bromodeoxyuridine has been researched along with Acute Confusional Senile Dementia in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.00) | 18.7374 |
| 1990's | 2 (4.00) | 18.2507 |
| 2000's | 23 (46.00) | 29.6817 |
| 2010's | 21 (42.00) | 24.3611 |
| 2020's | 3 (6.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, L; Ren, Y; Wu, Q; Zhang, Y | 1 |
| Gao, JY; Guo, JJ; Li, GY; Li, LP; Li, WY; Lin, SY; Liu, ZT; Ma, YT; Pan, ST; Shen, W; Wang, QW; Xiao, B; Xie, K | 1 |
| Aghajanov, M; Chavushyan, V; Danielyan, M; Davtyan, T; Margaryan, T; Matinyan, S; Yenkoyan, K | 1 |
| Alquézar, C; Bartolomé, F; Campillo, NE; Carro, E; Del Cerro, P; González-Naranjo, P; Martín-Requero, Á; Páez, JA; Pérez, C | 1 |
| Bolos, M; Carro, E; Ferrer, I; Ordoñez-Gutierrez, L; Spuch, C; Wandosell, F | 1 |
| Sisodia, SS; Veeraraghavalu, K | 1 |
| Domingo, JL; Heredia, L; Ribes, D; Torrente, M; Vicens, P | 1 |
| Kim, HN; Lee, PH; Oh, SH; Park, HJ; Shin, JY | 1 |
| Bao, X; Cai, Y; Chen, J; Fan, X; Huang, J; Huang, W; Sun, D; Xu, H; Zhao, J | 1 |
| Bauer, G; Brinton, RD; Irwin, RW; Loya, CM; Rodgers, KE; Rogawski, MA; Salituro, FG; Solinsky, CM | 1 |
| Adame, A; Brandstaetter, H; Desplats, P; Florio, J; Mante, M; Masliah, E; Meier, D; Rockenstein, E; Ubhi, K; Winter, S | 1 |
| Aubert, I; Maliszewska-Cyna, E; Xhima, K | 1 |
| Cao, W; Cui, Y; Guan, F; Li, D; Liu, M; Lv, P; Ma, S; Qu, R; Xing, Q; Yang, B; Yao, N; Zhang, C | 1 |
| Gu, HG; Hong, LP; Leng, SL; Long, DH; Xuan, AG; Yang, DD | 1 |
| Akaike, A; Kihara, T; Niidome, T; Sugimoto, H; Taniuchi, N | 1 |
| Bhaskar, K; Herrup, K; Lamb, BT; Patil, AR; Pimplikar, SW; Varvel, NH | 1 |
| Ji, WD; Long, DH; Luo, M; Xuan, AG | 1 |
| Kohsaka, S; Maekawa, M; Namba, T; Uchino, S; Yuasa, S | 1 |
| Choi, SH; Sisodia, SS; Veeraraghavalu, K | 1 |
| Teng, WP; Wang, CY; Wang, SL; Wang, T; Wang, ZY; Xie, JW; Zhao, BL; Zheng, W | 1 |
| Calkins, MJ; Reddy, PH | 1 |
| Begus-Nahrmann, Y; Biber, K; Heinrich, A; Hölter, SM; Langkopf, BH; Lie, DC; Liss, B; Rolyan, H; Rudolph, KL; Scheffold, A; Thal, DR; Vogt-Weisenhorn, DM; Wurst, W | 1 |
| Adame, A; Blanchard, J; Crews, L; Doppler, E; Grundke-Iqbal, I; Iqbal, K; Li, B; Mante, M; Masliah, E; Moessler, H; Novak, P; Rockenstein, E; Ubhi, K | 1 |
| Casamenti, F; Ed Dami, T; Fiorentini, A; Grossi, C; Luccarini, I; Traini, C | 1 |
| Anglés, N; Boada, M; Bolea, I; Comes, G; Escorihuela, RM; Fernández-Fernández, L; Hidalgo, J; Morelló, JR; Murtra, P; Ramirez, B; Reguant, J; Ruiz, J; Unzeta, M; Valente, T | 1 |
| Dahmen, M; Hol, EM; Kamphuis, W; Kooijman, L; Orre, M | 1 |
| Bigler, S; Brinton, RD; Farley, JM; Ou, X; Stockmeier, C; Sun, C; Wang, JM | 1 |
| Asalgoo, S; Esmaeilzade, B; Hejazian, LB; Hosseini, SM; Joghataei, MT; Moghani Ghoroghi, F; Najafzade, N; Nobakht, M; Rahbar Roshandel, N; Rasouli, H; Samadi Kuchaksaraei, A | 1 |
| Abbott, AC; Aranguiz, FC; Calderon Toledo, C; Inestrosa, NC; Varela-Nallar, L | 1 |
| Chen, Y; Coopersmith, R; Hines-Peralta, A; Ivins, KJ; Kozlowski, MR; Manly, SP; McPhie, DL; Neve, KA; Neve, RL | 1 |
| Austin, G; Chen, X; DeGasperi, R; Elder, GA; Gama Sosa, MA; Gluck, K; Haroutunian, V; Hof, PR; Robakis, NK; Wen, PH; Younkin, LH; Younkin, SG | 1 |
| Bredesen, DE; Galvan, V; Gorostiza, OF; Greenberg, DA; Jin, K; Mao, XO; Xie, L | 1 |
| Chen, J; Chen, LF; Gan, L; Kwon, H; Mucke, L; Mueller-Steiner, S; Yi, S; Zhou, Y | 1 |
| Boekhoorn, K; Joels, M; Lucassen, PJ | 1 |
| Adame, A; Crews, L; Mante, M; Masliah, E; Moessler, H; Rockenstein, E | 1 |
| De Gasperi, R; Elder, GA; Gama Sosa, MA | 1 |
| Becker, M; Lavie, V; Solomon, B | 1 |
| Shen, CK; Tsai, KJ; Tsai, YC | 1 |
| Götz, J; Hoerndli, FJ; Papassotiropoulos, A; Pelech, S | 1 |
| Chi, L; Gan, L; Lan, X; Lien, L; Liu, R; Luo, C; Qiao, S; Yan Liu, Q | 1 |
| Chen, Q; Choi, SH; Nakajima, A; Sisodia, SS; Tang, YP; Xiong, X | 1 |
| Bai, Y; Fan, X; Li, D; Tang, J; Xu, H; Yang, L | 1 |
| Taupin, P | 1 |
| Currais, A; Malik, B; Soriano, S | 1 |
| Albu, P; Ferris, SH; Fischman, HK; Rainer, JD; Reisberg, B | 1 |
| Brenner, JW; Gokden, M; Lorenz, RG; Roth, KA; Selznick, LA | 1 |
| Janicki, SM; Monteiro, MJ | 1 |
| Abrous, DN; Le Moal, M; Mayo, W | 1 |
| Bondolfi, L; Calhoun, M; Ermini, F; Jucker, M; Kuhn, HG; Staufenbiel, M; Walker, L; Wiederhold, KH | 1 |
| Elder, GA; Friedrich, VL; Robakis, NK; Shioi, J; Wen, PH | 1 |
1 review(s) available for bromodeoxyuridine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Research update: neurogenesis in adult brain and neuropsychiatric disorders.
Topics: Adult; Alzheimer Disease; Animals; Antidepressive Agents; Bromodeoxyuridine; Cell Differentiation; Hippocampus; Humans; Immunohistochemistry; Mental Disorders; Neurodegenerative Diseases; Neurons; Olfactory Bulb; Stem Cell Transplantation | 2006 |
49 other study(ies) available for bromodeoxyuridine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells.
Topics: alpha-Synuclein; Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Proliferation; Cognitive Dysfunction; Ki-67 Antigen; Mice; Mice, Transgenic; Neural Stem Cells; Neurogenesis | 2022 |
Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; Disease Models, Animal; Hippocampus; Mice; Neurogenesis; Swimming | 2022 |
Effects of β-amyloid (1-42) Administration on the Main Neurogenic Niches of the Adult Brain: Amyloid-Induced Neurodegeneration Influences Neurogenesis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidogenic Proteins; Animals; Brain; Bromodeoxyuridine; Hippocampus; Neurogenesis; Rats; Vascular Endothelial Growth Factor A | 2022 |
Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Bromodeoxyuridine; Case-Control Studies; Cell Line, Transformed; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Humans; Indazoles; Lymphocytes; Male; Middle Aged; Neuroprotective Agents; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Signal Transduction; Time Factors | 2018 |
Neurogenic effects of β-amyloid in the choroid plexus epithelial cells in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Bromodeoxyuridine; Cell Differentiation; Cells, Cultured; Choroid Plexus; Epithelial Cells; Humans; Immunoblotting; Immunohistochemistry; Mice; Mice, Transgenic; Neural Stem Cells; Neurogenesis; Polymerase Chain Reaction; Signal Transduction | 2013 |
Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Survival; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mutation; Neurons; Phenotype; Presenilin-1; Promoter Regions, Genetic; Prosencephalon; Stem Cells; Tamoxifen; Transgenes | 2013 |
Effects of an alpha7 nicotinic receptor agonist and stress on spatial memory in an animal model of Alzheimer's disease.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Benzamides; Bridged Bicyclo Compounds; Bromodeoxyuridine; Disease Models, Animal; Male; Maze Learning; Memory; Mice; Mice, Transgenic; Nicotinic Agonists; Space Perception; Stress, Psychological; Time Factors | 2013 |
Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; beta Catenin; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Hippocampus; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neurons; Phenotype; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2015 |
Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Bromodeoxyuridine; Cell Adhesion Molecules, Neuronal; Cell Line; Dentate Gyrus; Extracellular Matrix Proteins; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Memantine; Mice, Transgenic; Microglia; Nerve Tissue Proteins; Neuroglia; Neuroprotection; Plaque, Amyloid; Presenilin-1; Reelin Protein; Serine Endopeptidases; SOXB1 Transcription Factors | 2015 |
Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Bromodeoxyuridine; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Evaluation, Preclinical; Female; Humans; Male; Maximum Tolerated Dose; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; No-Observed-Adverse-Effect Level; Phosphorylation; Pregnanolone; Proliferating Cell Nuclear Antigen; Rabbits; Rats, Sprague-Dawley; Treatment Outcome | 2015 |
Neuro-peptide treatment with Cerebrolysin improves the survival of neural stem cell grafts in an APP transgenic model of Alzheimer disease.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Disease Models, Animal; Doublecortin Domain Proteins; Furin; Hippocampus; Humans; Immunohistochemistry; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasms; Nerve Growth Factors; Neural Stem Cells; Neurogenesis; Neuropeptides | 2015 |
A Comparative Study Evaluating the Impact of Physical Exercise on Disease Progression in a Mouse Model of Alzheimer's Disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Bromodeoxyuridine; Disease Models, Animal; Disease Progression; Exploratory Behavior; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Physical Conditioning, Animal; Spatial Memory; Time Factors | 2016 |
Human umbilical cord mesenchymal stem cells transplantation improves cognitive function in Alzheimer's disease mice by decreasing oxidative stress and promoting hippocampal neurogenesis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antigens, CD; Bromodeoxyuridine; Cognition Disorders; Disease Models, Animal; Hippocampus; Humans; Maze Learning; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Nitric Oxide; Phosphopyruvate Hydratase; Superoxide Dismutase | 2017 |
BDNF improves the effects of neural stem cells on the rat model of Alzheimer's disease with unilateral lesion of fimbria-fornix.
Topics: Alzheimer Disease; Animals; Animals, Newborn; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Differentiation; Disease Models, Animal; Fornix, Brain; Functional Laterality; Hippocampus; Male; Maze Learning; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Stem Cell Transplantation; Stem Cells | 2008 |
Differential regulation of neurogenesis in two neurogenic regions of APPswe/PS1dE9 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Exons; Gene Deletion; Hippocampus; Immunohistochemistry; Lateral Ventricles; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neurons; Neuropeptides; Presenilin-1; Proliferating Cell Nuclear Antigen | 2008 |
Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurons; Peptide Fragments | 2008 |
Effects of engrafted neural stem cells in Alzheimer's disease rats.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Differentiation; Disease Models, Animal; Embryo, Mammalian; Hippocampus; Indoles; Male; Memory; Multipotent Stem Cells; Nerve Tissue Proteins; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Growth Factor; Receptors, Nerve Growth Factor; Septum of Brain; Stem Cell Transplantation | 2009 |
The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus.
Topics: Aging; Alzheimer Disease; Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Proliferation; Excitatory Amino Acid Antagonists; Hippocampus; Intermediate Filament Proteins; Male; Memantine; Mice; Mice, Inbred C57BL; Nerve Regeneration; Nerve Tissue Proteins; Nestin; Neurogenesis; Neuroglia; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; SOXB1 Transcription Factors; Stem Cells; Up-Regulation | 2009 |
Expression of familial Alzheimer's disease-linked human presenilin 1 variants impair enrichment-induced adult hippocampal neurogenesis.
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Bromodeoxyuridine; Cell Proliferation; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Humans; Mice; Mutation; Neurogenesis; Presenilin-1; Rats | 2010 |
Huperzine A activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; beta Catenin; Blood-Retinal Barrier; Bromodeoxyuridine; Cell Survival; Cholinesterase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Microscopy, Electron, Scanning; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurogenesis; Olfactory Bulb; Presenilin-1; RNA, Messenger; Sesquiterpenes; Signal Transduction; Transfection; Wnt Proteins | 2011 |
Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; DNA, Mitochondrial; Hydrogen Peroxide; Mice; Mitochondria; Neurons; Rotenone | 2011 |
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Cycle; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Doublecortin Domain Proteins; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microglia; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Plaque, Amyloid; Presenilin-1; Synapses; Telomerase; Telomere | 2011 |
Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Bromodeoxyuridine; Cell Death; Ciliary Neurotrophic Factor; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurogenesis; Neuropeptides; Peptide Fragments; Peptides; Proliferating Cell Nuclear Antigen | 2011 |
Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: a study in APP mutant mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Proliferation; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Neuroglia; Neurons; Nitric Oxide Synthase Type II; Plaque, Amyloid | 2012 |
LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's disease.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Bromodeoxyuridine; Cell Proliferation; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Fatty Acids, Unsaturated; Humans; Learning; Male; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Muscle Strength; Mutation; Plaque, Amyloid; Polyphenols; Postural Balance; Reaction Time; Reflex; Sensory Gating | 2012 |
Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Calcium-Binding Proteins; CD3 Complex; Cell Differentiation; Cell Proliferation; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Gliosis; Humans; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Nerve Tissue Proteins; Neuroglia; Neurons; Oligodendrocyte Transcription Factor 2; Presenilin-1; Sequence Deletion; SOXB1 Transcription Factors | 2012 |
Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Anesthetics; Animals; Bromodeoxyuridine; Cell Count; Disease Models, Animal; Dopaminergic Neurons; Humans; Mice; Mice, Transgenic; Mutation; Pregnanolone; Presenilin-1; Substantia Nigra; tau Proteins; Tyrosine 3-Monooxygenase | 2012 |
Delivery of epidermal neural crest stem cells (EPI-NCSC) to hippocamp in Alzheimer's disease rat model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Bromodeoxyuridine; CA3 Region, Hippocampal; Cell Differentiation; Cholinergic Neurons; Disease Models, Animal; Glial Fibrillary Acidic Protein; Maze Learning; Neural Crest; Neural Stem Cells; Neuroglia; Peptide Fragments; Rats; Staining and Labeling | 2012 |
Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1ΔE9 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antipsychotic Agents; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Exons; Gene Expression Regulation; Hippocampus; Humans; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurogenesis; Neuropeptides; Phloroglucinol; Presenilin-1; Rats; Rats, Sprague-Dawley; SOXB1 Transcription Factors; Terpenes; Time Factors | 2013 |
DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; DNA; Genes, Dominant; Genetic Vectors; In Situ Nick-End Labeling; Mutation; Nervous System; Neurons; Organ Specificity; p21-Activated Kinases; Protein Serine-Threonine Kinases; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; Rats; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion; Signal Transduction | 2003 |
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Antigens, Differentiation; Bromodeoxyuridine; Cell Count; Cell Survival; Disease Models, Animal; Environment; Gene Expression; Hippocampus; Humans; Membrane Proteins; Mice; Mice, Transgenic; Mutation; Neurons; Peptide Fragments; Presenilin-1; Stem Cells | 2004 |
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bromodeoxyuridine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Platelet-Derived Growth Factor | 2004 |
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Bromodeoxyuridine; Cells, Cultured; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunohistochemistry; Lentivirus; Lysine; Microglia; Microscopy, Fluorescence; Models, Biological; Models, Genetic; Neurons; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2005 |
Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus.
Topics: Aged; Alzheimer Disease; Antimetabolites; Blood Vessels; Bromodeoxyuridine; Cell Proliferation; Cerebrovascular Circulation; Female; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Middle Aged; Nerve Fibers; Neuroglia; Neurons; Tissue Banks | 2006 |
Effects of Cerebrolysin on neurogenesis in an APP transgenic model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Death; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; In Situ Nick-End Labeling; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Neuropeptides; Neuroprotective Agents; Proliferating Cell Nuclear Antigen; Time Factors | 2007 |
Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Bromodeoxyuridine; Disease Models, Animal; Female; Immunization; Immunotherapy; Male; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Phenotype | 2007 |
G-CSF rescues the memory impairment of animal models of Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Bromodeoxyuridine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Immunohistochemistry; Injections, Subcutaneous; Maze Learning; Memory; Mice | 2007 |
Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antimetabolites; Apoptosis; Blotting, Western; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; DNA Replication; Gene Expression Regulation; Humans; Mitosis; Models, Neurological; Neuroblastoma; tau Proteins; Tissue Culture Techniques | 2007 |
Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice.
Topics: Adult Stem Cells; Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; beta-Galactosidase; Brain; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Glial Fibrillary Acidic Protein; Humans; Intermediate Filament Proteins; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nestin; Phosphopyruvate Hydratase; Plaque, Amyloid; Platelet-Derived Growth Factor | 2008 |
Adult neurogenesis is functionally associated with AD-like neurodegeneration.
Topics: Age Factors; Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Dentate Gyrus; Disease Models, Animal; Disease Progression; Mice; Mice, Knockout; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Presenilin-1; Presenilin-2 | 2008 |
Decreased hippocampal cell proliferation correlates with increased expression of BMP4 in the APPswe/PS1DeltaE9 mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Bromodeoxyuridine; Cell Count; Cell Division; Cerebral Cortex; Dentate Gyrus; Disease Models, Animal; Humans; Male; Mice; Mice, Transgenic; Oligonucleotides, Antisense; Presenilin-1; RNA, Messenger | 2008 |
Alzheimer's disease, aneuploidy and neurogenesis.
Topics: Alzheimer Disease; Aneuploidy; Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Proliferation; Hippocampus; Humans; Immunohistochemistry; Nervous System; Neurons | 2008 |
Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Apoptosis; beta Catenin; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Disease Models, Animal; Embryo, Mammalian; Hippocampus; Humans; Mice; Mice, Transgenic; Mutation; Neurons; Peptide Fragments; Presenilin-1; Up-Regulation | 2008 |
Sister chromatid exchanges and cell cycle kinetics in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Bromodeoxyuridine; Cell Cycle; Chromosome Aberrations; Crossing Over, Genetic; Female; Humans; Karyotyping; Leukocytes; Middle Aged; Mitomycin; Mitomycins; Mitotic Index; Mutation; Sister Chromatid Exchange | 1984 |
Enzyme-based antigen localization and quantitation in cell and tissue samples (Midwestern assay).
Topics: Alzheimer Disease; Animals; Antibodies, Antinuclear; Brain Neoplasms; Bromodeoxyuridine; Cytoskeletal Proteins; DNA; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Humans; Ki-67 Antigen; Mice; Spinal Cord; Substance P; tau Proteins; Tumor Cells, Cultured | 1997 |
Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant.
Topics: Alzheimer Disease; Bromodeoxyuridine; Cell Cycle; Cell Separation; Flow Cytometry; G1 Phase; HeLa Cells; Humans; Membrane Proteins; Mitosis; Mutation; Presenilin-1; Presenilin-2 | 1999 |
Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations.
Topics: Aging; Alzheimer Disease; Animals; Antimetabolites; Behavior, Animal; Brain; Brain Chemistry; Bromodeoxyuridine; Cell Division; Cognition; Humans; Pregnenolone; Rats; Receptors, GABA-A; Sleep | 2001 |
Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Bromodeoxyuridine; Cell Count; Cell Death; Cell Division; Female; Humans; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuroglia; Neurons; Phenotype | 2002 |
Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hippocampus; Intermediate Filament Proteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nestin; Neurons; Presenilin-1; Stem Cells; Tubulin | 2002 |