bromochloroacetic-acid and Osteopoikilosis

bromochloroacetic-acid has been researched along with Osteopoikilosis* in 1 studies

Reviews

1 review(s) available for bromochloroacetic-acid and Osteopoikilosis

Article	Year
Primary thymic carcinoid with Cushing's syndrome. Virchows Archiv. A, Pathological anatomy and histopathology, 1992, Volume: 420, Issue:2 In a 52-year-old Caucasian man osteopoikilosis had been misdiagnosed roentgenologically 2 years before his death. Gradually he developed Cushing's syndrome and ultimately superior vena caval obstruction. At autopsy a primary thymic carcinoid with extensive osteoblastic bone metastasis was found. Immunohistochemically the tumor was shown to be positive for adrenocorticotropic hormone (ACTH), cytokeratin (KL1), neuron-specific enolase, synaptophysin, chromogranin and glucagon. Remarkably the tumour was negative for serotonin despite high urinary hydroxyindolacetic acid levels. Bilateral hyperplasia of the adrenal cortex was found. The adenohypophysis showed a considerable reduction of ACTH-producing cells and numerous Crooke's cells with a characteristic immunohistochemical pattern. Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Bone Neoplasms; Carcinoid Tumor; Cushing Syndrome; Diagnostic Errors; Humans; Keratins; Male; Middle Aged; Osteopoikilosis; Phosphopyruvate Hydratase; Radiography; Thymus Neoplasms; Vena Cava, Superior	1992

Article

Year

Primary thymic carcinoid with Cushing's syndrome.

Virchows Archiv. A, Pathological anatomy and histopathology, 1992, Volume: 420, Issue:2

In a 52-year-old Caucasian man osteopoikilosis had been misdiagnosed roentgenologically 2 years before his death. Gradually he developed Cushing's syndrome and ultimately superior vena caval obstruction. At autopsy a primary thymic carcinoid with extensive osteoblastic bone metastasis was found. Immunohistochemically the tumor was shown to be positive for adrenocorticotropic hormone (ACTH), cytokeratin (KL1), neuron-specific enolase, synaptophysin, chromogranin and glucagon. Remarkably the tumour was negative for serotonin despite high urinary hydroxyindolacetic acid levels. Bilateral hyperplasia of the adrenal cortex was found. The adenohypophysis showed a considerable reduction of ACTH-producing cells and numerous Crooke's cells with a characteristic immunohistochemical pattern.

Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Bone Neoplasms; Carcinoid Tumor; Cushing Syndrome; Diagnostic Errors; Humans; Keratins; Male; Middle Aged; Osteopoikilosis; Phosphopyruvate Hydratase; Radiography; Thymus Neoplasms; Vena Cava, Superior

1992