bromopyruvate has been researched along with Hepatocellular Carcinoma in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 14 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, Y; Cho, EJ; Cho, H; Cho, YY; Jo, A; Kim, JB; Kim, YJ; Lee, JH; Lee, M; Lee, S; Nam, JY; Yoon, JH; Yu, SJ | 1 |
| Cho, EJ; Cho, H; Cho, YY; Kim, K; Kim, YJ; Lee, JH; Lee, YB; Yoon, JH; Youn, H; Yu, SJ | 1 |
| Cho, EJ; Cho, YY; Kim, K; Kim, YJ; Lee, JH; Lee, YB; Na, J; Yoo, JJ; Yoon, JH; Youn, H; Yu, SJ | 1 |
| Jiang, C; Jiang, Z; Li, H; Liu, H; Wu, C; Zhang, Y; Zhao, S | 1 |
| Abd-Allah, AA; Ahmed, AS; Ahmed, NS; Amer, WH; El Sayed, SM; Hamed, AR; Helmy Nabo, MM; Mahmoud, AG; Mohamed, WG; Seddik, MA | 1 |
| Gong, L; Leng, X; Peng, J; Wei, Y; Yu, X | 1 |
| Ishige, N; Motoyoshi, Y; Shinozaki, F; Sugiyama, T; Tomizawa, M; Yamamoto, S | 1 |
| Almeida, FC; Da Poian, AT; da-Silva, WS; dos Santos, RS; El-Bacha, T; Galina, A; Kyaw, N; Pereira da Silva, AP | 1 |
| Ahn, KJ; Kim, HM; Kim, JA; Kim, JS; Kim, SJ; Lee, JD; Lee, JM; Park, JH | 1 |
| Buijs, M; Cole, RN; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Ota, S; Rao, PP; Syed, LH; Tchernyshyov, I; Vali, M; Vossen, JA | 1 |
| Buijs, M; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Kwak, BK; Loffroy, R; Ota, S; Rao, PP; Syed, LH; Vali, M | 1 |
| Choi, YH; Chung, H; Chung, JW; Jae, HJ; Kim, HC; Kim, W; Kim, YI; Park, JH; So, YH; Son, KR; Yoon, CJ; Yoon, JH | 1 |
| Cho, EJ; Jang, ES; Jang, JJ; Kim, YJ; Kwak, MS; Lee, HS; Lee, JH; Myung, SJ; Yoon, JH; Yu, SJ | 1 |
| Corbin, DJ; Ko, YH; Lee, MJ; Pedersen, PL; Verhoeven, HA; Vogl, TJ | 1 |
| Cho, EJ; Jang, ES; Kim, CY; Kim, YJ; Kwak, MS; Lee, HS; Lee, JH; Yang, JI; Yoon, JH; Yu, SJ | 1 |
| Goldberg, SN | 1 |
| Buijs, M; Carson, KA; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Rao, PP; Torbenson, MS; Vali, M | 1 |
| Di Bisceglie, AM; Harrison, SA | 1 |
| Foubister, V | 1 |
| Hullihen, J; Ko, YH; Pedersen, PL; Pomper, MG; Rini, DA; Smith, BL; Torbenson, MS; Wang, Y | 1 |
| Cheon, GJ; Jeong, JM; Kim, W; Lee, HS; Lee, TS; Park, SC; Yang, JI; Yoon, JH | 1 |
1 review(s) available for bromopyruvate and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.
Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplasms; Male; Melanoma; Necrosis; Neovascularization, Pathologic; Pleural Neoplasms; Prognosis; Pyruvates; Treatment Outcome | 2014 |
20 other study(ies) available for bromopyruvate and Hepatocellular Carcinoma
| Article | Year |
|---|---|
3-bromopyruvate and buthionine sulfoximine effectively kill anoikis-resistant hepatocellular carcinoma cells.
Topics: Anoikis; Antineoplastic Agents; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Epithelial-Mesenchymal Transition; Hep G2 Cells; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Pyruvates; Reactive Oxygen Species; Sorafenib | 2017 |
Carbonic anhydrase-IX inhibition enhances the efficacy of hexokinase II inhibitor for hepatocellular carcinoma in a murine model.
Topics: Acetazolamide; Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carcinoma, Hepatocellular; Hep G2 Cells; Hexokinase; Humans; Liver Neoplasms, Experimental; Male; Mice, Inbred BALB C; Mice, Nude; Pyruvates | 2019 |
Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Hexokinase; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Prognosis; Pyruvates; Sorafenib; Survival Analysis; Treatment Outcome; Up-Regulation; Xenograft Model Antitumor Assays | 2019 |
[3-bromopyruvate enhances cisplatin sensitivity of hepatocellular carcinoma cells in vitro].
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cisplatin; Hep G2 Cells; Humans; Liver Neoplasms; Pyruvates; X-Linked Inhibitor of Apoptosis Protein | 2014 |
3-Bromopyruvic acid, a hexokinase II inhibitor, is an effective antitumor agent on the hepatoma cells : in vitro and in vivo findings.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hexokinase; Humans; Lethal Dose 50; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Necrosis; Pyruvates | 2014 |
Suppressive effects of 3-bromopyruvate on the proliferation and the motility of hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin D1; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Pyruvates | 2016 |
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate.
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Energy Metabolism; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Lactic Acid; Liver Neoplasms; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Succinate Dehydrogenase | 2009 |
Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells : ROS-mediated cell death by 3-BrPA.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hexokinase; Humans; Liver Neoplasms; Mitochondria; Pyruvates; Reactive Oxygen Species | 2008 |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Electrophoresis, Gel, Two-Dimensional; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunoblotting; Immunoprecipitation; Liver Neoplasms; Pyruvates; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured | 2009 |
3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines.
Topics: Adenosine Triphosphate; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum; Humans; Liver Neoplasms; Pyruvates; Stress, Physiological | 2010 |
Novel intraarterial therapy for liver cancer using ethylbromopyruvate dissolved in an iodized oil.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Embolization, Therapeutic; Hemostatics; Humans; Injections, Intra-Arterial; Iodized Oil; Liver Neoplasms; Pyruvates; Rabbits; Treatment Outcome | 2011 |
Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hexokinase; Humans; Liver Neoplasms; Pyruvates; RNA, Small Interfering; Sulfonamides | 2011 |
A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside.
Topics: Adolescent; Ammonia; Antineoplastic Agents, Alkylating; Carcinoma, Hepatocellular; Energy Metabolism; Fatal Outcome; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Molecular Structure; Positron-Emission Tomography; Pyruvates; Translational Research, Biomedical; Urea; Uric Acid | 2012 |
Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Bacitracin; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum Stress; Hexokinase; Humans; Immunoblotting; Indoles; Male; Mice; Microvessels; Protein Disulfide-Isomerases; Pyruvates; Statistics, Nonparametric | 2012 |
Science to practice: what do molecular biologic studies in rodent models add to our understanding of interventional oncologic procedures including percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists?
Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Liver Neoplasms; Proto-Oncogene Mas; Pyruvates; RNA, Small Interfering | 2012 |
Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Injections; Liver Neoplasms; Luminescent Measurements; Mice; Mice, Nude; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Pyruvates; Real-Time Polymerase Chain Reaction; RNA, Small Interfering | 2012 |
A new approach to therapy for hepatocellular carcinoma?
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Humans; Injections, Intra-Arterial; Liver Neoplasms; Pyruvates | 2003 |
Energy blocker to treat liver cancer.
Topics: Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Energy Metabolism; Humans; Liver Neoplasms; Pyruvates | 2002 |
Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Inhibitors; Female; Glucose; Humans; Liver Neoplasms, Experimental; Neoplasm Transplantation; Pyruvates; Rats; Rats, Sprague-Dawley; Survival Rate | 2004 |
Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma.
Topics: Animals; Annexin A5; Apoptosis; Azirines; Carcinoma, Hepatocellular; Enzyme Inhibitors; Flow Cytometry; Hexokinase; Humans; Hypoxia; Immunoblotting; Immunoprecipitation; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mitochondria; Phosphatidylcholines; Pyruvate Dehydrogenase Complex; Pyruvates; Tissue Distribution; Tumor Cells, Cultured | 2007 |