bromodeoxyuridine has been researched along with Colonic Neoplasms in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (5.77) | 18.7374 |
| 1990's | 40 (38.46) | 18.2507 |
| 2000's | 50 (48.08) | 29.6817 |
| 2010's | 4 (3.85) | 24.3611 |
| 2020's | 4 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ao, J; Huang, Y; Li, S; Li, T; Wang, C; Wang, Y; Wu, Z; Yang, C; Zhou, Y | 1 |
| Lau, CB; Leung, PC; Wong, CK; Yang, H; Yue, GG; Zhang, YJ | 1 |
| Abe, S; Emoto, S; Ishihara, S; Murono, K; Nagai, Y; Nozawa, H; Sasaki, K; Sonoda, H; Taira, T; Yokoyama, Y | 1 |
| Fabianova, D; Kello, M; Keselakova, A; Martinkova, M; Nosalova, N; Pilatova, MB | 1 |
| Fujisawa, M; Fushimi, S; Hiraoka, S; Itakura, J; Ito, T; Matsukawa, A; Ohkura, T; Okada, H; Takahashi, S; Yamamoto, K; Yoshimura, T | 1 |
| Chatterjee, M; Ghosh, B; Rajkumar, M; Rana, A; Samanta, S | 1 |
| Bouchot, A; Bouyer, F; Cathelin, D; Chauffert, B; Droin, N; Favier, L; Ghiringhelli, F; Guilly, MN; Kroemer, G; Martin, F; Puig, PE; Solary, E | 1 |
| Mełeń-Mucha, G; Motylewska, E | 1 |
| Arihara, K; Asano, T; Ishikawa, S; Itoh, M; Nozawa, Y; Takenoshita, S | 1 |
| Piplani, H; Sanyal, S; Tanwar, L | 1 |
| Engel, A; Knobloch, T; Langer, K; Löw, K; von Briesen, H; Wagner, S; Wiehe, A | 1 |
| Baker, J; Banu, NA; Buda, A; Daly, RS; Moorghen, M; Pignatelli, M | 1 |
| Cutress, RI; Mullee, MA; Rew, DA | 1 |
| Ma, QY; Rowlands, BJ; Williamson, KE | 1 |
| Beryt, M; Boyer, CR; Karjian, PL; Neuteboom, ST; Pegram, M; Shepard, HM; Wahl, GM | 1 |
| Downes, CS; Mahmud, N; McGlynn, AP; McKelvey-Martin, VJ; McKerr, G; McNulty, H; Mullan, F; O'Reilly, S; Scott, J; Strain, JJ; Wasson, GR; Weir, DG | 1 |
| Cernaianu, G; Cetto, M; Falk, W; Geissler, EK; Guba, M; Jauch, KW; Köhl, G; Kunz-Schughart, LA; Steinbauer, M | 1 |
| Asamoto, M; Ogawa, K; Shirai, T; Takeshita, F | 1 |
| Angulo, JF; Biard, DS; Créminon, C; Despras, E; Harper, F; Miccoli, L; Pichard, E | 1 |
| Kawamori, T; Sugimura, T; Uchiya, N; Wakabayashi, K | 1 |
| Dellinger, RW; Karjian, PL; Neuteboom, ST | 1 |
| Blauberger, S; Ganslmayer, M; Hahn, EG; Herold, C; Ocker, M; Schuppan, D; Zopf, S | 1 |
| Auditore-Hargreaves, K; Axworthy, D; Dearstyne, E; Graves, SS; Gray, D; Jones, HM; Lin, Y; Pantalias, A; Sanderson, J; Schultz, J; Zuo, Y | 1 |
| Aoki, K; Horiike, S; Oshima, M; Taketo, MM; Tamai, Y | 1 |
| Jardine, LJ | 1 |
| Doi, K; Fukushima, S; Mitsuhashi, M; Moku, M; Morimura, K; Salim, EI; Shen, J; Wanibuchi, H; Wei, M | 1 |
| Balcerczak, E; Lipa, S; Melen-Mucha, G; Mirowski, M; Mucha, S; Panczyk, M | 1 |
| Bussink, J; Heerschap, A; Lok, J; Punt, CJ; van Der Kogel, AJ; van Laarhoven, HW | 1 |
| Ji, GE; Oh, DK; You, HJ | 1 |
| Blandizzi, C; Breschi, MC; Colucci, R; Del Tacca, M; Tanini, M; Vassalle, C | 1 |
| Hellerstein, MK; Killion, S; Kim, SJ; Turner, S | 1 |
| Isobe, M; Kato, N; Komatsu, S; Yanaka, N | 1 |
| Barnard, GF; Do, K | 1 |
| Congiatu, C; Davies, G; Jiang, WG; Mason, MD; McGuigan, C | 1 |
| Fukami, H; Hirata, A; Sakai, H; Tatematsu, M; Tsukamoto, T | 1 |
| Braun, T; Carvalho, G; Castedo, M; Coquelle, A; Kroemer, G; Métivier, D; Mouhamad, S; Pequignot, MO; Vivet, S | 1 |
| Bernatchez, G; Carrier, JC; Giroux, V; Lemay, F; Robitaille, Y | 1 |
| Browne, W; Johnson, JB; Noguchi, PD | 1 |
| Davis, MA; Lawrence, TS; Normolle, DP | 1 |
| Burton, J; Fellows, IW; Gee, JM; Johnson, IT; Kennedy, HJ; Matthew, JA; Pell, JD; Prior, A | 1 |
| Hara, A; Hirose, Y; Kawamori, T; Mori, H; Nakamura, Y; Ohnishi, M; Satoh, K; Tanaka, T | 1 |
| Mori, H; Tanaka, T; Wang, A; Yoshimi, N | 1 |
| Bird, RP; Sutherland, LA | 1 |
| Esumi, H; Minamoto, T; Onda, M; Yamashita, N | 1 |
| Burgess, AC; Lawrence, TS; Normolle, DP; Trent, JM; Wilt, SR | 1 |
| Bird, RP; Magnuson, BA; Shirtliff, N | 1 |
| Hayashi, S; Kobayashi, T; Negita, M; Sato, E; Takagi, H; Uchida, K; Yokoyama, I | 1 |
| Cheyer, C; O'Riordan, MA; Pretlow, TP | 1 |
| Davis, MA; Ensminger, WD; Lawrence, TS; Maybaum, J; Stetson, PL | 2 |
| Takahashi, N | 1 |
| Cass, L; Dubin, JA; Fujita, K; Glober, GA; Hittelman, WN; Konishi, H; Lee, JJ; Spaulding, D; Steinbach, G; Terry, NH | 1 |
| Hara, A; Kawamori, T; Makita, H; Mori, H; Ohnishi, M; Satoh, K; Tanaka, T | 1 |
| Chang, EY; Davis, MA; Ensminger, WD; Lawrence, TS; Stetson, PL | 1 |
| Ensminger, WD; Kessler, ML; Lawrence, TS; Marx, MV; McGinn, CJ; Robertson, JM; Walker, S | 1 |
| Wilson, GD | 1 |
| Dohi, K; Ito, A; Katoh, O; Masaoka, Y; Watanabe, H | 1 |
| Chang, D; Chen, F; Ljungman, M; McKay, BC; Zhang, F | 1 |
| Ducrotté, P; Hemet, J; Lepessot, F; Mauillon, J; Michel, P; Paillot, B; Paresy, M; Peillon, C; Scotte, M; Seng, S | 1 |
| Blaese, RM; Candotti, F; Wildner, O | 1 |
| Fukushima, S; Makino, S; Mori, S; Morimura, K; Nomura, T; Salim, EI; Wanibuchi, H; Yamamoto, S | 1 |
| Given, R; Singh, P; Varro, A; Velasco, M; Wang, TC; Wargovich, M | 1 |
| Adány, R; Balázs, M; Pásti, G; Sárváry, A; Tóth, L | 1 |
| Fukushima, S; Li, W; Nishino, H; Salim, EI; Wanibuchi, H; Wei, M; Yamamoto, S | 1 |
| Agbaria, R; Balzarini, J; Blaese, RM; Candotti, F; Johns, DG; Mullen, CA; Touraine, R | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Sakai, N; Tatsuta, M; Uehara, H; Yano, H | 1 |
| Chieco, P; Derenzini, M; Govoni, M; Pession, A; Sirri, V; Trerè, D | 1 |
| Egeli, U; Kizil, A; Tunca, B; Yerci, O; Yilmazlar, T; Zorluoglu, A | 1 |
| Alpern, HD; Davidson, RH; Erb, TA; Guiney, WB; Higgins, PJ; Jenkins, PL; Krause, JA; Parfitt, MM; Stragand, JJ; Tangel, CT; Weaver, GA | 1 |
| Cholody, WM; Kosakowska-Cholody, T; Michejda, CJ | 1 |
| Dashwood, RH; Horio, DT; Orner, GA; Xu, M | 1 |
| Lamprecht, SA; Mokady, E; Schwartz, B; Shany, S | 1 |
| Han, BS; Naito, A; Nomura, E; Park, CB; Sekine, K; Takasuka, N; Taniguchi, H; Tsuda, H; Tsuno, T | 1 |
| Hardwick, JC; Offerhaus, GJ; Peppelenbosch, MP; Van Den Brink, GR; Van Deventer, SJ | 1 |
| Ornberg, RL | 1 |
| Mełeń-Mucha, G | 1 |
| Bretland, AJ; Lawry, J; Sharrard, RM | 1 |
| Kato, N; Liu, Z; Uesaka, T; Watanabe, H | 1 |
| Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K | 1 |
| Balan, KV; Calabresi, P; Darnowski, JW; Dunaway, S; Han, Z; Hendrickson, EA; Pantazis, P; Sedivy, J; Wei, W; Wyche, JH | 1 |
| Boyer, CR; Karjian, PL; Neuteboom, ST; Pegram, M; Wahl, GM | 1 |
| Karasek, M; Kunert-Radek, J; Lawnicka, H; Pawlikowski, M; Spadoni, G; Tarzia, G; Winczyk, K | 1 |
| Bokhari, SA; Miller, MA; Qadir, K; Raza, A | 1 |
| Kellett, M; Potten, CS; Rew, DA; Roberts, SA | 1 |
| Banáth, JP; Olive, PL | 1 |
| Fowler, JF; Kinsella, TJ; Miller, EM | 1 |
| Darmon, E; Pincu-Hornstein, A; Rozen, P | 1 |
| Muro, M; Naomoto, Y; Orita, K | 1 |
| Muraoka, R; Shimomatsuya, T; Tanigawa, N | 1 |
| Cancellieri, A; Ceccarelli, C; Derenzini, M; Eusebi, V; Farabegoli, F; Trerè, D | 1 |
| Ikuta, F; Ito, Y; Ozawa, T; Saito, A; Sugiyama, Y; Takahashi, H; Takeda, N; Terabayashi, T | 1 |
| Baril, A; Billard, F; Boucheron, S; Dumollard, JM | 1 |
| Rew, DA; Taylor, I; Weaver, PC; Wilson, GD | 1 |
| Hyams, DM; Lampkin, BC; Mazewski, CM; Miller, MA; Raza, A; Sheikh, Y; White, LM; Yanik, GA; Yousuf, N | 1 |
| Drouhard, T; Lanspa, S; Lynch, HT; Lynch, J; Lynch, PM; Palmer, C; Wargovich, MJ | 1 |
| Inoue, YK; Kimura, T; Nishibe, Y | 1 |
| De Clercq, E; Iigo, M; Miwa, M | 1 |
| Bertone, A; Boidi-Trotti, A; Candelaresi, GL; Cappa, AP; Coverlizza, S; Risio, M; Rossini, FP | 1 |
| de Ley, L; de Vries, EG; Grond, J; Hardonk, MJ; Harms, G; Kleibeuker, JH; Koudstaal, J; Mulder, NH; Welberg, JW; Zwart, N | 1 |
| Ganes, DA; Wagner, JG | 1 |
| Candelaresi, GL; Coverlizza, S; Ferrari, A; Risio, M; Rossini, FP | 1 |
| Couch, DB; Gingerich, JD; Heddle, JA; Stuart, E | 1 |
| Cunningham, RE; Muller, J; Noguchi, PD; Ridge, J | 1 |
| Clarkson, BD; Duschinsky, R; Keller, O; Krakoff, IH; La Sala, E; Van Dyk, JJ | 1 |
2 trial(s) available for bromodeoxyuridine and Colonic Neoplasms
| Article | Year |
|---|---|
A phase I trial of hepatic arterial bromodeoxyuridine and conformal radiation therapy for patients with primary hepatobiliary cancers or colorectal liver metastases.
Topics: Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cholangiocarcinoma; Colonic Neoplasms; Drug Administration Schedule; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms | 1997 |
Biomarkers of human colonic cell growth are influenced differently by a history of colonic neoplasia and the consumption of acarbose.
Topics: Acarbose; Adult; Aged; Antimetabolites; Biomarkers; Bromodeoxyuridine; Carcinoma; Case-Control Studies; Cell Division; Colonic Neoplasms; Colonoscopy; Cross-Over Studies; Diet; Enzyme Inhibitors; Fatty Acids, Volatile; Female; Humans; Intestinal Mucosa; Ki-67 Antigen; Male; Middle Aged | 2000 |
102 other study(ies) available for bromodeoxyuridine and Colonic Neoplasms
| Article | Year |
|---|---|
SOX11-dependent CATSPER1 expression controls colon cancer cell growth through regulation the PI3K/AKT signaling pathway.
Topics: Animals; Bromodeoxyuridine; Calcium Channels; Colonic Neoplasms; Humans; Male; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; Semen; Signal Transduction; SOXC Transcription Factors; Transcription Factors | 2022 |
Anti-metastatic effects of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in colorectal cancer: Regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial-to-mesenchymal transition.
Topics: Actin Depolymerizing Factors; Animals; Bromodeoxyuridine; Cathepsin B; Cell Line, Tumor; Colonic Neoplasms; Extracellular Matrix; Glucose; Humans; Hydrolyzable Tannins; Interleukin-10; Interleukin-2; Interleukin-6; Mice; Tumor Necrosis Factor-alpha | 2022 |
Enhancement of radiation therapy by indoleamine 2,3 dioxygenase 1 inhibition through multimodal mechanisms.
Topics: Animals; beta Catenin; Bromodeoxyuridine; Colonic Neoplasms; HT29 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL | 2023 |
Involvement of Both Extrinsic and Intrinsic Apoptotic Pathways in Tridecylpyrrolidine-Diol Derivative-Induced Apoptosis In Vitro.
Topics: Apoptosis; Bromodeoxyuridine; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Membrane Potential, Mitochondrial; Signal Transduction | 2023 |
A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation.
Topics: Animals; Bone Marrow; Bromodeoxyuridine; Cadherins; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Epithelial Cells; Gene Expression Regulation; Hematopoietic Stem Cells; Homeostasis; Inflammation; Intestinal Mucosa; Male; Mice, Inbred C57BL; Mice, Knockout; Repressor Proteins | 2016 |
Vanadium and 1, 25 (OH)2 vitamin D3 combination in inhibitions of 1,2, dimethylhydrazine-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Bromodeoxyuridine; Calcitriol; Cell Proliferation; Colonic Neoplasms; DNA Adducts; DNA Breaks, Double-Stranded; Drug Synergism; Fluorescent Antibody Technique; Kinetics; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Vanadium | 2008 |
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cisplatin; Colonic Neoplasms; Diploidy; Disease Models, Animal; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Duplication; Mitosis; Phenotype; Polyploidy; Rats; Time Factors; Tumor Escape | 2008 |
Estrone and progesterone inhibit the growth of murine MC38 colon cancer line.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Estrone; Fluorouracil; Mice; Progesterone | 2009 |
Egg yolk proteins suppress azoxymethane-induced aberrant crypt foci formation and cell proliferation in the colon of rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bromodeoxyuridine; Carcinogens; Caseins; Cecum; Cell Proliferation; Colon; Colonic Neoplasms; DNA; Egg Proteins; Fatty Acids, Volatile; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2009 |
Anti-proliferative and apoptotic effects of etoricoxib, a selective COX-2 inhibitor, on 1,2-dimethylhydrazine dihydrochloride-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; DNA Fragmentation; Etoricoxib; Male; Proliferating Cell Nuclear Antigen; Pyridines; Rats; Rats, Sprague-Dawley; Sulfones | 2010 |
Comparison of intracellular accumulation and cytotoxicity of free mTHPC and mTHPC-loaded PLGA nanoparticles in human colon carcinoma cells.
Topics: Bromodeoxyuridine; Cell Death; Cell Membrane; Cell Proliferation; Cell Survival; Chemical Phenomena; Colonic Neoplasms; Flow Cytometry; HT29 Cells; Humans; Intracellular Space; Lactic Acid; Mesoporphyrins; Microscopy, Confocal; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spheroids, Cellular | 2011 |
Reduced tumour progression and angiogenesis in 1,2-dimethylhydrazine mice treated with NS-398 is associated with down-regulation of cyclooxygenase-2 and decreased beta-catenin nuclear localisation.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; beta Catenin; Bromodeoxyuridine; Carcinogens; Cell Nucleus; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Factor VIII; Female; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neovascularization, Pathologic; Nitrobenzenes; Prostaglandins; Signal Transduction; Sulfonamides; TCF Transcription Factors; Tumor Burden | 2011 |
Clinical outcome and bromodeoxyuridine derived proliferation indices in 100 colonic and rectal carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cohort Studies; Colonic Neoplasms; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Neoplasms, Multiple Primary; Predictive Value of Tests; Rectal Neoplasms; Staining and Labeling; Treatment Outcome | 2002 |
Variability of cell proliferation in the proximal and distal colon of normal rats and rats with dimethylhydrazine induced carcinogenesis.
Topics: Animals; Antimetabolites; Biomarkers, Tumor; Bromodeoxyuridine; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Rats; Rats, Wistar | 2002 |
Inhibition of cell growth by NB1011 requires high thymidylate synthase levels and correlates with p53, p21, bax, and GADD45 induction.
Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epithelial Cells; Female; Fibroblasts; GADD45 Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Oncogene Protein p21(ras); Protein Biosynthesis; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Detection of replicative integrity in small colonic biopsies using the BrdUrd comet assay.
Topics: Aged; Antimetabolites; Biopsy; Bromodeoxyuridine; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Comet Assay; DNA Damage; DNA, Neoplasm; Endoscopy; Female; Humans; Male; Middle Aged; Reproducibility of Results | 2003 |
GFP-transfected tumor cells are useful in examining early metastasis in vivo, but immune reaction precludes long-term tumor development studies in immunocompetent mice.
Topics: Adenocarcinoma; Animals; B-Lymphocytes; Body Weight; Bromodeoxyuridine; Cell Division; Cell Survival; Colonic Neoplasms; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunocompetence; Liver Neoplasms; Luminescent Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Microscopy, Fluorescence; T-Lymphocytes; Transfection | 2003 |
Mechanistic approach of contrasting modifying effects of caffeine on carcinogenesis in the rat colon and mammary gland induced with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Body Weight; Breast; Bromodeoxyuridine; Caffeine; Carcinogens; Central Nervous System Stimulants; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A2; DNA Adducts; DNA Repair; DNA, Single-Stranded; Female; Imidazoles; Immunohistochemistry; Liver; Mammary Neoplasms, Animal; Organ Size; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; Cell Division; Colonic Neoplasms; DNA Replication; DNA-Binding Proteins; Flow Cytometry; Humans; Hydroxyurea; Lung Neoplasms; Microscopy, Immunoelectron; Mimosine; Nuclear Proteins; RNA-Binding Proteins; Tumor Cells, Cultured; Zinc Fingers | 2003 |
Enhancement of colon carcinogenesis by prostaglandin E2 administration.
Topics: Adenocarcinoma; Animals; Apoptosis; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; Colonic Neoplasms; Dinoprostone; Disease Progression; DNA Primers; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
NB1011 induces Ser15 phosphorylation of p53 and activates the G2/M checkpoint.
Topics: Adenocarcinoma; Breast Neoplasms; Bromodeoxyuridine; Colonic Neoplasms; Humans; Phosphorylation; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Overadditive anti-proliferative and pro-apoptotic effects of a combination therapy on colorectal carcinoma cells.
Topics: Alitretinoin; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bromodeoxyuridine; Carcinoma; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Separation; Ciprofloxacin; Colonic Neoplasms; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; Indicators and Reagents; Kinetics; Prognosis; Propidium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Time Factors; Tretinoin | 2003 |
Combination therapy with Pretarget CC49 radioimmunotherapy and gemcitabine prolongs tumor doubling time in a murine xenograft model of colon cancer more effectively than either monotherapy.
Topics: Animals; Antibodies, Neoplasm; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Deoxycytidine; Female; Gemcitabine; Humans; Ligands; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Genetic; Neoplasm Transplantation; Radioimmunotherapy; Recombinant Fusion Proteins; Time Factors; Tissue Distribution | 2003 |
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Topics: Adenomatous Polyposis Coli Protein; Anaphase; Animals; Bromodeoxyuridine; CDX2 Transcription Factor; Cell Survival; Cells, Cultured; Chromosomal Instability; Colonic Neoplasms; Colonic Polyps; Epithelial Cells; Female; G1 Phase; Heterozygote; Homeodomain Proteins; Humans; In Situ Nick-End Labeling; Loss of Heterozygosity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; RNA, Antisense; S Phase; TOR Serine-Threonine Kinases; Trans-Activators | 2003 |
Identification of senescence in cancer cells.
Topics: beta-Galactosidase; Blotting, Western; Bromodeoxyuridine; Cell Division; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression Regulation, Neoplastic; Humans; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2004 |
Chemopreventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on 1, 2-dimethylhydrazine-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Benzenesulfonates; Bromodeoxyuridine; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Progression; Isoenzymes; Male; Oxazoles; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2003 |
Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bromodeoxyuridine; Carrier Proteins; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Coloring Agents; Estrogen Antagonists; Fluorouracil; Gene Expression Regulation, Neoplastic; Hormones; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasm Transplantation; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; Somatostatin; Tamoxifen; Transcription Factor RelA | 2004 |
Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters.
Topics: Animals; Benzimidazoles; Bromodeoxyuridine; Carbon Dioxide; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents | 2004 |
Anticancerogenic effect of a novel chiroinositol-containing polysaccharide from Bifidobacterium bifidum BGN4.
Topics: Antineoplastic Agents; Bifidobacterium; Bromodeoxyuridine; Cell Count; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Feces; Galactose; Glucose; Humans; Inositol; Polysaccharides, Bacterial; Rhamnose; Ribose; Trypan Blue | 2004 |
Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E2 production.
Topics: Antimetabolites; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; DNA; Enzyme Induction; Gastrins; HT29 Cells; Humans; Isoenzymes; Luciferases; Membrane Proteins; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Receptor, Cholecystokinin B; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction | 2005 |
In vivo measurement of DNA synthesis rates of colon epithelial cells in carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Azoxymethane; Body Water; Bromodeoxyuridine; Cell Cycle; Cell Proliferation; Cholic Acid; Colon; Colonic Neoplasms; Deuterium; DNA; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Kinetics; Male; Rats; Rats, Sprague-Dawley | 2005 |
A high-fat diet enhances the inhibitory effect of dietary vitamin B6 on colon cell proliferation in mice.
Topics: Animals; Apoptosis; Azoxymethane; Body Weight; Bromodeoxyuridine; Cell Proliferation; Colon; Colonic Neoplasms; Dietary Fats; Dietary Supplements; Dose-Response Relationship, Drug; Eating; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred ICR; Pyridoxine | 2005 |
Effect of concomitant polyethylene glycol and celecoxib on colonic aberrant crypt foci and tumors in F344 rats.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Celecoxib; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Cytoprotection; Drug Synergism; Female; Immunohistochemistry; Male; Polyethylene Glycols; Pyrazoles; Rats; Rats, Inbred F344; Staining and Labeling; Sulfonamides | 2005 |
Naphthyl phosphoramidate derivatives of BVdU as potential anticancer agents: design, synthesis and biological evaluation.
Topics: Amides; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Colonic Neoplasms; Female; Humans; Male; Models, Chemical; Phosphoric Acids | 2005 |
Three-dimensional analysis of isolated hexosaminidase-altered aberrant crypts from colons of 1,2-dimethylhydrazine-treated rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; beta-N-Acetylhexosaminidases; Biomarkers, Tumor; Bromodeoxyuridine; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Precancerous Conditions; Rats; Rats, Inbred F344 | 2006 |
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.
Topics: Apoptosis; Bromodeoxyuridine; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Humans; Interphase; Nitriles; Ploidies; Staurosporine; Sulfones | 2006 |
Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice.
Topics: Adenoma; Animals; Bromodeoxyuridine; Colonic Neoplasms; Disease Models, Animal; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Intestinal Neoplasms; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Ovariectomy; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transforming Growth Factor beta | 2008 |
Measurement of DNA synthesis by flow cytometry.
Topics: Adenocarcinoma; Bisbenzimidazole; Bromodeoxyuridine; Cell Line; Colonic Neoplasms; DNA; Flow Cytometry; Humans; Interphase; Mitosis; Propidium | 1981 |
Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed-field gel electrophoresis.
Topics: Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Line; Cobalt Radioisotopes; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Radiation; Electrophoresis; Humans; Kinetics; Time Factors; Tumor Cells, Cultured | 1995 |
Validation of a simple technique for the detection of abnormal mucosal cell replication in humans.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Division; Cellulose; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dietary Fiber; Galactans; Humans; Intestinal Mucosa; Male; Mannans; Metaphase; Mitosis; Plant Gums; Rats; Rats, Wistar; Rectal Neoplasms; Rectum; Reproducibility of Results; Staining and Labeling | 1994 |
Chemoprevention of azoxymethane-induced colon carcinogenesis by dietary feeding of S-methyl methane thiosulfonate in male F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Bromodeoxyuridine; Colon; Colonic Neoplasms; Diet; Male; Methyl Methanesulfonate; Nucleolus Organizer Region; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1995 |
Inhibitory effects of magnesium hydroxide on c-myc expression and cell proliferation induced by methylazoxymethanol acetate in rat colon.
Topics: Animals; Anticarcinogenic Agents; Antigens, Neoplasm; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Genes, myc; Immunohistochemistry; Magnesium Hydroxide; Male; Methylazoxymethanol Acetate; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1993 |
The effect of chenodeoxycholic acid on the development of aberrant crypt foci in the rat colon.
Topics: Animals; Antigens, Neoplasm; Body Weight; Bromodeoxyuridine; Cell Division; Chenodeoxycholic Acid; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Eating; Male; Nuclear Proteins; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 1994 |
Increased cell proliferation of azoxymethane-induced aberrant crypt foci of rat colon.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Epithelium; Kinetics; Male; Mitotic Index; Nuclear Proteins; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1994 |
Use of fluorescence in situ hybridization (FISH) to study chromosomal damage induced by radiation and bromodeoxyuridine in human colon cancer cells.
Topics: Bromodeoxyuridine; Cell Cycle; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 4; Colonic Neoplasms; G1 Phase; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Radiation Injuries; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1994 |
Resistance of aberrant crypt foci to apoptosis induced by azoxymethane in rats chronically fed cholic acid.
Topics: Animals; Apoptosis; Azoxymethane; Bromodeoxyuridine; Cholic Acid; Cholic Acids; Colonic Neoplasms; DNA; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1994 |
Enhancement of tumor proliferation by cyclosporine A in early phase of experimental hepatic metastasis.
Topics: Animals; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Cyclosporine; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation | 1994 |
Aberrant crypt foci and colon tumors in F344 rats have similar increases in proliferative activity.
Topics: Adenocarcinoma; Animals; Azoxymethane; beta-N-Acetylhexosaminidases; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Histocytochemistry; Immunohistochemistry; Male; Rats; Rats, Inbred F344 | 1994 |
Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo.
Topics: Animals; Bone Marrow; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Female; Humans; Intestine, Small; Liver; Mice; Mice, Nude; Tissue Distribution; Tumor Cells, Cultured | 1994 |
[The effect of cholecystectomy on cellular proliferation of colonic mucosa in mice].
Topics: Animals; Bromodeoxyuridine; Cell Division; Cholecystectomy; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR | 1994 |
Histone H3 messenger RNA in situ hybridization correlates with in vivo bromodeoxyuridine labeling of S-phase cells in rat colonic epithelium.
Topics: Animals; Biomarkers; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Disease Models, Animal; Epithelial Cells; Epithelium; Histones; In Situ Hybridization; Intestinal Mucosa; Male; Mice; Precancerous Conditions; Rats; Rats, Inbred F344; Reproducibility of Results; RNA, Messenger; S Phase; Starvation | 1996 |
Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase.
Topics: Animals; Azoxymethane; beta Carotene; Bromodeoxyuridine; Canthaxanthin; Carcinogens; Carotenoids; Colon; Colonic Neoplasms; Diet; Incidence; Intestinal Mucosa; Male; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred F344; Xanthophylls | 1995 |
Effect of irradiation on bromodeoxyuridine incorporation in human colon cancer xenografts.
Topics: Animals; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured | 1996 |
Cell kinetic studies using a monoclonal antibody to bromodeoxyuridine.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Cycle; Cell Line; Colonic Neoplasms; DNA; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Staining and Labeling; Tissue Fixation | 1998 |
Effects of miso and NaCl on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
Topics: Animals; Body Weight; Bromodeoxyuridine; Colonic Neoplasms; Edible Grain; Fermentation; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Sodium Chloride | 1998 |
Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest.
Topics: Blotting, Western; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Cyclin E; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flow Cytometry; G1 Phase; Humans; Infrared Rays; Models, Biological; Oncogene Proteins, Viral; Repressor Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 1999 |
Effect of radiation therapy on the potential doubling time of tumours in colorectal cancers.
Topics: Adenocarcinoma; Aneuploidy; Biopsy; Bromodeoxyuridine; Carcinoma; Cell Division; Colonic Neoplasms; Colonoscopy; Diploidy; DNA, Neoplasm; Dose Fractionation, Radiation; Flow Cytometry; Humans; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms; S Phase; Time Factors | 1999 |
Enzyme prodrug gene therapy: synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer.
Topics: Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Combined Modality Therapy; Enzyme Inhibitors; Fluorouracil; Ganciclovir; Genetic Therapy; Humans; Quinazolines; Simplexvirus; Thiophenes; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Low-dose-dependent carcinogenic potential of 2-amino-3-methylimidazo[4,5-f]quinoline in the immunodeficient (SCID) mouse colon.
Topics: Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Kidney; Liver; Male; Mice; Mice, SCID; Organ Size; Quinolines; Severe Combined Immunodeficiency | 1999 |
Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; Colonic Neoplasms; Disease Susceptibility; Gastrins; Humans; Mice; Mice, Inbred Strains; Mice, Transgenic; Precancerous Conditions; Protein Precursors | 2000 |
Effect of tumor-conditioned medium on intercellular communication and proliferation of Balb/c 3T3 cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Bromodeoxyuridine; Cell Communication; Cell Division; Colonic Neoplasms; Culture Media, Conditioned; Fluorescent Dyes; Gap Junctions; Humans; Isoquinolines; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured | 2000 |
Inhibition by ginseng of 1,2-dimethylhydrazine induction of aberrant crypt foci in the rat colon.
Topics: 1,2-Dimethylhydrazine; Animals; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Diet; Intestinal Mucosa; Male; Panax; Phytotherapy; Plants, Medicinal; Rats; Rats, Inbred F344 | 2000 |
Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric gene for metabolic suicide gene transfer.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Fibrosarcoma; Ganciclovir; Genetic Vectors; Kanamycin Kinase; Mice; Mice, Inbred C57BL; Phosphorylation; Plasmids; Recombinant Fusion Proteins; Retroviridae; Simplexvirus; Thymidine Kinase; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Antimetabolites; Apoptosis; Azoxymethane; Blotting, Western; Bromodeoxyuridine; Carcinogens; Colonic Neoplasms; Colonic Polyps; Genes, ras; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Oncogene Protein p21(ras); Point Mutation; Pravastatin; Prevalence; Protein Prenylation; Random Allocation; Rats; Rats, Wistar | 2000 |
Nucleolar size indicates the rapidity of cell proliferation in cancer tissues.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Division; Cell Nucleolus; Cell Transformation, Neoplastic; Colonic Neoplasms; Humans; Male; Mice; Mice, Nude; Neuroblastoma; Proliferating Cell Nuclear Antigen; RNA Polymerase I; Silver Staining; Time Factors; Tumor Cells, Cultured | 2000 |
The expression frequency of common fragile sites and genetic predisposition to colon cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Alu Elements; Aphidicolin; Bromodeoxyuridine; Caffeine; Child; Child, Preschool; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Colonic Neoplasms; Female; Gene Expression Profiling; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Humans; Lymphocytes; Male; Middle Aged; Pedigree | 2000 |
Bisimidazoacridones induce a potent cytostatic effect in colon tumor cells that sensitizes them to killing by UCN-01.
Topics: Adenocarcinoma; Aminoacridines; Antimetabolites, Antineoplastic; Antineoplastic Agents; beta-Galactosidase; Bromodeoxyuridine; Caspase 3; Caspases; Cell Count; Cell Cycle; Cell Death; Cell Division; Colonic Neoplasms; Coloring Agents; Humans; Tumor Cells, Cultured | 2001 |
Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz.
Topics: Administration, Oral; Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Chlorophyllides; Colonic Neoplasms; Dose-Response Relationship, Drug; Homeostasis; Male; Neoplasms, Experimental; Quinolines; Rats; Rats, Inbred F344 | 2001 |
A protective role of dietary vitamin D3 in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Bromodeoxyuridine; Calcifediol; Calcitriol; Calcium; Calcium, Dietary; Cell Division; Cholecalciferol; Colon; Colonic Neoplasms; Disease Models, Animal; Male; Random Allocation; Rats; Thymidine Kinase | 2000 |
A ferulic acid derivative, ethyl 3-(4'-geranyloxy-3-methoxyphenyl)-2-propenoate, as a new candidate chemopreventive agent for colon carcinogenesis in the rat.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Coumaric Acids; Eating; Kidney; Liver; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Terpenes | 2001 |
Leptin is a growth factor for colonic epithelial cells.
Topics: Adenocarcinoma; Animals; Bromodeoxyuridine; Carrier Proteins; Colonic Neoplasms; Epithelium; Female; Growth Substances; Humans; Leptin; Mice; Obesity; Protein Kinases; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; Thymidine; Tumor Cells, Cultured | 2001 |
Proliferation and apoptosis measurements by color image analysis based on differential absorption.
Topics: Animals; Apoptosis; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Neoplasm Transplantation; Reproducibility of Results; Tumor Cells, Cultured | 2001 |
Effects of short term treatment with pentagastrin, proglumide, tamoxifen given separately or together with 5-fluorouracil on the growth in the murine transplantable Colon 38 cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Fluorouracil; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pentagastrin; Proglumide; Tamoxifen | 2001 |
A study of death by anoikis in cultured epithelial cells.
Topics: Anoikis; Apoptosis; Bromodeoxyuridine; Carcinoma; Cell Adhesion; Cell Cycle; Cell Line; Cell Survival; Colonic Neoplasms; Enzyme Inhibitors; Epithelial Cells; Humans; Janus Kinase 2; Keratinocytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyhydroxyethyl Methacrylate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction | 2001 |
High fat diet enhances colonic cell proliferation and carcinogenesis in rats by elevating serum leptin.
Topics: 1,2-Dimethylhydrazine; Adipose Tissue; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Colonic Neoplasms; Dietary Fats; DNA, Neoplasm; Leptin; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2001 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; beta-Galactosidase; Blotting, Western; Bromodeoxyuridine; Camptothecin; Cell Cycle; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Humans; Microscopy, Fluorescence; Models, Biological; Protein Binding; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Membrane Proteins; Nucleoside Transport Proteins; Quinazolines; Thioinosine; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Effects of melatonin and melatonin receptors ligand N-[(4-methoxy-1H-indol-2-yl)methyl]propanamide on murine Colon 38 cancer growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Indoles; Ligands; Melatonin; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tumor Cells, Cultured | 2002 |
Simultaneous assessment of TGFB and cell cycle kinetics using IUdR/BrdU infusions in human neoplasms from plastic-embedded tissue.
Topics: Antibodies, Monoclonal; Biopsy; Bone Marrow; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Female; Glioblastoma; Histological Techniques; Humans; Idoxuridine; Indicators and Reagents; Kinetics; Neoplasms; S Phase; Transforming Growth Factor beta | 1992 |
Proliferation in human gastrointestinal epithelium using bromodeoxyuridine in vivo: data for different sites, proximity to a tumour, and polyposis coli.
Topics: Adenomatous Polyposis Coli; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Humans; Ileum; Intestinal Mucosa; Middle Aged; Rectal Neoplasms; Rectum | 1992 |
Growth fraction measured using the comet assay.
Topics: Animals; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Etoposide; Fluorescent Antibody Technique; Humans; Mice; Mice, Nude; Microscopy, Fluorescence; Tumor Cells, Cultured | 1992 |
Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. II. Radiosensitization of human colon cancer cells by bromodeoxyuridine.
Topics: Bromodeoxyuridine; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Radiation-Sensitizing Agents; Thymidine; Tumor Cells, Cultured | 1992 |
A rapid and simple in vitro method for evaluating human colorectal epithelial proliferation.
Topics: Antibodies, Monoclonal; Biopsy; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Epithelium; Humans; Immunoenzyme Techniques; In Vitro Techniques; Rectum; Staining and Labeling | 1990 |
Mechanism of the combined antitumor effect of natural human tumor necrosis factor-alpha and natural human interferon-alpha on cell cycle progression.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Drug Synergism; Interferon Type I; Male; Mice; Mice, Nude; Mitotic Index; Propidium; Specific Pathogen-Free Organisms; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Proliferative activity of human tumors: assessment using bromodeoxyuridine and flow cytometry.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Ploidies; Rectal Neoplasms; Stomach Neoplasms; Transplantation, Heterologous | 1991 |
AgNOR area in interphase nuclei of human tumours correlates with the proliferative activity evaluated by bromodeoxyuridine labelling and Ki-67 immunostaining.
Topics: Breast Neoplasms; Bromodeoxyuridine; Colonic Neoplasms; Goiter, Nodular; Humans; Interphase; Liver Neoplasms; Mitosis; Neoplasms; Nuclear Proteins; Nucleolus Organizer Region; Thyroid Neoplasms | 1991 |
Metastatic intracranial carcinoid with immunohistochemical observation. Case report.
Topics: Aged; Brain Neoplasms; Bromodeoxyuridine; Carcinoid Tumor; Colonic Neoplasms; Humans; Immunohistochemistry; Male; Occipital Lobe; Serotonin; Somatostatin | 1990 |
A quantitative study of epithelial alterations during the early stages of experimental colonic tumorigenesis in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Bromodeoxyuridine; Cell Count; Colon; Colonic Neoplasms; Dimethylhydrazines; Epithelium; Female; Histocytochemistry; Kinetics; Male; Mice; Mice, Inbred ICR; Mucus; S Phase | 1990 |
Proliferation characteristics of human colorectal carcinomas measured in vivo.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aneuploidy; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Diploidy; DNA, Neoplasm; Female; Flow Cytometry; Humans; Male; Middle Aged; Mitosis; Rectal Neoplasms; S Phase | 1991 |
Simultaneous immunohistochemical detection of IUdR and BrdU infused intravenously to cancer patients.
Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Humans; Idoxuridine; Immunohistochemistry; Infusions, Intravenous; Leukemia; Lymphoma; Pilot Projects; S Phase; Time Factors | 1991 |
A follow-up study of colonic epithelial proliferation as a biomarker ina Native-American family with hereditary nonpolyposis colon cancer.
Topics: Adult; Autoradiography; Biomarkers, Tumor; Bromodeoxyuridine; Cell Division; Colon; Colonic Neoplasms; Epithelial Cells; Epithelium; Family Health; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Indians, North American; Intestinal Mucosa; Male; Middle Aged; Pedigree; Tritium | 1991 |
5-Bromodeoxyuridine enhancement of Inoue-Melnick virus synthesis in human colon carcinoma cell lines.
Topics: Adenocarcinoma; Bromodeoxyuridine; Colonic Neoplasms; Humans; Tumor Cells, Cultured; Virus Replication; Viruses | 1990 |
Optimal treatment regimens for 5'-deoxy-5-fluorouridine, with or without (E)-5-(2-bromovinyl)-2'-deoxyuridine, against various tumors in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Fluorouracil; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases | 1990 |
Late cytokinetic abnormalities in irradiated rectal mucosa.
Topics: Adult; Aged; Antibodies, Monoclonal; Bromodeoxyuridine; Colonic Neoplasms; DNA; Humans; Intestinal Mucosa; Middle Aged; Neoplasms, Radiation-Induced; Rectal Neoplasms; Rectum | 1990 |
Proliferation rate of colonic mucosa in normal subjects and patients with colonic neoplasms: a refined immunohistochemical method.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Count; Cell Division; Colon; Colonic Neoplasms; Female; Humans; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestinal Polyps; Male; Middle Aged; Risk Factors | 1990 |
The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells.
Topics: Bromodeoxyuridine; Cell Line; Cell Survival; Colonic Neoplasms; DNA; DNA Damage; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Idoxuridine; In Vitro Techniques; Radiation-Sensitizing Agents | 1990 |
Improved high-performance liquid chromatographic assay for the quantification of 5-bromo-2'-deoxyuridine and 5-bromouracil in plasma.
Topics: Aged; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Humans; Indicators and Reagents; Infusions, Intravenous; Liver Neoplasms; Male; Uracil | 1988 |
Immunohistochemical study of epithelial cell proliferation in hyperplastic polyps, adenomas, and adenocarcinomas of the large bowel.
Topics: Adenocarcinoma; Adenoma; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Colonic Polyps; Epithelial Cells; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Intestinal Polyps; Male; Rectal Neoplasms | 1988 |
Induction of sister chromatid exchanges in murine colonic tissue.
Topics: 1,2-Dimethylhydrazine; Animals; Bromodeoxyuridine; Chromosome Aberrations; Colon; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Epithelium; Female; Metaphase; Mice; Mice, Inbred C57BL; Sister Chromatid Exchange; Time Factors | 1986 |
The use of flow cytometry and cell sorting in a human colon carcinoma model.
Topics: Animals; Bromodeoxyuridine; Carcinoembryonic Antigen; Cell Division; Cell Line; Cell Separation; Chick Embryo; Colonic Neoplasms; DNA, Neoplasm; Flow Cytometry; Humans | 1985 |
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Colonic Neoplasms; Deoxyuridine; Dogs; Female; Floxuridine; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Ileocecal Valve; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma; Stomach Neoplasms | 1967 |