bromochloroacetic-acid and Fat-Necrosis

Pancreas acinar cell carcinoma (ACC) accounts for only 1-2% of pancreatic exocrine malignant tumor. The symptoms of patients with ACC are usually non-specific, for example the anorexia and weight loss. Patients may develop Schmid's triad including subcutaneous fat necrosis, polyarthritis, and eosinophilia. We reported a case of ACC which was manifested by subcutaneous nodule as initial clinical symptom. To our knowledge, this is the first reported case of ACC presenting as subcutaneous fat necrosis in Korea.

Topics: Carcinoma, Acinar Cell; Fat Necrosis; Humans; Keratins; Male; Middle Aged; Pancreatic Neoplasms; Subcutaneous Fat; Synaptophysin; Tomography, X-Ray Computed; Ultrasonography

Ninety-three male breast specimens have been examined for the presence of pseudoangiomatous hyperplasia of the mammary stroma which has hitherto been described almost exclusively in females. Forty-four cases (47.4%) showed some degree of hyperplasia, varying from small microscopic foci to extensive change involving 90% of the mammary tissue. All but one were found in association with gynaecomastia, early and intermediate stage. The association between pseudoangiomatous hyperplasia and benign proliferative lesions mirrors that reported in the female breast, and our findings suggest that the change may represent a stage in the maturation of newly formed mammary stroma.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Breast; Cell Adhesion Molecules; Fat Necrosis; Gynecomastia; Humans; Hyperplasia; Keratins; Male; Membrane Glycoproteins; Middle Aged; Mucin-1; Mucins; Platelet Endothelial Cell Adhesion Molecule-1; Vimentin; von Willebrand Factor