Compounds > bromopyruvate
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bromopyruvate and Lung Neoplasms

bromopyruvate has been researched along with Lung Neoplasms in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dai, K; Leonardi, D; Radin, DP1
Abd-Allah, AA; Ahmed, AS; Ahmed, NS; Amer, WH; El Sayed, SM; Hamed, AR; Helmy Nabo, MM; Mahmoud, AG; Mohamed, WG; Seddik, MA1
Kalyanaraman, B; Komas, SM; Lubet, RA; Pan, J; Wang, Y; You, M; Zhang, Q1
Chavez, V; Orue, A; Rieber, M; Strasberg-Rieber, M1
Buijs, M; Geschwind, JF; Kutiyanwala, F; Kutiyanwala, M; Syed, L; Vali, M; Vossen, JA1
Lubet, RA; North, PE; Pan, J; Wang, Y; Yang, S; You, M; Zhang, Q1
Geschwind, JF; Ko, YH; Magee, C; Pedersen, PL; Torbenson, MS1

Reviews

1 review(s) available for bromopyruvate and Lung Neoplasms

ArticleYear
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.
    Chinese journal of cancer, 2014, Volume: 33, Issue:7

    Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplasms; Male; Melanoma; Necrosis; Neovascularization, Pathologic; Pleural Neoplasms; Prognosis; Pyruvates; Treatment Outcome

2014

Other Studies

6 other study(ies) available for bromopyruvate and Lung Neoplasms

ArticleYear
PINK1 depletion sensitizes non-small cell lung cancer to glycolytic inhibitor 3-bromopyruvate: Involvement of ROS and mitophagy.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:6

    Topics: A549 Cells; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Glycolysis; Humans; Lung; Lung Neoplasms; Mitochondria; Mitophagy; Parkinson Disease; Protein Kinases; Pyruvates; Reactive Oxygen Species; Signal Transduction; Ubiquitin-Protein Ligases

2019
Enhanced antitumor activity of 3-bromopyruvate in combination with rapamycin in vivo and in vitro.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Energy Metabolism; Enzyme Inhibitors; Female; Glycolysis; Humans; Lung Neoplasms; Mice; Mice, Inbred A; Mitochondria; Oxygen Consumption; Pyruvates; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
    BMC cancer, 2016, 11-18, Volume: 16, Issue:1

    Topics: A549 Cells; Acetylcysteine; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; GTP Phosphohydrolases; Humans; Lung Neoplasms; Melanoma; Membrane Proteins; Mutation; Proto-Oncogene Proteins p21(ras); Pyruvates; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53

2016
Development of a new orthotopic animal model of metastatic liver cancer in the rabbit VX2 model: effect on metastases after partial hepatectomy, intra-arterial treatment with 3-bromopyruvate and chemoembolization.
    Clinical & experimental metastasis, 2008, Volume: 25, Issue:7

    Topics: Animals; Chemoembolization, Therapeutic; Disease Models, Animal; Hepatectomy; Infusions, Intra-Arterial; Liver Neoplasms, Experimental; Lung Neoplasms; Pyruvates; Rabbits

2008
Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Administration, Inhalation; Aerosols; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Down-Regulation; Drug Evaluation, Preclinical; Female; Humans; Lung Neoplasms; Mice; Models, Biological; Pyruvates

2012
Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.
    Cancer research, 2002, Jul-15, Volume: 62, Issue:14

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Embolization, Therapeutic; Injections, Intra-Arterial; Liver Neoplasms, Experimental; Lung Neoplasms; Neoplasm Transplantation; Pyruvates; Rabbits

2002