bromochloroacetic-acid and Gingival-Hyperplasia

To immunohistochemically evaluate the cytokeratin (CK) pattern of expression in localized juvenile spongiotic gingival hyperplasia (LJSGH) as compared with the gingival epithelium (GE).. Ten cases of LJSGH were semiquantitatively evaluated for the immunohistochemical pattern of CK1/10, CK4, CK8/18, and CK19. GE controls were taken from 10 cases of reactive gingival fibroepithelial hyperplasia. GEs showed mean positivity rates of 80% for both CK1/10 and CK4, and 5% for both CK8/18 and CK19. LJSGHs showed mean positivity rates of 65% for CK19, 60% for CK8/18, 30% for CK4, and 5% for CK1/10. The differences between LJSGHs and GEs were statistically significant (P < 0.01).. The LJSGH pattern of CK expression is reminiscent of the profile described in the literature for the junctional epithelium (JE). Possibly, JE exteriorized from the gingival sulcus would be more prone to irritation from a variety of sources, resulting in inflammation and hyperplasia, with the subsequent development of LJSGH.

Topics: Adolescent; Child; Epithelial Attachment; Female; Gingiva; Gingival Hyperplasia; Humans; Immunohistochemistry; Keratins; Male

The aim of this study was to evaluate the marginal tissue response adjacent to implant supported overdentures. Twenty edentulous patients had 2 Astra Dental Implants placed in the canine region of the lower jaw. New overdentures were retained by individual ball attachments in 11 patients and by a bar attachment in 9 patients. Periodontal registrations were recorded 0 months, 6 months, 12 months and 24 months after the overdentures were inserted. One of the 40 fixtures was lost at the stage of abutment connection. No fixtures were lost during the 2- to 4-year observation period and no fixtures showed any periodontal signs of failure. At the 2-year examination, no pocket depths adjacent to the implants exceeded 4 mm and no bone loss exceeded 3 mm. The mean annual bone loss was less than 0.2 mm during the first 2 years. The preliminary results from this limited study were promising and showed that two osseointegrated Astra Dental Implants could successfully retain an overdenture in the lower jaw. However, long-term observation is needed for a definitive evaluation of this treatment concept.

Topics: Aged; Alveolar Bone Loss; Dental Implants; Dental Plaque Index; Denture, Overlay; Female; Gingival Hyperplasia; Humans; Keratins; Male; Mandible; Middle Aged; Periodontal Index

Topics: Cysts; Epithelium; Gingiva; Gingival Hyperplasia; Humans; Hydantoins; Keratins

Topics: Cell Membrane; Gingiva; Gingival Hyperplasia; Humans; Keratins; Microscopy, Electron

Topics: Adult; Female; Gingival Hyperplasia; Glycogen; Humans; Keratins; Keratosis; Leukoplakia; Male; Middle Aged