bromopyruvate has been researched along with Astrocytoma, Grade IV in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furugen, A; Ideno, M; Iseki, K; Ishiguro, Y; Kobayashi, M; Narumi, K | 1 |
| Azadi, J; Bow, H; Brem, H; Hutt-Cabezas, M; Hwang, L; Joshi, A; Mangraviti, A; Martin, KL; Rudek, MA; Tyler, BM; Wicks, RT; Zhang, I; Zhao, M | 1 |
| Castigli, E; Corazzi, L; Corcelli, A; Cristina Marchetti, M; Davidescu, M; Macchioni, L; Migliorati, G; Roberti, R; Scaramozzino, G; Vitale, R | 1 |
| Binaglia, L; Castigli, E; Chiasserini, D; Corazzi, L; Davidescu, M; Macchioni, L; Orvietani, PL; Petricciuolo, M; Roberti, R; Susta, F | 1 |
| Castigli, E; Coaccioli, S; Corazzi, L; Davidescu, M; Macchioni, L; Marchetti, C; Migliorati, G; Roberti, R; Sciaccaluga, M | 1 |
| Abou El-Magd, RM; Chung, SP; El Sayed, SM; Fukui, K; Kagami, S; Sakai, T; Shishido, Y; Watanabe, H | 1 |
| Chung, SP; Diem, TH; El Sayed, SM; El-Magd, RM; Fukui, K; Kagami, S; Sakai, T; Shishido, Y; Watanabe, H | 1 |
| Angelini, R; Castigli, E; Corazzi, L; Corcelli, A; Davidescu, M; Lopalco, P; Macchioni, L; Rambotti, MG; Roberti, R; Sciaccaluga, M | 1 |
| Chung, SP; El Sayed, SM; El-Magd, RM; Fukui, K; Kagami, S; Sakai, T; Shishido, Y; Tran, DH; Watanabe, H; Yorita, K | 1 |
9 other study(ies) available for bromopyruvate and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Valproate sensitizes human glioblastoma cells to 3-bromopyruvate-induced cytotoxicity.
Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Pyruvates; RNA, Messenger; Valproic Acid | 2018 |
Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
Topics: Absorbable Implants; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Dichloroacetic Acid; Drug Administration Routes; Drug Combinations; Drug Delivery Systems; Female; Glioblastoma; Glycolysis; Humans; Kaplan-Meier Estimate; Polymers; Pyruvates; Rats; Rats, Inbred F344; Temozolomide | 2015 |
The energy blockers bromopyruvate and lonidamine lead GL15 glioblastoma cells to death by different p53-dependent routes.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Energy Metabolism; Enzyme Inhibitors; Glioblastoma; Humans; Indazoles; Mitochondria; Pyruvates; Tumor Suppressor Protein p53 | 2015 |
3-Bromopyruvate treatment induces alterations of metabolic and stress-related pathways in glioblastoma cells.
Topics: Amino Acids; Carbohydrate Metabolism; Cell Line, Tumor; Glioblastoma; Glycolysis; Heat-Shock Proteins; Humans; Metabolic Networks and Pathways; Pentose Phosphate Pathway; Phosphorylation; Pyruvates; Serine | 2017 |
Mitochondrial dysfunction and effect of antiglycolytic bromopyruvic acid in GL15 glioblastoma cells.
Topics: Acetylcysteine; Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Cytochromes c; Enzyme Inhibitors; Free Radical Scavengers; Glioblastoma; Glycolysis; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Oxidation-Reduction; Proteolysis; Pyruvates; Reactive Oxygen Species | 2011 |
D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Female; Genetic Therapy; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Mice; Neoplastic Stem Cells; Oxidative Stress; Pyruvates; Rats; Rats, Sprague-Dawley; Transfection | 2012 |
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Survival; Citric Acid; D-Amino-Acid Oxidase; Electrophoresis, Polyacrylamide Gel; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Immunoblotting; Lactic Acid; Oxidative Stress; Pyruvates; Pyruvic Acid; Tetrazolium Salts; Thiazoles | 2012 |
Bromopyruvate mediates autophagy and cardiolipin degradation to monolyso-cardiolipin in GL15 glioblastoma cells.
Topics: Acridine Orange; Antineoplastic Agents, Alkylating; Autophagy; Autophagy-Related Protein 5; Blotting, Western; Cardiolipins; Cell Line, Tumor; Cell Survival; Cytoplasmic Vesicles; Glioblastoma; Humans; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Pyruvates; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Line, Tumor; Chelating Agents; Cisplatin; Citric Acid; Cytarabine; D-Amino-Acid Oxidase; Drug Resistance, Neoplasm; Energy Metabolism; Enzyme Inhibitors; Glioblastoma; Hexokinase; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Mice; Neovascularization, Pathologic; Oxidative Stress; Pyruvates | 2012 |