bromochloroacetic-acid and Lichen-Nitidus

Trichodysplasia spinulosa (TS) is a rare cutaneous condition associated with the TSPyV and characterized by skin-colored, folliculocentric papules with keratin spicule formation. TS is seen almost exclusively in immunosuppressed individuals, often presenting in patients with a history of solid organ transplantation or chemotherapy for a lymphoreticular malignancy. We report a case of widespread TS in a 9-year-old girl with a history of renal transplantation complicated by BK viremia, which is also caused by a polyomavirus, BKPyV. The clinical presentation of TS in this case morphologically resembled the more common, harmless skin condition known as "lichen nitidus," and was more extensive than expected for TS, creating a diagnostic challenge. This case illustrates an important presentation of severe TS of which transplant teams, oncologists, primary care providers, and dermatologists should be aware.

Topics: BK Virus; Child; Congenital Abnormalities; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Keratins; Kidney; Kidney Diseases; Kidney Transplantation; Lichen Nitidus; Polyomavirus; Polyomavirus Infections; Postoperative Complications; Skin; Skin Diseases; Tumor Virus Infections