Page last updated: 2024-08-25

bromopyruvate and Colorectal Cancer

bromopyruvate has been researched along with Colorectal Cancer in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Alboghobeish, S; Behmanesh, B; Khodayar, MJ; Mahdavinia, M; Nikravesh, H; Teimoori, A; Zeidooni, L1
Chong, D; Huo, Q; Liu, F; Liu, H; Ma, L; Zhang, P; Zhang, Z; Zhao, S; Zheng, H1
Azevedo-Silva, J; Baltazar, F; Casal, M; Côrte-Real, M; Ferro, S; Preto, A1
Azevedo-Silva, J; Casal, M; Pereira-Vieira, J; Preto, A; Queirós, O1
Coomber, BL; Ho, N; Morrison, J; Silva, A1
Angenendt, P; Cheong, I; Diaz, LA; Kinzler, KW; Lengauer, C; Markowitz, S; Pagliarini, R; Papadopoulos, N; Rago, C; Rajagopalan, H; Schmidt, K; Velculescu, VE; Vogelstein, B; Willson, JK; Yun, J; Zhou, S1
Hu, Y; Huang, P; Tang, Z; Wu, W; Xu, R; Yang, J; Yuan, S; Yun, J; Zeng, Z; Zhang, H1

Other Studies

7 other study(ies) available for bromopyruvate and Colorectal Cancer

ArticleYear
The combined effect of dichloroacetate and 3-bromopyruvate on glucose metabolism in colorectal cancer cell line, HT-29; the mitochondrial pathway apoptosis.
    BMC cancer, 2021, Aug-07, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dichloroacetic Acid; Drug Synergism; Fluorouracil; Glucose; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Mitochondria; Models, Biological; Pyruvates

2021
Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
    Anti-cancer drugs, 2017, Volume: 28, Issue:8

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Drug Synergism; Female; Fluorouracil; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pyruvates; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2017
Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications.
    Oncotarget, 2016, Oct-25, Volume: 7, Issue:43

    Topics: Acetates; Biological Transport; Cell Line, Tumor; Colorectal Neoplasms; Glycolysis; Humans; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvates; Symporters

2016
MCT1, MCT4 and CD147 expression and 3-bromopyruvate toxicity in colorectal cancer cells are modulated by the extracellular conditions.
    Biological chemistry, 2019, 05-27, Volume: 400, Issue:6

    Topics: Antineoplastic Agents; Basigin; Cell Hypoxia; Cell Line, Tumor; Colorectal Neoplasms; Glucose; Glycolysis; Humans; Hydrogen-Ion Concentration; Monocarboxylic Acid Transporters; Muscle Proteins; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvates; Symporters

2019
The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression.
    Bioscience reports, 2016, Jan-06, Volume: 36, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucose; Hexokinase; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvates

2016
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
    Science (New York, N.Y.), 2009, Sep-18, Volume: 325, Issue:5947

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Targeting; Genes, ras; Glucose; Glucose Transporter Type 1; Glycolysis; Humans; Lactic Acid; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Pyruvates; Transplantation, Heterologous

2009
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.
    Journal of bioenergetics and biomembranes, 2012, Volume: 44, Issue:1

    Topics: Adenosine Triphosphate; Apoptosis; Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Humans; Immunohistochemistry; Liver Neoplasms; Pyruvates

2012