Page last updated: 2024-08-25

bromopyruvate and Necrosis

bromopyruvate has been researched along with Necrosis in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, TC; Hofman, FM; Myint, PT; Nouri Nigjeh, E; Schönthal, AH; Wang, W; Yu, J; Zandi, E1
Aller, P; Boyano-Adánez, Mdel C; Brea, R; Calviño, E; de Blas, E; Estañ, MC; Rial, E; Sánchez-Martín, C1
Abd-Allah, AA; Ahmed, AS; Ahmed, NS; Amer, WH; El Sayed, SM; Hamed, AR; Helmy Nabo, MM; Mahmoud, AG; Mohamed, WG; Seddik, MA1
Gong, L; Leng, X; Peng, J; Wei, Y; Yu, X1
Atkins, KA; Baker, WD; Byrne, FL; Chow, JD; Healy, ME; Hoehn, KL; Lancaster, JM; Marchion, DC; Modesitt, SC; Moley, KH; Poon, IK; Ravichandran, KS; Slack-Davis, JK; Tomsig, JL1
Nickoloff, BJ; Qin, JZ; Xin, H1
Pedersen, PL1

Reviews

2 review(s) available for bromopyruvate and Necrosis

ArticleYear
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.
    Chinese journal of cancer, 2014, Volume: 33, Issue:7

    Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplasms; Male; Melanoma; Necrosis; Neovascularization, Pathologic; Pleural Neoplasms; Prognosis; Pyruvates; Treatment Outcome

2014
The cancer cell's "power plants" as promising therapeutic targets: an overview.
    Journal of bioenergetics and biomembranes, 2007, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Death; Cell Respiration; Cytochrome c Group; Energy Metabolism; Glycolysis; Humans; Mitochondria; Necrosis; Neoplasms; Pyruvates

2007

Other Studies

5 other study(ies) available for bromopyruvate and Necrosis

ArticleYear
A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells.
    Cancer letters, 2017, 08-01, Volume: 400

    Topics: Adenosine Triphosphate; Alkylation; Antineoplastic Agents; Antioxidants; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; HCT116 Cells; Humans; MCF-7 Cells; Monocarboxylic Acid Transporters; Monoterpenes; Necrosis; Neoplasms; Pyruvates; RNA Interference; Signal Transduction; Symporters; Transfection

2017
Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Drug Synergism; Energy Metabolism; Enzyme Activation; Glycolysis; Humans; Leukemia, Myeloid; MAP Kinase Signaling System; Mitochondria; Necrosis; Neoplasm Proteins; Oxidative Phosphorylation; Oxidative Stress; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyruvates; Up-Regulation

2014
3-Bromopyruvic acid, a hexokinase II inhibitor, is an effective antitumor agent on the hepatoma cells : in vitro and in vivo findings.
    Anti-cancer agents in medicinal chemistry, 2014, Volume: 14, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hexokinase; Humans; Lethal Dose 50; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Necrosis; Pyruvates

2014
Metabolic vulnerabilities in endometrial cancer.
    Cancer research, 2014, Oct-15, Volume: 74, Issue:20

    Topics: Animals; Antineoplastic Agents; Case-Control Studies; Cell Line, Tumor; Cell Survival; Coenzyme A; Endometrial Neoplasms; Endometrium; Female; Glucose Transport Proteins, Facilitative; Glycolysis; Hexokinase; Humans; Lipogenesis; Mice, Nude; Middle Aged; Molecular Targeted Therapy; Necrosis; Pyruvate Kinase; Pyruvates; Reactive Oxygen Species; Tumor Burden; Xenograft Model Antitumor Assays

2014
3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines.
    Biochemical and biophysical research communications, 2010, May-28, Volume: 396, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Glutathione; Humans; Melanoma; Membrane Potential, Mitochondrial; Necrosis; Pyruvates; Skin Neoplasms; Superoxides

2010
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