bromopyruvate and Disease Models, Animal

Topics: Animals; Apoptosis; Autophagy; Cell Hypoxia; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycolysis; Hexokinase; Humans; Hypoxia; Mice; Multiple Myeloma; Pyruvates; Stress, Physiological; Xenograft Model Antitumor Assays

Topics: Animals; Apoptosis; Autophagy; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Gene Silencing; Glucose; Glucose Transporter Type 4; Humans; Mice; Mitogen-Activated Protein Kinases; Pinocytosis; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Pyruvates; RNA Splicing; Signal Transduction; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Male; Mice; Prostatic Neoplasms, Castration-Resistant; Pyruvates; Xenograft Model Antitumor Assays

Topics: Acetates; Affinity Labels; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Disease Models, Animal; Female; Mice; Oxylipins; Plant Growth Regulators; Pyruvates; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Antioxidants; Autophagy; Carcinoma, Ehrlich Tumor; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Glycolysis; Hexokinase; Hydroxychloroquine; Kupffer Cells; Liver; Mice; Mice, Inbred BALB C; Oxidative Stress; Pyruvates

Topics: Animals; Disease Models, Animal; Male; Mitochondria; Monocrotaline; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyruvates; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases

Topics: Animals; Cell Line; Cell Proliferation; China; Disease Models, Animal; Fibroblasts; Fibrosis; Glycolysis; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Myofibroblasts; Pyruvates; Rats; Signal Transduction; Transforming Growth Factor beta1; Ureteral Obstruction; Urinary Tract

Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Glycolysis; Interferon-gamma; Interleukin-17; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Pyruvates; Th1 Cells; Th17 Cells

Topics: Animals; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Fungi; Glycolysis; Hexokinase; Humans; Melanoma; Mitochondria; Multiple Myeloma; Neoplasms; Pyruvates; Pyruvic Acid

Topics: Animals; Apoptosis; Cardiac Catheterization; Disease Models, Animal; Enzyme Inhibitors; Glycolysis; Hypertension, Pulmonary; Immunohistochemistry; Male; Pulmonary Wedge Pressure; Pyruvates; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vascular Resistance

Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Repositioning; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Mice, Inbred BALB C; Microbial Viability; Mycobacterium tuberculosis; Pyruvates; Staphylococcal Infections; Staphylococcus aureus; Transferrin; Treatment Outcome

Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Humans; Male; Mice; Pancreatic Neoplasms; Pyruvates; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

Topics: Acute Kidney Injury; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Kidney; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Pyruvates

Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Diseases; Cell Differentiation; Dendritic Cells; Disease Models, Animal; Disease Progression; Hexokinase; Lymphocyte Activation; Lymphocyte Count; Mice; Pyruvates; Synovial Membrane; T-Lymphocytes, Regulatory; Th17 Cells

Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glycolysis; Mammary Neoplasms, Experimental; Pyruvates; Rats; Rats, Inbred Lew

Topics: Animals; Chemoembolization, Therapeutic; Disease Models, Animal; Hepatectomy; Infusions, Intra-Arterial; Liver Neoplasms, Experimental; Lung Neoplasms; Pyruvates; Rabbits

Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Female; Genetic Therapy; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Mice; Neoplastic Stem Cells; Oxidative Stress; Pyruvates; Rats; Rats, Sprague-Dawley; Transfection

Topics: Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Glycolysis; Humans; Lethal Dose 50; Lymphoma, Non-Hodgkin; Male; Mice; Mice, SCID; Pyruvates; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Liver Neoplasms; Proto-Oncogene Mas; Pyruvates; RNA, Small Interfering

Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Injections; Liver Neoplasms; Luminescent Measurements; Mice; Mice, Nude; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Pyruvates; Real-Time Polymerase Chain Reaction; RNA, Small Interfering

Topics: Animals; Antineoplastic Agents; Catheterization; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Infusions, Intra-Arterial; Injections, Intra-Arterial; Liver Neoplasms, Experimental; Maximum Tolerated Dose; Pyruvate Dehydrogenase Complex; Pyruvates; Rabbits