound-guided direct delivery of 3-bromopyruvate blocks tumor progression in an orthotopic mouse model of human pancreatic cancer.
    Targeted oncology, 2013, Volume: 8, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Line, Tumor; Female; Humans; Ki-67 Antigen; Lactic Acid; Mice; Mice, Nude; Pancreatic Neoplasms; Pyruvates; Random Allocation; Ultrasonography, Interventional; Xenograft Model Antitumor Assays

2013
Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.
    Oncotarget, 2014, Jul-15, Volume: 5, Issue:13

    Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Survival; Chick Embryo; Deoxycytidine; Female; Gemcitabine; Glucose; Glycolysis; Humans; Immunohistochemistry; Isoenzymes; L-Lactate Dehydrogenase; Mice, Inbred Strains; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; Pyruvates; RNA Interference; Tumor Burden; Xenograft Model Antitumor Assays

2014
Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Dec-15, Volume: 20, Issue:24

    Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Humans; Male; Mice; Pancreatic Neoplasms; Pyruvates; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
Glycolytic enzyme inhibitors affect pancreatic cancer survival by modulating its signaling and energetics.
    Anticancer research, 2010, Volume: 30, Issue:3

    Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hexokinase; Humans; Intracellular Signaling Peptides and Proteins; Iodoacetates; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvates; ras Proteins; Signal Transduction; TOR Serine-Threonine Kinases

2010
Separate and concurrent use of 2-deoxy-D-glucose and 3-bromopyruvate in pancreatic cancer cells.
    Oncology reports, 2013, Volume: 29, Issue:1

    Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Hypoxia; Cell Proliferation; Deoxyglucose; Drug Synergism; Enzyme Inhibitors; Fumarates; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitochondria; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Pyruvate Dehydrogenase Complex; Pyruvates; RNA, Small Interfering; Superoxide Dismutase; Tumor Cells, Cultured

2013
Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6

    Topics: Animals; Antigens, Polyomavirus Transforming; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Glycolysis; Hexokinase; HSP90 Heat-Shock Proteins; Humans; Insulin; Lactams, Macrocyclic; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Neoplasm Proteins; Neovascularization, Pathologic; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyruvates; Rats; Vascular Endothelial Growth Factor A

2008
Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-15, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Hypoxia; Drug Delivery Systems; Drug Synergism; Female; Glycolysis; Hexokinase; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice; Mice, Nude; Pancreatic Neoplasms; Pyruvates; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2008