bromopyruvate has been researched along with Benign Neoplasms in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 4 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, H; Huang, J; Li, P; Luo, Y; Shang, T; Wang, D; Wang, X; Wang, Z; Wen, J; Zhang, L; Zhou, D | 1 |
| Koszła, O; Koziorowska, A; Koziorowski, M; Majchrowicz, L; Mytych, J; Sołek, P; Łannik, E | 1 |
| Cao, Y; Chen, H; He, Y; Li, W; Wang, D; Wang, Z; Xu, L; Yao, H; Zhang, L; Zhou, D | 1 |
| Chen, X; Deng, Y; Hong, L; Huang, Y; Ji, J; Jin, Q; Song, P | 1 |
| Chen, TC; Hofman, FM; Myint, PT; Nouri Nigjeh, E; Schönthal, AH; Wang, W; Yu, J; Zandi, E | 1 |
| Goel, Y; Kumar, A; Pandey, SK; Singh, SM; Singh, VK; Yadav, S | 1 |
| Gamian, A; Szczuka, I; Terlecki, G | 1 |
| El Sayed, SM | 1 |
| Baltzer, J | 1 |
| Casal, M; Ko, YH; Niedźwiecka, K; Pedersen, PL; Ułaszewski, S | 1 |
| Abdelaal, EA; Abdelmoaty, MA; Ahmed, NS; El Sawy, SA; El Sayed, SM; Fouad, AM; Gabr, AG; Hashim, MS; Hemdan, SB; Kadry, ZM; Mahmoud, AA; Nabo, MM; Omran, FM; Yousif, RS | 1 |
| Aldrich-Wright, JR; Garbutcheon-Singh, KB; Harper, BW; Myers, S | 1 |
| Galina, A | 1 |
| Karagiannis, TC; Ngo, H; Tortorella, SM; Ververis, K | 1 |
| Basaga, H; Bodur, C; Karakas, B; Tezil, T; Timucin, AC | 1 |
| Hu, X; Liu, H; Pan, T; Tan, R; Tan, W; Wang, S; Wang, Y; Yu, H; Zhong, Z | 1 |
| Ko, YH; Mathupala, SP; Pedersen, PL | 1 |
| Chen, Z; Huang, P; Lu, W; Zhang, H | 1 |
| Buijs, M; Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R; Kwak, BK; Loffroy, R; Ota, S; Rao, PP; Syed, LH; Vali, M | 1 |
| Shoshan, MC | 1 |
| van Griensven, LJ; Verhoeven, HA | 1 |
| Cardaci, S; Ciriolo, MR; Desideri, E | 1 |
| Ganapathy-Kanniappan, S; Geschwind, JF; Kunjithapatham, R | 1 |
| Bhalla, KN; Carew, JS; Feng, L; Huang, P; Keating, MJ; Pelicano, H; Xu, RH; Zhou, Y | 1 |
| Pedersen, PL | 1 |
9 review(s) available for bromopyruvate and Benign Neoplasms
| Article | Year |
|---|---|
3-Bromopyruvate as a potential pharmaceutical in the light of experimental data.
Topics: Animals; Antineoplastic Agents; Apoptosis; Energy Metabolism; Glycolysis; Humans; Mice; Neoplasms; Oxidative Phosphorylation; Pyruvates | 2017 |
The Warburg effect: molecular aspects and therapeutic possibilities.
Topics: Antineoplastic Agents; Dichloroacetic Acid; Epigenesis, Genetic; Genes; Glycolysis; Humans; Lactic Acid; Neoplasms; Pyruvates | 2015 |
The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance.
Topics: Antineoplastic Agents; Drug Design; Drug Resistance, Neoplasm; Fatty Acids; Humans; Indazoles; Metabolic Engineering; Neoplasms; Oxidative Phosphorylation; Pyruvates | 2017 |
Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Hexokinase; Humans; Mitochondria; Neoplasms; Phosphorylation; Protein Isoforms; Pyruvates | 2009 |
3-bromopyruvate: a new targeted antiglycolytic agent and a promise for cancer therapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Glucose; Glycolysis; Humans; Models, Biological; Neoplasms; Pyruvate Dehydrogenase Complex; Pyruvates | 2010 |
3-Bromopyruvate: targets and outcomes.
Topics: Antineoplastic Agents, Alkylating; Energy Metabolism; Glycolysis; Hexokinase; L-Lactate Dehydrogenase; Neoplasms; Pyruvate Dehydrogenase Complex; Pyruvates | 2012 |
Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug.
Topics: Antineoplastic Agents, Alkylating; Glycolysis; Humans; Metabolic Networks and Pathways; Neoplasms; Pyruvates | 2012 |
Anticancer efficacy of the metabolic blocker 3-bromopyruvate: specific molecular targeting.
Topics: Antineoplastic Agents; Apoptosis; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Molecular Targeted Therapy; Monocarboxylic Acid Transporters; Neoplasms; Pyruvates | 2013 |
The cancer cell's "power plants" as promising therapeutic targets: an overview.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Death; Cell Respiration; Cytochrome c Group; Energy Metabolism; Glycolysis; Humans; Mitochondria; Necrosis; Neoplasms; Pyruvates | 2007 |
16 other study(ies) available for bromopyruvate and Benign Neoplasms
| Article | Year |
|---|---|
Mitochondria-targeted nanoplatforms for enhanced photodynamic therapy against hypoxia tumor.
Topics: Animals; Cell Line, Tumor; Drug Synergism; Female; Humans; Indoles; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polylactic Acid-Polyglycolic Acid Copolymer; Pyruvates; Reactive Oxygen Species; Tissue Distribution; Transplantation, Heterologous; Tumor Hypoxia | 2021 |
Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro.
Topics: Electromagnetic Fields; Humans; Neoplasms; Pyruvates | 2022 |
3-Bromopyruvate-loaded bismuth sulfide nanospheres improve cancer treatment by synergizing radiotherapy with modulation of tumor metabolism.
Topics: Bismuth; Cell Line, Tumor; Nanospheres; Neoplasms; Sulfides | 2023 |
3-Bromopyruvate-Conjugated Nanoplatform-Induced Pro-Death Autophagy for Enhanced Photodynamic Therapy against Hypoxic Tumor.
Topics: Autophagy; Cell Line, Tumor; Humans; Hypoxia; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Pyruvates | 2020 |
A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells.
Topics: Adenosine Triphosphate; Alkylation; Antineoplastic Agents; Antioxidants; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; HCT116 Cells; Humans; MCF-7 Cells; Monocarboxylic Acid Transporters; Monoterpenes; Necrosis; Neoplasms; Pyruvates; RNA Interference; Signal Transduction; Symporters; Transfection | 2017 |
Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies.
Topics: Antineoplastic Agents; Citric Acid Cycle; Computer Simulation; Enzyme Inhibitors; Glycolysis; Humans; Ligands; Molecular Docking Simulation; Neoplasms; Propionates; Pyrroles; Pyruvates; Succinate Dehydrogenase | 2017 |
Enhancing anticancer effects, decreasing risks and solving practical problems facing 3-bromopyruvate in clinical oncology: 10 years of research experience.
Topics: Animals; Enzyme Inhibitors; Humans; Liposomes; Neoplasms; Polyethylene Glycols; Pyruvates; Translational Research, Biomedical | 2018 |
[Not Available].
Topics: Antineoplastic Agents; Clinical Trials as Topic; Complementary Therapies; Drug Approval; Humans; Injections, Subcutaneous; Mistletoe; Neoplasms; Plant Extracts; Pyruvates; Quackery | 2017 |
3-Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor André Goffeau.
Topics: Animals; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Fungi; Glycolysis; Hexokinase; Humans; Melanoma; Mitochondria; Multiple Myeloma; Neoplasms; Pyruvates; Pyruvic Acid | 2019 |
Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect).
Topics: Citric Acid Cycle; Glucose-6-Phosphatase; Glycolysis; Humans; Lactic Acid; Models, Biological; Neoplasms; Pyruvates; Reactive Oxygen Species | 2013 |
Combination studies of platinum(II)-based metallointercalators with buthionine-S,R-sulfoximine, 3-bromopyruvate, cisplatin or carboplatin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carboplatin; Cell Line; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Organoplatinum Compounds; Platinum; Pyruvates | 2014 |
Mitochondria: 3-bromopyruvate vs. mitochondria? A small molecule that attacks tumors by targeting their bioenergetic diversity.
Topics: Animals; Apoptosis; Energy Metabolism; Enzyme Inhibitors; Glycolysis; Hexokinase; Humans; Mitochondria; Neoplasms; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvates | 2014 |
AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; Cell Proliferation; Cell Survival; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Glycolysis; HCT116 Cells; HeLa Cells; Humans; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyruvates; Signal Transduction; Transcriptional Activation; Up-Regulation | 2016 |
Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycolysis; Hexokinase; HL-60 Cells; Humans; Lymphoma; Mitochondria; Neoplasms; Oxygen Consumption; Pyruvates | 2009 |
Flow cytometric evaluation of the effects of 3-bromopyruvate (3BP) and dichloracetate (DCA) on THP-1 cells: a multiparameter analysis.
Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dicarbethoxydihydrocollidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Neoplasms; Principal Component Analysis; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvates; Reactive Oxygen Species | 2012 |
Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.
Topics: Adenosine Triphosphate; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carrier Proteins; Cell Hypoxia; Cell Respiration; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycolysis; HL-60 Cells; Humans; Mitochondria; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyruvates | 2005 |