Compounds > bromodeoxyuridine
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bromodeoxyuridine and Colorectal Neoplasms

bromodeoxyuridine has been researched along with Colorectal Neoplasms in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.56)18.7374
1990's35 (48.61)18.2507
2000's22 (30.56)29.6817
2010's7 (9.72)24.3611
2020's4 (5.56)2.80

Authors

AuthorsStudies
Chen, H; Han, T; Jin, Z; Li, Y; Song, F; Wang, X; Xie, Z; Xiong, B; Zhang, D1
Abdullah, M; Dewi, S; Ramadhan, MF; Sadikin, M1
Chai, N; Gu, K; Hu, J; Ji, Q; Li, Q; Ren, J; Sui, H; Wang, Y; Yang, L; Zhang, B; Zhang, L; Zhou, L1
Chu, X; Cong, R; Cui, H; Gao, G; Luo, Y; Yang, M; Yu, M; Yu, W; Zhong, M1
Arvaniti, A; Foster, PA; Gilligan, LC; Gondal, A; Hewitt, AM; Morton, DG; Rahman, HP; Read, ML; Sitch, AJ; Taylor, AE1
Kobunai, T; Matsuoka, K; Takechi, T1
Arrowsmith, CH; Baiazitov, R; Cao, L; Davis, T; Dick, JE; Du, W; Frelin, C; Gallinger, S; Gibson, L; Iscove, NN; Kreso, A; Leung, C; Lima-Fernandes, E; Moon, YC; O'Brien, CA; Pedley, NM; Sydorenko, N; Szentgyorgyi, E; van Galen, P; Wang, Y1
Chung, G; Coxon, A; Jun, T; Kaplan-Lefko, P; Kendall, R; Manoukian, R; Oliner, J; Payton, M; Radinsky, R; Scully, S; Sun, JR; Van, G; Wayne, W; Yu, D; Zhang, N1
Franz, B; Hühns, M; Jaster, R; Lange, F; Linnebacher, M; Maletzki, C1
Hofer, S; Krähenbühl, S; Ludwig, C; Rätz Bravo, AE1
Dulak, A; Lazo, JS; Li, H; Tomko, RJ; Wang, P; Wang, Z; Yu, J; Zhang, L; Zhang, X; Zou, F1
Bugyik, E; Dezso, K; Döme, B; Klepetko, W; László, V; Nagy, P; Paku, S; Reiniger, L; Tímár, J; Tóvári, J1
Gu, M; Ma, S; Zhang, NQ; Zhao, L; Zheng, XY1
Kanno, J; Mikami, T; Ohkusa, T; Okayasu, I; Yamada, M; Yoshida, T1
Hirose, Y; Koshimizu, K; Matsumoto, Y; Mori, H; Murakami, A; Ohigashi, H; Sakata, K; Sayama, Y; Yoshimi, N; Zheng, Q1
Blauberger, S; Ganslmayer, M; Hahn, EG; Herold, C; Ocker, M; Schuppan, D; Zopf, S1
Ma, QY; Rowlands, BJ; Williamson, KE1
Ensser, A; Hoggarth, JH; Jones, E; Meredith, DM1
Choi, KY; Jeon, SH; Oh, JW; Park, KS1
Daniel, PT; Dörken, B; Güner, D; Hasenjäger, A; Hemmati, PG; Normand, G; Verdoodt, B; von Haefen, C; Wendt, J1
Barone, MV; Bonelli, P; Capaccio, D; Casamassimi, A; Ciccodicola, A; Colantuoni, V; Febbraro, A; Migliore, C; Pedicini, A; Peluso, G; Sabatino, L1
Desai, AB; Kinsella, TJ; Schupp, JE; Seo, Y; Yan, T; Zeng, X1
Costa, RH; Davidson, NO; Wang, IC; Yoder, HM; Yoshida, Y1
Chen, YJ; Kuo, CD; Liao, HF; Tsai, YM; Wang, GS; Yu, CC1
DiGregorio, C; Fante, R; Losi, L; Migaldi, M; Pedroni, M; Ponz de Leon, M; Roncucci, L; Trentini, GP1
DeRemer, S; Ensminger, WD; Knol, JA; Lawrence, TS; Robertson, JM; Stetson, PL; Walker, SC; Yang, Z1
Alberts, D; Earnest, D; Einspahr, J; Grogan, T; Hixson, L; Powell, M; Ritchie, J; Roe, D; Xie, T1
Risio, M1
Aickin, M; Alberts, DS; Earnest, D; Einspahr, J; Hixson, L; Powell, M; Roe, D1
Ikeda, N; Mizuno, M; Okada, H; Tomoda, J; Tsuji, T1
Schofield, PF; Wilson, MS1
Anderson, N; Crockard, A; Gilliland, R; Grimes, J; Hamilton, P; Rowlands, B; Weir, H; Williamson, K1
Arthur, K; Grimes, J; Hamilton, PW; Williamson, KE; Wilson, RH1
Halliday, MI; Hamilton, PW; Rowlands, BJ; Williamson, KE1
Hakamada, K; Matsumoto, M; Suzuki, H; Tahara, E; Taniyama, K; Toyama, K1
Di Gregorio, C; Fante, R; Pedroni, M; Ponz de Leon, M; Roncucci, L1
Daidoh, T; Shioaki, Y; Takahashi, T; Taniguchi, H1
Crockard, A; Halliday, I; Hamilton, P; Maxwell, P; Rowlands, B; Ruddell, J; Varma, M; Williamson, K1
Rew, DA; Sawtell, RM; Stradling, RN; Wilson, GD1
Kinsella, TJ1
Iriyama, K; Kitagawa, T; Matsumoto, K; Suzuki, H1
Kilias, D; Macrae, FA; Sharpe, K; Young, GP1
Bostick, RM; Elmer, P; Fosdick, L; Grambsch, P; Lillemoe, TJ; Overn, P; Potter, JD; Wood, JR1
Ducrotté, P; Hemet, J; Laquerriere, A; Menard, JF; Michel, P; Paillot, B; Paresy, M; Peillon, C; Scotte, M1
Hood, CJ; Parham, DM1
Bertram, JF; Christophi, C; Kuruppu, D; O'Brien, PE1
Esumi, H; Fukushima, S; Otori, K; Sugiyama, K1
Meijers, M; Rijken, PJ; Tijburg, LB; Timmer, WG; van Benschop, IM; van de Kooij, AJ; Wiseman, SA1
Ducrotté, P; Hellot, MF; Hemet, J; Lepessot, F; Michel, P; Paillot, B; Paresy, M; Peillon, C; Scotte, M1
Burt, RW; Corle, DK; Freedman, LS; Kulldorff, M; Lanza, E; Lawson, M; Mateski, DJ; McShane, LM; Moler, J; O'Brien, B; Purewal, M; Schatzkin, A; Wargovich, MJ; Woods, C1
Anti, M; Armuzzi, A; Coco, C; Covino, M; Gasbarrini, A; Gasbarrini, G; Iascone, E; Lorenzetti, R; Morini, S; Paolucci, M; Pignataro, G; Vecchio, F1
Smith, AM; Watson, SA1
Brown, WA; Malcontenti-Wilson, C; O'Brien, PE; Skinner, SA; Vogiagis, D1
Hellot, MF; Hemet, J; Le Pessot, F; Lemoine, F; Michel, P; Paillot, B; Paresy, M; Peillon, C; Scotte, M1
Itonaga, K; Ochi, T; Shimizu, N1
Cho, M; Choi, YH; Lee, WJ; Oh, EJ; Park, JH; Yoo, MA1
Ahn, Y; Choi, KY; Kim, HI; Kim, JA; Oh, JW; Oh, SY; Park, KS1
Laing, JH; Rew, DA; Wilson, GD1
Bormioli, ML; Di Gregorio, C; Fante, R; Losi, L; Pedroni, M; Petocchi, B; Ponz de Leon, M; Roncucci, L; Sassatelli, R; Scalmati, A1
Rozen, P1
Davis, MA; Ensminger, WD; Lawrence, TS; Maybaum, J; McKeever, PE; Mukhopadhyay, SK; Normolle, DP; Stetson, PL1
Arveux, P; Hammann, A; Martin, M1
Takegawa, S1
Burton, EC; Dusenbury, CE; Ensminger, WD; Jing, HW; Maybaum, J; Shelton, DA; Stetson, PL1
Armocida, C; Bellentani, S; Biasco, G; Brandi, G; Paganelli, GM; Ponz de Leon, M; Saccoccio, G; Santucci, R1
Bokhari, J; Hyams, D; Khan, S; Raza, A; Sheikh, Y; Yousuf, N1
Bertone, A; Candelaresi, G; Coverlizza, S; Lipkin, M; Risio, M; Rossini, FP1
Kosaka, T; Miwa, K; Miyazaki, I; Ooyama, S; Takegawa, S; Yamaguchi, A; Yonemura, Y1
Burton, EC; Ensminger, WD; Hafner, MS; Maybaum, J; Rogers, CE; Stetson, PL1
Inoue, YK; Nishibe, Y1
Khan, S; Mittleman, A; Petrelli, N; Raza, A1
Kitagawa, T; Matsumoto, K; Sugenoya, Y; Suzuki, H1

Reviews

2 review(s) available for bromodeoxyuridine and Colorectal Neoplasms

ArticleYear
Methodological aspects of using immunohistochemical cell proliferation biomarkers in colorectal carcinoma chemoprevention.
    Journal of cellular biochemistry. Supplement, 1994, Volume: 19

    Topics: Amino Acid Sequence; Antibodies; Anticarcinogenic Agents; Antigens, Neoplasm; Biomarkers, Tumor; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Humans; Immunohistochemistry; Ki-67 Antigen; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Proliferating Cell Nuclear Antigen

1994
An evaluation of rectal epithelial proliferation measurement as biomarker of risk for colorectal neoplasia and response in intervention studies.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1992, Volume: 1, Issue:3

    Topics: Biomarkers; Biopsy; Bromodeoxyuridine; Colitis, Ulcerative; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Humans; Hyperplasia; Immunohistochemistry; Precancerous Conditions; Predictive Value of Tests; Rectum; Risk Factors; Sigmoidoscopy

1992

Trials

2 trial(s) available for bromodeoxyuridine and Colorectal Neoplasms

ArticleYear
Validation of proliferation indices as surrogate endpoint biomarkers.
    Journal of cellular biochemistry. Supplement, 1994, Volume: 19

    Topics: Adenoma; Adult; Autoradiography; Biomarkers; Biopsy; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Humans; Intestinal Mucosa; Mitotic Index; Quality Control; Rectum; Reproducibility of Results; Sigmoidoscopy; Thymidine; Tritium

1994
Pre-operative kinetic parameter determination of colorectal adenocarcinomas. Prognostic significance.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biopsy; Bromodeoxyuridine; Colon; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Ploidies; Predictive Value of Tests; Prognosis; Proportional Hazards Models; S Phase

2000

Other Studies

68 other study(ies) available for bromodeoxyuridine and Colorectal Neoplasms

ArticleYear
DDR1 promotes LoVo cell proliferation by regulating energy metabolism.
    Acta biochimica et biophysica Sinica, 2022, May-25, Volume: 54, Issue:5

    Topics: Bromodeoxyuridine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Diamide; Discoidin Domain Receptor 1; Discoidin Domain Receptors; Energy Metabolism; Humans; Lactic Acid; Protein Isoforms; Pyruvate Kinase; Receptor Protein-Tyrosine Kinases; Sincalide

2022
The Effect of Avidin on Viability and Proliferation of Colorectal Cancer Cells HT-29.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Jun-01, Volume: 23, Issue:6

    Topics: Avidin; Bromodeoxyuridine; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; HT29 Cells; Humans; RNA, Messenger

2022
YYFZBJS ameliorates colorectal cancer progression in Apc
    Cell communication and signaling : CCS, 2020, 07-16, Volume: 18, Issue:1

    Topics: Adenomatous Polyposis Coli Protein; Animals; Bacteroides fragilis; Bromodeoxyuridine; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Drugs, Chinese Herbal; Gastrointestinal Microbiome; HCT116 Cells; Humans; Immunity; Ki-67 Antigen; Leukocytes, Mononuclear; Lymph Nodes; Mice; Mice, Inbred C57BL; Mucous Membrane; Proliferating Cell Nuclear Antigen; RNA, Messenger; Spleen; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory

2020
GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression.
    Cancer science, 2021, Volume: 112, Issue:5

    Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colon; Colorectal Neoplasms; DNA; G1 Phase; Gene Knockdown Techniques; Hedgehog Proteins; Heterografts; Histone Deacetylase 2; HT29 Cells; Humans; Intestinal Mucosa; Mice; Mice, Nude; Morpholines; Neoplasm Proteins; Neoplasm Transplantation; Nuclear Proteins; Patched-1 Receptor; Purines; Pyridines; Pyrimidines; Receptors, G-Protein-Coupled; RNA, Messenger; Zinc Finger Protein Gli2

2021
Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER.
    The Journal of clinical endocrinology and metabolism, 2017, 12-01, Volume: 102, Issue:12

    Topics: Activation, Metabolic; Animals; Antimetabolites; Bromodeoxyuridine; Cell Line; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Estrogens; Female; Humans; Male; Mice; Mice, Nude; Middle Aged; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Steryl-Sulfatase; Xenograft Model Antitumor Assays

2017
ChIP-seq Analysis to Explore DNA Replication Profile in Trifluridine-treated Human Colorectal Cancer Cells
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Antimetabolites, Antineoplastic; Bromodeoxyuridine; Colorectal Neoplasms; DNA Replication; HCT116 Cells; Humans; Sequence Analysis, DNA; Trifluridine

2019
Self-renewal as a therapeutic target in human colorectal cancer.
    Nature medicine, 2014, Volume: 20, Issue:1

    Topics: Animals; Blotting, Western; Bromodeoxyuridine; Cell Line, Tumor; Colorectal Neoplasms; Flow Cytometry; Genetic Vectors; Heterocyclic Compounds, 2-Ring; Humans; Luciferases; Mice, Inbred NOD; Mice, SCID; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Polycomb Repressive Complex 1; RNA Interference; RNA, Small Interfering; Thiazoles

2014
Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method.
    Laboratory investigation; a journal of technical methods and pathology, 2014, Volume: 94, Issue:11

    Topics: Animals; Antibodies, Neutralizing; Bromodeoxyuridine; Cell Proliferation; Colorectal Neoplasms; Endothelial Cells; Female; Flow Cytometry; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice, Nude; Neoplasms, Experimental; Receptor, TIE-2; Recombinant Fusion Proteins; Xenograft Model Antitumor Assays

2014
Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
    BioMed research international, 2014, Volume: 2014

    Topics: Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Death; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Inhibitory Concentration 50; Male; Molecular Targeted Therapy; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries

2014
Fatal drug-drug interaction of brivudine and capecitabine.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Aged, 80 and over; Antimetabolites, Antineoplastic; Antiviral Agents; Bromodeoxyuridine; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fatal Outcome; Female; Fluorouracil; Herpes Zoster; Humans; Switzerland

2009
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.
    Cancer research, 2009, Oct-15, Volume: 69, Issue:20

    Topics: Apoptosis; Bromodeoxyuridine; cdc25 Phosphatases; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; DNA Damage; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Luciferases; MicroRNAs; Mitotic Index; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering

2009
Lack of angiogenesis in experimental brain metastases.
    Journal of neuropathology and experimental neurology, 2011, Volume: 70, Issue:11

    Topics: Angiopoietin-1; Animals; Brain Neoplasms; Breast Neoplasms; Bromodeoxyuridine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; DNA-Binding Proteins; Electron Microscope Tomography; Female; Glial Fibrillary Acidic Protein; Humans; Keratins; Lamins; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Quinolines; Receptor, Platelet-Derived Growth Factor beta; Thiazoles; Vascular Endothelial Growth Factor A

2011
Potent anticancer effects of lentivirus encoding a Drosophila melanogaster deoxyribonucleoside kinase mutant combined with brivudine.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:5

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Bromodeoxyuridine; Cell Proliferation; Colorectal Neoplasms; Combined Modality Therapy; Drosophila melanogaster; Female; Flow Cytometry; Genetic Therapy; Genetic Vectors; Humans; Lentivirus; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Phosphotransferases (Alcohol Group Acceptor); Prohibitins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Stomach Neoplasms; Tumor Cells, Cultured

2012
Dysplasia and carcinoma development in a repeated dextran sulfate sodium-induced colitis model.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:10

    Topics: Adenocarcinoma; Animals; Bromodeoxyuridine; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Indicators and Reagents; Mice; Mice, Inbred CBA; Radiation-Sensitizing Agents; Rectum

2002
Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Anticarcinogenic Agents; Apoptosis; Bromodeoxyuridine; Cell Division; Chemoprevention; Colorectal Neoplasms; DNA; Humans; Tumor Cells, Cultured

2002
Overadditive anti-proliferative and pro-apoptotic effects of a combination therapy on colorectal carcinoma cells.
    International journal of oncology, 2003, Volume: 23, Issue:3

    Topics: Alitretinoin; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bromodeoxyuridine; Carcinoma; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Separation; Ciprofloxacin; Colonic Neoplasms; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; Indicators and Reagents; Kinetics; Prognosis; Propidium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Time Factors; Tretinoin

2003
Ethylene diamine tetraacetic acid-induced colonic crypt cell proliferation in rats.
    World journal of gastroenterology, 2004, Jan-15, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Bromodeoxyuridine; Cell Division; Chelating Agents; Colon; Colorectal Neoplasms; Disease Models, Animal; Edetic Acid; Male; Rats; Rats, Wistar

2004
Functional expression of thymidine kinase in human leukaemic and colorectal cells, delivered as EGFP fusion protein by herpesvirus saimiri-based vector.
    Cancer gene therapy, 2004, Volume: 11, Issue:9

    Topics: Animals; Antiviral Agents; Aotidae; Base Sequence; Bromodeoxyuridine; Cells, Cultured; Colorectal Neoplasms; Ganciclovir; Genetic Vectors; Green Fluorescent Proteins; Humans; Jurkat Cells; K562 Cells; Kidney; Leukemia; Molecular Sequence Data; Pancreatic Neoplasms; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Transfection

2004
p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells.
    Experimental & molecular medicine, 2004, Dec-31, Volume: 36, Issue:6

    Topics: Bromodeoxyuridine; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Protein Kinase Inhibitors; Signal Transduction; Zinc

2004
Loss of p21 disrupts p14 ARF-induced G1 cell cycle arrest but augments p14 ARF-induced apoptosis in human carcinoma cells.
    Oncogene, 2005, Jun-09, Volume: 24, Issue:25

    Topics: Adenoviridae; Apoptosis; Bromodeoxyuridine; Carcinoma; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase; Gene Deletion; Genetic Vectors; Humans; Kidney; Tumor Suppressor Protein p14ARF

2005
A novel peroxisome proliferator-activated receptor gamma isoform with dominant negative activity generated by alternative splicing.
    The Journal of biological chemistry, 2005, Jul-15, Volume: 280, Issue:28

    Topics: Alternative Splicing; Animals; Blotting, Western; Bromodeoxyuridine; Caco-2 Cells; Cell Nucleus; Cell Proliferation; Chromans; Colorectal Neoplasms; COS Cells; DNA, Complementary; Exons; Genes, Dominant; Genes, Reporter; Genetic Vectors; Humans; In Vitro Techniques; Introns; Ligands; Luciferases; Mice; Microscopy, Fluorescence; Models, Genetic; NIH 3T3 Cells; Open Reading Frames; PPAR gamma; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazolidinediones; Transcriptional Activation; Transfection; Troglitazone

2005
Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:4

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cell Survival; Cellular Senescence; Colorectal Neoplasms; G1 Phase; Humans; Hydroxylamines; Idoxuridine; Kinetics; Radiation-Sensitizing Agents

2006
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.
    Gastroenterology, 2007, Volume: 132, Issue:4

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azoxymethane; Biomarkers, Tumor; Bromodeoxyuridine; Carcinogens; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin A; Cyclin A2; Cyclin B; Cyclin B1; Dextran Sulfate; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms, Experimental; Polymerase Chain Reaction; Proteins; Repressor Proteins; RNA, Neoplasm; RNA, Small Interfering; RNA, Untranslated; Survivin; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein

2007
Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells.
    Anti-cancer drugs, 2008, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Animals; Anoikis; Antimetabolites; Antineoplastic Agents; Blotting, Western; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Bromodeoxyuridine; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Data Interpretation, Statistical; Enzyme Activation; Flow Cytometry; JNK Mitogen-Activated Protein Kinases; Mice; Monocytes

2008
Argyrophilic nucleolar organizer regions and bromodeoxyuridine and 3[H]-thymidine labelling indices in colorectal cancer.
    Cell proliferation, 1995, Volume: 28, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Humans; Kinetics; Male; Middle Aged; Nucleolus Organizer Region; Silver Staining; Thymidine; Tritium

1995
Incorporation of 5-bromo-2'-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion.
    Cancer research, 1995, Sep-01, Volume: 55, Issue:17

    Topics: Adult; Aged; Bromodeoxyuridine; Colorectal Neoplasms; DNA; DNA, Neoplasm; Female; Follow-Up Studies; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms; Male; Middle Aged

1995
Comparison of proliferating cell nuclear antigen versus the more standard measures of rectal mucosal proliferation rates in subjects with a history of colorectal cancer and normal age-matched controls.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:4

    Topics: Adult; Aged; Autoradiography; Bromodeoxyuridine; Case-Control Studies; Cell Division; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Proliferating Cell Nuclear Antigen; Thymidine

1995
Immunohistochemical analysis of epithelial cell proliferation in normal-appearing rectal mucosa of patients with colorectal adenoma and cancer using an in vitro labeling method with bromodeoxyuridine.
    Acta medica Okayama, 1994, Volume: 48, Issue:5

    Topics: Adenoma; Adult; Aged; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Middle Aged; Rectum

1994
Markers to study human colonic cell proliferation.
    Gut, 1995, Volume: 36, Issue:1

    Topics: Bromodeoxyuridine; Cell Division; Colon; Colorectal Neoplasms; Humans; Proliferating Cell Nuclear Antigen

1995
Hydrochloric acid denaturation of colorectal tumour tissue infiltrated with bromodeoxyuridine.
    Cytometry, 1994, Feb-01, Volume: 15, Issue:2

    Topics: Antibodies, Monoclonal; Artifacts; Bromodeoxyuridine; Cell Differentiation; Colorectal Neoplasms; DNA Replication; DNA, Neoplasm; DNA, Single-Stranded; Flow Cytometry; Frozen Sections; Humans; Hydrochloric Acid; Immunohistochemistry; Nucleic Acid Denaturation; Pepsin A; Reproducibility of Results

1994
Three-dimensional computerised analysis of epithelial cell proliferation in the gastrointestinal tract.
    British journal of cancer, 1994, Volume: 69, Issue:6

    Topics: Bromodeoxyuridine; Cell Division; Colon; Colorectal Neoplasms; Computer Simulation; Epithelium; Humans; Intestinal Mucosa; Mitotic Index; Reference Values; Risk Factors; Software

1994
Are bioavailable glutamine and sensitivity to hydrochloric acid DNA denaturation important colorectal tumour characteristics?
    Biochemical Society transactions, 1994, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Adenoma, Villous; Bromodeoxyuridine; Cell Differentiation; Colorectal Neoplasms; DNA, Neoplasm; Glutamine; Humans; Tumor Cells, Cultured

1994
Relationships between nodal status and cell kinetics, DNA ploidy pattern and histopathology of the deeply infiltrating sites in colorectal adenocarcinoma.
    Acta pathologica japonica, 1993, Volume: 43, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Differentiation; Colorectal Neoplasms; DNA, Neoplasm; Female; Humans; Kinetics; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Ploidies; S Phase

1993
Cell kinetic evaluation of human colonic aberrant crypts. (Colorectal Cancer Study Group of the University of Modena and the Health Care District 16, Modena, Italy).
    Cancer research, 1993, Aug-15, Volume: 53, Issue:16

    Topics: Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Division; Colon; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; S Phase

1993
Blood supply and drug delivery to primary and secondary human liver cancers studied with in vivo bromodeoxyuridine labeling.
    Cancer, 1993, Jan-01, Volume: 71, Issue:1

    Topics: Bromodeoxyuridine; Carcinoma, Hepatocellular; Colorectal Neoplasms; Hepatic Artery; Humans; Injections, Intra-Arterial; Injections, Intravenous; Iodized Oil; Liver Neoplasms; Portal Vein

1993
In vitro BrdUrd incorporation of colorectal tumour tissue.
    Cell proliferation, 1993, Volume: 26, Issue:2

    Topics: Bromodeoxyuridine; Cell Separation; Cell Survival; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Humans

1993
Pan cycle expression of proliferating cell nuclear antigen in human colorectal cancer and its proliferative correlations.
    Cytometry, 1995, Sep-15, Volume: 22, Issue:3

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Colorectal Neoplasms; Flow Cytometry; Humans; Proliferating Cell Nuclear Antigen; Reproducibility of Results

1995
Correspondence re: J.A. Knol et al., Incorporation of 5-bromo-2-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion. Cancer Res., 55: 3687-3691, 1995.
    Cancer research, 1996, Jun-01, Volume: 56, Issue:11

    Topics: Bromodeoxyuridine; Colorectal Neoplasms; DNA, Neoplasm; Humans; Idoxuridine; Liver; Liver Neoplasms; Radiation-Sensitizing Agents

1996
Prognostic significance of the bromodeoxyuridine labeling index in primary colorectal carcinoma.
    Surgery today, 1997, Volume: 27, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal; Bromodeoxyuridine; Colorectal Neoplasms; DNA, Neoplasm; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Male; Middle Aged; Prognosis; S Phase; Survival Analysis

1997
The effect of incubation of rectal biopsies on measures of proliferation using proliferating cell nuclear antigen in comparison with 5-bromo-2-deoxyuridine.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Biopsy; Bromodeoxyuridine; Colorectal Neoplasms; Epithelial Cells; Female; Humans; Immunohistochemistry; Male; Middle Aged; Proliferating Cell Nuclear Antigen; Rectum

1997
Methodological findings and considerations in measuring colorectal epithelial cell proliferation in humans.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:11

    Topics: Analysis of Variance; Biopsy; Bromodeoxyuridine; Cell Division; Colon; Colorectal Neoplasms; Epithelial Cells; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Proliferating Cell Nuclear Antigen; Rectum; S Phase

1997
Comparison between endoscopic and surgical sampling for the measurement of potential doubling time in colorectal cancer.
    Cytometry, 1997, Nov-01, Volume: 29, Issue:3

    Topics: Aneuploidy; Biopsy; Bromodeoxyuridine; Colonoscopy; Colorectal Neoplasms; Humans; Kinetics; Preoperative Care

1997
A simple method of tumour culture.
    Pathology, research and practice, 1998, Volume: 194, Issue:3

    Topics: Adenocarcinoma; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Culture Techniques; Female; Humans; Stromal Cells; Tumor Cells, Cultured

1998
Tamoxifen inhibits colorectal cancer metastases in the liver: a study in a murine model.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:5

    Topics: Animals; Bromodeoxyuridine; Carcinoma; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Liver; Liver Neoplasms; Mice; Mice, Inbred CBA; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Tamoxifen; Tumor Cells, Cultured

1998
Expression of the cyclin D1 gene in rat colorectal aberrant crypt foci and tumors induced by azoxymethane.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Adenocarcinoma; Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Cell Nucleus; Colorectal Neoplasms; Cyclin D1; Cytoplasm; Gene Expression; Hyperplasia; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Time Factors

1999
Effect of vegetable and carotenoid consumption on aberrant crypt multiplicity, a surrogate end-point marker for colorectal cancer in azoxymethane-induced rats.
    Carcinogenesis, 1999, Volume: 20, Issue:12

    Topics: Animals; Azoxymethane; Biomarkers, Tumor; Body Weight; Bromodeoxyuridine; Carcinogens; Carotenoids; Colorectal Neoplasms; Food; Rats; Vegetables

1999
Measuring cell proliferation in the rectal mucosa. comparing bromodeoxyuridine (BrdU) and proliferating cell nuclear antigen (PCNA) assays.
    Journal of clinical epidemiology, 2000, Volume: 53, Issue:8

    Topics: Adenoma; Adult; Analysis of Variance; Biopsy; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Proliferating Cell Nuclear Antigen; Rectum

2000
Severe imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomas.
    Gut, 2001, Volume: 48, Issue:2

    Topics: Adenoma; Adult; Aged; Analysis of Variance; Apoptosis; Biopsy; Bromodeoxyuridine; Case-Control Studies; Cell Division; Colorectal Neoplasms; Female; Humans; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Middle Aged; Statistics, Nonparametric

2001
Hypergastrinemia promotes adenoma progression in the APC(Min-/+) mouse model of familial adenomatous polyposis.
    Cancer research, 2001, Jan-15, Volume: 61, Issue:2

    Topics: Adenoma; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Bromodeoxyuridine; Cancer Vaccines; Colorectal Neoplasms; Cytoskeletal Proteins; Diphtheria Toxoid; Disease Models, Animal; Disease Progression; Female; Gastrins; Gene Expression Regulation; Heterozygote; Immunization; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Omeprazole; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Survival Rate

2001
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation.
    Gut, 2001, Volume: 48, Issue:5

    Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Staining and Labeling

2001
Cell proliferation in colorectal adenocarcinomas: comparison between Ki-67 immunostaining and bromodeoxyuridine uptake detected by immunohistochemistry and flow cytometry.
    Pathology, research and practice, 2001, Volume: 197, Issue:6

    Topics: Adenocarcinoma; Aged; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Flow Cytometry; Humans; Immunohistochemistry; Ki-67 Antigen; Lymph Nodes; Lymphatic Metastasis; Male; Ploidies

2001
Replication timing of amplified genetic regions relates to intranuclear localization but not to genetic activity or G/R band.
    Experimental cell research, 2001, Aug-15, Volume: 268, Issue:2

    Topics: Bromodeoxyuridine; Cell Compartmentation; Cell Nucleus; Chromatin; Chromosome Banding; Chromosomes, Human; Colorectal Neoplasms; DNA Replication; DNA, Neoplasm; Gene Amplification; Gene Silencing; Humans; S Phase; Staining and Labeling; Transcription, Genetic; Tumor Cells, Cultured

2001
The caudal-related homeodomain protein CDX1 activates proliferating cell nuclear antigen expression in hepatocellular and colorectal carcinoma cells.
    International journal of oncology, 2002, Volume: 20, Issue:1

    Topics: Amino Acid Sequence; Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; CDX2 Transcription Factor; Colorectal Neoplasms; DNA Primers; Drosophila; Electrophoretic Mobility Shift Assay; Glutathione Transferase; Homeodomain Proteins; Humans; Liver Neoplasms; Luciferases; Mice; Molecular Sequence Data; Proliferating Cell Nuclear Antigen; Recombinant Fusion Proteins; RNA; Sequence Homology, Amino Acid; Trans-Activators

2002
Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells.
    Cancer letters, 2002, May-28, Volume: 179, Issue:2

    Topics: Blotting, Western; Bromodeoxyuridine; Cell Division; Cell Nucleus; Chromans; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; HT29 Cells; Humans; Luciferases; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tumor Cells, Cultured

2002
Cell kinetics of human solid tumours.
    BJR supplement, 1992, Volume: 24

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Colorectal Neoplasms; Flow Cytometry; Humans; Melanoma; Prognosis; Prospective Studies; Skin Neoplasms

1992
Cell kinetics evaluation of colorectal tumors after in vivo administration of bromodeoxyuridine.
    International journal of cancer, 1992, Dec-02, Volume: 52, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Humans; Immunohistochemistry; Male; Middle Aged; Oncogene Protein p21(ras); Thymidine; Tritium; Tumor Cells, Cultured

1992
The potential superiority of bromodeoxyuridine to iododeoxyuridine as a radiation sensitizer in the treatment of colorectal cancer.
    Cancer research, 1992, Jul-01, Volume: 52, Issue:13

    Topics: Animals; Bromodeoxyuridine; Colorectal Neoplasms; DNA; DNA Damage; Female; Humans; Idoxuridine; Infant; Mice; Neoplasm Transplantation; Radiation-Sensitizing Agents; Transplantation, Heterologous

1992
Effect of gut-associated lymphoid tissue on cellular proliferation in proximal and distal colon of the rat.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:7

    Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Division; Colon; Colorectal Neoplasms; Lymphoid Tissue; Male; Peyer's Patches; Rats; Rats, Inbred Strains; Risk Factors

1992
[Correlation of DNA index and BrdU labeling index with clinicopathological factors in colorectal carcinoma].
    Nihon Geka Gakkai zasshi, 1992, Volume: 93, Issue:6

    Topics: Adenocarcinoma; Bromodeoxyuridine; Chi-Square Distribution; Colorectal Neoplasms; DNA, Neoplasm; Flow Cytometry; Humans; Lymphatic Metastasis; Neoplasm Staging; Ploidies

1992
Divergent patterns of incorporation of bromodeoxyuridine and iododeoxyuridine in human colorectal tumor cell lines.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Floxuridine; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Idoxuridine; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1991
Correlation between bromodeoxyuridine labelling and ornithine decarboxylase levels in normal rectal mucosa of patients with colorectal adenoma.
    Cancer letters, 1991, Volume: 59, Issue:3

    Topics: Adenoma; Adult; Aged; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Ornithine Decarboxylase

1991
Cell cycle parameters and DNA ploidy in colorectal carcinomas.
    The Journal of surgical research, 1991, Volume: 51, Issue:6

    Topics: Adenocarcinoma; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Cycle; Colorectal Neoplasms; DNA; Humans; Idoxuridine; Pilot Projects; Ploidies; S Phase; Time Factors

1991
Correlations between rectal mucosa cell proliferation and the clinical and pathological features of nonfamilial neoplasia of the large intestine.
    Cancer research, 1991, Apr-01, Volume: 51, Issue:7

    Topics: Adenocarcinoma; Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Pathology; Rectum

1991
[Metastasis and its relation to cell kinetics in human colorectal cancers].
    Nihon Geka Gakkai zasshi, 1990, Volume: 91, Issue:6

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Colorectal Neoplasms; Flow Cytometry; Humans; Liver Neoplasms; Lymphatic Metastasis

1990
Response of human HT-29 colorectal tumor cells to extended exposure to bromodeoxyuridine.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:1

    Topics: Bromodeoxyuridine; Cell Line; Colorectal Neoplasms; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Time Factors; Tumor Cells, Cultured

1989
Isolation of Inoue-Melnick virus from human colorectal carcinoma cell lines.
    Journal of medical virology, 1989, Volume: 29, Issue:3

    Topics: Bromodeoxyuridine; Colorectal Neoplasms; Humans; Tumor Cells, Cultured; Viruses

1989
In vivo determinations of labelling index of metastatic colorectal carcinoma and normal colonic mucosa using intravenous infusions of bromodeoxyuridine.
    Journal of surgical oncology, 1988, Volume: 39, Issue:2

    Topics: Bromodeoxyuridine; Carcinoma; Cell Cycle; Colon; Colorectal Neoplasms; DNA; Humans; Infusions, Intravenous; Intestinal Mucosa; Neoplasm Metastasis

1988
[Flow cytometric determination of S phase fractions of colorectal carcinomas using: preliminary report anti-bromodeoxyuridine monoclonal antibody].
    Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal; Bromodeoxyuridine; Colorectal Neoplasms; DNA, Neoplasm; Female; Flow Cytometry; Humans; Interphase; Male; Middle Aged

1988