bromochloroacetic-acid and Rupture--Spontaneous

A case of ileal adenomyoma with goblet and Paneth cells is reported. A 75-year-old man died of ruptured hepatocellular carcinoma. As an incidental finding at autopsy, a 9 x 7 x 6 mm(3)-sized nodule was found in the ileal wall. Histologically, the lesion occupied the submucosa and muscularis propria, and consisted of glandular structures of various sizes and interlacing smooth muscle bundles surrounding the glandular elements. Goblet cells and Paneth cells were interspersed in the glandular element. Immunohistochemically, the glandular element was positive for cytokeratin (CK) 7 and negative for CK 20. This is the first reported case of adenomyoma of the gastrointestinal tract that contained Paneth cells. The result of the immunohistochemical staining favored the heterotopic pancreas theory concerning its pathogenesis. The appearance of goblet and Paneth cells might be the result of metaplasia.

Topics: Adenomyoma; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Fatal Outcome; Goblet Cells; Humans; Ileal Neoplasms; Immunohistochemistry; Keratin-20; Keratin-7; Keratins; Liver Neoplasms; Male; Neoplasms, Second Primary; Paneth Cells; Rupture, Spontaneous

We report the case of an 8-year-old child, presenting a rhabdoid tumor of the liver with spontaneous rupture, revealed by an intra-abdominal bleeding with rapidly fatal course. This clinical and pathological report raises the problem of the differential diagnosis of primary malignant hepatic tumors of the child with no alpha-foetoprotein increase.

Topics: Cell Division; Child; Diagnosis, Differential; Humans; Immunohistochemistry; Keratins; Liver Neoplasms; Male; Rhabdoid Tumor; Rupture, Spontaneous

It has generally been accepted that pseudomyxoma peritonei/disseminated peritoneal adenomucinosis originates from appendiceal low-grade adenomatous mucinous tumors. A woman who underwent an appendectomy 42 years ago, presented with a unilateral ovarian tumor whose immunohistochemical phenotype and its association with a teratoma, strongly suggest that pseudomyxoma peritonei originated from a ruptured mucinous tumour arising from a mature cystic teratoma.

Topics: Adenoma; Aged; Appendectomy; Douglas' Pouch; Fallopian Tubes; Female; Humans; Hysterectomy; Immunohistochemistry; Keratin-20; Keratins; Omentum; Ovarian Neoplasms; Ovariectomy; Pseudomyxoma Peritonei; Rupture, Spontaneous; Splenectomy; Teratoma

Topics: Adult; Cerebral Ventricles; Cerebral Ventriculography; Cholesterol; Dermoid Cyst; Humans; Keratins; Magnetic Resonance Imaging; Male; Pituitary Neoplasms; Rupture, Spontaneous; Tomography, X-Ray Computed

Topics: Aged; Fistula; Hearing Loss, Sensorineural; Humans; Immunohistochemistry; Keratins; Labyrinth Diseases; Male; Ossicular Replacement; Otosclerosis; Oval Window, Ear; Rupture, Spontaneous; Saccule and Utricle