bromodeoxyuridine has been researched along with Aging in 351 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (4.56) | 18.7374 |
| 1990's | 68 (19.37) | 18.2507 |
| 2000's | 183 (52.14) | 29.6817 |
| 2010's | 81 (23.08) | 24.3611 |
| 2020's | 3 (0.85) | 2.80 |
| Authors | Studies |
|---|---|
| Chillón, M; Companys-Alemany, J; Griñán-Ferré, C; Pallàs, M; Roig-Soriano, J; Turcu, AL; Vázquez, S | 1 |
| Askew, KE; Fryatt, GL; Gomez-Nicola, D | 1 |
| Baum, E; Dahab, M; Günther, M; Karapetow, L; Kathner-Schaffert, C; Keiner, S; Lehmann, T; Redecker, C; Rudolph, M; Schmeer, CW; Witte, OW | 1 |
| Chang, JC; Chao, YC; Fan, X; Hu, CH; Liu, CS; Sen, Y; Wu, HC | 1 |
| Hang, R; Hu, F; Li, C; Xu, R; Zhang, C; Zhu, L | 1 |
| Gu, Y; He, C; Hu, X; Huang, X; Qin, S; Su, Z; Sun, X; Tan, Z; Wang, D; Yuan, Y | 1 |
| Inoue, K; Llorens-Martín, M; Nishijima, T; Soya, H; Tejeda, GS; Torres-Alemán, I; Trejo, JL; Yamamura, Y | 1 |
| Glasper, ER; Gould, E | 1 |
| Alenina, N; Bader, M; Beis, D; Kempermann, G; Klempin, F; Mosienko, V | 1 |
| Bonfanti, L; Conte, D; Crociara, P; Fumagalli, M; Parolisi, R | 1 |
| David, LS; Saghatelyan, A; Schachner, M | 1 |
| Chapouton, P; Edelmann, K; Fritschle, M; Glashauser, L; Godinho, L; Hesl, B; Ninkovic, J; Sprungala, S | 1 |
| Díaz-Moreno, M; Eguiluz, C; García-Bermúdez, E; García-Carpio, I; Gonçalves, A; Hortigüela, R; Manich, G; Mira, H; Moreno-Estellés, M; Pelegrí, C; Vilaplana, J; Vilar, M | 1 |
| Beltran-Frutos, E; Bernal-Mañas, CM; Canteras, M; Cortes, S; Ferrer, C; Horn, R; Morales, E; Pastor, LM; Seco-Rovira, V | 1 |
| Jeon, HJ; Kim, YS; Lee, SH; Na, HJ; Park, JS; Pyo, JH; Yoo, MA | 1 |
| Hashimoto, R; Hideshima, K; Kanno, T; Matsumoto, A; Otani, H; Sekine, J; Tatsumi, H | 1 |
| Brocardo, PS; Choquette, W; Christie, BR; Gil-Mohapel, J; Gothard, R; Simpson, JM | 1 |
| Auwerx, J; Essabri, K; Koutseff, A; Meziane, H; Mittelhaeuser, C | 1 |
| Ilieş, I; Sîrbulescu, RF; Traniello, IM; Zupanc, GK | 1 |
| Chang, SP; Kenyon, CJ; Morley, SD; Morrison, HD; Nilsson, F; West, JD | 1 |
| DonCarlos, LL; Mohr, MA; Sisk, CL; Staffend, NA | 1 |
| Jinno, S; Yamada, J | 1 |
| Imai, S; Stein, LR | 1 |
| Bao, X; Cai, Y; Chen, J; Fan, X; Huang, J; Huang, W; Sun, D; Xu, H; Zhao, J | 1 |
| Abbracchio, MP; Boda, E; Buffo, A; Di Maria, S; Rosa, P; Taylor, V | 1 |
| Hoeijmakers, L; Kakava-Georgiadou, N; Korosi, A; Lazic, SE; Lucassen, PJ; Meesters, A; Naninck, EF | 1 |
| Hara, T; Hashimoto, M; Inoue, T; Katakura, M; Matsuzaki, K; Shido, O | 1 |
| Almeida, F; Álvarez-Simón, CB; Blanco, V; Cano, JC; Castro-Garcia, P; Díaz-Moreno, M; Fernández-Gómez, FJ; Gil-Gas, C; Honrubia-Gómez, P; Jordán, J; Mira, H; Ramírez-Castillejo, C; Sánchez-Sánchez, F | 1 |
| Fernando Takase, L; Maragno, H; Rodella, P; Silva Freitas, Jd | 1 |
| Aguirre, A; Birey, F | 1 |
| Holdt, T; Karl, MO; Löffler, K; Schäfer, P; Völkner, M | 1 |
| Ballesteros, I; García-Culebras, A; Hernández-Jiménez, M; Lizasoain, I; Moraga, A; Moro, MA; Palma-Tortosa, S; Pradillo, JM | 1 |
| Assis, LH; Bogerd, J; Crespo, D; França, LR; Morais, RD; Schulz, RW | 1 |
| Chen, BY; Chen, LW; Kuang, F; Liu, JT; Zhang, JQ | 1 |
| Chen, J; Jiao, SS; Li, CR; Liu, J; Wang, YJ; Xu, ZQ; Yang, H; Zhang, T | 1 |
| Epstein, T; Landis, RW; Latham, JD; Maurer, LL; Philbert, MA; Song, DH | 1 |
| Chen, M; Forrester, JV; Fraczek, M; Luo, C; Rajapakse, D; Xu, H | 1 |
| Cheng, Z; Li, YQ; Wong, CS | 1 |
| Asahara, M; Bessho, K; Huang, B; Kiso, H; Motokawa, M; Saito, K; Shimizu, A; Slavkin, HC; Sugai, M; Takahashi, K; Togo, Y; Tsukamoto, H | 1 |
| Jang, S; Jeong, J; Kim, CH; Kim, E; Kim, EW; Kim, H; Lee, JE; Lee, SK; Namkoong, K; Park, M | 1 |
| Byrd-Jacobs, CA; Trimpe, DM | 1 |
| García-Cabrerizo, R; García-Fuster, MJ | 1 |
| Costa, GM; Figueiredo, AF; França, LR; Hess, RA | 1 |
| Chartier, SR; Mantyh, PW; Mitchell, SA; Thompson, ML | 1 |
| Cabrera-Muñoz, EA; Flores-Ramos, M; Galindo-Sevilla, N; Hernández-Luis, F; Herrera-Pérez, JJ; Jiménez-Rubio, G; Martínez-Mota, L; Ortiz-López, L; Ramírez-Rodríguez, GB; Zambrano, E | 1 |
| Ball, GF; Balthazart, J; Cornil, CA; Shevchouk, OT | 1 |
| Chan, CCH; Chau, BKH; Cheng, L; Fung, TKH; Lau, BWM; Lau, WKW; Lee, TMC; Liang, Y; So, KF; Wang, T; Wang, Z | 1 |
| Bruening, S; Gleason, G; Tatapudy, S; Toth, M | 1 |
| Rajendran, RS; Wellbrock, UM; Zupanc, GK | 1 |
| Bárdos, G; Béldi, M; Takács, J; Világi, I | 1 |
| Dar, DE; Gersner, R; Levit, O; Raizel, H; Richter-Levin, G; Toth, E; Wilf-Yarkoni, A; Zangen, A | 1 |
| Boer, PA; Cavalcanti, TC; Ferrari, AL; Lopes de Faria, JB; Lopes de Faria, JM; Rosales, MA; Silva, KC | 1 |
| Brewer, GJ; Jones, TT | 1 |
| Blomgren, K; Cooper-Kuhn, C; Kuhn, HG; Nilsson, M; Qiu, L; Wang, X; Xu, F; Zhu, C | 1 |
| Kohsaka, S; Maekawa, M; Namba, T; Uchino, S; Yuasa, S | 1 |
| Fornal, CA; Jacobs, BL; Takase, LF | 1 |
| Aigner, L; Aigner, R; Bogdahn, U; Caioni, M; Couillard-Despres, S; Kandasamy, M; Stadler, K; Wuertinger, C | 1 |
| Ahmed, EI; DonCarlos, LL; Lorenz, BH; Schulz, KM; Sisk, CL; Zehr, JL | 1 |
| Berghard, A; Bohm, S; Molander, M; Vedin, V | 1 |
| Derby, CD; Edwards, DH; Johnstone, LM; Schmidt, M; Song, CK | 1 |
| Booth, FW; Childs, TE; Jump, SS; Lees, SJ; Zwetsloot, KA | 1 |
| Allodi, S; Beltz, BS; Sandeman, DC; Zhang, Y | 1 |
| Honda, N; Inamura, K; Kashiwayanagi, M; Sakamoto, H | 1 |
| Horner, PJ; Lasiene, J; Matsui, A; Sawa, Y; Wong, F | 1 |
| Bagorda, F; Brummelte, S; Schaefers, AT; Teuchert-Noodt, G | 1 |
| Bachstetter, AD; Baradez, MO; Eve, DJ; Gemma, C; Musso, J; Park, DH; Sanberg, PR; Schlunk, A; Sinden, JD; Wolfson, A | 1 |
| Hodes, GE; Santollo, J; Shors, TJ; Van Kooy, J; Yang, L | 1 |
| Chen, F; Chen, X; Kaufman, DB; Larson, CS; Wang, LJ; Zhang, X | 1 |
| Mizoguchi, K; Tanaka, Y | 1 |
| Brothers, HM; Marchalant, Y; Wenk, GL | 1 |
| Barlind, A; Björk-Eriksson, T; Blomgren, K; Isgaard, J; Karlsson, N | 1 |
| Kawada, K; Ogita, K; Yoneyama, M | 1 |
| Keiner, S; Redecker, C; Walter, J; Witte, OW | 1 |
| Gulyaeva, NV; Lazareva, NA; Moiseeva, YV; Onufriev, MV; Stepanichev, MY | 1 |
| Griffin, EA; Holtzman, DM; Jones, LA; Lim, MM; Mach, RH; Mintun, MA; Pan, F; Sheline, YI; Zeng, C | 1 |
| Fleischmann, BK; Jovinge, S; Pontén, A; Walsh, S | 1 |
| Amaral, DG; Jabès, A; Lavenex, P; Lavenex, PB | 1 |
| Borgonie, G; De Mulder, K; Egger, B; Eichberger, P; Kuales, G; Ladurner, P; Pfister, D; Seppi, T | 1 |
| Feng, KL; Lin, PY; Tai, MY; Tsai, YF; Wang, SP; Wu, YS | 1 |
| Alpár, A; Bauer, U; Gärtner, U; Grosche, J; Härtig, W; Künzle, H; Popkova, Y; Reichenbach, A | 1 |
| Hattiangady, B; Rao, MS; Shetty, AK; Shuai, B | 1 |
| Jamen, F; Psachoulia, K; Richardson, WD; Young, KM | 1 |
| Lee, Y | 1 |
| Kaga, K; Kanaya, K; Kondo, K; Nibu, K; Sakamoto, T; Suzukawa, K; Ushio, M; Watanabe, K; Yamaguchi, T; Yamasoba, T | 1 |
| Buchholz, BA; Harlan, DM; Hsieh, M; Kirby, M; Kushner, JA; Liu, EH; Meeker, AK; Pechhold, S; Perl, S; Stein, GM; Tisdale, JF | 1 |
| Beebe, DC; Shui, YB; Wiley, LA | 1 |
| Funakoshi, H; Hagihara, H; Kanai, M; Miyakawa, T; Nakamura, T; Ohira, K; Takao, K; Toyama, K | 1 |
| Belluardo, N; Di Liberto, V; Frinchi, M; Fuxe, K; Mudò, G; Olivieri, M | 1 |
| Friedlander, RM; Tomycz, ND | 1 |
| Akai, S; Fujii, E; Isobe, K; Kato, A; Soshin, T; Suzuki, M; Takai, Y; Watanabe, T; Yamazaki, M | 1 |
| Hvid, H; Jensen, HE; Oleksiewicz, MB; Sjögren, I; Thorup, I | 1 |
| Miyakawa, T; Ohira, K | 1 |
| Bello-Medina, PC; Martínez-Claros, M; Pérez, O; Ramírez-Amaya, V; Sandoval, CJ | 1 |
| Herbert, J; Liu, JX; Pinnock, SB | 1 |
| Ehninger, D; Kempermann, G; Kettenmann, H; Klempin, F; Römer, B; Wang, LP | 1 |
| Barnes, CA; Marrone, DF; Ramirez-Amaya, V | 1 |
| Bhattacharya, TK; DeYoung, EK; Kohman, RA; Peterson, LN; Rhodes, JS | 1 |
| Anglés, N; Boada, M; Bolea, I; Comes, G; Escorihuela, RM; Fernández-Fernández, L; Hidalgo, J; Morelló, JR; Murtra, P; Ramirez, B; Reguant, J; Ruiz, J; Unzeta, M; Valente, T | 1 |
| Hiromura, K; Ikeuchi, H; Kuroiwa, T; Maeshima, A; Mishima, K; Miya, M; Nojima, Y; Sakurai, N | 1 |
| Colello, RJ; McGinn, MJ; Sun, D | 1 |
| Horne, MK; Stanić, D; Sui, Y | 1 |
| Gulliver, LS; Hurst, PR | 1 |
| Bader, DM; Dees, E; Galindo, CL; Hunt, RP; Miller, PM; Moynihan, KL; Pooley, RD; Rottman, JN | 1 |
| Ansorg, A; Urbach, A; Witte, OW | 1 |
| Foster, TC; Kumar, A; Ormerod, BK; Pastoriza, JM; Rani, A; Severance, JE; Speisman, RB | 1 |
| Bessert, D; Skoff, RP; Tatar, C; Tse, H | 1 |
| Bhattacharya, TK; Bucko, P; Kilby, C; Kohman, RA; Rhodes, JS | 1 |
| Alvarez-Buylla, A; Petreanu, L | 1 |
| Gray, WP; May, K; Sundström, LE | 1 |
| Shetty, AK; Zaman, V | 2 |
| Johnson, KM; Owen, K; Witte, PL | 1 |
| Antropova, YG; Bryantsev, AL; Il'inskaya, OP; Kalinina, NI; Tararak, EM | 1 |
| Abe, K; Furuse, T; Miura, Y; Noda, Y; Suzuki, S; Tatsumi, K; Urano, S | 1 |
| Alexandrunas, D; Bickenbach, JR; Chinnathambi, S; Dunnwald, M | 1 |
| Galea, LA; Lee, TT; Ormerod, BK | 1 |
| Kim, JS; Lee, SH; Lee, YS; Son, H; Yu, IT | 1 |
| Aloe, L; Amendola, T; Fiore, M; Tirassa, P; Triaca, V | 1 |
| Absil, P; Balthazart, J; Eens, M; Pinxten, R | 1 |
| Baughman, AM; Goto, T; Kishi, S; Lin, MC; Tsai, SB; Uchiyama, J | 1 |
| Bizon, JL; Gallagher, M | 1 |
| Holbrook, NJ; Li, J | 1 |
| Lang, H; Schmiedt, RA; Schulte, BA | 1 |
| Inenaga, C; Kakita, A; Sakamoto, M; Takahashi, H | 1 |
| Azcoitia, I; Garcia-Segura, LM; Hales, DB; Lavaque, E; Perez-Martin, M; Sierra, A | 1 |
| Capecchi, MR; Wintch, HD; Wong, KH | 1 |
| Chen, S; Coggeshall, RE; Corfas, G; Dikkes, P; Ji, RR; Rio, C; Woolf, CJ | 1 |
| Aigner, L; Brown, JP; Cooper-Kuhn, CM; Couillard-Després, S; Kuhn, HG; Winkler, J | 1 |
| Abrous, DN; Aurousseau, C; Drapeau, E; Le Moal, M; Mayo, W; Piazza, PV | 1 |
| de la Rosa, EJ; Hallböök, F; Mayordomo, R; Valenciano, AI | 1 |
| Coe, CL; Czéh, B; Fuchs, E; Gould, E; Kirschbaum, C; Kramer, M; Reeves, AJ | 1 |
| Jasper, PJ; Kalis, SL; Kingzette, M; Knight, KL; Zhai, SK | 1 |
| Chichung Lie, D; Evans, RM; Gage, FH; Nakashima, K; Ray, J; Shi, Y; Taupin, P; Yu, RT | 1 |
| Chang, HK; Jang, MH; Jeong, IG; Kim, CJ; Kim, H; Kim, YP; Lee, HH; Lee, SJ; Shin, MC; Shin, MS; Yoon, JH | 1 |
| Ikeda, E; Kawamura, K; Maeda, N; Noda, M; Ohyama, K | 1 |
| Barone, TA; Maslov, AY; Plunkett, RJ; Pruitt, SC | 1 |
| Dunnett, SB; Fricker-Gates, RA; Gates, MA; White, A | 1 |
| Hamada, H; Nishijima, M; Nishino, J; Saijoh, Y; Sakai, Y; Uehara, M; Yamashita, K; Yashiro, K; Zhao, X | 1 |
| Ambrogini, P; Benedetti, S; Cecchini, T; Ciaroni, S; Cuppini, R; Del Grande, P; Ferri, P; Pagliarani, S; Papa, S; Santi, S | 1 |
| Bumaschny, VF; de Souza, FS; Hentges, ST; Low, MJ; Overstreet, LS; Rubinstein, M; Santangelo, AM; Smart, JL; Westbrook, GL | 1 |
| Bondolfi, L; Ermini, F; Ingram, DK; Jucker, M; Long, JM | 1 |
| Arlotta, P; Cage, TA; Catapano, LA; Macklis, JD | 1 |
| Abizaid, A; Horvath, TL; Mezei, G; Sotonyi, P | 1 |
| Chen, TL | 1 |
| Kishi, S | 1 |
| Bizon, JL; Gallagher, M; Lee, HJ | 1 |
| Allman, DM; Cancro, MP; Gerstein, RM; Labrie, JE; Sah, AP | 1 |
| Al-Awqati, Q; Cheema, FH; Maarouf, O; Martens, TP; Oliver, JA | 1 |
| Alway, SE; Butler, DC; Pistilli, EE; Siu, PM | 1 |
| Bartke, A; Evans, MS; Hsieh, J; Panici, J; Sun, LY | 1 |
| Greenberg, DA; Jin, K; Mao, XO; Minami, M; Simon, RP; Sun, Y; Wang, Y; Xie, L | 1 |
| Kim, H; Oppenheim, RW; Park, OH; Sun, W; Vinsant, S; Winseck, A | 1 |
| Larsson, A; Pekna, M; Pekny, M; Wilhelmsson, U | 1 |
| Abdel-Rahman, A; Hattiangady, B; Rao, MS; Shetty, AK; Stanley, DP | 1 |
| Arnold, SE; Borgmann-Winter, K; Hahn, CG; Han, LY; Lenox, RH; Mirza, N; Rawson, NE | 1 |
| Burns, KA; Kuan, CY | 1 |
| Baram, TZ; Bender, RA; Brunson, KL | 1 |
| Chopp, M; Meng, H; Wang, Y; Zhang, C; Zhang, L; Zhang, RL; Zhang, ZG | 1 |
| Casadesus, G; Joseph, JA; Rabin, BM; Shukitt-Hale, B; Smith, MA; Stellwagen, HM | 1 |
| Gilbert, ME; Goodman, JH; Kelly, ME; Samsam, TE | 1 |
| Fukunaga, A | 1 |
| Ariznavarreta, C; Azcoitia, I; Castillo, C; Garcia-Segura, LM; Perez-Martin, M; Salazar, V; Tresguerres, JA | 1 |
| Acker, CM; Andorfer, C; Davies, P; Duff, K; Hof, PR; Kress, Y | 1 |
| Agashe, S; Daniel, SM; Desouza, LA; Ladiwala, U; Vaidya, RA; Vaidya, VA | 1 |
| Czéh, B; Fuchs, E; Simon, M | 1 |
| Abrous, DN; Aurousseau, C; Drapeau, E; Dupret, D; Kitchener, P; Le Moal, M; Montaron, MF; Piazza, PV | 1 |
| McDonald, HY; Wojtowicz, JM | 1 |
| Darsalia, V; Heldmann, U; Kokaia, Z; Lindvall, O | 1 |
| Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C | 1 |
| Abrous, DN; Aurousseau, C; Drapeau, E; Dupret, D; Le Moal, M; Montaron, MF; Piazza, PV | 1 |
| Kaur, P; Webb, A | 1 |
| Ambrogini, P; Baldi, E; Bucherelli, C; Ciuffoli, S; Cuppini, R; Ferri, P; Orsini, L | 1 |
| Fukuda, H; Hayashi, S; Kanagawa, T; Murata, Y; Shimoya, K; Shioji, M; Tomimatsu, T | 1 |
| Dinca, I; Kessler, C; Kroemer, H; Popa-Wagner, A; Walker, L; Yalikun, S | 1 |
| Debeir, T; François, C; Freundlieb, N; Hirsch, EC; Höglinger, G; Tandé, D | 1 |
| Kanba, S; Kudo, K; Kuroki, T; Qiao, C; Wati, H | 1 |
| Bonder, EM; Chen, G; Cheng, MF | 1 |
| Brooks, WM; Driscoll, I; Howard, SR; Monfils, MH; Stone, JC; Sutherland, RJ; Tomanek, B | 1 |
| García-Verdugo, JM; Mora, F; Segovia, G; Yagüe, AG | 1 |
| Lavker, RM; Leiberman, J; Xu, J; Zhou, M | 1 |
| Boussemaere, M; Denef, C; Pals, K; Swinnen, E; Vankelecom, H | 1 |
| Chang, YC; Ho, CJ; Huang, AM; Huang, CC; Lee, HT; Tzeng, SF; Yu, L | 1 |
| Bhardwaj, RD; Björk-Eriksson, T; Buchholz, BA; Curtis, MA; Druid, H; Eriksson, PS; Fink, D; Frisén, J; Gage, FH; Nordborg, C; Spalding, KL | 1 |
| Fukuda, H; Fukui, O; Hayashi, S; Kanagawa, T; Komoto, Y; Murata, Y; Shimoya, K; Tsubouchi, H | 1 |
| Acosta, CA; Douglas-Price, AL; Forriol, F; Izal, I; Ripalda, P | 1 |
| Blomgren, K; Cooper-Kuhn, CM; Eriksson, PS; Kuhn, HG; Nilsson, M; Qiu, L; Wang, X; Xu, F; Zhu, C | 1 |
| Kaga, K; Kondo, K; Nibu, K; Takeuchi, N; Watanabe, K | 1 |
| Kundel, DW; Nikolai, S; Rose-Hellekant, TA; Sandgren, EP; Wentworth, KM | 1 |
| Hattiangady, B; Shetty, AK | 1 |
| Aznar, S; Husum, H; Høyer-Hansen, S; Larsen, MH; Mathé, AA; Mikkelsen, JD; Møller, A; Wörtwein, G | 1 |
| Hattiangady, B; Rao, MS; Shetty, AK | 2 |
| Badan, I; Groppa, S; Kessler, C; Patrana, N; Popa-Wagner, A; Walker, L | 1 |
| Li, H; Ren, CP; Wang, L; Yang, H; Yang, XY; Yao, KT; Zhang, HB; Zhao, M | 1 |
| Chai, X; Frotscher, M; Zhao, S | 1 |
| Frielingsdorf, H; Pizzo, DP; Simpson, DR; Thal, LJ | 1 |
| Guilarte, TR; Rohde, CA; Verina, T | 1 |
| Cameron, HA; Cleaver, KM; Olariu, A | 1 |
| Eisch, AJ; Fischer, SJ; Lagace, DC | 1 |
| Harada, S; Kusakabe, Y; Miura, H | 1 |
| Chang, HL; Dombkowski, D; Donahoe, PK; Preffer, F; Szotek, PP; Teixeira, J; Zhang, L | 1 |
| Bartke, A; Sun, LY | 1 |
| Kosec, D; Leposavić, G; Perisić, M; Pesić, V; Pilipović, I; Plećas-Solarović, B; Radojević, K | 1 |
| Beaugié, CR; Fleming, JS; Livingstone, V; McQuillan, HJ; Millier, MJ | 1 |
| Horner, PJ; Inman, DM | 1 |
| Baba, H; Hayashi, A; Hoshi, T; Suzuki, A; Yamaguchi, Y | 1 |
| Enoki, N; Kiyoshima, T; Kobayashi, I; Sakai, H; Sakai, T; Takahashi, K; Terada, Y | 1 |
| Eisch, AJ; Mandyam, CD | 1 |
| Bashir, T; Guzman-Marin, R; McGinty, D; Suntsova, N; Szymusiak, R | 1 |
| Galea, LA; Spritzer, MD | 1 |
| Ikegaya, Y; Koyama, R; Matsuki, N; Muramatsu, R | 1 |
| Ashkenazi, R; Gentry, SN; He, S; Jackson, TL; Kiel, MJ; Kushner, JA; Morrison, SJ; Teta, M | 1 |
| Gaspert, A; Kaissling, B; Le Hir, M; Picard, N; Vogetseder, A; Walch, M | 1 |
| Gould, E; Gross, CG; Kozorovitskiy, Y; Leuner, B | 1 |
| Bachstetter, AD; Bickford, PC; Cole, MJ; Fister, M; Gemma, C; Hudson, C | 1 |
| Estrada, C; Moreno-López, B; Romero-Grimaldi, C | 1 |
| Frankland, PW; Kee, N; Teixeira, CM; Wang, AH | 1 |
| Belluardo, N; Bonomo, A; Di Liberto, V; Frinchi, M; Fuxe, K; Mudo', G | 1 |
| Berezin, V; Bock, E; Borcel, E; Brionne, T; Herrero, AI; Pérez-Alvarez, L; Sandi, C; Varea, E; Venero, C | 1 |
| Chen, F; Cheng, H; Chu, Q; Han, J; Hu, X; Jia, Y; Jiang, Z; Kan, B; Liu, C; Nie, K; Peng, Y; Qu, Y; Tian, Q; Xiao, C; Yu, J; Zhang, X | 1 |
| Antonchuk, J; Bryder, D; Jacobsen, SE; Jensen, CT; Liuba, K; Nygren, JM; Qian, H; Thorén, LA | 1 |
| Harris, DL; Ishino, Y; Joyce, NC; Zhu, C | 1 |
| Beebe, DC; Shui, YB | 1 |
| Buchhold, B; Hamm, A; Kessler, Ch; Mogoanta, L; Popa-Wagner, A; Suofu, Y; Walker, L | 1 |
| Conover, JC; Daniels, SB; Luo, J; Shook, BA | 1 |
| Bonini, SA; Bortolotto, V; Canonico, PL; Crociara, P; Dellarole, A; Denis-Donini, S; Ferrari-Toninelli, G; Francese, MT; Ghi, P; Grilli, M; Memo, M; Orsetti, M; Quadrato, G | 1 |
| Chang, H; Chen, PJ; Liu, JY; Lou, SJ | 1 |
| Clinnin, K; Coleman, JL; Fahrbach, S; Rueppell, O; Ward, KN | 1 |
| Lil'p, IG | 1 |
| Likhachev, AJ; Margison, GP; Tomatis, L | 1 |
| Bickings, CK; Schneider, EL; Sternberg, H | 1 |
| Casazza, BA; Darlington, GJ; Hefton, JM; Weksler, ME | 1 |
| Dutta, S; Fligiel, SE; Hatfield, JS; Kessel, A; Majumdar, AP; Relan, NK; Tureaud, J | 1 |
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| Dawirs, RR; Fei, F; Hildebrandt, K; Teuchert-Noodt, G | 1 |
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8 review(s) available for bromodeoxyuridine and Aging
| Article | Year |
|---|---|
Functional aging and gradual senescence in zebrafish.
Topics: Aging; Animals; Animals, Genetically Modified; Bromodeoxyuridine; Cellular Senescence; Coloring Agents; Female; Humans; Male; Muscles; Poecilia; Reproduction; Telomerase; Telomere; Zebrafish | 2004 |
Epidermal stem cells.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Separation; Cells, Cultured; Epidermal Cells; Epidermis; Epithelial Cells; Flow Cytometry; Humans; Keratinocytes; Models, Biological; Skin; Stem Cell Transplantation; Stem Cells | 2006 |
Cell lineage and differentiation in taste buds.
Topics: Aging; Animals; Antimetabolites; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cell Differentiation; Cell Lineage; Factor IX; Hedgehog Proteins; Mice; Neural Cell Adhesion Molecules; Rats; Stem Cells; Taste Buds | 2006 |
Adult neurogenesis: can analysis of cell cycle proteins move us "Beyond BrdU"?
Topics: Adult; Aging; Biological Assay; Biomarkers; Brain; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Humans; Nerve Tissue Proteins; Neurons | 2007 |
The sole DNA damage induced by bromodeoxyuridine is sufficient for initiation of both aging and carcinogenesis in vivo.
Topics: Aging; Animals; Bromodeoxyuridine; DNA Damage; Female; Longevity; Male; Mice; Neoplasms, Experimental; Rats; Reproduction | 1994 |
[5-Bromo-2'-desoxyuridine: mutagenic, teratogenic and carcinogenic effects, and influence on the aging process].
Topics: Aging; Animals; Bromodeoxyuridine; Carcinogens; Humans; Mutagens; Teratogens | 1993 |
Adult neurogenesis in mammals: an identity crisis.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Division; Central Nervous System; DNA; Humans; Neurons; Thymidine | 2002 |
Cellular replication and aging.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Chromosomes; Cytological Techniques; DNA; Fibroblasts; Lymphocytes | 1979 |
343 other study(ies) available for bromodeoxyuridine and Aging
| Article | Year |
|---|---|
Optimized N-methyl-D-aspartate receptor antagonist exhibits hippocampal proneurogenic effects in aged senescence-accelerated mouse prone 8 mice.
Topics: Aging; Animals; Bromodeoxyuridine; Hippocampus; Mice; Neural Stem Cells; Neurogenesis; Receptors, N-Methyl-D-Aspartate | 2022 |
Measuring Microglial Turnover in the Adult Brain.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Immunohistochemistry; Mice; Mice, Transgenic; Microglia; Nervous System Diseases; Staining and Labeling | 2019 |
Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Cognition; Cognitive Dysfunction; Dentate Gyrus; Doublecortin Protein; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Stroke | 2019 |
Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice.
Topics: Aging; Alopecia; Animals; Bromodeoxyuridine; Cysteamine; DNA, Mitochondrial; Gene Expression; Glucuronidase; Hair; Humans; Klotho Proteins; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Needles; Peptides; Platelet-Rich Plasma; Receptor, IGF Type 1; Ribosomal Proteins; Transplantation, Autologous | 2020 |
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Topics: Aging; Amyotrophic Lateral Sclerosis; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; DNA-Binding Proteins; Gray Matter; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Perilipin-4; Spinal Cord; White Matter | 2021 |
Establishment and characterization of primary astrocyte culture from adult mouse brain.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Brain; Bromodeoxyuridine; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Cellular Reprogramming Techniques; Female; Fluorescent Antibody Technique; Gliosis; Male; Mice, Inbred C57BL; Neurogenesis; Real-Time Polymerase Chain Reaction | 2017 |
Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice.
Topics: Aging; Animals; Antimetabolites; Anxiety; Bromodeoxyuridine; Depression; Doublecortin Domain Proteins; Eating; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Physical Conditioning, Animal; Running; Swimming; Weight Gain | 2013 |
Sexual experience restores age-related decline in adult neurogenesis and hippocampal function.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Female; Hippocampus; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Reaction Time; Recognition, Psychology; Reward; Sexual Behavior, Animal | 2013 |
Serotonin is required for exercise-induced adult hippocampal neurogenesis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Death; Cell Proliferation; Female; Gene Expression Regulation; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurogenesis; Physical Conditioning, Animal; Serotonin; SOXB1 Transcription Factors; Tryptophan Hydroxylase | 2013 |
Cellular and molecular characterization of multipolar Map5-expressing cells: a subset of newly generated, stage-specific parenchymal cells in the mammalian central nervous system.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Shape; Cell Survival; Central Nervous System; Mammals; Mice; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Oligodendroglia; Phenotype; Rabbits; Time Factors | 2013 |
The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb.
Topics: Aging; Algorithms; Animals; Antimetabolites; Behavior, Animal; Blotting, Western; Bromodeoxyuridine; Cell Movement; Dendrites; Immunohistochemistry; Male; Membrane Potentials; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenesis; Olfactory Bulb; Patch-Clamp Techniques; Sensory Thresholds; Smell; Stereotaxic Techniques; Tenascin | 2013 |
Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon.
Topics: Age Factors; Aging; Animals; Animals, Genetically Modified; Brain Injuries; Bromodeoxyuridine; Cell Count; Disease Models, Animal; ELAV Proteins; ELAV-Like Protein 3; Green Fluorescent Proteins; Histones; Nerve Regeneration; Nerve Tissue Proteins; Neural Stem Cells; Neuroglia; Proliferating Cell Nuclear Antigen; S100 Calcium Binding Protein beta Subunit; Telencephalon; Zebrafish; Zebrafish Proteins | 2013 |
Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice.
Topics: Adult Stem Cells; Age Factors; Aging; Amyloid beta-Peptides; Animals; Antigens, CD1; Brain; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Lateral Ventricles; Male; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Peptide Fragments; Phosphatidylinositol 3-Kinases; Signal Transduction; SOXB1 Transcription Factors | 2013 |
Influence of histological degree of seminiferous tubular degeneration and stage of seminiferous cycle on the proliferation of spermatogonia in aged Syrian hamster (Mesocricetus auratus).
Topics: Aging; Animals; Apoptosis; Bromodeoxyuridine; Cell Proliferation; Cricetinae; Male; Mesocricetus; S Phase; Seminiferous Epithelium; Seminiferous Tubules; Spermatogenesis; Spermatogonia | 2014 |
Mechanism of metformin: inhibition of DNA damage and proliferative activity in Drosophila midgut stem cell.
Topics: Aging; Animals; Animals, Genetically Modified; Bromodeoxyuridine; Cell Proliferation; Cellular Senescence; DNA Damage; Drosophila; Female; Green Fluorescent Proteins; Hypoglycemic Agents; Intestines; Male; Metformin; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Stem Cells; Temperature | 2013 |
Effect of ageing on healing of bilateral mandibular condyle fractures in a rat model.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Fracture Fixation, Internal; Fracture Healing; Immunoenzyme Techniques; Male; Mandibular Condyle; Mandibular Fractures; Osteogenesis; Rats; Rats, Sprague-Dawley | 2014 |
Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain.
Topics: Aging; Animals; Appetitive Behavior; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Female; Hippocampus; Immunohistochemistry; Male; Maze Learning; Mice; Microscopy, Fluorescence; Neurogenesis | 2013 |
Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: pathophysiological relevance for Alzheimer's disease?
Topics: Aging; Animals; Apolipoproteins E; Bromodeoxyuridine; Cell Proliferation; Female; Flow Cytometry; Genotype; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Polymorphism, Genetic; Sex Characteristics | 2014 |
Age-related changes in stem cell dynamics, neurogenesis, apoptosis, and gliosis in the adult brain: a novel teleost fish model of negligible senescence.
Topics: Aging; Animals; Apoptosis; Blotting, Western; Brain; Bromodeoxyuridine; Cell Count; Cell Death; Female; Fish Proteins; Gliosis; Gymnotiformes; Immunohistochemistry; Linear Models; Male; Models, Animal; Nerve Tissue Proteins; Neural Stem Cells; Neurogenesis; SOXB1 Transcription Factors | 2014 |
Cell proliferation, movement and differentiation during maintenance of the adult mouse adrenal cortex.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cell Proliferation; Injections; Mice; Mice, Inbred C57BL; Models, Biological; Staining and Labeling; Stem Cells; Steroids | 2013 |
A decrease in the addition of new cells in the nucleus accumbens and prefrontal cortex between puberty and adulthood in male rats.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Male; Neurogenesis; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 2014 |
Age-related differences in oligodendrogenesis across the dorsal-ventral axis of the mouse hippocampus.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cell Count; Cell Survival; Hippocampus; Immunohistochemistry; Male; Mice, Inbred C57BL; Mitosis; Nerve Tissue Proteins; Neural Stem Cells; Neurogenesis; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Receptor, Platelet-Derived Growth Factor alpha | 2014 |
Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.
Topics: Adult Stem Cells; Aging; Animals; Bromodeoxyuridine; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Crosses, Genetic; Cuprizone; Cytokines; Fluorescent Antibody Technique; Mice; Mice, Transgenic; Neural Stem Cells; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase | 2014 |
Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Bromodeoxyuridine; Cell Adhesion Molecules, Neuronal; Cell Line; Dentate Gyrus; Extracellular Matrix Proteins; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Memantine; Mice, Transgenic; Microglia; Nerve Tissue Proteins; Neuroglia; Neuroprotection; Plaque, Amyloid; Presenilin-1; Reelin Protein; Serine Endopeptidases; SOXB1 Transcription Factors | 2015 |
Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors.
Topics: Aging; Analysis of Variance; Animals; Antigens; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cells, Cultured; Central Nervous System; Gene Expression Regulation; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitosis; Nerve Tissue Proteins; Oligodendroglia; Proteoglycans; Receptor, Platelet-Derived Growth Factor alpha; Repressor Proteins; Stem Cells | 2015 |
Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cognition Disorders; Doublecortin Protein; Female; Hippocampus; Male; Maze Learning; Mice; Neurogenesis; Neurons; Phosphopyruvate Hydratase; Recognition, Psychology; Stress, Psychological | 2015 |
Aging attenuates acquired heat tolerance and hypothalamic neurogenesis in rats.
Topics: Aging; Animals; Antigens, Nuclear; Body Temperature; Bromodeoxyuridine; Cell Count; Cell Movement; Cell Survival; Doublecortin Domain Proteins; Hot Temperature; Hypothalamus; Immunohistochemistry; Male; Microscopy, Confocal; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuroglia; Neurons; Neuropeptides; Rats, Wistar | 2015 |
Defects in subventricular zone pigmented epithelium-derived factor niche signaling in the senescence-accelerated mouse prone-8.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Eye Proteins; Lateral Ventricles; Mice; Models, Animal; Models, Neurological; Nerve Growth Factors; Neural Stem Cells; Receptors, Neuropeptide; RNA, Messenger; Serpins; Signal Transduction; Stem Cell Niche | 2015 |
The effects of acute and chronic administration of phosphatidylserine on cell proliferation and survival in the dentate gyrus of adult and middle-aged rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Hippocampus; Immunohistochemistry; Ki-67 Antigen; Male; Memory, Episodic; Memory, Long-Term; Memory, Short-Term; Neuroprotective Agents; Phosphatidylserines; Psychological Tests; Rats, Wistar; Recognition, Psychology; Time Factors | 2015 |
Age-Dependent Netrin-1 Signaling Regulates NG2+ Glial Cell Spatial Homeostasis in Normal Adult Gray Matter.
Topics: Aging; Animals; Antibodies; Antigens; Bromodeoxyuridine; Cell Count; Gray Matter; Homeostasis; Immunoprecipitation; Ki-67 Antigen; Mice, Transgenic; Microscopy, Confocal; Nerve Growth Factors; Netrin-1; Neuroglia; Proliferating Cell Nuclear Antigen; Proteoglycans; Receptor, Platelet-Derived Growth Factor alpha; RNA, Untranslated; Signal Transduction; Tumor Suppressor Proteins | 2015 |
Age-dependent Müller glia neurogenic competence in the mouse retina.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cell Cycle Proteins; Cell Differentiation; Ependymoglial Cells; Epidermal Growth Factor; Gliosis; In Vitro Techniques; Mice; Nerve Tissue Proteins; Neurogenesis; Neurons; Organ Culture Techniques; Retina; Time Factors; Transcription Factors | 2015 |
Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia.
Topics: Aging; Animals; Blood Cells; Brain Infarction; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Movement; Cell Proliferation; Cerebral Cortex; Disease Models, Animal; Doublecortin Protein; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Neurogenesis; Neurons; Neutrophil Infiltration; Phosphopyruvate Hydratase | 2015 |
INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio).
Topics: Aging; Androgens; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Shape; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Humans; Insulin; Male; Protein Transport; Proteins; RNA, Messenger; Sertoli Cells; Spermatogonia; Testis; Zebrafish | 2016 |
Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades.
Topics: Aging; Animals; Astrocytes; Bromodeoxyuridine; Gene Expression Regulation; Hippocampus; Lead; Mice; Mice, Inbred C57BL; Microglia; Myeloid Differentiation Factor 88; Neurons; NF-kappa B; Toll-Like Receptor 4 | 2015 |
proBDNF Attenuates Hippocampal Neurogenesis and Induces Learning and Memory Deficits in Aged Mice.
Topics: Aging; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Female; Hippocampus; Learning Disabilities; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Nerve Tissue Proteins; Neurogenesis; Protein Precursors; Swimming; Time Factors | 2016 |
1,3-Dinitrobenzene neurotoxicity - Passage effect in immortalized astrocytes.
Topics: Adenosine Triphosphate; Aging; Animals; Astrocytes; Bromodeoxyuridine; Cell Line, Transformed; Cell Proliferation; Cells, Cultured; Coculture Techniques; Dinitrobenzenes; Embryo, Mammalian; Glial Fibrillary Acidic Protein; Linear Models; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neurotoxins; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley | 2016 |
Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Nucleus; Cell Proliferation; Cell Shape; Homeostasis; Humans; Mice, Inbred C57BL; Models, Biological; Phagocytosis; Photoreceptor Cells; Retinal Photoreceptor Cell Outer Segment; Retinal Pigment Epithelium; Tubulin; Wound Healing | 2016 |
Effects of Aging on Hippocampal Neurogenesis After Irradiation.
Topics: Aging; Animals; Bromodeoxyuridine; Cranial Irradiation; Hippocampus; Male; Mice; Microglia; Neural Stem Cells; Neurogenesis; Radiation Dosage | 2016 |
Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis.
Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Apoptosis; beta-Galactosidase; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Bromodeoxyuridine; Cell Proliferation; Crosses, Genetic; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Gene Knock-In Techniques; In Situ Nick-End Labeling; Incisor; Linear Models; Male; Mandible; Mice, Inbred C57BL; Molar; Morphogenesis; Organ Size; Phenotype; Staining and Labeling; Tooth; X-Ray Microtomography | 2016 |
Blunted response of hippocampal AMPK associated with reduced neurogenesis in older versus younger mice.
Topics: Adenosine Triphosphate; Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Doublecortin Domain Proteins; Gene Expression Regulation; Hippocampus; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Muscle, Skeletal; Neurogenesis; Neuropeptides; Ribonucleotides | 2016 |
Patterns of olfactory bulb neurogenesis in the adult zebrafish are altered following reversible deafferentation.
Topics: Adult Stem Cells; Aging; Animals; Bromodeoxyuridine; Caspase 3; Cell Movement; Cell Proliferation; Cell Survival; Female; Immunohistochemistry; Male; Models, Animal; Neural Pathways; Neural Stem Cells; Neurogenesis; Neuronal Plasticity; Olfactory Bulb; Zebrafish | 2016 |
Comparative effects of amphetamine-like psychostimulants on rat hippocampal cell genesis at different developmental ages.
Topics: Age Factors; Aging; Amphetamine; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Hippocampus; Ki-67 Antigen; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurogenesis; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C | 2016 |
Sertoli cells are capable of proliferation into adulthood in the transition region between the seminiferous tubules and the rete testis in Wistar rats.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Fluorescent Antibody Technique; GATA4 Transcription Factor; Ki-67 Antigen; Male; Rats, Wistar; Receptors, Androgen; Rete Testis; Seminiferous Tubules; Sertoli Cells; Sexual Maturation | 2016 |
Preventing painful age-related bone fractures: Anti-sclerostin therapy builds cortical bone and increases the proliferation of osteogenic cells in the periosteum of the geriatric mouse femur.
Topics: Adaptor Proteins, Signal Transducing; Aging; Analysis of Variance; Animals; Antibodies; Bone Density; Bromodeoxyuridine; Cell Proliferation; Cortical Bone; Fractures, Bone; Glycoproteins; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Osteogenesis; Pain; Periosteum | 2016 |
Dehydroepiandrosterone increases the number and dendrite maturation of doublecortin cells in the dentate gyrus of middle age male Wistar rats exposed to chronic mild stress.
Topics: Aging; Animals; Antigens, Nuclear; Body Weight; Bromodeoxyuridine; Cell Survival; Chronic Disease; Dehydroepiandrosterone; Dendrites; Dentate Gyrus; Dietary Sucrose; Doublecortin Domain Proteins; Doublecortin Protein; Male; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuropeptides; Psychotropic Drugs; Random Allocation; Rats, Wistar; Stress, Psychological | 2017 |
Studies of HVC Plasticity in Adult Canaries Reveal Social Effects and Sex Differences as Well as Limitations of Multiple Markers Available to Assess Adult Neurogenesis.
Topics: Aging; Animals; Biomarkers; Brain; Bromodeoxyuridine; Canaries; Corticosterone; Deoxyuridine; Doublecortin Domain Proteins; Female; Linear Models; Male; Microtubule-Associated Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Neuropeptides; Sex Characteristics; Social Behavior; Vocalization, Animal | 2017 |
PM
Topics: Administration, Inhalation; Aging; Ammonium Sulfate; Animals; Body Weight; Brain; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Cerebral Ventricles; Dendrites; Doublecortin Domain Proteins; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Particulate Matter; Rats; Rats, Sprague-Dawley | 2017 |
Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Proliferation; Computers; Dentate Gyrus; Hippocampus; Image Cytometry; Mice; Mice, Knockout; Mice, Neurologic Mutants; Neurons; Reproducibility of Results; S Phase; Software; Stem Cells | 2008 |
Apoptotic cell death, long-term persistence, and neuronal differentiation of aneuploid cells generated in the adult brain of teleost fish.
Topics: Aging; Aneuploidy; Animals; Apoptosis; Brain; Bromodeoxyuridine; Caspase 3; Cell Differentiation; Cell Nucleus Shape; Cell Survival; Chromosome Segregation; ELAV Proteins; Female; Fishes; Immunohistochemistry; Male; Mitosis; Neuronal Plasticity; Neurons; Stem Cells; Time Factors | 2008 |
Retardation in somatosensory cortex development induced by postnatal BrdU treatment in mice.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Antimetabolites; Biomarkers; Bromodeoxyuridine; Female; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Interneurons; Male; Mice; Mice, Inbred C57BL; Neuroglia; Somatosensory Cortex; Somatosensory Disorders; Synaptic Transmission | 2008 |
Age-dependent effects of chronic stress on brain plasticity and depressive behavior.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Locomotion; Male; Neurogenesis; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Sucrose; Swimming | 2008 |
A decrease in retinal progenitor cells is associated with early features of diabetic retinopathy in a model that combines diabetes and hypertension.
Topics: Aging; Animals; Blood-Retinal Barrier; Blotting, Western; Bromodeoxyuridine; Capillary Permeability; Cell Count; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Retinopathy; Disease Models, Animal; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Hypertension; In Situ Nick-End Labeling; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Retina; Stem Cells; Time Factors; Vascular Endothelial Growth Factor A | 2008 |
Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen.
Topics: Age Factors; Aging; Animals; Brain; Bromodeoxyuridine; Cardiolipins; Cell Respiration; Cells, Cultured; Electron Transport Complex IV; Embryo, Mammalian; Enzyme Inhibitors; Estradiol; Estrogens; Glutamic Acid; Male; Mitochondria; Neurons; Oxygen Consumption; Potassium Cyanide; Rats; Rats, Inbred F344 | 2009 |
Age-dependent regenerative responses in the striatum and cortex after hypoxia-ischemia.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cerebrum; Chemokine CCL2; Hypoxia-Ischemia, Brain; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Phenotype | 2009 |
The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus.
Topics: Aging; Alzheimer Disease; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Proliferation; Excitatory Amino Acid Antagonists; Hippocampus; Intermediate Filament Proteins; Male; Memantine; Mice; Mice, Inbred C57BL; Nerve Regeneration; Nerve Tissue Proteins; Nestin; Neurogenesis; Neuroglia; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; SOXB1 Transcription Factors; Stem Cells; Up-Regulation | 2009 |
Effects of the hypnotic drug zolpidem on cell proliferation and survival in the dentate gyrus of young and old rats.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Dentate Gyrus; Hypnotics and Sedatives; Immunohistochemistry; Ki-67 Antigen; Male; Neurons; Photomicrography; Pyridines; Rats; Rats, Sprague-Dawley; Sleep; Zolpidem | 2009 |
Ageing abolishes the effects of fluoxetine on neurogenesis.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Brain; Bromodeoxyuridine; Cell Survival; Fluoxetine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurogenesis; Neurons | 2009 |
Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Brain; Bromodeoxyuridine; Castration; Cell Count; Female; Glial Fibrillary Acidic Protein; Male; Neurogenesis; Phosphopyruvate Hydratase; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2008 |
Regional differences in olfactory epithelial homeostasis in the adult mouse.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cell Survival; Forkhead Transcription Factors; Histones; Homeostasis; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurogenesis; Neurons; Olfactory Mucosa; RNA, Messenger | 2009 |
Cellular basis of neurogenesis in the brain of crayfish, Procambarus clarkii: Neurogenic complex in the olfactory midbrain from hatchlings to adults.
Topics: Aging; Animals; Astacoidea; Brain; Bromodeoxyuridine; Cell Division; Immunohistochemistry; Interneurons; Mesencephalon; Neurogenesis; Neurons; Olfactory Pathways | 2009 |
Fibroblast growth factor 2-stimulated proliferation is lower in muscle precursor cells from old rats.
Topics: Adult Stem Cells; Aging; Animals; Base Sequence; Bromodeoxyuridine; Cell Proliferation; DNA Primers; Fibroblast Growth Factor 2; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Muscle Fibers, Skeletal; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; RNA, Messenger; Signal Transduction | 2009 |
Adult neurogenesis in the crayfish brain: proliferation, migration, and possible origin of precursor cells.
Topics: Aging; Animals; Astacoidea; Blotting, Western; Brain; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cell Proliferation; Female; Glutamate-Ammonia Ligase; Immunohistochemistry; Male; Neurogenesis; Stem Cell Niche; Stem Cells | 2009 |
Age-dependent spatial distribution of bromodeoxyuridine-immunoreactive cells in the main olfactory bulb.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Immunohistochemistry; Male; Odorants; Olfactory Bulb; Rats; Rats, Wistar; Sexual Behavior, Animal; Thymidine | 2009 |
Age-related myelin dynamics revealed by increased oligodendrogenesis and short internodes.
Topics: Aging; Animals; Autophagy-Related Proteins; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Efferent Pathways; Female; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Nerve Tissue Proteins; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Ranvier's Nodes; Red Nucleus; Spinal Cord | 2009 |
Effect of postnatal methamphetamine trauma and adolescent methylphenidate treatment on adult hippocampal neurogenesis in gerbils.
Topics: Administration, Oral; Aging; Animals; Bromodeoxyuridine; Dentate Gyrus; Gerbillinae; Hippocampus; Injections; Methamphetamine; Methylphenidate; Neurogenesis; Sodium Chloride; Time Factors | 2009 |
Increased neuronal proliferation in the dentate gyrus of aged rats following neural stem cell implantation.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Line; Cell Proliferation; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Humans; Immunohistochemistry; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Rats; Rats, Inbred F344; Stem Cell Transplantation; Stem Cells; Transplantation, Heterologous | 2010 |
Prozac during puberty: distinctive effects on neurogenesis as a function of age and sex.
Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Corticosterone; Female; Fluoxetine; Male; Neurogenesis; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sexual Maturation; Time Factors | 2009 |
Comparative study of regenerative potential of beta cells from young and aged donor mice using a novel islet transplantation model.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Diabetes Mellitus, Experimental; Hyperglycemia; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Ki-67 Antigen; Male; Mice; Models, Animal; Regeneration; Transplantation, Isogeneic | 2009 |
Influence of aging on chondroitin sulfate proteoglycan expression and neural stem/progenitor cells in rat brain and improving effects of a herbal medicine, yokukansan.
Topics: Aggrecans; Aging; Animals; Brain; Bromodeoxyuridine; Cell Movement; Cell Proliferation; Cognition Disorders; Drugs, Chinese Herbal; Hippocampus; Male; Nerve Regeneration; Neuronal Plasticity; Neurons; Neuroprotective Agents; Prefrontal Cortex; Rats; Recovery of Function; Stem Cells; Treatment Outcome | 2009 |
Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Benzoxazines; Bromodeoxyuridine; Cannabinoids; Doublecortin Domain Proteins; Drug Administration Schedule; Drug Delivery Systems; Hippocampus; Male; Microtubule-Associated Proteins; Morpholines; Naphthalenes; Neurogenesis; Neurons; Neuropeptides; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344 | 2009 |
Decreased cytogenesis in the granule cell layer of the hippocampus and impaired place learning after irradiation of the young mouse brain evaluated using the IntelliCage platform.
Topics: Aging; Animals; Body Weight; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Hippocampus; Learning; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Neuropsychological Tests; Random Allocation; Space Perception; Time Factors | 2010 |
Enhanced neurogenesis in the olfactory bulb in adult mice after injury induced by acute treatment with trimethyltin.
Topics: Adult Stem Cells; Aging; Animals; Astrocytes; Brain; Bromodeoxyuridine; Cell Count; Cell Movement; Cells, Cultured; Male; Mice; Neurogenesis; Neurons; Neurotoxins; Olfactory Bulb; Stem Cell Niche; Time Factors; Trimethyltin Compounds | 2010 |
Age-related effects on hippocampal precursor cell subpopulations and neurogenesis.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Doublecortin Domain Proteins; Green Fluorescent Proteins; Hippocampus; In Situ Nick-End Labeling; Indoles; Intermediate Filament Proteins; Learning Curve; Maze Learning; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neural Stem Cells; Neurogenesis; Neuropeptides; Statistics, Nonparametric; Time Factors | 2011 |
Changes in cell proliferation in the subventricular zone of the brain in adult rats given beta-amyloid peptide (25-35).
Topics: Aging; Amyloid beta-Peptides; Animals; Bromodeoxyuridine; Cell Proliferation; Dentate Gyrus; Immunohistochemistry; Male; Peptide Fragments; Protein Multimerization; Rats; Rats, Wistar; Stem Cell Niche; Time Factors | 2010 |
Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cytological Techniques; Dentate Gyrus; Deoxyuridine; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Physical Conditioning, Animal; Random Allocation; Restraint, Physical; Staining and Labeling; Stress, Psychological | 2010 |
Cardiomyocyte cell cycle control and growth estimation in vivo--an analysis based on cardiomyocyte nuclei.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Cycle; Cell Nucleus; Cell Proliferation; Cell Separation; Cells, Cultured; DNA Replication; Flow Cytometry; Gene Expression Regulation, Developmental; Gestational Age; Green Fluorescent Proteins; Immunohistochemistry; Ki-67 Antigen; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mitosis; Myocytes, Cardiac; Polyploidy; Reverse Transcriptase Polymerase Chain Reaction; Troponin T | 2010 |
Quantitative analysis of postnatal neurogenesis and neuron number in the macaque monkey dentate gyrus.
Topics: Aging; Animals; Antimetabolites; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Cell Size; Dentate Gyrus; Female; Humans; In Situ Nick-End Labeling; Ki-67 Antigen; Macaca mulatta; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurogenesis; Phenotype; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2010 |
Potential of Macrostomum lignano to recover from gamma-ray irradiation.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Compartmentation; Cell Proliferation; Dose-Response Relationship, Radiation; Gamma Rays; Gene Expression Regulation, Developmental; Regeneration; Stem Cells; Survival Analysis; Turbellaria | 2010 |
Brief spatial experiences increase granule cell survival in the dentate gyrus of adult rats.
Topics: Aging; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Survival; Dentate Gyrus; Exploratory Behavior; Male; Neurogenesis; Neurons; Random Allocation; Rats; Rats, Long-Evans; Space Perception; Time Factors | 2010 |
Slow age-dependent decline of doublecortin expression and BrdU labeling in the forebrain from lesser hedgehog tenrecs.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Cell Differentiation; Doublecortin Domain Proteins; Doublecortin Protein; Eulipotyphla; Female; Fluorescent Antibody Technique; Immunoenzyme Techniques; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Prosencephalon; Time Factors | 2010 |
Deafferentation enhances neurogenesis in the young and middle aged hippocampus but not in the aged hippocampus.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Fluorescent Antibody Technique; Humans; Kainic Acid; Male; Microtubule-Associated Proteins; Models, Animal; Neural Stem Cells; Neurogenesis; Neurons; Neuropeptides; Rats; Rats, Inbred F344 | 2011 |
Cell cycle dynamics of NG2 cells in the postnatal and ageing brain.
Topics: Age Factors; Aging; Animals; Antigens; Brain; Bromodeoxyuridine; Cell Count; Cell Cycle; Estrogen Antagonists; Gene Expression Regulation, Developmental; Luminescent Proteins; Mice; Mice, Transgenic; Oligodendroglia; Proteoglycans; Receptor, Platelet-Derived Growth Factor alpha; Tamoxifen | 2009 |
To proliferate or not to proliferate.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Cycle; Cell Lineage; Cell Nucleus; Cell Proliferation; Cell Separation; DNA Replication; Flow Cytometry; Gene Expression Regulation, Developmental; Humans; Immunohistochemistry; Ki-67 Antigen; Kinetics; Myocytes, Cardiac; Polyploidy; Troponin T | 2010 |
Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation, and cell death.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Death; Cell Differentiation; Cell Proliferation; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Olfactory Marker Protein; Olfactory Mucosa; Olfactory Receptor Neurons | 2010 |
Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating.
Topics: Adolescent; Adult; Aged; Aging; Bromodeoxyuridine; Cell Proliferation; Female; Humans; Insulin-Secreting Cells; Male; Middle Aged; Radiometric Dating; Staining and Labeling; Thymidine; Tissue Donors; Young Adult | 2010 |
Visualizing lens epithelial cell proliferation in whole lenses.
Topics: Aging; Animals; Antibodies; Bromodeoxyuridine; Cell Proliferation; Epithelial Cells; Fluorescence; Imaging, Three-Dimensional; Lens, Crystalline; Mice; S Phase; Staining and Labeling | 2010 |
Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus.
Topics: Aging; Animals; Antibody Specificity; Blotting, Western; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Dentate Gyrus; Fluorescent Antibody Technique; Interneurons; Male; Mice; Mice, Inbred C57BL; Neurons; Organ Specificity; Stem Cells; Time Factors; Tryptophan Oxygenase | 2010 |
FGF-2/FGFR1 neurotrophic system expression level and its basal activation do not account for the age-dependent decline of precursor cell proliferation in the subventricular zone of rat brain.
Topics: Adult Stem Cells; Aging; Animals; Brain; Bromodeoxyuridine; Cell Proliferation; Cerebral Ventricles; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Gene Expression Regulation; Male; Mitogen-Activated Protein Kinase 3; Neurogenesis; Phospholipase C gamma; Phosphorylation; Rats; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; RNA, Messenger | 2010 |
Novel neurogenesis drugs uncovered from in vivo chemical library screen.
Topics: Aging; Animals; Bromodeoxyuridine; Humans; Membrane Proteins; Mice; Mice, Knockout; Neurodegenerative Diseases; Neurogenesis; Small Molecule Libraries | 2010 |
Cell proliferative activity in the kidney of young growing rat analyzed using flash and cumulative labeling with bromodeoxyuridine.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Female; Immunohistochemistry; Kidney; Rats; Rats, Sprague-Dawley; Staining and Labeling; Toxicity Tests | 2010 |
Mammary gland proliferation in female rats: effects of the estrous cycle, pseudo-pregnancy and age.
Topics: Age Factors; Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Estrous Cycle; Female; Ki-67 Antigen; Mammary Glands, Animal; Proliferating Cell Nuclear Antigen; Pseudopregnancy; Rats; Rats, Sprague-Dawley | 2012 |
Chronic treatment with fluoxetine for more than 6 weeks decreases neurogenesis in the subventricular zone of adult mice.
Topics: Aging; Animals; Bromodeoxyuridine; Calbindins; Cell Count; Cell Proliferation; Cerebral Ventricles; Dentate Gyrus; DNA-Binding Proteins; Fluoxetine; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurogenesis; Nuclear Proteins; Olfactory Bulb; S100 Calcium Binding Protein G; Time Factors | 2011 |
When are new hippocampal neurons, born in the adult brain, integrated into the network that processes spatial information?
Topics: Aging; Animals; Bromodeoxyuridine; Cell Movement; Cell Survival; Dentate Gyrus; Hippocampus; Longevity; Male; Models, Biological; Nerve Net; Neurons; Rats; Rats, Wistar; Space Perception; Time Factors | 2011 |
Novel control by the CA3 region of the hippocampus on neurogenesis in the dentate gyrus of the adult rat.
Topics: Aging; Animals; Bromodeoxyuridine; CA3 Region, Hippocampal; Calbindins; Cell Count; Cell Proliferation; Cell Survival; Dentate Gyrus; Fluoxetine; Ibotenic Acid; Male; Mitosis; Neural Stem Cells; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Staining and Labeling; Time Factors | 2011 |
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice.
Topics: Aging; Amygdala; Animals; Bromodeoxyuridine; Cell Count; Cell Line; Cell Lineage; Cell Proliferation; Electrophysiological Phenomena; Environment; Mice; Microglia; Motor Activity; Nerve Growth Factors; Neurogenesis; Neurons; Oligodendroglia; Phenotype; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Visual Cortex | 2011 |
Neurons generated in senescence maintain capacity for functional integration.
Topics: Aging; Analysis of Variance; Animals; Bromodeoxyuridine; Cytoskeletal Proteins; Dentate Gyrus; Hippocampus; Learning; Microscopy, Confocal; Nerve Net; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Rats; Rats, Inbred F344 | 2012 |
Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice.
Topics: Aging; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Fluorescent Antibody Technique; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred BALB C; Microglia; Neurogenesis; Neurons; Phenotype; Physical Conditioning, Animal; Running | 2012 |
LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's disease.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Bromodeoxyuridine; Cell Proliferation; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Fatty Acids, Unsaturated; Humans; Learning; Male; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Muscle Strength; Mutation; Plaque, Amyloid; Polyphenols; Postural Balance; Reaction Time; Reflex; Sensory Gating | 2012 |
Age-related decline in label-retaining tubular cells: implication for reduced regenerative capacity after injury in the aging kidney.
Topics: Aging; Animals; Bromodeoxyuridine; Cells, Cultured; Coculture Techniques; Endothelial Cells; Gene Expression Regulation; Humans; Kidney; Male; Rats; Rats, Wistar; Regeneration; Reperfusion Injury; Staining and Labeling; Stem Cells | 2012 |
Age-related proteomic changes in the subventricular zone and their association with neural stem/progenitor cell proliferation.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Proliferation; Cerebral Ventricles; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Male; Nerve Tissue Proteins; Nestin; Neural Stem Cells; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2012 |
Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.
Topics: Aging; Animals; Astrocytes; Bromodeoxyuridine; Cell Count; Cell Movement; Cell Proliferation; Cell Survival; Dopamine; Dopaminergic Neurons; Doublecortin Domain Proteins; Glial Fibrillary Acidic Protein; Interneurons; Lateral Ventricles; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neostriatum; Neurogenesis; Neuropeptides; Olfactory Bulb; Oxidopamine | 2012 |
Repeat estradiol exposure differentially regulates protein expression patterns for estrogen receptor and E-cadherin in older mouse ovarian surface epithelium: implications for replacement and adjuvant hormone therapies?
Topics: Adjuvants, Pharmaceutic; Aging; Animals; Bromodeoxyuridine; Cadherins; Cell Size; Epithelium; Estradiol; Female; Gene Expression Regulation; Hormone Replacement Therapy; Mice; Organ Size; Ovary; Protein Transport; Receptors, Estrogen; Time Factors; Uterus | 2012 |
Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cardiomyopathy, Dilated; Cardiovascular Abnormalities; Cell Proliferation; Chromosomal Proteins, Non-Histone; Costameres; Fibrosis; Gene Deletion; Gene Expression Profiling; Heart; Integrases; Mice; Mice, Knockout; Microfilament Proteins; Microtubules; Myocytes, Cardiac; Organ Specificity; Protein Binding; Transcription, Genetic; Troponin T | 2012 |
Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cyclin D2; Dentate Gyrus; Doublecortin Domain Proteins; In Situ Nick-End Labeling; Ki-67 Antigen; Kinetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides | 2012 |
Environmental enrichment restores neurogenesis and rapid acquisition in aged rats.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Antigens; Bromodeoxyuridine; Cell Count; Cues; Doublecortin Domain Proteins; Environment; Glial Fibrillary Acidic Protein; Hippocampus; Male; Maze Learning; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Phosphopyruvate Hydratase; Proteoglycans; Psychomotor Performance; Rats; Rats, Inbred F344; Spatial Behavior; Time Factors | 2013 |
Determinants of central nervous system adult neurogenesis are sex, hormones, mouse strain, age, and brain region.
Topics: Adult Stem Cells; Aging; Animals; Bromodeoxyuridine; Central Nervous System; Estrous Cycle; Female; Hormones; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurogenesis; Platelet-Derived Growth Factor; Sex Characteristics; Species Specificity | 2013 |
Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Differentiation; Cytokines; Drinking; Gene Expression; Hippocampus; Male; Maze Learning; Mice; Microfilament Proteins; Microglia; Minocycline; Neurogenesis; Phosphopyruvate Hydratase; Time Factors | 2013 |
Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Death; Cell Differentiation; Cell Division; Cell Movement; Cell Survival; Dendrites; Lateral Ventricles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Olfaction Disorders; Olfactory Bulb; Smell; Stem Cells | 2002 |
Seizure induced dentate neurogenesis does not diminish with age in rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Dentate Gyrus; Excitatory Amino Acid Agonists; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Neurons; Rats; Rats, Wistar; Seizures | 2002 |
Survival of fetal hippocampal CA3 cell grafts in the middle-aged and aged hippocampus: effect of host age and deafferentation.
Topics: Age Factors; Aging; Animals; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Cell Survival; Fetal Tissue Transplantation; Graft Survival; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Rats; Rats, Inbred F344 | 2002 |
Aging and developmental transitions in the B cell lineage.
Topics: Aging; Animals; B-Lymphocytes; Bone Marrow; Bromodeoxyuridine; Cell Differentiation; Cellular Senescence; Female; Flow Cytometry; Kinetics; Mice; Mice, Inbred BALB C; Spleen; Staining and Labeling | 2002 |
Proliferative activity and expression of cyclin-dependent kinase inhibitor p21WAF1 and p53 protein in endothelial cells of human aorta during replicative aging in vitro.
Topics: Adult; Aging; Aorta; beta-Galactosidase; Bromodeoxyuridine; Cell Division; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Endothelium, Vascular; Humans; Immunohistochemistry; In Vitro Techniques; Reactive Oxygen Species; Time Factors; Tumor Suppressor Protein p53 | 2002 |
Adaptive response and the influence of ageing: effects of low-dose irradiation on cell growth of cultured glial cells.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Female; Mice; Mice, Knockout; Mice, SCID; Neuroglia; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Signal Transduction; Time Factors; X-Rays | 2002 |
Mouse epidermal stem cells proceed through the cell cycle.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p57; Epidermal Cells; Epidermis; Flow Cytometry; G1 Phase; G2 Phase; Mice; Mice, Inbred ICR; Mitosis; Nuclear Proteins; Resting Phase, Cell Cycle; S Phase; Stem Cells | 2003 |
Estradiol initially enhances but subsequently suppresses (via adrenal steroids) granule cell proliferation in the dentate gyrus of adult female rats.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aging; Animals; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Estradiol; Female; Growth Inhibitors; Hydrocortisone; Ovariectomy; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Chronic lithium enhances hippocampal long-term potentiation, but not neurogenesis, in the aged rat dentate gyrus.
Topics: Aging; Animals; Bromodeoxyuridine; Cells, Cultured; Dentate Gyrus; Kinetics; Lithium; Long-Term Potentiation; Male; Neurons; Rats; Rats, Sprague-Dawley; Stem Cells | 2003 |
EGF and NGF injected into the brain of old mice enhance BDNF and ChAT in proliferating subventricular zone.
Topics: Acetylcholine; Aging; Animals; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Division; Choline O-Acetyltransferase; Drug Interactions; Drug Therapy, Combination; Epidermal Growth Factor; Immunohistochemistry; Ki-67 Antigen; Male; Mice; Nerve Growth Factor; Neurons; RNA, Messenger; Stem Cells; Up-Regulation | 2003 |
Effect of age and testosterone on autumnal neurogenesis in male European starlings (Sturnus vulgaris).
Topics: Aging; Analysis of Variance; Animals; Brain Mapping; Bromodeoxyuridine; Cell Division; Immunohistochemistry; Male; Neuronal Plasticity; Neurons; Radioactive Tracers; Seasons; Songbirds; Telencephalon; Testis; Testosterone; Tissue Distribution; Vocalization, Animal | 2003 |
The zebrafish as a vertebrate model of functional aging and very gradual senescence.
Topics: Aging; Animals; beta-Galactosidase; Biomarkers; Bromodeoxyuridine; Cell Division; Lipofuscin; Models, Animal; Muscles; Oxidation-Reduction; Poecilia; Proteins; Skin; Species Specificity; Telomerase; Vertebrates; Zebrafish | 2003 |
Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline.
Topics: Aging; Animals; Antimetabolites; Behavior, Animal; Bromodeoxyuridine; Cognition; Dentate Gyrus; Immunohistochemistry; Male; Maze Learning; Neurons; Rats; Rats, Long-Evans | 2003 |
Common mechanisms for declines in oxidative stress tolerance and proliferation with aging.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Division; Cell Survival; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Free Radicals; Hepatocytes; Hydrogen Peroxide; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Time Factors | 2003 |
Effects of chronic furosemide treatment and age on cell division in the adult gerbil inner ear.
Topics: Action Potentials; Aging; Animals; Bromodeoxyuridine; Cell Division; Cochlea; Differential Threshold; Drug Administration Schedule; Ear, Inner; Furosemide; Gerbillinae; Histocytochemistry; Hydrogen Peroxide; Immunologic Techniques; Melanins; Oxidants; Round Window, Ear; Staining and Labeling | 2003 |
Disruption of postnatal progenitor migration and consequent abnormal pattern of glial distribution in the cerebrum following administration of methylmercury.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Bromodeoxyuridine; Cell Count; Cell Movement; Cerebellum; Glial Fibrillary Acidic Protein; Kidney; Liver; Methylmercury Compounds; Nerve Growth Factors; Neuroglia; Neurons; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stem Cells; Telencephalon; Tissue Distribution | 2003 |
Steroidogenic acute regulatory protein in the rat brain: cellular distribution, developmental regulation and overexpression after injury.
Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Brain Injuries; Bromodeoxyuridine; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Kainic Acid; Male; Neurons; Phosphoproteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2003 |
Hoxa11 regulates stromal cell death and proliferation during neonatal uterine development.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Bromodeoxyuridine; Cell Cycle; Cell Division; Female; Gene Deletion; Homeodomain Proteins; Homozygote; Mice; Mice, Knockout; Stromal Cells; Uterus | 2004 |
Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss.
Topics: Acetyltransferases; Adaptor Proteins, Signal Transducing; Aging; Animals; Animals, Newborn; Axons; Behavior, Animal; Blotting, Western; Bromodeoxyuridine; Carrier Proteins; Cell Count; Cell Death; ErbB Receptors; Ganglia, Spinal; Gene Expression Regulation, Developmental; Glial Cell Line-Derived Neurotrophic Factor; Glycoproteins; Homozygote; Hyperalgesia; Immunohistochemistry; In Situ Nick-End Labeling; Lectins; Membrane Proteins; Mice; Mice, Transgenic; Microscopy, Electron; Myelin Sheath; Nerve Growth Factors; Neuregulin-1; Neurofilament Proteins; Neurons, Afferent; Oncogene Proteins v-fos; Pain Measurement; Reaction Time; Receptor, ErbB-4; Receptor, trkA; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Schwann Cells; Sciatic Nerve; Signal Transduction; Spinal Cord; Trans-Activators; Transcription Factors | 2003 |
Transient expression of doublecortin during adult neurogenesis.
Topics: Aging; Animals; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Central Nervous System; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Antibody Technique; Hippocampus; Lateral Ventricles; Microtubule-Associated Proteins; Mitosis; Neurons; Neuropeptides; Olfactory Bulb; Rats; Rats, Wistar; Stem Cells; Time Factors | 2003 |
Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Hippocampus; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Spatial Behavior | 2003 |
Generation of retinal ganglion cells is modulated by caspase-dependent programmed cell death.
Topics: Aging; Animals; Apoptosis; Axons; Bromodeoxyuridine; Caspase 3; Caspases; Cell Adhesion Molecules, Neuron-Glia; Cell Count; Cell Division; Chick Embryo; Cysteine Proteinase Inhibitors; Drug Interactions; Homeodomain Proteins; Immunohistochemistry; In Situ Nick-End Labeling; LIM-Homeodomain Proteins; Nerve Tissue Proteins; Neurons; Retinal Ganglion Cells; Thymidine; Time Factors; Transcription Factors; Tritium; Tubulin | 2003 |
Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys.
Topics: Acoustic Stimulation; Aging; Animals; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyrus; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Exploratory Behavior; Female; Hippocampus; Hydrocortisone; Macaca mulatta; Male; Motor Activity; Phosphopyruvate Hydratase; Pregnancy; Prenatal Exposure Delayed Effects; Stress, Physiological | 2003 |
B lymphocyte development in rabbit: progenitor B cells and waning of B lymphopoiesis.
Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; B-Lymphocyte Subsets; Base Sequence; Bone Marrow Cells; Bromodeoxyuridine; Cell Differentiation; Gene Rearrangement, B-Lymphocyte, Light Chain; Hematopoietic Stem Cells; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Immunoglobulin Light Chains, Surrogate; Immunoglobulin Variable Region; Lymphopoiesis; Membrane Glycoproteins; Mice; Molecular Sequence Data; Pre-B Cell Receptors; Rabbits; Receptors, Antigen, B-Cell; Sequence Homology, Amino Acid | 2003 |
Expression and function of orphan nuclear receptor TLX in adult neural stem cells.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Gene Deletion; Gene Expression Regulation, Developmental; Gene Silencing; Intermediate Filament Proteins; Mice; Multipotent Stem Cells; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Prosencephalon; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Stem Cells | 2004 |
Age-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Down-Regulation; Exercise Test; Male; Neuronal Plasticity; Neurons; Physical Exertion; Rats; Rats, Sprague-Dawley; Stem Cells | 2004 |
Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex.
Topics: Aging; Animals; Bromodeoxyuridine; Calbindins; Cell Adhesion Molecules, Neuronal; Embryo, Mammalian; Extracellular Matrix Proteins; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neocortex; Nerve Tissue Proteins; Neurons; Proliferating Cell Nuclear Antigen; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Reelin Protein; S100 Calcium Binding Protein G; Serine Endopeptidases; Tubulin | 2004 |
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.
Topics: Administration, Oral; Aging; Animals; Antigens, Differentiation; Bromodeoxyuridine; Cell Count; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; Deoxyuridine; Glial Fibrillary Acidic Protein; Idoxuridine; Intermediate Filament Proteins; Lateral Ventricles; Male; Mice; Minichromosome Maintenance Complex Component 2; Nerve Tissue Proteins; Nestin; Neurons; Nuclear Proteins; Stem Cells | 2004 |
Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors.
Topics: Acetylcholinesterase; Aging; Animals; Brain Tissue Transplantation; Bromodeoxyuridine; Calbindins; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Corpus Striatum; Embryo, Mammalian; Female; Ibotenic Acid; Immunohistochemistry; Mitosis; Neurons; Phosphopyruvate Hydratase; Pregnancy; Rats; S100 Calcium Binding Protein G; Stem Cells; Time Factors; Transplants | 2004 |
Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb.
Topics: Abnormalities, Drug-Induced; Aging; Aldehyde Oxidoreductases; Animals; Animals, Newborn; Body Patterning; Bromodeoxyuridine; Carcinoma; Cell Death; Cell Differentiation; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic Induction; Extremities; Female; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Galactosides; Gene Expression Regulation, Developmental; High Mobility Group Proteins; Homeodomain Proteins; In Situ Hybridization; In Situ Nick-End Labeling; Indoles; Limb Buds; Male; Mesoderm; Mice; Mice, Knockout; Models, Biological; Pregnancy; Retinoic Acid 4-Hydroxylase; SOX9 Transcription Factor; Time Factors; Trans-Activators; Transcription Factors; Transfection; Tretinoin | 2004 |
Vitamin E affects cell death in adult rat dentate gyrus.
Topics: Aging; Animals; Apoptosis; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyrus; In Situ Nick-End Labeling; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E; Vitamin E Deficiency | 2003 |
A transgenic marker for newly born granule cells in dentate gyrus.
Topics: Action Potentials; Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Division; Cell Movement; Dentate Gyrus; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Cell Adhesion Molecule L1; Neurons; Physical Exertion; Pro-Opiomelanocortin; Promoter Regions, Genetic; Sialic Acids; Transgenes | 2004 |
Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice.
Topics: Aging; Animals; Astrocytes; Biomarkers; Bromodeoxyuridine; Caloric Restriction; Cell Differentiation; Cell Division; Cell Survival; Dentate Gyrus; Down-Regulation; Food Deprivation; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Stem Cells | 2004 |
Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Axons; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Differentiation; Cell Polarity; Cell Size; Cell Survival; Cells, Cultured; Corpus Callosum; Dendrites; Embryo, Mammalian; Female; Fibroblast Growth Factor 2; Flow Cytometry; Functional Laterality; Immunohistochemistry; Male; Mice; Mice, Knockout; Neocortex; Neurofilament Proteins; Neurons; Neurotrophin 3; Polymerase Chain Reaction; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Time Factors | 2004 |
Sex differences in adult suprachiasmatic nucleus neurons emerging late prenatally in rats.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Arginine Vasopressin; Bromodeoxyuridine; Calbindin 1; Calbindins; Cell Count; Embryo, Mammalian; Female; Geniculate Bodies; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neurons; Neuropeptide Y; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Sex Characteristics; Suprachiasmatic Nucleus; Testosterone Propionate | 2004 |
Inhibition of growth and differentiation of osteoprogenitors in mouse bone marrow stromal cell cultures by increased donor age and glucocorticoid treatment.
Topics: Aging; Alkaline Phosphatase; Animals; Bone and Bones; Bone Marrow Cells; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dexamethasone; Glucocorticoids; Mice; Mice, Inbred C57BL; Osteoblasts; Stem Cells; Stromal Cells | 2004 |
Neurogenesis in a rat model of age-related cognitive decline.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Survival; Cognition; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Male; Maze Learning; Nerve Tissue Proteins; Neurons; Rats; Rats, Long-Evans | 2004 |
Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice.
Topics: Aging; Animals; B-Lymphocytes; Bone Marrow; Bromodeoxyuridine; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation; Immunity, Cellular; Mice; Mice, Inbred Strains; Time Factors; VDJ Recombinases | 2004 |
The renal papilla is a niche for adult kidney stem cells.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Culture Techniques; Cell Division; Flow Cytometry; Ischemia; Kidney Medulla; Mice; Rats; Rats, Sprague-Dawley; Renal Circulation; Stem Cells | 2004 |
Aging influences cellular and molecular responses of apoptosis to skeletal muscle unloading.
Topics: Aging; Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Blotting, Western; Bromodeoxyuridine; Flavoproteins; Fluorescent Antibody Technique; Hindlimb Suspension; Hypertrophy; In Situ Nick-End Labeling; Membrane Proteins; Muscle, Skeletal; Proto-Oncogene Proteins c-bcl-2; Quail; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice.
Topics: Aging; Animals; Antimetabolites; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cognition; Coloring Agents; Dentate Gyrus; Disease Models, Animal; DNA Primers; Dwarfism; Enzyme-Linked Immunosorbent Assay; Genotype; Growth Hormone; Hippocampus; Insulin-Like Growth Factor I; Longevity; Mice; Mice, Mutant Strains; Microscopy, Fluorescence; Neurons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Up-Regulation | 2005 |
Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain.
Topics: Aging; Animals; Brain Ischemia; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Dentate Gyrus; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lateral Ventricles; Male; Neurons; Rats; Rats, Inbred F344 | 2004 |
Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene Bax.
Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cell Proliferation; Dentate Gyrus; Hippocampus; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Proto-Oncogene Proteins c-bcl-2 | 2004 |
Increased cell proliferation and neurogenesis in the hippocampal dentate gyrus of old GFAP(-/-)Vim(-/-) mice.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Proliferation; Dentate Gyrus; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neurons; Vimentin | 2004 |
Newly born cells in the ageing dentate gyrus display normal migration, survival and neuronal fate choice but endure retarded early maturation.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Enlargement; Cell Movement; Cell Survival; Dendrites; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Gene Expression Regulation; Immunohistochemistry; Male; Microtubule-Associated Proteins; Neurons; Neuropeptides; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344; Stem Cells; Time Factors | 2005 |
In vivo and in vitro neurogenesis in human olfactory epithelium.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antigens, Differentiation; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Shape; Cells, Cultured; Humans; Immunohistochemistry; Middle Aged; Nerve Tissue Proteins; Neurons; Olfactory Marker Protein; Olfactory Mucosa; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Stem Cells | 2005 |
Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus.
Topics: Aging; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Proliferation; Cross Reactions; Dentate Gyrus; Idoxuridine; Male; Mice; Mice, Inbred C57BL; Staining and Labeling | 2005 |
Hippocampal neurogenesis is not enhanced by lifelong reduction of glucocorticoid levels.
Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Apoptosis; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Dentate Gyrus; Down-Regulation; Glucocorticoids; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Regeneration; Stem Cells | 2005 |
Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Endothelium, Vascular; Immunohistochemistry; Male; Neovascularization, Pathologic; Neuronal Plasticity; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sodium Chloride; Stroke; Sulfones; Synapses; Synaptophysin; Time Factors; Treatment Outcome | 2005 |
Hippocampal neurogenesis and PSA-NCAM expression following exposure to 56Fe particles mimics that seen during aging in rats.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Dentate Gyrus; Hippocampus; Iron; Male; Microscopy, Electron, Scanning; Neural Cell Adhesion Molecule L1; Radiation, Ionizing; Rats; Rats, Sprague-Dawley; Sialic Acids; Whole-Body Irradiation | 2005 |
Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Dentate Gyrus; Female; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Lead; Long-Term Potentiation; Male; Maze Learning; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Time Factors | 2005 |
[Age-related changes in renewal of taste bud cells and expression of taste cell-specific proteins in mice].
Topics: Aging; Animals; Bromodeoxyuridine; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Taste Buds; Transducin; Ubiquitin Thiolesterase | 2005 |
Estradiol and soy extract increase the production of new cells in the dentate gyrus of old rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Dentate Gyrus; Estradiol; Female; Glycine max; Phytoestrogens; Plant Extracts; Rats; Rats, Wistar | 2005 |
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Cell Cycle; Cell Death; DNA Fragmentation; Humans; Mice; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Neurofibrillary Tangles; Neurons; Protein Isoforms; tau Proteins | 2005 |
Thyroid hormone regulates hippocampal neurogenesis in the adult rat brain.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Cognition Disorders; Down-Regulation; Hippocampus; Hyperthyroidism; Hypothyroidism; Male; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Stem Cells; Thyroid Hormones; Thyroxine; Triiodothyronine | 2005 |
Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress.
Topics: Adrenal Glands; Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Count; Hippocampus; Linear Models; Neurons; Organ Size; Stress, Psychological; Tupaiidae | 2005 |
Lifelong corticosterone level determines age-related decline in neurogenesis and memory.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Bromodeoxyuridine; Cell Count; Corticosterone; Immunohistochemistry; Ki-67 Antigen; Male; Maze Learning; Memory Disorders; Models, Biological; Neurons; Organ Size; Organogenesis; Rats; Rats, Sprague-Dawley; Reaction Time; Statistics as Topic; Stereotaxic Techniques; Stress, Physiological | 2006 |
Dynamics of neurogenesis in the dentate gyrus of adult rats.
Topics: Aging; Animals; Animals, Newborn; Biomarkers; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Count; Cell Differentiation; Cell Division; Cell Proliferation; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Male; Microtubule-Associated Proteins; Neurons; Neuropeptides; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Stroke-induced neurogenesis in aged brain.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Cerebral Arteries; Dentate Gyrus; Female; Hippocampus; Immunohistochemistry; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ischemia; Ki-67 Antigen; Microscopy, Confocal; Microscopy, Fluorescence; Neurons; Rats; Rats, Wistar; Stem Cells; Stroke; Time Factors | 2005 |
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection | 2005 |
Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Bromodeoxyuridine; Cell Count; Cell Proliferation; Dentate Gyrus; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Immunohistochemistry; Ki-67 Antigen; Male; Methylazoxymethanol Acetate; Microtubule-Associated Proteins; Motor Activity; Neurons; Neuropeptides; Protein Synthesis Inhibitors; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2005 |
Age-related naturally occurring depression of hippocampal neurogenesis does not affect trace fear conditioning.
Topics: Aging; Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Conditioning, Operant; Electroshock; Fear; Hippocampus; Male; Microscopy, Confocal; Neurons; Rats; Rats, Sprague-Dawley | 2006 |
The effects of repeated corticosteroid administration on the neurogenesis in the neonatal rat.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Bromodeoxyuridine; Cell Proliferation; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunohistochemistry; Mitosis; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Rats; Rats, Sprague-Dawley | 2006 |
Accelerated delimitation of the infarct zone by capillary-derived nestin-positive cells in aged rats.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Glial Fibrillary Acidic Protein; Imaging, Three-Dimensional; Immunohistochemistry; Infarction, Middle Cerebral Artery; Intermediate Filament Proteins; Laminin; Male; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Neuropeptides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2006 |
New striatal dopamine neurons in MPTP-treated macaques result from a phenotypic shift and not neurogenesis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamate Decarboxylase; Interneurons; Macaca; Male; MPTP Poisoning; Nerve Regeneration; Phenotype; Tyrosine 3-Monooxygenase | 2006 |
A decreased survival of proliferated cells in the hippocampus is associated with a decline in spatial memory in aged rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Conditioning, Psychological; Fear; Hippocampus; Immunohistochemistry; Male; Memory; Rats; Spatial Behavior | 2006 |
Lesion-induced neurogenesis in the hypothalamus is involved in behavioral recovery in adult ring doves.
Topics: Aging; Animals; Biomarkers; Brain Injuries; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Columbidae; Denervation; Female; Hypothalamus; Male; Necrosis; Nerve Degeneration; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Recovery of Function; Sexual Behavior, Animal; Stem Cells; Ventromedial Hypothalamic Nucleus | 2006 |
The aging hippocampus: a multi-level analysis in the rat.
Topics: Aging; Animals; Behavior, Animal; Bromodeoxyuridine; Discrimination, Psychological; Doublecortin Domain Proteins; Doublecortin Protein; Female; Hippocampus; Immunohistochemistry; Ki-67 Antigen; Magnetic Resonance Imaging; Maze Learning; Microtubule-Associated Proteins; Multivariate Analysis; Neuropeptides; Phosphopyruvate Hydratase; Positron-Emission Tomography; Rats; Rats, Inbred F344; Spatial Behavior | 2006 |
Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats.
Topics: Aging; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Chromatography, High Pressure Liquid; Electrochemistry; Environment; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Male; Microdialysis; Neurons; Rats; Rats, Wistar; Reaction Time | 2006 |
A hierarchy of proliferative cells exists in mouse lens epithelium: implications for lens maintenance.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Proliferation; Epithelial Cells; Female; Lens, Crystalline; Mice; Mice, Inbred BALB C; Pregnancy; Stem Cells; Thymidine | 2006 |
A Pituitary cell type coexpressing messenger ribonucleic acid of proopiomelanocortin and the glycoprotein hormone alpha-subunit in neonatal rat and chicken: rapid decline with age and reappearance in vitro under regulatory pressure of corticotropin-releas
Topics: Aging; Animals; Animals, Newborn; Antimetabolites; Bromodeoxyuridine; Cells, Cultured; Chickens; Corticotropin-Releasing Hormone; Female; Flow Cytometry; Fluorescent Antibody Technique; Glycoprotein Hormones, alpha Subunit; Paraffin Embedding; Pituitary Gland; Pro-Opiomelanocortin; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Early-life fluoxetine exposure reduced functional deficits after hypoxic-ischemia brain injury in rat pups.
Topics: Aging; Animals; Animals, Newborn; Antimetabolites; Blotting, Western; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Female; Fluoxetine; Hippocampus; Hypoxia-Ischemia, Brain; Locomotion; Male; Maze Learning; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Size; Phosphorylation; Psychomotor Performance; Rats; Reverse Transcriptase Polymerase Chain Reaction; Selective Serotonin Reuptake Inhibitors; Synapsins | 2006 |
Neocortical neurogenesis in humans is restricted to development.
Topics: Aged; Aged, 80 and over; Aging; Animals; Antimetabolites; Atmosphere; Autopsy; Bromodeoxyuridine; Carbon Radioisotopes; Humans; Middle Aged; Neocortex; Nuclear Warfare; Stem Cells; Time Factors | 2006 |
A decrease of cell proliferation by hypothermia in the hippocampus of the neonatal rat.
Topics: Aging; Animals; Animals, Newborn; Asphyxia Neonatorum; Biomarkers; Body Temperature; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Dentate Gyrus; Disease Models, Animal; Doublecortin Domain Proteins; Down-Regulation; Hippocampus; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Microtubule-Associated Proteins; Neurons; Neuropeptides; Rats; Rats, Sprague-Dawley; Stem Cells | 2006 |
Gene expression and proliferation analysis in young, aged, and osteoarthritic sheep chondrocytes effect of growth factor treatment.
Topics: Aggrecans; Aging; Animals; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Chondrocytes; Collagen Type II; Disease Models, Animal; Gene Expression; Intercellular Signaling Peptides and Proteins; Osteoarthritis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep; Transforming Growth Factor beta | 2006 |
Less neurogenesis and inflammation in the immature than in the juvenile brain after cerebral hypoxia-ischemia.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Dentate Gyrus; DNA-Binding Proteins; Hippocampus; Hypoxia-Ischemia, Brain; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroglia; Neurons; Nuclear Proteins | 2007 |
Age-related changes in cell density and the proliferation rate of olfactory ensheathing cells in the lamina propria of postnatal mouse olfactory mucosa.
Topics: Aging; Animals; Animals, Newborn; Antimetabolites; Axons; Bromodeoxyuridine; Cell Count; Cell Proliferation; Female; Immunohistochemistry; Kinetics; Mice; Mice, Inbred ICR; Microscopy, Electron; Olfactory Mucosa; Olfactory Nerve; Tissue Fixation | 2006 |
Mammary carcinogenesis is preceded by altered epithelial cell turnover in transforming growth factor-alpha and c-myc transgenic mice.
Topics: Aging; Animals; Apoptosis; Bromodeoxyuridine; Cell Proliferation; Epithelial Cells; Epithelium; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins c-myc; Transforming Growth Factor alpha | 2006 |
Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus.
Topics: Aging; Animals; Astrocytes; Bromodeoxyuridine; Capillaries; Cell Count; Cell Proliferation; Cerebral Ventricles; DNA-Binding Proteins; Doublecortin Protein; Hippocampus; HMGB Proteins; Ki-67 Antigen; Male; Nerve Tissue Proteins; Neurons; Rats; Rats, Inbred F344; Rec A Recombinases; SOXB1 Transcription Factors; Stem Cells; Transcription Factors; Vimentin | 2008 |
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression?
Topics: Aging; Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Survival; Depression; Hippocampus; Immunohistochemistry; Nerve Fibers; Neuronal Plasticity; Neurons; Neuropeptide Y; Presynaptic Terminals; Rats; Rats, Inbred Strains; Serotonin | 2006 |
The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Cell Survival; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Immunohistochemistry; Ki-67 Antigen; Male; Microtubule-Associated Proteins; Models, Biological; Neurons; Neuropeptides; Rats; Rats, Inbred F344; Stem Cells; Telencephalon | 2006 |
Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats.
Topics: Aging; Analysis of Variance; Animals; Apoptosis; Blood Vessels; Brain Infarction; Bromodeoxyuridine; Cell Count; Fluoresceins; Imaging, Three-Dimensional; In Situ Nick-End Labeling; Ischemic Attack, Transient; Male; Nerve Tissue Proteins; Neuroglia; Neurons; Organic Chemicals; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors | 2007 |
Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Bromodeoxyuridine; Carcinoma; Cell Line, Transformed; Cell Line, Tumor; Epithelial Cells; Female; Humans; Immunohistochemistry; Isotope Labeling; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Nude; Nasopharyngeal Neoplasms; Nasopharynx; Neoplasm Transplantation; Stem Cells; Thymidine; Transplantation, Heterologous | 2007 |
Balance between neurogenesis and gliogenesis in the adult hippocampus: role for reelin.
Topics: Aging; Animals; Astrocytes; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Doublecortin Domain Proteins; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Neuronal Plasticity; Neurons; Neuropeptides; Reelin Protein; Stem Cells | 2007 |
Nerve growth factor promotes survival of new neurons in the adult hippocampus.
Topics: Aging; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Cell Death; Cell Differentiation; Cell Proliferation; Cell Survival; Choline O-Acetyltransferase; Dentate Gyrus; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Male; Nerve Growth Factor; Neurons; Rats; Rats, Inbred F344 | 2007 |
Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats.
Topics: Aging; Animals; Brain; Bromodeoxyuridine; Doublecortin Protein; Environmental Exposure; Female; Hippocampus; Lead Poisoning; Nerve Fibers; Neurons; Phenotype; Rats; Rats, Inbred Lew | 2007 |
Decreased neurogenesis in aged rats results from loss of granule cell precursors without lengthening of the cell cycle.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Cycle; Cell Death; Cell Differentiation; Doublecortin Protein; Male; Neurons; Organogenesis; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Stem Cells | 2007 |
Gender and endogenous levels of estradiol do not influence adult hippocampal neurogenesis in mice.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Estradiol; Estrous Cycle; Female; Fluoxetine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurons; Ovariectomy; Selective Serotonin Reuptake Inhibitors; Sex Characteristics; Sex Factors; Species Specificity; Stem Cells | 2007 |
Adult mouse myometrial label-retaining cells divide in response to gonadotropin stimulation.
Topics: Adipocytes; Aging; Animals; Bacterial Proteins; beta Catenin; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Proliferation; Chorionic Gonadotropin; Female; Humans; Integrases; Luminescent Proteins; Mice; Myocytes, Smooth Muscle; Myometrium; Phenotype; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Stromal Cells | 2007 |
Adult neurogenesis in the hippocampus of long-lived mice during aging.
Topics: Actins; Aging; Animals; Apoptosis; Autoradiography; bcl-Associated Death Protein; Bromodeoxyuridine; Cell Proliferation; Cognition; Dentate Gyrus; Disease Models, Animal; Dwarfism; Hippocampus; Insulin-Like Growth Factor I; Longevity; Mice; Mice, Mutant Strains; Neurons; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Signal Transduction | 2007 |
Long-term beta-adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Annexins; Antigens, Surface; Antimetabolites; Apoptosis; Bromodeoxyuridine; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cell Proliferation; Flow Cytometry; Fluorescent Antibody Technique; Immunoconjugates; Interleukin-2 Receptor alpha Subunit; Ki-67 Antigen; Lymphocyte Count; Male; Organ Size; Rats; Rats, Wistar; T-Lymphocyte Subsets; Thy-1 Antigens; Thymus Gland | 2007 |
E-cadherin expression and bromodeoxyuridine incorporation during development of ovarian inclusion cysts in age-matched breeder and incessantly ovulated CD-1 mice.
Topics: Aging; Androstenedione; Animals; Apoptosis; Breeding; Bromodeoxyuridine; Cadherins; Cyst Fluid; Epithelium; Estradiol; Female; Immunoblotting; Immunochemistry; Mice; Mice, Inbred Strains; Osmolar Concentration; Ovarian Cysts; Ovary; Ovulation; Species Specificity; Testosterone | 2007 |
Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma.
Topics: Aging; Animals; Astrocytes; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Division; Cell Proliferation; Chronic Disease; Disease Models, Animal; Glaucoma; Glial Fibrillary Acidic Protein; Gliosis; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microglia; Neuroglia; Retina; Retinal Degeneration; RNA, Messenger; Up-Regulation | 2007 |
Differential inductions of small heat shock protein 27 and 1-Cys peroxiredoxin in reactive astrocytes in sulfatide-deficient mouse spinal cord.
Topics: Aging; Animals; Antimetabolites; Astrocytes; Blotting, Western; Bromodeoxyuridine; Connexin 43; Connexins; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Immunohistochemistry; Mass Spectrometry; Mice; Mice, Knockout; Mice, Neurologic Mutants; Oligodendroglia; Peroxidases; Peroxiredoxins; Spinal Cord; Sulfoglycosphingolipids; Sulfotransferases; Up-Regulation | 2007 |
Age-dependent changes in cell proliferation and cell death in the periodontal tissue and the submandibular gland in mice: a comparison with other tissues and organs.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Death; Cell Proliferation; Epithelial Cells; Gingiva; In Situ Nick-End Labeling; Kidney; Kinetics; Liver; Mice; Mouth Mucosa; Organ Specificity; Periodontium; Skin; Submandibular Gland | 2007 |
Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat.
Topics: Adrenalectomy; Age Factors; Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corticosterone; Dentate Gyrus; Down-Regulation; Exercise Test; Ki-67 Antigen; Male; Neuronal Plasticity; Neurons; Phenotype; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Sleep Wake Disorders; Stem Cells; Stress, Psychological; Wakefulness | 2007 |
Testosterone and dihydrotestosterone, but not estradiol, enhance survival of new hippocampal neurons in adult male rats.
Topics: Aging; Animals; Bromodeoxyuridine; Castration; Cell Differentiation; Cell Proliferation; Cell Survival; Dentate Gyrus; Dihydrotestosterone; Estrogens; Hippocampus; Male; Neuronal Plasticity; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Stem Cells; Testosterone | 2007 |
Neonatally born granule cells numerically dominate adult mice dentate gyrus.
Topics: Aging; Animals; Animals, Newborn; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Dentate Gyrus; Female; Homeodomain Proteins; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Sex Characteristics; Stem Cells; Tumor Suppressor Proteins | 2007 |
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.
Topics: Aging; Animals; Animals, Newborn; Bone Marrow Cells; Bromodeoxyuridine; Cells, Cultured; Chromosome Segregation; Cyclophosphamide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Mice; Stochastic Processes; Time Factors | 2007 |
Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells.
Topics: Age Factors; Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Epithelial Cells; G1 Phase; Humans; Ki-67 Antigen; Kidney Tubules, Proximal; Male; Mitogens; Organometallic Compounds; Rats; Rats, Wistar; Regeneration; Stem Cells; Time Factors | 2008 |
Diminished adult neurogenesis in the marmoset brain precedes old age.
Topics: Aging; Animals; Biomarkers; Brain; Bromodeoxyuridine; Callithrix; Dentate Gyrus; DNA; Female; Male; Neurons; Organogenesis | 2007 |
Blockade of caspase-1 increases neurogenesis in the aged hippocampus.
Topics: Age Factors; Aging; Amino Acid Chloromethyl Ketones; Animals; Bromodeoxyuridine; Caspase 1; Cell Count; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Male; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344; Time Factors; Tubulin | 2007 |
Age-dependent effect of nitric oxide on subventricular zone and olfactory bulb neural precursor proliferation.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Glutathione; Green Fluorescent Proteins; Lateral Ventricles; Mice; NADPH Dehydrogenase; Neural Cell Adhesion Molecule L1; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Olfactory Bulb; Sialic Acids; Stem Cells | 2008 |
Imaging activation of adult-generated granule cells in spatial memory.
Topics: Aging; Animals; Bromodeoxyuridine; Hippocampus; Immunohistochemistry; Maze Learning; Memory; Mice; Neurons; Space Perception; Staining and Labeling; Time Factors | 2007 |
Nicotine-induced fibroblast growth factor-2 restores the age-related decline of precursor cell proliferation in the subventricular zone of rat brain.
Topics: Adult Stem Cells; Aging; Analysis of Variance; Animals; Antibodies; Brain; Bromodeoxyuridine; Cell Count; Cell Proliferation; Fibroblast Growth Factor 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Lateral Ventricles; Male; Nerve Tissue Proteins; Nestin; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar | 2008 |
Chronic stress in adulthood followed by intermittent stress impairs spatial memory and the survival of newborn hippocampal cells in aging animals: prevention by FGL, a peptide mimetic of neural cell adhesion molecule.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Chronic Disease; Dentate Gyrus; Hippocampus; Immunohistochemistry; Indicators and Reagents; Male; Maze Learning; Memory Disorders; Molecular Mimicry; Neural Cell Adhesion Molecules; Neurons; Rats; Rats, Wistar; Stress, Psychological | 2008 |
Acupuncture improves cognitive deficits and regulates the brain cell proliferation of SAMP8 mice.
Topics: Acupuncture; Aging; Animals; Bromodeoxyuridine; Cell Movement; Cell Proliferation; Cognition Disorders; Dentate Gyrus; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Mice; Mice, Neurologic Mutants; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Stem Cells; Treatment Outcome | 2008 |
Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age.
Topics: Adult Stem Cells; Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Survival; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Kainic Acid; Microtubule-Associated Proteins; Neurons; Neuropeptides; Rats; Rats, Inbred F344; Stem Cells | 2008 |
Kit regulates maintenance of quiescent hematopoietic stem cells.
Topics: Aging; Animals; Bone Marrow Cells; Bromodeoxyuridine; Cell Cycle; Fetus; Hematopoiesis; Hematopoietic Stem Cells; Kinetics; Liver; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Multipotent Stem Cells; Pigmentation; Point Mutation; Proto-Oncogene Proteins c-kit; Resting Phase, Cell Cycle | 2008 |
Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells.
Topics: Adolescent; Aged; Aging; Blotting, Western; Bromodeoxyuridine; Cells, Cultured; Cornea; Cytoplasm; Endothelium, Corneal; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; In Vitro Techniques; Middle Aged; Protein Tyrosine Phosphatase, Non-Receptor Type 1; S Phase; Tissue Distribution | 2008 |
Age-dependent control of lens growth by hypoxia.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Proliferation; Epithelial Cells; Hyperoxia; Hypoxia; In Situ Nick-End Labeling; Lens, Crystalline; Organ Size; Oxygen; Rats | 2008 |
Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats.
Topics: Aging; Animals; Behavior, Animal; Brain; Brain Infarction; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Environment; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Male; Maze Learning; Motor Activity; Multivariate Analysis; Neurologic Examination; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recovery of Function; Time Factors | 2007 |
Subventricular zone-mediated ependyma repair in the adult mammalian brain.
Topics: Adult Stem Cells; Age Factors; Aging; Animals; Astrocytes; Brain; Bromodeoxyuridine; Cell Count; Dose-Response Relationship, Drug; Ependyma; Lateral Ventricles; Male; Mice; Microscopy, Confocal; Microscopy, Electron; Nerve Tissue Proteins; Neuraminidase | 2008 |
Impaired adult neurogenesis associated with short-term memory defects in NF-kappaB p50-deficient mice.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Cell Survival; Hippocampus; Learning; Male; Memory Disorders; Memory, Short-Term; Mice; Mice, Knockout; Neurons; NF-kappa B p50 Subunit; Stem Cells | 2008 |
Hippocampal neurogenesis and gene expression depend on exercise intensity in juvenile rats.
Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Exercise Test; Gene Expression Regulation, Developmental; Hippocampus; Male; Neuronal Plasticity; Neurons; Physical Conditioning, Animal; Physical Exertion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stem Cells; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Age, caste, and behavior determine the replicative activity of intestinal stem cells in honeybees (Apis mellifera L.).
Topics: Aging; Animals; Apoptosis; Bees; Behavior, Animal; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Female; Flight, Animal; Hierarchy, Social; Intestines; Male; Microscopy, Confocal; Nesting Behavior; Social Behavior; Social Dominance; Stem Cells | 2008 |
[Effect of mouse age and genotype on the frequency of sister chromatid exchange in bone marrow cells].
Topics: Aging; Animals; Bone Marrow; Bromodeoxyuridine; Chromosome Aberrations; Crossing Over, Genetic; Genotype; Male; Mice; Mice, Inbred C57BL; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1984 |
Incorporation and persistence of 5-bromodeoxyuridine in newborn rat tissue DNA.
Topics: Aging; Animals; Animals, Newborn; Brain; Bromodeoxyuridine; Carbon Radioisotopes; DNA; DNA Replication; Intestines; Kidney; Kinetics; Liver; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1983 |
Aging and sister chromatid exchange. VII. Effect of aging on background SCE in vivo.
Topics: Aging; Animals; Bone Marrow; Bromodeoxyuridine; Crossing Over, Genetic; DNA Replication; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Strains; Sister Chromatid Exchange | 1982 |
Immunologic studies of aging. V. Impaired proliferation of PHA responsive human lymphocytes in culture.
Topics: Aging; Bromodeoxyuridine; Cell Cycle; Cell Division; Cells, Cultured; Chromatids; Colchicine; Humans; Lymphocytes; Metaphase; Phytohemagglutinins; Thymidine | 1980 |
Increased expression of pp60c-src in gastric mucosa of aged rats.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Gastric Mucosa; Gene Expression; Membrane Proteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Inbred F344; RNA | 1994 |
Differentiation and growth of muscle in the fish Sparus aurata (L): II. Hyperplastic and hypertrophic growth of lateral muscle from hatching to adult.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Hyperplasia; Hypertrophy; Immunohistochemistry; Indicators and Reagents; Larva; Microscopy, Electron; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; Perciformes | 1995 |
Effect of aging on the rat condylar fracture model evaluated by bromodeoxyuridine immunohistochemistry.
Topics: Aging; Animals; Bone Regeneration; Bromodeoxyuridine; Cell Division; Fracture Healing; Immunohistochemistry; Male; Mandibular Condyle; Mandibular Fractures; Rats; Rats, Sprague-Dawley | 1995 |
Striatal TGF-alpha: postnatal developmental expression and evidence for a role in the proliferation of subependymal cells.
Topics: Aging; Animals; Animals, Newborn; Brain; Bromodeoxyuridine; Cell Division; Cerebral Ventricles; Corpus Striatum; ErbB Receptors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; RNA, Messenger; Thymidine; Transforming Growth Factor alpha | 1995 |
Caloric restriction: conservation of in vivo cellular replicative capacity accompanies life-span extension in mice.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Cycle; Cell Division; Cells, Cultured; Energy Intake; Food Deprivation; Longevity; Male; Mice | 1995 |
Birth times of neurons in labellar taste sensilla of the blowfly Phormia regina.
Topics: Aging; Animals; Axons; Bromodeoxyuridine; Diptera; Horseradish Peroxidase; Immunohistochemistry; Metamorphosis, Biological; Neurons, Afferent; Pupa; Sense Organs; Taste | 1995 |
Effect of aging and interval between primary and secondary treatment in carcinogenesis induced by neonatal exposure to 5-bromodeoxyuridine and subsequent administration of N-nitrosomethylurea in rats.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Carcinogens; Cocarcinogenesis; Female; Male; Methylnitrosourea; Pregnancy; Rats | 1995 |
Cell cycle progression in gentamicin-damaged avian cochleas.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Cycle; Chick Embryo; Chickens; Cochlea; Gentamicins; Immunohistochemistry; Microscopy, Electron, Scanning; Proliferating Cell Nuclear Antigen; Protein Biosynthesis; Proteins; Time Factors | 1995 |
Distinguishing normal and glucocorticoid-induced maturation of intestine using bromodeoxyuridine.
Topics: Adrenalectomy; Aging; alpha-Glucosidases; Animals; Animals, Newborn; Animals, Suckling; Bromodeoxyuridine; Cell Differentiation; Glucocorticoids; Intestines; Rats; Rats, Sprague-Dawley; Reference Values | 1995 |
Effects of chronic electrical stimulation on myosin heavy chain expression in satellite cell cultures derived from rat muscles of different fiber-type composition.
Topics: Aging; Animals; Blotting, Northern; Bromodeoxyuridine; Cells, Cultured; Electric Stimulation; Gene Expression; Immunoblotting; Immunohistochemistry; In Situ Hybridization; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosins; Rats; Rats, Wistar; RNA Probes; RNA, Messenger | 1994 |
Developmental regulation of M-cadherin in the terminal differentiation of skeletal myoblasts.
Topics: Aging; Animals; Animals, Newborn; Base Sequence; Bromodeoxyuridine; Cadherins; Cell Differentiation; Cell Line; Mice; Molecular Sequence Data; Muscle Development; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Effects of glibenclamide on pancreatic beta-cell proliferation in vivo.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cell Nucleus; Cell Size; Female; Glyburide; Immunohistochemistry; Islets of Langerhans; Mice; Pancreas; Weight Gain | 1994 |
Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain.
Topics: Aging; Animals; Animals, Newborn; Antigens, Neoplasm; Base Sequence; Blotting, Northern; Brain; Bromodeoxyuridine; DNA Topoisomerases, Type II; DNA-Binding Proteins; In Situ Hybridization; Isoenzymes; Molecular Sequence Data; Oligonucleotide Probes; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution | 1994 |
Effect of aging on neurotensin-stimulated growth of rat small intestine.
Topics: Aging; Animals; Bromodeoxyuridine; Disaccharidases; Eating; Immunohistochemistry; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Neurotensin; Rats; Rats, Inbred F344 | 1994 |
Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cerebral Ventricles; Embryonic and Fetal Development; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurons; Telencephalon; Tubulin | 1994 |
Early expression of the glycoprotein hormone alpha-subunit in the pars tuberalis of the rat pituitary gland during ontogenesis.
Topics: Aging; Animals; Antibody Specificity; Bromodeoxyuridine; Female; Follicle Stimulating Hormone; Glycoproteins; Hypothalamo-Hypophyseal System; Immunohistochemistry; In Situ Hybridization; Luteinizing Hormone; Pituitary Gland, Anterior; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Thyrotropin | 1993 |
Aging diminishes gastric mucosal regeneration: relationship to tyrosine kinases.
Topics: Aged; Aging; Animals; Bromodeoxyuridine; Cell Division; Epithelial Cells; Epithelium; Gastric Mucosa; Humans; Incidence; Membrane Proteins; Ornithine Decarboxylase; Parietal Cells, Gastric; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Regeneration; Sodium Chloride; Stomach Ulcer; Time Factors | 1994 |
Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans.
Topics: Adult; Aging; Animals; Autoradiography; Bromodeoxyuridine; Cell Division; Cells, Cultured; DNA Replication; Epithelial Cells; Epithelium; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Humans; Neomycin; Regeneration; Saccule and Utricle; Thymidine | 1993 |
Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Aging; Animals; Bromodeoxyuridine; Deoxyguanosine; DNA; Intestinal Neoplasms; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Splenic Neoplasms; Thymus Neoplasms; Tongue Neoplasms | 1993 |
Sequence in DNA synthetic phase ratio of spontaneous hypertensive rat (SHR) myocardium--study on development of cardiomegaly.
Topics: Aging; Animals; Blood Pressure; Bromodeoxyuridine; Cardiomegaly; DNA; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; S Phase; Systole | 1993 |
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Movement; Dentate Gyrus; Female; Immunohistochemistry; Neural Cell Adhesion Molecules; Neurons; Polysaccharides; Rats; Rats, Inbred F344; Sialic Acids; Stem Cells | 1996 |
Immune cell proliferation in the harderian gland: an avian model.
Topics: Aging; Animals; B-Lymphocytes; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Chickens; Coculture Techniques; Flow Cytometry; Harderian Gland; Isotope Labeling; Lymphokines; Plasma Cells | 1996 |
Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat.
Topics: Aging; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Male; Mitotic Index; Papilloma; Rats; Rats, Sprague-Dawley; Reference Values; S Phase; Time Factors; Weaning; Zinc | 1996 |
Neonatal exposure of rats to recombinant follicle stimulating hormone increases adult Sertoli and spermatogenic cell numbers.
Topics: Aging; Androgens; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Follicle Stimulating Hormone; Inhibins; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Seminiferous Tubules; Sertoli Cells; Sperm Count; Spermatogenesis; Testis | 1996 |
Morphological changes in the oesophagus of newborn pigs: effects of age, diet and oral insulin-like growth factor I (IGF-I) or IGF-II.
Topics: Administration, Oral; Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Bromodeoxyuridine; Cattle; Epithelium; Esophagus; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Swine | 1996 |
Long-term caloric restriction delays age-related decline in proliferation capacity of murine lens epithelial cells in vitro and in vivo.
Topics: Aging; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Division; Cells, Cultured; Diet; DNA; DNA Replication; Energy Intake; Epithelial Cells; Epithelium; Immunoenzyme Techniques; Lens, Crystalline; Longitudinal Studies; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1997 |
Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Crosses, Genetic; Cyclic AMP; Drosophila Proteins; Embryonic Induction; Female; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Hedgehog Proteins; In Situ Hybridization; Insect Hormones; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurons; Protein Biosynthesis; Proteins; Receptors, Cell Surface; Retina; Stem Cells; Trans-Activators; Transcription, Genetic; Transforming Growth Factor alpha | 1997 |
Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Dominance-Subordination; Hydrocortisone; Male; Neurons; Phosphopyruvate Hydratase; Receptors, N-Methyl-D-Aspartate; Social Behavior; Stress, Psychological; Tupaiidae; Vimentin | 1997 |
Proliferation in the rat olfactory epithelium: age-dependent changes.
Topics: Aging; Animals; Body Weight; Bromodeoxyuridine; Cell Count; Cell Division; Cellular Senescence; Epithelial Cells; Female; Functional Laterality; Male; Olfactory Receptor Neurons; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1997 |
Overload-induced C-Myc oncoprotein is reduced in aged skeletal muscle.
Topics: Aging; Animals; Blotting, Western; Body Weight; Bromodeoxyuridine; Coturnix; Immunohistochemistry; Muscle, Skeletal; Organ Size; Proto-Oncogene Proteins c-myc; Stress, Mechanical; Tissue Distribution | 1997 |
Proliferation and migration kinetics of stem cells in the rat fundic gland.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cell Movement; Evaluation Studies as Topic; Gastric Fundus; Gastric Mucosa; Immunohistochemistry; Lectins; Plant Lectins; Rats; Rats, Wistar; Stem Cells | 1997 |
Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy.
Topics: Aging; Alanine; Alkaline Phosphatase; Ammonia; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Diet; Epithelial Cells; Glutamic Acid; Glutamine; Immunosuppression Therapy; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Random Allocation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tacrolimus; Time Factors; Transplantation, Homologous | 1997 |
Analysis of aberrant neuronal migrations in the hereditary cerebellar vermis defect (CVD) rat using bromodeoxyuridine immunohistochemistry.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Aggregation; Cell Movement; Cerebellar Diseases; Cerebellopontine Angle; Cerebellum; Immunohistochemistry; Neurons; Purkinje Cells; Rats; Rats, Mutant Strains | 1998 |
Supporting cell proliferation in the olfactory epithelium decreases postnatally.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Division; Epithelial Cells; Female; Functional Laterality; Immunohistochemistry; Male; Olfactory Mucosa; Rats; Rats, Sprague-Dawley | 1998 |
No-new-neurons dogma loses ground.
Topics: Aging; Animals; Bromodeoxyuridine; Callithrix; Cell Division; Dentate Gyrus; Humans; Macaca mulatta; Male; Neurons; Stress, Physiological | 1998 |
Experience-induced neurogenesis in the senescent dentate gyrus.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyrus; DNA; Female; Immunohistochemistry; Maze Learning; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Nerve Tissue; Neurons; Phenotype | 1998 |
Hair follicle elongation in organ culture of skin from newborn and adult mice.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Hair Follicle; Insulin; Mice; Mice, Inbred C3H; Minoxidil; Organ Culture Techniques; Skin Physiological Phenomena | 1998 |
Early weaning induces jejunal ornithine decarboxylase and cell proliferation in neonatal rats.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Antimetabolites; Body Weight; Bromodeoxyuridine; Cell Division; Corticosterone; Jejunum; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Sucrase; Weaning | 1998 |
Proliferation in the vomeronasal organ of the rat during postnatal development.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Division; Epithelial Cells; Female; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sex Factors; Smell; Vomeronasal Organ | 1999 |
Embryonic and postnatal injections of bromodeoxyuridine produce age-dependent morphological and behavioral abnormalities.
Topics: Abnormalities, Drug-Induced; Aging; Animals; Animals, Newborn; Behavior, Animal; Behavioral Symptoms; Brain; Bromodeoxyuridine; Drug Administration Schedule; Embryo, Mammalian; Injections; Rats; Rats, Long-Evans | 1999 |
B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation.
Topics: Aging; Animals; B-Lymphocytes; Bone Marrow Cells; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Lineage; Cell Survival; Immunoglobulin M; Lymphocyte Activation; Mice; Receptors, Antigen, B-Cell; Spleen; Stem Cells | 1999 |
Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory.
Topics: Aging; Animals; Antimetabolites; Astrocytes; Biomarkers; Bromodeoxyuridine; Calbindin 1; Calbindins; Cell Division; Dentate Gyrus; Environment; Female; Glial Fibrillary Acidic Protein; Memory; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Space Perception; Stem Cells | 1999 |
Estrogen and progesterone stimulate Schwann cell proliferation in a sex- and age-dependent manner.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Estrogens; Female; Immunohistochemistry; Male; Progesterone; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Sex Factors; Thymidine | 1999 |
A single neonatal dose of methamphetamine suppresses dentate granule cell proliferation in adult gerbils which is restored to control values by acute doses of haloperidol.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Gerbillinae; Haloperidol; Male; Methamphetamine; Reference Values | 1999 |
Rapid extension of axons into the CA3 region by adult-generated granule cells.
Topics: Aging; Animals; Axons; Bromodeoxyuridine; Cell Count; Dentate Gyrus; Fluorescent Dyes; Hippocampus; Immunohistochemistry; Male; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Restoring production of hippocampal neurons in old age.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Division; Cell Survival; DNA; Hippocampus; Neurons; Rats; Rats, Sprague-Dawley | 1999 |
Age-dependent changes in the distribution of BrdU- and TUNEL-positive cells in the murine gingival tissue.
Topics: Aging; Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Cell Count; Cell Death; Cell Division; Cell Movement; Cellular Senescence; Connective Tissue Cells; Disease Susceptibility; Epithelial Attachment; Epithelial Cells; Gingiva; Gingival Recession; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred C3H; Mouth Mucosa | 1999 |
Neurogenesis in the neocortex of adult primates.
Topics: Aging; Animals; Astrocytes; Axons; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Movement; Cell Survival; Female; Lateral Ventricles; Macaca fascicularis; Male; Microscopy, Confocal; Neocortex; Neurons; Parietal Lobe; Prefrontal Cortex; Temporal Lobe; Visual Cortex | 1999 |
5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species.
Topics: Aging; Animals; Biomarkers; Bromodeoxyuridine; Cell Cycle; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Mice; Polymorphism, Restriction Fragment Length; Telomere; Tumor Cells, Cultured | 1999 |
Age-related changes in the hamster epididymis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cricetinae; Cytoplasm; Epididymis; Male; Sperm Count; Sperm Motility; Spermatozoa; Testosterone | 1999 |
Reproliferation and relocation of mouse male germ cells (gonocytes) during prespermatogenesis.
Topics: Aging; Animals; Animals, Newborn; Basement Membrane; Bromodeoxyuridine; Embryonic and Fetal Development; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Sertoli Cells; Spermatogenesis; Spermatozoa; Testis | 2000 |
Early hyperplastic renal growth after uninephrectomy in adult female rats.
Topics: Aging; Animals; Bromodeoxyuridine; DNA; Female; Growth Hormone; Hyperplasia; Immunohistochemistry; Kidney; Male; Mitosis; Nephrectomy; Organ Size; Radioimmunoassay; Rats; Receptor, IGF Type 1; Ribonucleases; RNA, Messenger | 2000 |
Cell cycle kinetics in corneal endothelium from old and young donors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bromodeoxyuridine; Cell Cycle; Cell Division; Cells, Cultured; Child; Child, Preschool; Endothelium, Corneal; Fibroblast Growth Factors; Fluorescent Antibody Technique, Indirect; Humans; Infant; Ki-67 Antigen; Kinetics; Microscopy, Confocal; Middle Aged | 2000 |
Induction of neurogenesis in the neocortex of adult mice.
Topics: Aging; Animals; Antigens, Differentiation; Apoptosis; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Mice; Neocortex; Nerve Degeneration; Nerve Regeneration; Neurons; Transcription Factors | 2000 |
Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Movement; Central Nervous System; Cerebellum; Dentate Gyrus; Embryonic and Fetal Development; Green Fluorescent Proteins; Indicators and Reagents; Intermediate Filament Proteins; Interneurons; Luminescent Proteins; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecules; Neural Pathways; Neurons; Olfactory Bulb; Promoter Regions, Genetic; Rats; Sialic Acids | 2000 |
Analysis of cerebrocortical neuronal migration in three-dimensional fetal mouse cerebral explants: comparison with in vivo.
Topics: Aging; Animals; Artificial Organs; Bromodeoxyuridine; Cell Movement; Cells, Cultured; Cerebral Cortex; Collagen; Culture Techniques; Mice; Neurons | 2000 |
Granule cell proliferation and axon terminal degradation in the dentate gyrus of gerbils (Meriones unguiculatus) during maturation, adulthood and aging.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Gerbillinae; Lysosomes; Male; Neuronal Plasticity; Presynaptic Terminals; Silver Staining | 2000 |
Vascular niche for adult hippocampal neurogenesis.
Topics: Aging; Animals; Animals, Newborn; Blood Vessels; Bromodeoxyuridine; Capillaries; Cell Aggregation; Cell Division; Cell Survival; Endothelium, Vascular; Female; Hippocampus; Intermediate Filament Proteins; Neovascularization, Physiologic; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Rats; Rats, Inbred F344; S Phase; Stem Cells | 2000 |
Do subplate neurons comprise a transient population of cells in developing neocortex of rats?
Topics: Acetylcholinesterase; Aging; Animals; Animals, Newborn; Atrophy; Biomarkers; Bromodeoxyuridine; Cell Survival; gamma-Aminobutyric Acid; Neocortex; Neurons; Neuropeptide Y; Rats; Somatostatin; Time Factors | 2000 |
Altered hormonal responsiveness of proliferation and apoptosis during myometrial maturation and the development of uterine leiomyomas in the rat.
Topics: Aging; Animals; Apoptosis; Bromodeoxyuridine; Cell Division; Estradiol; Estrus; Female; Gonadal Steroid Hormones; Homeostasis; Immunohistochemistry; In Situ Nick-End Labeling; Kinetics; Leiomyoma; Muscle Development; Myometrium; Ovary; Progesterone; Radioimmunoassay; Rats; Uterine Neoplasms | 2000 |
Proliferation and differentiation of thyrotrophs in the pars distalis of the rat pituitary gland during the fetal and postnatal period.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Division; Gestational Age; Pituitary Gland, Anterior; Rats; Rats, Wistar; Thyrotropin | 2001 |
Expression of NeuroD and TrkB in developing and aged mouse olfactory epithelium.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Embryo, Mammalian; Embryonic and Fetal Development; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Olfactory Mucosa; Receptor, trkB | 2001 |
Cell proliferation in the loop of henle in the developing rat kidney.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Division; Cell Nucleus; Loop of Henle; Rats; Rats, Sprague-Dawley | 2001 |
Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Hypertrophy; Insulin-Like Growth Factor I; Mice; Mice, Transgenic; Muscle, Skeletal; Phosphorylation; Reference Values; Retinoblastoma Protein; Time Factors; Tumor Suppressor Proteins | 2001 |
Neurogenesis by progenitor cells in the ischemic adult rat hippocampus.
Topics: Aging; Animals; Astrocytes; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyrus; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hippocampus; Ischemic Attack, Transient; Male; Mitosis; Nerve Tissue Proteins; Neurons; Prosencephalon; Rats; Rats, Wistar; RNA-Binding Proteins; Stem Cells | 2001 |
Modulation of the expression of the Cip/Kip family of cyclin-dependent kinase inhibitors in foetal developing lungs of hamsters.
Topics: Aging; Animals; Blotting, Western; Bromodeoxyuridine; Cell Cycle Proteins; Cell Division; Cricetinae; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Immunohistochemistry; Ki-67 Antigen; Lung; Male; Mesocricetus; Nuclear Proteins; Tumor Suppressor Proteins | 2001 |
Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations.
Topics: Aging; Alzheimer Disease; Animals; Antimetabolites; Behavior, Animal; Brain; Brain Chemistry; Bromodeoxyuridine; Cell Division; Cognition; Humans; Pregnenolone; Rats; Receptors, GABA-A; Sleep | 2001 |
Novel and transient populations of corticotropin-releasing hormone-expressing neurons in developing hippocampus suggest unique functional roles: a quantitative spatiotemporal analysis.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Corticotropin-Releasing Hormone; Dentate Gyrus; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; In Situ Hybridization; Isoenzymes; Neurons; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
Role of p14(ARF) in replicative and induced senescence of human fibroblasts.
Topics: Aging; Blotting, Northern; Bromodeoxyuridine; Cell Line; Cells, Cultured; Cellular Senescence; Fibroblasts; Genes, p53; Humans; Immunoblotting; Immunohistochemistry; Models, Biological; Proteins; Proto-Oncogene Proteins p21(ras); Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; Time Factors; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53; Up-Regulation | 2001 |
In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland.
Topics: Aging; Animals; Benzhydryl Compounds; Bromodeoxyuridine; DNA; Epithelium; Female; Mammary Glands, Animal; Mice; Phenols; Pregnancy; Prenatal Exposure Delayed Effects | 2001 |
Opioid system diversity in developing neurons, astroglia, and oligodendroglia in the subventricular zone and striatum: impact on gliogenesis in vivo.
Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antigens, Differentiation; Antigens, Surface; Astrocytes; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Differentiation; Cell Division; Glial Fibrillary Acidic Protein; Immunohistochemistry; Lateral Ventricles; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Neostriatum; Nerve Growth Factors; Neurons; Oligodendroglia; Opioid Peptides; Receptors, Opioid; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2001 |
[Mathematical and simulating model of accelerated aging induced by 5-bromo-2-deoxyuridine].
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Death; Humans; Mathematics; Models, Biological; Neoplasms; Point Mutation; Stochastic Processes | 2001 |
GABAergic neurons that pioneer hippocampal area CA1 of the mouse: morphologic features and multiple fates.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Bromodeoxyuridine; Cell Compartmentation; Cell Differentiation; Cell Division; Cell Lineage; Cell Movement; Cell Size; Dendrites; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Interneurons; Isoenzymes; Mice; Neurons; Parvalbumins; RNA, Messenger; Stem Cells | 2001 |
Development of laminar organization in the mushroom bodies of the cockroach: Kenyon cell proliferation, outgrowth, and maturation.
Topics: Aging; Animals; Body Patterning; Brain; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Differentiation; Cell Division; Cell Size; Growth Cones; Immunohistochemistry; Membrane Glycoproteins; Nerve Tissue Proteins; Nymph; Periplaneta; Silver Staining; Stem Cells; Synaptotagmins; Taurine | 2001 |
Neurogenesis in the subventricular zone and rostral migratory stream of the neonatal and adult primate forebrain.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Division; Cell Movement; Immunohistochemistry; Lateral Ventricles; Macaca mulatta; Neurons; Olfactory Bulb; Phenotype; Prosencephalon; Rats; Rodentia; Stem Cells | 2001 |
Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis.
Topics: Aging; Animals; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cognition; Dentate Gyrus; Injections, Intraventricular; Insulin-Like Growth Factor I; Male; Rats; Rats, Inbred BN; Rats, Inbred F344 | 2001 |
Ectopic expression of the neural cell adhesion molecule L1 in astrocytes leads to changes in the development of the corticospinal tract.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Carbocyanines; Cell Differentiation; Cerebral Cortex; Fetus; Fluorescent Dyes; Gene Expression Regulation, Developmental; Genotype; Glial Fibrillary Acidic Protein; Growth Cones; Immunohistochemistry; Leukocyte L1 Antigen Complex; Membrane Glycoproteins; Mice; Mice, Transgenic; Neural Cell Adhesion Molecules; Pons; Promoter Regions, Genetic; Pyramidal Tracts; Somatosensory Cortex; Ventral Thalamic Nuclei | 2001 |
Temporal and spatial differences of PSA-NCAM expression between young-adult and aged rats in normal and ischemic brains.
Topics: Aging; Animals; Antimetabolites; Brain; Brain Chemistry; Brain Ischemia; Bromodeoxyuridine; Cell Movement; Cerebrovascular Circulation; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neural Cell Adhesion Molecule L1; Neural Cell Adhesion Molecules; Rats; Rats, Wistar; Sialic Acids; Stem Cells | 2001 |
Fetal hippocampal CA3 cell grafts transplanted to lesioned CA3 region of the adult hippocampus exhibit long-term survival in a rat model of temporal lobe epilepsy.
Topics: Aging; Animals; Biomarkers; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Epilepsy, Temporal Lobe; Fetal Tissue Transplantation; Graft Survival; Hippocampus; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Pyramidal Cells; Rats; Rats, Inbred F344 | 2001 |
Expression and regulation of golli products of myelin basic protein gene during in vitro development of oligodendrocytes.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Compartmentation; Cell Differentiation; Cell Division; Cell Membrane; Cells, Cultured; Central Nervous System; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Immunohistochemistry; Mice; Mice, Inbred BALB C; Microglia; Mitogens; Myelin Basic Protein; Nerve Tissue Proteins; Neurotrophin 3; Oligodendroglia; Protein Isoforms; RNA, Messenger; Stem Cells; Transcription Factors; Tretinoin | 2001 |
Chemokine GRO1 and the spatial and temporal regulation of oligodendrocyte precursor proliferation.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Cerebral Cortex; Chemokines, CXC; Gene Expression Regulation, Developmental; Immunohistochemistry; Mice; Neurons; Oligodendroglia; Platelet-Derived Growth Factor; Spinal Cord; Stem Cells | 2001 |
Astrocytic and microglia cells reactivity induced by neonatal administration of glutamate in cerebral cortex of the adult rats.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Division; Cerebral Cortex; Disease Models, Animal; Female; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Lectins; Male; Microglia; Neurodegenerative Diseases; Neurotoxins; Rats; Rats, Wistar; Stem Cells; Synaptic Transmission; Vimentin | 2002 |
Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Bromodeoxyuridine; Cell Count; Cell Death; Cell Division; Female; Humans; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuroglia; Neurons; Phenotype | 2002 |
Differential responses of olfactory neurons to axotomy at embryonic and postnatal stages.
Topics: Aging; Animals; Apoptosis; Axotomy; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Survival; Chick Embryo; Chickens; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Neuronal Plasticity; Olfactory Receptor Neurons | 2002 |
Persistent engrailed expression is required to determine sensory axon trajectory, branching, and target choice.
Topics: Aging; Animals; Axons; Bromodeoxyuridine; Cell Lineage; Central Nervous System; Fluorescent Dyes; Homeodomain Proteins; Membrane Potentials; Neurons, Afferent; Periplaneta; Physical Stimulation; RNA, Antisense; Synapses; Time Factors; Transcription Factors | 2002 |
Hippocampal granule neuron production and population size are regulated by levels of bFGF.
Topics: Aging; Algorithms; Animals; Animals, Newborn; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Size; Cytoplasmic Granules; Dentate Gyrus; DNA; Fibroblast Growth Factor 2; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Knockout; Mutation; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Thymidine | 2002 |
The effects of social environment on adult neurogenesis in the female prairie vole.
Topics: Aging; Amygdala; Animals; Apoptosis; Arvicolinae; Bromodeoxyuridine; Cell Division; Female; In Situ Nick-End Labeling; Male; Neurons; Phenotype; Social Environment; Social Isolation; Staining and Labeling | 2002 |
Astroglia induce neurogenesis from adult neural stem cells.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Lineage; Cell Survival; Cells, Cultured; Coculture Techniques; Culture Media, Serum-Free; Fibroblasts; Hippocampus; Laminin; Neurons; Oligodendroglia; Organ Specificity; Rats; Rats, Inbred F344; Spinal Cord; Stem Cells | 2002 |
A model of accelerated aging induced by 5-bromodeoxyuridine.
Topics: Aging; Animals; Bromodeoxyuridine; Computer Simulation; Models, Biological; Rats; Stochastic Processes | 2002 |
Caenorhabditis briggsae: aging and the structural turnover of the outer cuticle surface and the intestine.
Topics: Aging; Animals; Bromodeoxyuridine; Ferritins; Glucuronates; Glycosaminoglycans; Hyaluronic Acid; Ions; Membranes; Nematoda; Neuraminic Acids; Ruthenium Red | 1978 |
Cell replication and aging: in vitro and in vivo studies.
Topics: Adult; Aged; Aging; Animals; Bone Marrow Cells; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Chromatids; Culture Media; DNA Replication; Humans; Rats; Skin; Time Factors | 1979 |
Sister chromatid exchanges and aging. III. The effect of donor age on mutagen-induced sister chromatid exchange in human diploid fibroblasts.
Topics: Acetoxyacetylaminofluorene; Adult; Aged; Aging; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Crossing Over, Genetic; Humans; Mitomycins; Mutagens; Skin | 1979 |
Removal of 5-bromo-2-deoxyuridine incorporated in liver DNA of newborn and young adult rats.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Carbon Radioisotopes; DNA; DNA Repair; Liver; Rats; Thymidine; Time Factors; Tritium | 1978 |
[Spontaneously occuring and experimentally induced enzymatic changes in the rat parotid gland: a possible experimental model of ageing (author's transl)].
Topics: Aging; Animals; Bromodeoxyuridine; Chemical Phenomena; Chemistry; DNA; Genetic Code; Isoamylase; Models, Biological; Parotid Gland; Protein Biosynthesis; Rats | 1977 |
Endothelial modulation of DNA synthesis in isolated arteries of the rat.
Topics: Aging; Animals; Bromodeoxyuridine; Carotid Arteries; Dinoprostone; DNA; Endothelium, Vascular; Iloprost; Indomethacin; Male; Methylene Blue; Organ Culture Techniques; Rats; Rats, Inbred WKY; Renal Artery; Transforming Growth Factor beta; Tunica Media | 1992 |
Bromodeoxyuridine immunohistochemistry for evaluating age-related changes in the rat mandibular condyle decalcified by intravenous infusion.
Topics: Aging; Animals; Bromodeoxyuridine; Calcium; Cell Division; Edetic Acid; Immunoenzyme Techniques; Infusions, Intravenous; Male; Mandibular Condyle; Rats; Rats, Sprague-Dawley | 1992 |
[Carcinogenesis induced by the neonatal administration of 5-bromo-2'-deoxyuridine and subsequent exposure to N-nitrosomethylurea in rats].
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Drug Interactions; Female; Life Tables; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Sex Factors | 1992 |
[Carcinogenesis induced by the neonatal administration of 5-bromo-2'-deoxyuridine and subsequent exposure to estradiol benzoate in female BALB/c mice].
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Drug Interactions; Estradiol; Female; Incidence; Life Tables; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Time Factors | 1992 |
Age-related changes of the antigen-specific antibody formation in vitro and PHA-induced T-cell proliferation in individuals who met the health criteria of the Senieur protocol.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antibody Formation; Antibody Specificity; Bromodeoxyuridine; Cell Division; Clinical Protocols; Hemocyanins; Humans; Immunophenotyping; Interleukin-2; Phytohemagglutinins; Receptors, Interleukin-2; T-Lymphocytes | 1992 |
Effect of neonatal exposure to 5-bromo-2'-deoxyuridine on life span, estrus function and tumor development in rats--an argument in favor of the mutation theory of aging?
Topics: Aging; Animals; Animals, Newborn; Body Weight; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Estrus; Female; Longevity; Male; Mutation; Neoplasms, Experimental; Organ Size; Ovariectomy; Pituitary Gland, Anterior; Rats | 1992 |
Formation and preservation of cortical layers in slice cultures.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; Cell Movement; Cerebral Cortex; Culture Techniques; Embryo, Mammalian; Gestational Age; Neurons; Rats; Tissue Preservation | 1992 |
Mechanisms of nascent fiber formation during avian skeletal muscle hypertrophy.
Topics: Aging; Animals; Bromodeoxyuridine; Chickens; Hypertrophy; Immunohistochemistry; Models, Anatomic; Muscle Development; Muscles; Myosins; Wings, Animal | 1992 |
Renewed DNA synthesis in senescent WI-38 cells by expression of an inducible chimeric c-fos construct.
Topics: Aging; Blotting, Northern; Bromodeoxyuridine; Cell Death; Cell Division; Cells, Cultured; Chimera; DNA; Fibroblasts; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Metallothionein; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Thymidine; Transfection; Zinc | 1992 |
Role of prolactin versus growth hormone on islet B-cell proliferation in vitro: implications for pregnancy.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Division; Cells, Cultured; Female; Growth Hormone; Growth Substances; Immunohistochemistry; Islets of Langerhans; Kinetics; Microscopy, Fluorescence; Mitosis; Pregnancy; Prolactin; Rats; Rats, Inbred Strains | 1991 |
Evaluation of in vitro bromodeoxyuridine labeling of breast carcinomas with the use of a commercial kit.
Topics: Aging; Breast Neoplasms; Bromodeoxyuridine; Carcinoma; Evaluation Studies as Topic; Female; Humans; Lymph Nodes; Middle Aged; Reagent Kits, Diagnostic; Receptors, Estrogen; Receptors, Progesterone | 1991 |
Proliferation of normal breast epithelial cells as shown by in vivo labeling with bromodeoxyuridine.
Topics: Adult; Aged; Aging; Breast; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Cell Nucleus; Epithelial Cells; Female; Humans; Immunoenzyme Techniques; Menstrual Cycle; Middle Aged; Reference Values; Tissue Distribution | 1991 |
Cell proliferation in the subependymal layer of the postnatal marmoset, Callithrix jacchus.
Topics: Aging; Animals; Autoradiography; Brain; Bromodeoxyuridine; Callithrix; Cell Division; Immunohistochemistry | 1990 |
Rod photoreceptor development in vitro: intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina.
Topics: Aging; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Embryonic and Fetal Development; Eye Proteins; Female; Fluorescent Antibody Technique; Photoreceptor Cells; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; Rod Opsins | 1990 |
Cell proliferation within the growth plate of long bones assessed by bromodeoxyuridine uptake and its relationship to glucose 6-phosphate dehydrogenase activity.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Division; DNA; Fluorescent Antibody Technique; Glucosephosphate Dehydrogenase; Growth Plate; Humans; Male; Metatarsus; Rats; Tibia | 1990 |
Increased numbers of extra-adrenal chromaffin cells in the abdominal paraganglia of senescent F344 rats: a possible role for the glucocorticoid receptor.
Topics: Adrenal Medulla; Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Division; Ganglia, Sympathetic; Male; Rats; Rats, Inbred F344; Receptors, Glucocorticoid | 1990 |
Cycling patterns of hemopoietic stem cell subpopulations in young and old BDF1 mice.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Cycle; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred Strains | 1989 |
The phytohemagglutinin response of human peripheral blood lymphocytes as a function of donor age: a re-examination using BrdU-Hoechst flow cytometry.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bromodeoxyuridine; Child; Child, Preschool; Flow Cytometry; Humans; Infant; Infant, Newborn; Lymphocyte Activation; Middle Aged; Phytohemagglutinins | 1988 |
Baseline frequency of sister-chromatid exchanges (SCE) in newborn lymphocytes and its relationship to in vivo aging in humans.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Bromodeoxyuridine; Cells, Cultured; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Lymphocytes; Male; Middle Aged; Reference Values; Sex Factors; Sister Chromatid Exchange | 1985 |
BrdU-Hoechst flow cytometry reveals regulation of human lymphocyte growth by donor-age-related growth fraction and transition rate.
Topics: Aging; Blood Donors; Bromodeoxyuridine; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Lymphocyte Activation; Lymphocytes; Models, Biological; Phytohemagglutinins | 1985 |
Galactosyltransferase activities in pancreas, liver and gut of the developing rat.
Topics: Acetamides; Aging; Animals; Bromodeoxyuridine; Carbon Isotopes; Cell Fractionation; Cytoplasmic Granules; Electrophoresis, Paper; Embryonic and Fetal Development; Female; Galactosamine; Galactose; Glucosamine; Hexosyltransferases; Intestine, Small; Liver; Organ Culture Techniques; Pancreas; Rats; Subcellular Fractions | 1973 |
Differential incorporation of 5-bromodeoxyuridine into DNA puffs of larval salivary gland chromosomes in Rhynchosciara.
Topics: Aging; Animals; Autoradiography; Base Sequence; Bromodeoxyuridine; Centrifugation, Density Gradient; Chromosomes; DNA; Genes; Insecta; Larva; Microscopy, Phase-Contrast; Nucleotides; Salivary Glands; Tritium | 1970 |