Compounds > bromopyruvate

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bromopyruvate and Cancer of Liver

bromopyruvate has been researched along with Cancer of Liver in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (27.78)	29.6817
2010's	13 (72.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, Y; Cho, EJ; Cho, H; Cho, YY; Jo, A; Kim, JB; Kim, YJ; Lee, JH; Lee, M; Lee, S; Nam, JY; Yoon, JH; Yu, SJ	1
Cho, EJ; Cho, YY; Kim, K; Kim, YJ; Lee, JH; Lee, YB; Na, J; Yoo, JJ; Yoon, JH; Youn, H; Yu, SJ	1
Jiang, C; Jiang, Z; Li, H; Liu, H; Wu, C; Zhang, Y; Zhao, S	1
Gong, L; Leng, X; Peng, J; Wei, Y; Yu, X	1
Ishige, N; Motoyoshi, Y; Shinozaki, F; Sugiyama, T; Tomizawa, M; Yamamoto, S	1
Dyląg, M; Goffeau, A; Ko, YH; Lis, P; Niedźwiecka, K; Pedersen, PL; Ułaszewski, S	1
Almeida, FC; Da Poian, AT; da-Silva, WS; dos Santos, RS; El-Bacha, T; Galina, A; Kyaw, N; Pereira da Silva, AP	1
Ahn, KJ; Kim, HM; Kim, JA; Kim, JS; Kim, SJ; Lee, JD; Lee, JM; Park, JH	1
Buijs, M; Cole, RN; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Ota, S; Rao, PP; Syed, LH; Tchernyshyov, I; Vali, M; Vossen, JA	1
Buijs, M; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Kwak, BK; Loffroy, R; Ota, S; Rao, PP; Syed, LH; Vali, M	1
Choi, YH; Chung, H; Chung, JW; Jae, HJ; Kim, HC; Kim, W; Kim, YI; Park, JH; So, YH; Son, KR; Yoon, CJ; Yoon, JH	1
Cho, EJ; Jang, ES; Jang, JJ; Kim, YJ; Kwak, MS; Lee, HS; Lee, JH; Myung, SJ; Yoon, JH; Yu, SJ	1
Corbin, DJ; Ko, YH; Lee, MJ; Pedersen, PL; Verhoeven, HA; Vogl, TJ	1
Hu, Y; Huang, P; Tang, Z; Wu, W; Xu, R; Yang, J; Yuan, S; Yun, J; Zeng, Z; Zhang, H	1
Goldberg, SN	1
Buijs, M; Carson, KA; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Rao, PP; Torbenson, MS; Vali, M	1
Di Bisceglie, AM; Harrison, SA	1
Foubister, V	1

Reviews

1 review(s) available for bromopyruvate and Cancer of Liver

Article	Year
The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate. Molecules (Basel, Switzerland), 2016, Dec-15, Volume: 21, Issue:12 Topics: Antineoplastic Agents; Energy Metabolism; Glycolysis; Hexokinase; Humans; Liver Neoplasms; Mitochondria; Multiple Myeloma; Oxidative Phosphorylation; Pyruvates	2016

Other Studies

17 other study(ies) available for bromopyruvate and Cancer of Liver

Article	Year
3-bromopyruvate and buthionine sulfoximine effectively kill anoikis-resistant hepatocellular carcinoma cells. PloS one, 2017, Volume: 12, Issue:3 Topics: Anoikis; Antineoplastic Agents; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Epithelial-Mesenchymal Transition; Hep G2 Cells; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Pyruvates; Reactive Oxygen Species; Sorafenib	2017
Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma. International journal of molecular sciences, 2019, Mar-14, Volume: 20, Issue:6 Topics: Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Hexokinase; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Prognosis; Pyruvates; Sorafenib; Survival Analysis; Treatment Outcome; Up-Regulation; Xenograft Model Antitumor Assays	2019
[3-bromopyruvate enhances cisplatin sensitivity of hepatocellular carcinoma cells in vitro]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:1 Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cisplatin; Hep G2 Cells; Humans; Liver Neoplasms; Pyruvates; X-Linked Inhibitor of Apoptosis Protein	2014
3-Bromopyruvic acid, a hexokinase II inhibitor, is an effective antitumor agent on the hepatoma cells : in vitro and in vivo findings. Anti-cancer agents in medicinal chemistry, 2014, Volume: 14, Issue:5 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hexokinase; Humans; Lethal Dose 50; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Necrosis; Pyruvates	2014
Suppressive effects of 3-bromopyruvate on the proliferation and the motility of hepatocellular carcinoma cells. Oncology reports, 2016, Volume: 35, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin D1; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Pyruvates	2016
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate. The Biochemical journal, 2009, Feb-01, Volume: 417, Issue:3 Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Energy Metabolism; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Lactic Acid; Liver Neoplasms; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Succinate Dehydrogenase	2009
Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells : ROS-mediated cell death by 3-BrPA. Journal of bioenergetics and biomembranes, 2008, Volume: 40, Issue:6 Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hexokinase; Humans; Liver Neoplasms; Mitochondria; Pyruvates; Reactive Oxygen Species	2008
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death. Anticancer research, 2009, Volume: 29, Issue:12 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Electrophoresis, Gel, Two-Dimensional; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunoblotting; Immunoprecipitation; Liver Neoplasms; Pyruvates; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured	2009
3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines. Anticancer research, 2010, Volume: 30, Issue:3 Topics: Adenosine Triphosphate; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum; Humans; Liver Neoplasms; Pyruvates; Stress, Physiological	2010
Novel intraarterial therapy for liver cancer using ethylbromopyruvate dissolved in an iodized oil. Academic radiology, 2011, Volume: 18, Issue:4 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Embolization, Therapeutic; Hemostatics; Humans; Injections, Intra-Arterial; Iodized Oil; Liver Neoplasms; Pyruvates; Rabbits; Treatment Outcome	2011
Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis. Acta pharmacologica Sinica, 2011, Volume: 32, Issue:7 Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hexokinase; Humans; Liver Neoplasms; Pyruvates; RNA, Small Interfering; Sulfonamides	2011
A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside. Journal of bioenergetics and biomembranes, 2012, Volume: 44, Issue:1 Topics: Adolescent; Ammonia; Antineoplastic Agents, Alkylating; Carcinoma, Hepatocellular; Energy Metabolism; Fatal Outcome; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Molecular Structure; Positron-Emission Tomography; Pyruvates; Translational Research, Biomedical; Urea; Uric Acid	2012
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. Journal of bioenergetics and biomembranes, 2012, Volume: 44, Issue:1 Topics: Adenosine Triphosphate; Apoptosis; Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Humans; Immunohistochemistry; Liver Neoplasms; Pyruvates	2012
Science to practice: what do molecular biologic studies in rodent models add to our understanding of interventional oncologic procedures including percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists? Radiology, 2012, Volume: 262, Issue:3 Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Liver Neoplasms; Proto-Oncogene Mas; Pyruvates; RNA, Small Interfering	2012
Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists. Radiology, 2012, Volume: 262, Issue:3 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Injections; Liver Neoplasms; Luminescent Measurements; Mice; Mice, Nude; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Pyruvates; Real-Time Polymerase Chain Reaction; RNA, Small Interfering	2012
A new approach to therapy for hepatocellular carcinoma? Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:2 Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Humans; Injections, Intra-Arterial; Liver Neoplasms; Pyruvates	2003
Energy blocker to treat liver cancer. Drug discovery today, 2002, Sep-15, Volume: 7, Issue:18 Topics: Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Energy Metabolism; Humans; Liver Neoplasms; Pyruvates	2002