Page last updated: 2024-08-17

bromodeoxyuridine and Bloom Syndrome

bromodeoxyuridine has been researched along with Bloom Syndrome in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199016 (64.00)18.7374
1990's5 (20.00)18.2507
2000's3 (12.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lansdorp, PM; van Wietmarschen, N1
Ellis, NA; Farnsworth, J; Garfield, SH; Harris, CC; Linke, SP; Pedeux, R; Sengupta, S; Shay, JW; Valerie, K; Wasylyk, B; Yang, Q1
Celeste, A; Chen, J; Halazonetis, TD; Harris, CC; Linke, SP; Nussenzweig, A; Pedeux, R; Robles, AI; Sengupta, S; Sinogeeva, NI; Ward, IM; Zhang, R1
Alhadeff, B; German, J1
Furuyama, J; Hashimoto, T; Lopetegui, P; Sukenaga, T1
Sandberg, AA; Shiraishi, Y; Yosida, TH2
D'Andrea, A; Kaiser, TN; Latt, SA; Lester, S; Sakai, K; Schlesinger, F; Schreck, RR1
German, J; Ray, JH1
Alhadeff, B; Siniscalco, M1
Kapp, LN1
Ogata, T; Shiraishi, Y; Soma, H1
Hoehn, H; Poot, M; Rüdiger, HW1
Li, MJ; Shiraishi, Y2
Kerrigan, D; Kraemer, KH; Pommier, Y; Rünger, TM1
Hoehn, H; Nicotera, TM; Poot, M; Rüdiger, HW1
Heartlein, MW; Latt, SA; Tsuji, H2
Shiraishi, Y1
German, J; Louie, E; Ray, JH1
Ohtsuki, Y; Shiraishi, Y1
Fujikawa-Yamamoto, K; Kurihara, T; Murakami, F; Odashima, S1
Fujiwara, Y; Yamamoto, Y1
Kojima, T; Tsuji, H1

Other Studies

25 other study(ies) available for bromodeoxyuridine and Bloom Syndrome

ArticleYear
Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells.
    Nucleic acids research, 2016, 08-19, Volume: 44, Issue:14

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Division; DNA; Fibroblasts; Humans; Lymphocytes; Sister Chromatid Exchange; Templates, Genetic

2016
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination.
    The EMBO journal, 2003, Mar-03, Volume: 22, Issue:5

    Topics: Active Transport, Cell Nucleus; Adenosine Triphosphatases; Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Cell Line; DNA Helicases; DNA Replication; DNA-Binding Proteins; Fibroblasts; Humans; Hydroxyurea; Models, Genetic; Nuclear Proteins; Phosphorylation; Protein Binding; Rad51 Recombinase; Recombination, Genetic; RecQ Helicases; Serine; Tumor Suppressor Protein p53

2003
Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
    The Journal of cell biology, 2004, Sep-13, Volume: 166, Issue:6

    Topics: Bloom Syndrome; Blotting, Western; Bromodeoxyuridine; Carrier Proteins; Cell Line; Checkpoint Kinase 1; DNA Damage; DNA Helicases; Fibroblasts; Humans; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Kinetics; Microscopy, Confocal; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; RNA, Small Interfering; S Phase; Tumor Suppressor p53-Binding Protein 1

2004
Analysis of sister-chromatid exchanges.
    Current protocols in human genetics, 2001, Volume: Chapter 8

    Topics: Azure Stains; Bisbenzimidazole; Bloom Syndrome; Bromodeoxyuridine; Cytogenetic Analysis; Female; Genetics, Medical; Humans; Metaphase; Pregnancy; Prenatal Diagnosis; Sister Chromatid Exchange

2001
Different properties in lymphoblastoid cell lines from patients with Bloom syndrome.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: B-Lymphocytes; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transformation, Viral; Chromosome Aberrations; Ethyl Methanesulfonate; Herpesvirus 4, Human; Humans; Sister Chromatid Exchange

1984
Analyses of bromodeoxyuridine-associated sister chromatid exchanges (SCEs) in Bloom syndrome based on cell fusion: single and twin SCEs in endoreduplication.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:14

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Cell Fusion; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Crossing Over, Genetic; Herpesvirus 4, Human; Humans; Karyotyping; Kinetics; Sister Chromatid Exchange

1983
Detection, significance, and mechanism of sister chromatid exchange formation: past experiments, current concepts, future challenges.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; DNA Repair; DNA Replication; Fanconi Anemia; Humans; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange

1984
Bloom's syndrome and EM9 cells in BrdU-containing medium exhibit similarly elevated frequencies of sister chromatid exchange but dissimilar amounts of cellular proliferation and chromosome disruption.
    Chromosoma, 1984, Volume: 90, Issue:5

    Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cricetinae; Cricetulus; Female; Humans; Lymphocytes; Male; Ovary; Sister Chromatid Exchange

1984
Complementation studies in murine/human hybrids suggest multiple etiology for increased rate of sister chromatid exchange in mammalian cells.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cell Line; DNA Repair; Fibroblasts; Gardner Syndrome; Genetic Complementation Test; Humans; Hybrid Cells; L Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mutation; Sister Chromatid Exchange

1984
DNA fork displacement rates in Bloom's syndrome fibroblasts.
    Biochimica et biophysica acta, 1982, Feb-26, Volume: 696, Issue:2

    Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cell Line; DNA; DNA Replication; Photolysis

1982
Enhanced expression of stomach cancer antigen derived from malignantly transformed bloom syndrome cells previously labeled with bromodeoxyuridine.
    Cancer genetics and cytogenetics, 1992, Volume: 62, Issue:1

    Topics: Antibodies, Neoplasm; Antigens, Neoplasm; Bloom Syndrome; Blotting, Western; Bromodeoxyuridine; Cell Line, Transformed; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Sister Chromatid Exchange; Stomach Neoplasms; Thymidine

1992
Detection of free radical-induced DNA damage with bromodeoxyuridine/Hoechst flow cytometry: implications for Bloom's syndrome.
    Mutation research, 1990, Volume: 238, Issue:3

    Topics: B-Lymphocytes; Bisbenzimidazole; Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Cell Transformation, Viral; DNA; DNA Damage; Fibroblasts; Flow Cytometry; Free Radicals; Herpesvirus 4, Human; Humans; Oxygen

1990
A unique human mutant B-lymphoblastoid cell line (ataxia telangiectasia) which exhibits increased sister-chromatid exchange retaining hypersensitivity to neocarzinostatin and bleomycin.
    Mutation research, 1990, Volume: 230, Issue:2

    Topics: Antibiotics, Antineoplastic; Ataxia Telangiectasia; B-Lymphocytes; Bleomycin; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Drug; Humans; Mutation; Sister Chromatid Exchange; Zinostatin

1990
Relationship of DNA strand breakage produced by bromodeoxyuridine to topoisomerase II activity in Bloom-syndrome fibroblasts.
    Mutation research, 1991, Volume: 254, Issue:2

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; DNA; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Fibroblasts; Gamma Rays; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; X-Rays

1991
Bromodeoxyuridine (BrdU) template and thymidine pool effects on high frequencies of sister-chromatid exchange (SCE) in Bloom syndrome cells and a mutant cell line (AsHa) originated from ataxia telangiectasia.
    Mutation research, 1990, Volume: 230, Issue:2

    Topics: Ataxia Telangiectasia; Bloom Syndrome; Bromodeoxyuridine; Cell Fusion; Cell Line; Diploidy; Dose-Response Relationship, Drug; Humans; Mitosis; Mutation; Sister Chromatid Exchange; Templates, Genetic; Thymidine

1990
Cell kinetic evidence suggests elevated oxidative stress in cultured cells of Bloom's syndrome.
    Free radical research communications, 1989, Volume: 7, Issue:3-6

    Topics: Bisbenzimidazole; Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Cell Line, Transformed; Cells, Cultured; Ethidium; Fibroblasts; Flow Cytometry; Humans; Interphase; Lipid Peroxidation; Oxidation-Reduction

1989
Disparate effects of 5-bromodeoxyuridine on sister-chromatid exchanges and chromosomal aberrations in Bloom syndrome fibroblasts.
    Mutation research, 1988, Volume: 198, Issue:1

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Deoxycytidine; Fibroblasts; Floxuridine; Humans; Sister Chromatid Exchange

1988
Effects of cell fusion and deoxynucleosides on sister-chromatid exchanges in B-lymphoblastoid cell lines from 5 Bloom syndrome patients.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: B-Lymphocytes; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Fusion; Deoxyribonucleosides; DNA Repair; Floxuridine; Genetic Complementation Test; Humans; In Vitro Techniques; Sister Chromatid Exchange

1988
5-Bromodeoxyuridine-dependent increase in sister chromatid exchange formation in Bloom's syndrome is associated with reduction in topoisomerase II activity.
    Experimental cell research, 1987, Volume: 169, Issue:1

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Line; DNA Topoisomerases, Type II; Fluorescent Antibody Technique; Humans; Kinetics; Sister Chromatid Exchange

1987
Different mutations are responsible for the elevated sister-chromatid exchange frequencies characteristic of Bloom's syndrome and hamster EM9 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:8

    Topics: Animals; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Fusion; Cell Line; Chromosomes, Human; Cricetinae; Humans; Hybrid Cells; Mutation; Sister Chromatid Exchange

1987
SCE levels in Bloom-syndrome cells at very low bromodeoxyuridine (BrdU) concentrations: monoclonal anti-BrdU antibody.
    Mutation research, 1987, Volume: 176, Issue:1

    Topics: Antibodies, Monoclonal; Bloom Syndrome; Bromodeoxyuridine; Cell Line; Humans; Immunoenzyme Techniques; Sister Chromatid Exchange

1987
DNA synthesis in Bloom's syndrome fibroblasts.
    Cell and tissue kinetics, 1987, Volume: 20, Issue:1

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Count; Cells, Cultured; DNA; Fibroblasts; Flow Cytometry; Humans; Interphase; Kinetics; Mitosis

1987
Abnormal regulation of uracil-DNA glycosylase induction during cell cycle and cell passage in Bloom's syndrome fibroblasts.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cells, Cultured; DNA; DNA Glycosylases; Enzyme Induction; Fibroblasts; Humans; N-Glycosyl Hydrolases; Sister Chromatid Exchange; Thymidine; Tritium; Uracil-DNA Glycosidase

1986
Inhibition of bromodeoxyuridine-associated sister chromatid exchanges in Bloom's syndrome cells with cycloheximide.
    Cancer genetics and cytogenetics, 1985, Volume: 17, Issue:1

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Line; Cycloheximide; Deoxycytidine; Humans; Karyotyping; Mitosis; Sister Chromatid Exchange

1985
Presence of abnormally high incidences of sister chromatid exchanges in three successive cell cycles in Bloom's syndrome lymphocytes.
    Chromosoma, 1985, Volume: 93, Issue:1

    Topics: Bloom Syndrome; Bromodeoxyuridine; Cell Cycle; Chromosome Aberrations; Humans; Lymphocyte Activation; Lymphocytes; Sister Chromatid Exchange

1985