bromopyruvate has been researched along with Breast Cancer in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 12 (75.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Almeida, A; Azevedo-Silva, J; Baltazar, F; Casal, M; Ko, YH; Pedersen, PL; Preto, A; Queirós, O; Tavares-Valente, D | 1 |
| Darvishi, P; Pourfathollah, AA; Yousefi, S; Yousefi, Z | 1 |
| Jiang, CC; Li, L; Li, QX; Liu, F; Liu, H; Wang, XZ; Wang, ZK; Zhang, P; Zheng, HL | 1 |
| Chen, Y; Li, Q; Liu, H; Liu, X; Pan, Q; Wei, L; Zhang, S; Zhang, X; Zhao, S; Zhou, L | 1 |
| Bartosz, G; Jatczak-Pawlik, I; Pulaski, L; Sadowska-Bartosz, I; Sobalska-Kwapis, M; Strapagiel, D | 1 |
| Buijs, M; Geschwind, JF; Kwak, BK; Ota, S; Wijlemans, JW | 1 |
| Rieber, M; Strasberg-Rieber, M | 1 |
| Cheng, X; Jiang, CC; Jiang, ZW; Liu, H; Liu, Z; Wu, CZ; Zhang, QW; Zhang, YY; Zhao, SR | 1 |
| Feng, X; Liu, Q; Wang, P; Wang, X; Zhang, Y | 1 |
| Cai, S; Du, J; Liu, G; Wang, H; Wang, X; Wu, B; Wu, L; Xu, J; Yuan, W | 1 |
| Azevedo-Silva, J; Baltazar, F; Casal, M; Pedersen, PL; Preto, A; Queirós, O; Ribeiro, A; Young, KH | 1 |
| Al Marzabani, MM; Attia, YM; El-Abhar, HS; Shouman, SA | 1 |
| Bartosz, G; Gajewska, A; Kwiatkowska, E; Sadowska-Bartosz, I; Soszyński, M; Wojtala, M | 1 |
| Elangovan, S; Ganapathy, V; Gopal, E; Itagaki, S; Karunakaran, SK; Prasad, PD; Thangaraju, M | 1 |
| Liu, XH; Wang, YL; Zheng, XF | 1 |
| Azevedo-Silva, J; Baltazar, F; Casal, M; Ko, YH; Moreira, R; Pacheco, A; Pedersen, PL; Pedro, M; Pinheiro, C; Preto, A; Queirós, O | 1 |
16 other study(ies) available for bromopyruvate and Breast Cancer
| Article | Year |
|---|---|
Cytoskeleton disruption by the metabolic inhibitor 3-bromopyruvate: implications in cancer therapy.
Topics: Actins; Breast Neoplasms; Cell Line, Tumor; Cytoskeleton; Female; Humans; Pyruvates; Tubulin | 2022 |
Effect of methyl jasmonate and 3-bromopyruvate combination therapy on mice bearing the 4 T1 breast cancer cell line.
Topics: Acetates; Affinity Labels; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Disease Models, Animal; Female; Mice; Oxylipins; Plant Growth Regulators; Pyruvates; Xenograft Model Antitumor Assays | 2020 |
[Monocarboxylate transporter 1 enhances the sensitivity of breast cancer cells to 3-bromopyruvate in vitro].
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Monocarboxylic Acid Transporters; Pyruvates; Symporters | 2017 |
3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Pyrazoles; Pyrimidines; Pyruvates; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation; Xenograft Model Antitumor Assays | 2018 |
3-Bromopyruvate induces expression of antioxidant genes.
Topics: Antioxidants; Breast Neoplasms; Female; Humans; Oxidative Stress; Pyruvates | 2019 |
Antiglycolytic therapy combined with an image-guided minimally invasive delivery strategy for the treatment of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Glycolysis; Humans; Injections, Intralesional; Mammography; Mice; Mice, Nude; Pyruvates; Treatment Outcome; Ultrasonography, Interventional | 2013 |
p53 inactivation decreases dependence on estrogen/ERK signalling for proliferation but promotes EMT and susceptility to 3-bromopyruvate in ERα+ breast cancer MCF-7 cells.
Topics: Breast Neoplasms; Cell Proliferation; Epithelial-Mesenchymal Transition; Estrogen Receptor alpha; Female; Genes, p53; Humans; MAP Kinase Signaling System; MCF-7 Cells; Pyruvate Dehydrogenase Complex; Pyruvates | 2014 |
3-Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl-1 through the PI3K/Akt signaling pathway.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Down-Regulation; Female; Hexokinase; Humans; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyruvates; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2014 |
Energy metabolism targeted drugs synergize with photodynamic therapy to potentiate breast cancer cell death.
Topics: Acetylcysteine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Deoxyglucose; Female; Free Radical Scavengers; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Kinase 4; Mitochondrial Membranes; p38 Mitogen-Activated Protein Kinases; Photochemotherapy; Photosensitizing Agents; Pyruvates; Reactive Oxygen Species | 2014 |
The reversal effects of 3-bromopyruvate on multidrug resistance in vitro and in vivo derived from human breast MCF-7/ADR cells.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Pyruvates; Xenograft Model Antitumor Assays | 2014 |
The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH.
Topics: Antineoplastic Agents; Basigin; Breast Neoplasms; Cell Line, Tumor; Cytotoxins; Enzyme Inhibitors; Female; Gene Expression Regulation; Glycosylation; Humans; Hydrogen-Ion Concentration; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Proteins; Protein Transport; Pyruvates; Symporters; Tumor Microenvironment | 2015 |
Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Glycolysis; Humans; Mice; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Pyruvates; Tamoxifen; Xenograft Model Antitumor Assays | 2015 |
Effect of 3-bromopyruvate acid on the redox equilibrium in non-invasive MCF-7 and invasive MDA-MB-231 breast cancer cells.
Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Female; Glutathione Reductase; Glutathione Transferase; Humans; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Proteins; Oxidation-Reduction; Pyruvates; Reactive Oxygen Species | 2016 |
Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Cation Transport Proteins; Cell Line; Cell Line, Tumor; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylases; Humans; Mice; Monocarboxylic Acid Transporters; Pyruvates; Rats; Recombinant Proteins; Retinal Pigment Epithelium; Transfection; Xenopus laevis | 2009 |
Inhibitive effect of 3-bromopyruvic acid on human breast cancer MCF-7 cells involves cell cycle arrest and apoptotic induction.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Female; Flow Cytometry; G2 Phase; Humans; Immunohistochemistry; Molecular Structure; Pyruvates; S Phase | 2009 |
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Butyrates; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvates; Tetrazolium Salts; Thiazoles | 2012 |