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bromobenzene and Acute Liver Injury, Drug-Induced

bromobenzene has been researched along with Acute Liver Injury, Drug-Induced in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (40.00)	18.7374
1990's	14 (23.33)	18.2507
2000's	11 (18.33)	29.6817
2010's	9 (15.00)	24.3611
2020's	2 (3.33)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Estes, SK; O'Brien, TP; Oyama, T; Pannala, VR; Printz, RL; Rahim, M; Reifman, J; Shiota, C; Shiota, M; Trenary, I; Wallqvist, A; Young, JD	1
Estes, SK; O'Brien, TP; Pannala, VR; Printz, RL; Rahim, M; Reifman, J; Shiota, C; Shiota, M; Trenary, I; Wallqvist, A; Young, JD	1
Fukuishi, N; Hwang, GW; Miura, N; Nonogaki, T; Ohtani, K; Shinohara, Y; Yoshioka, H	1
Cao, W; Cheng, N; He, L; Liu, Q; Ma, T; Peng, G; Zhao, H	1
Ali, SA; El-Rigal, NS; Hamed, MA	1
Sabina, EP; Vedi, M	1
El-Sharaky, AS; Eweda, SM; Kamel, MA; Newairy, AA	1
Gao, W; Minowa, Y; Mizukawa, Y; Nakatsu, N; Ohno, Y; Urushidani, T; Yamada, H	1
Gesztelyi, R; Jalali, A; Jalali, M; Juhasz, B; Kalantari, H; Mahdavinia, M; Salimi, A; Tosaki, A	1
Li, S; Peng, R; Wang, H; Wu, D	1
Apte, UM; Bucci, TJ; Manautou, JE; Mehendale, HM; Ronis, MJ; Shankar, K; Vaidya, VS	1
Akamatsu, S; Kagaya, N; Kamiyoshi, A; Kawase, M; Muto, S; Tagawa, Y; Yagi, K	1
Groten, JP; Heijne, WH; Klaassen, CD; Slitt, AL; Stierum, RH; van Bladeren, PJ; van Ommen, B	1
Groten, JP; Heijne, WH; Lamers, RJ; van Bladeren, PJ; van Nesselrooij, JH; van Ommen, B	1
Sano, N; Sasamoto, T; Takikawa, H	1
Farrant, RD; Holmes, E; Nicholson, JK; Waterfield, CJ; Waters, NJ	1
Horbach, GJ; Kloks, CP; Mellema, JR; Ploemen, JP; Schoonen, WG; Smit, MJ; Tas, AC; van Nesselrooij, JH; Vogels, JT; Zandberg, P; Zuylen, CT	1
Kiyosawa, N; Manabe, S; Tanaka, K; Watanabe, K	1
Dent, JG; Leonard, TB	1
Kuroiwa, Y; Misawa, S; Nakamura, T; Tanaka, E; Yoshida, T	1
Berman, ML; Harbison, RD; James, RC; Smith, AC	1
Rikans, LE	1
Hughes, H; Mitchell, JR; Smith, CV	1
Alcaraz, MJ; Bustos, G; Ferrándiz, ML; Gunasegaran, R; Payá, M	1
Lertratanangkoon, K; Scimeca, JM	1
Casini, AF; Comporti, M; Del Bello, B; Goldring, C; Maellaro, E	1
Alcaraz, MJ; Ferrandiz, ML; Payá, M; Sanz, MJ	1
Grewal, KK; Racz, WJ; Rafeiro, E	1
Gandolfi, AJ; Lind, RC	2
Roberts, SM; Salminen, WF; Voellmy, R	1
Delnomdedieu, M; Hedlund, LW; Johnson, GA; Maronpot, RR	1
Hennig, GE; Manautou, JE; Silva, VM; Whiteley, HE	1
Miyamoto, Y; Mizutani, T	1
Piotrowski, JK; Szymańska, JA	1
Carlson, GP; Day, BJ; DeNicola, DB; Marcus, CB	1
Brauer, M; Locke, S	1
Brandt, I; Brittebo, EB; Eriksson, C	1
Bursch, W; Schulte-Hermann, R	1
Dixon, PA; Udeagha, AU	1
Gandy, J; Harbison, RD; Hinson, JA; James, RC; Kerger, BD; Roberts, SM	1
Bucci, TJ; Gandy, J; Harbison, RD; James, RC; Kerger, BD; Roberts, SM	1
Lau, SS; Monks, TJ	1
Aiso, S; Buehler, R; Ishii, H; Ito, D; Kato, S; Takagi, T; Takekawa, S; Tsuchiya, M; von Wartburg, JP	1
Brendel, K; Fisher, RL; Gandolfi, AJ; Sipes, IG; Smith, PF; Stine, ER	1
Farber, JL	1
Coulombe, PA; Gascon-Barré, M; Haddad, P	1
Brodeur, J; Goyal, R	1
Horning, EC; Horning, MG; Lertratanangkoon, K	1
Esteller, A; González, J; Muñoz, ME	1
Comporti, M	1
Farag, MM; Volicer, L	1
Brodeur, J; Chakrabarti, S	1
Casini, AF; Comporti, M; Pompella, A	1
Esteller, A; González, J	1
McMillan, DA; Schnell, RC	1
Dumont, A; Gascon-Barré, M; Haddad, P	1

Reviews

3 review(s) available for bromobenzene and Acute Liver Injury, Drug-Induced

Article	Year
The contribution of bromobenzene to our current understanding of chemically-induced toxicities. Life sciences, 1988, Volume: 42, Issue:13 Topics: Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Glutathione; Kidney Diseases	1988
Xenobiotics, drug metabolism, and liver injury. Monographs in pathology, 1987, Issue:28 Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glutathione; Humans; Inactivation, Metabolic; Liver; Mixed Function Oxygenases; Oxidation-Reduction	1987
Lipid peroxidation and cellular damage in toxic liver injury. Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 53, Issue:6 Topics: Aldehydes; Animals; Antioxidants; Bromobenzenes; Bromotrichloromethane; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Endoplasmic Reticulum; Fatty Liver, Alcoholic; Free Radicals; Glucosephosphate Dehydrogenase; In Vitro Techniques; Lipid Peroxides; Liver; Malondialdehyde; Mice; Microsomes, Liver; Phenylhydrazines; Rats; Spectrophotometry, Atomic; Sulfhydryl Compounds; Tissue Distribution	1985

Other Studies

57 other study(ies) available for bromobenzene and Acute Liver Injury, Drug-Induced

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
Mechanism-based identification of plasma metabolites associated with liver toxicity. Toxicology, 2020, Volume: 441 Topics: Acetaminophen; Animals; Biomarkers; Bromobenzenes; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Liver; Male; Metabolomics; Rats, Sprague-Dawley	2020
Toxicant-Induced Metabolic Alterations in Lipid and Amino Acid Pathways Are Predictive of Acute Liver Toxicity in Rats. International journal of molecular sciences, 2020, Nov-04, Volume: 21, Issue:21 Topics: Acetaminophen; Acute Disease; Amino Acids; Animals; Biomarkers; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Hazardous Substances; Hepatocytes; Lipid Metabolism; Liver; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Prognosis; Rats; Rats, Sprague-Dawley; Transcriptome	2020
Chronotoxicity of bromobenzene-induced hepatic injury in mice. The Journal of toxicological sciences, 2017, Volume: 42, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Bromobenzenes; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Creatinine; Kidney; Liver; Male; Malondialdehyde; Mice, Inbred ICR; Solvents	2017
Hepatoprotective Effects of the Honey of Apis cerana Fabricius on Bromobenzene-Induced Liver Damage in Mice. Journal of food science, 2018, Volume: 83, Issue:2 Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bees; Bromobenzenes; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Honey; Humans; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Plant Extracts; Polyphenols; Protective Agents; Superoxide Dismutase	2018
Effects of black seed oil on resolution of hepato-renal toxicity induced bybromobenzene in rats. European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:5 Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Kidney; Kidney Diseases; Liver; Male; Nigella sativa; Plant Oils; Rats; Rats, Wistar; Seeds	2013
Assessment of hepatoprotective and nephroprotective potential of withaferin A on bromobenzene-induced injury in Swiss albino mice: possible involvement of mitochondrial dysfunction and inflammation. Cell biology and toxicology, 2016, Volume: 32, Issue:5 Topics: Animals; Antioxidants; Bromobenzenes; Chemical and Drug Induced Liver Injury; Female; Inflammation; Interleukin-1beta; Kidney; Kidney Diseases; Lipid Peroxidation; Liver; Male; Mice; Mitochondria; Oxidants; Oxidative Stress; Random Allocation; Tumor Necrosis Factor-alpha; Withanolides	2016
Protective effect of ginger extract against bromobenzene-induced hepatotoxicity in male rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7 Topics: Animals; Apoptosis; Bromobenzenes; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Electrophoresis, Agar Gel; Ethanol; Free Radicals; Liver; Liver Function Tests; Male; Mixed Function Oxygenases; Plant Extracts; Rats; Solvents; Zingiber officinale	2009
Mechanism-based biomarker gene sets for glutathione depletion-related hepatotoxicity in rats. Toxicology and applied pharmacology, 2010, Sep-15, Volume: 247, Issue:3 Topics: Animals; Bromobenzenes; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression; Gene Expression Profiling; Genetic Markers; Glutathione; Ketones; Liver; Liver Function Tests; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley	2010
Protective effect of Cassia fistula fruit extract against bromobenzene-induced liver injury in mice. Human & experimental toxicology, 2011, Volume: 30, Issue:8 Topics: Administration, Oral; Animals; Bromobenzenes; Cassia; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Liver; Liver Function Tests; Male; Mice; Plant Extracts; Protective Agents	2011
[Serum glutathione S-transferase in bromobenzene-induced acute hepato-toxicity in mice]. Wei sheng yan jiu = Journal of hygiene research, 2001, Volume: 30, Issue:3 Topics: Alanine Transaminase; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Glutathione Transferase; Male; Mice	2001
Type 1 diabetic mice are protected from acetaminophen hepatotoxicity. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bromobenzenes; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Colchicine; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA; Drug Therapy, Combination; Liver; Liver Regeneration; Male; Mice; Microsomes, Liver; Proliferating Cell Nuclear Antigen	2003
Liver protection by bis(maltolato)zinc(II) complex. Experimental animals, 2004, Volume: 53, Issue:1 Topics: Animals; Bromobenzenes; Cells, Cultured; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Disease Models, Animal; Liver Diseases; Mice; Mice, Inbred BALB C; Organometallic Compounds; Rats; Transaminases	2004
Bromobenzene-induced hepatotoxicity at the transcriptome level. Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:2 Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Gene Expression Regulation; Glutathione; Liver; Male; Microarray Analysis; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred Strains; Time Factors; Transcription, Genetic	2004
Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis. Toxicologic pathology, 2005, Volume: 33, Issue:4 Topics: Amino Acids; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gene Expression Profiling; Liver; Male; Necrosis; Principal Component Analysis; Rats; Rats, Wistar; Transcription, Genetic	2005
Biliary excretion of sulfated bile acids and organic anions in zone 1- and zone 3-injured rats. Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 1 Topics: Animals; Anions; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Biliary Tract; Biological Transport; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Male; Phenolphthaleins; Pravastatin; Propanols; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid	2006
Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis. Journal of proteome research, 2006, Volume: 5, Issue:6 Topics: Animals; Biomarkers; Blood Proteins; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Magnetic Resonance Spectroscopy; Male; Necrosis; Pyrrolidonecarboxylic Acid; Rats	2006
Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Kidney; Liver; Magnetic Resonance Spectroscopy; Necrosis; Principal Component Analysis; Rats	2007
Characterization of resistance to bromobenzene-induced hepatotoxicity by microarray. The Journal of toxicological sciences, 2007, Volume: 32, Issue:2 Topics: Animals; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bromobenzenes; Chemical and Drug Induced Liver Injury; Down-Regulation; Drug Resistance; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Injections, Intraperitoneal; Liver; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Transcription, Genetic; Up-Regulation	2007
Effects of H2 receptor antagonists on the hepatotoxicity of various chemicals. Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:3 Topics: 1-Propanol; Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cimetidine; Drug Antagonism; Drug Synergism; Histamine H2 Antagonists; Imidazoles; Liver; Male; Propanols; Pyrimidinones; Ranitidine; Rats; Rats, Inbred F344	1984
Effects of allyl alcohol and bromobenzene on trimethadione metabolism in the rat. Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:1 Topics: 1-Propanol; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dimethadione; Kinetics; Liver; Male; Microsomes, Liver; Oxazoles; Oxidation-Reduction; Propanols; Proteins; Rats; Rats, Inbred Strains; Trimethadione	1984
Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity. Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23 Topics: Alanine Transaminase; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Female; Halothane; Hyperthyroidism; Male; Mice; Necrosis; Rats; Sex Factors; Species Specificity; Starvation; Time Factors; Triiodothyronine	1983
Influence of aging on the susceptibility of rats to hepatotoxic injury. Toxicology and applied pharmacology, 1984, Volume: 73, Issue:2 Topics: 1-Propanol; Aging; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Endoplasmic Reticulum; Galactosamine; Liver; Male; NADH Dehydrogenase; Necrosis; Propanols; Rats; Rats, Inbred F344	1984
Free radicals in vivo. Covalent binding to lipids. Molecular pharmacology, 1984, Volume: 26, Issue:1 Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Free Radicals; Furans; Furosemide; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains	1984
Hispidulin protection against hepatotoxicity induced by bromobenzene in mice. Life sciences, 1994, Volume: 55, Issue:8 Topics: Acetylcysteine; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Flavones; Flavonoids; Glutathione; Lipid Peroxides; Liver Diseases; Male; Mice	1994
Prevention of bromobenzene toxicity by N-acetylmethionine: correlation between toxicity and the impairment in O- and S-methylation of bromothiocatechols. Toxicology and applied pharmacology, 1993, Volume: 122, Issue:2 Topics: Animals; Bromobenzenes; Catechols; Chemical and Drug Induced Liver Injury; Cricetinae; Kidney Diseases; Liver Diseases; Male; Mesocricetus; Methionine; Methylation; Necrosis; Species Specificity; Sulfhydryl Compounds	1993
Determination of 4-hydroxynonenal by high-performance liquid chromatography with electrochemical detection. Lipids, 1993, Volume: 28, Issue:2 Topics: Aldehydes; Animals; Bromobenzenes; Bromotrichloromethane; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cricetinae; Electrochemistry; Kidney; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Microsomes, Liver; Rats	1993
Effects of phenolic compounds on bromobenzene-mediated hepatotoxicity in mice. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Animals; Bromobenzenes; Cell Death; Chemical and Drug Induced Liver Injury; Flavonoids; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Phenols; Silymarin	1993
Bromobenzene and furosemide hepatotoxicity: alterations in glutathione, protein thiols, and calcium. Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:3 Topics: Animals; Bromobenzenes; Calcium; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytosol; Diuretics; Furosemide; Glutathione; Homeostasis; Male; Mice; Mice, Inbred Strains; Proteins; Sulfhydryl Compounds	1996
Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney. Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1 Topics: Administration, Inhalation; Administration, Oral; Alanine Transaminase; Allyl Compounds; Animals; Biomarkers; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chloroform; Dimethyl Sulfoxide; Drug Administration Schedule; Glutathione; Guinea Pigs; Halothane; Kidney; Kidney Tubular Necrosis, Acute; Liver; Male; Necrosis; Rats; Rats, Sprague-Dawley; Sulfides	1997
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction. Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2 Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cocaine; Fever; Heat-Shock Proteins; Hyperthermia, Induced; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred ICR	1997
Magnetic resonance microscopy and histopathology: comparative approach of bromobenzene-induced hepatotoxicity in the rat. Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2 Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Female; Histocytochemistry; Liver Diseases; Microscopy; Rats; Rats, Inbred F344; Reproducibility of Results; Sensitivity and Specificity	1998
Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice. Toxicology, 1998, May-15, Volume: 127, Issue:1-3 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Blood Urea Nitrogen; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Clofibrate; Injections, Intraperitoneal; Kidney; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL; Microbodies; Sulfhydryl Compounds	1998
Modulation of halobenzene-induced hepatotoxicity by DT-diaphorase modulators, butylated hydroxyanisole and dicoumarol: evidence for possible involvement of quinone metabolites in the toxicity of halobenzenes. Toxicology letters, 1999, Mar-08, Volume: 105, Issue:1 Topics: Alanine Transaminase; Animals; Benzene Derivatives; Bromobenzenes; Butylated Hydroxyanisole; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Dicumarol; Diet; Enzyme Induction; Enzyme Inhibitors; Inactivation, Metabolic; Liver; Male; Mice; NAD(P)H Dehydrogenase (Quinone)	1999
Hepatoprotection by dimethyl sulfoxide. II. Characterization of optimal dose and the latest time of administration for effective protection against chloroform and bromobenzene induced injury. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:6 Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chloroform; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Free Radical Scavengers; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Time Factors	1999
Hepatotoxicity of monobromobenzene and hexabromobenzene: effects of repeated dosage in rats. Chemosphere, 2000, Volume: 41, Issue:10 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Coproporphyrins; Female; Glutathione; Heme; Kinetics; Liver; Liver Diseases; Porphobilinogen Synthase; Rats; Uroporphyrins	2000
Effect of p-xylene inhalation on the bioactivation of bromobenzene in rat lung and liver. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 19, Issue:1 Topics: Administration, Inhalation; Animals; Biological Availability; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Lung; Lung Diseases; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Xylenes	1992
Proton magnetic resonance imaging and phosphorus-31 magnetic resonance spectroscopy studies of bromobenzene-induced liver damage in the rat. Magnetic resonance imaging, 1992, Volume: 10, Issue:2 Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains	1992
Activation and toxicity of bromobenzene in nasal tissue in mice. Archives of toxicology, 1990, Volume: 64, Issue:1 Topics: Animals; Autoradiography; Bromobenzenes; Chemical and Drug Induced Liver Injury; Female; Liver; Maxillary Sinus; Mice; Mice, Inbred C57BL; Nasal Mucosa; Olfactory Mucosa	1990
Cytoprotective effect of the prostacyclin derivative iloprost against liver cell death induced by the hepatotoxins carbon tetrachloride and bromobenzene. Klinische Wochenschrift, 1986, Volume: 64 Suppl 7 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Epoprostenol; Iloprost; L-Lactate Dehydrogenase; Liver Diseases; Male; Necrosis; Rats	1986
The effect of some hepatotoxins on the sulphoxidation of cimetidine in rat. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 83, Issue:2 Topics: 1-Propanol; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cimetidine; Propanols; Rats; Rats, Inbred Strains; Sulfoxides; Thioacetamide	1986
Antagonism of bromobenzene-induced hepatotoxicity by phentolamine: evidence for a metabolism-independent intervention. Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Liver; Liver Diseases; Male; Mice; Microsomes, Liver; Phentolamine	1988
Antagonism of bromobenzene-induced hepatotoxicity by the alpha-adrenergic blocking agents, phentolamine and idazoxan. Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1 Topics: Adrenergic alpha-Antagonists; Alanine Transaminase; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Epinephrine; Glutathione; Idazoxan; Liver Diseases; Male; Mice; Necrosis; Norepinephrine; Phentolamine; Time Factors	1988
Significance of alcohol dehydrogenase (ADH) as a marker of hepatic centrilobular injury: a biochemical and immunohistochemical study. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1 Topics: Alanine Transaminase; Alcohol Dehydrogenase; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Rats; Rats, Inbred Strains	1987
A dynamic liver culture system: a tool for studying chemical biotransformation and toxicity. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1987, Volume: 11 Topics: 1-Propanol; Adenosine Triphosphate; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Culture Techniques; Cytochrome P-450 Enzyme System; Hydrocarbons, Chlorinated; Liver; Liver Diseases; Male; Potassium; Propanols; Protein Biosynthesis; Rats; Rats, Inbred F344; Rats, Inbred Strains	1987
Influence of the vitamin D hormonal status on the hepatic response to bromobenzene. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Calcitriol; Calcium; Chemical and Drug Induced Liver Injury; Hypocalcemia; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Vitamin D Deficiency	1987
Effect of a cysteine prodrug, L-2-oxothiazolidine-4-carboxylic acid, on the metabolism and toxicity of bromobenzene: an acute study. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:5 Topics: Acetylcysteine; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Mice; Phenols; Sulfates; Transaminases	1987
Metabolism of bromobenzene. Analytical chemical and structural problems associated with studies of the metabolism of a model aromatic compound. Journal of chromatography, 1987, Jul-24, Volume: 399 Topics: Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Kidney Diseases; Oxidation-Reduction; Phenols; Rats; Species Specificity	1987
Effect of bilirubin and bile acids on biliary phospholipid secretion during bromobenzene-induced hepatic injury in the rabbit. Experimental pathology, 1987, Volume: 32, Issue:2 Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Bromobenzenes; Chemical and Drug Induced Liver Injury; Glycodeoxycholic Acid; Liver Diseases; Male; Phospholipids; Rabbits	1987
Aminopyrine breath test and zonal hepatic damage in rats. Pharmacology, 1985, Volume: 31, Issue:6 Topics: Aminopyrine; Animals; Aspartate Aminotransferases; Breath Tests; Bromobenzenes; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Male; Mixed Function Oxygenases; Propanols; Rats; Rats, Inbred Strains	1985
Influence of mercuric chloride on the metabolism and hepatotoxicity of bromobenzene in rats. Environmental research, 1986, Volume: 39, Issue:1 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Catechols; Chemical and Drug Induced Liver Injury; Drug Interactions; Male; Mercuric Chloride; Microsomes, Liver; Phenols; Rats; Rats, Inbred Strains	1986
Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis. The American journal of pathology, 1985, Volume: 118, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chromans; Glutathione; Iodobenzenes; Lipid Peroxides; Liver; Liver Diseases; Male; Maleates; Mice; Necrosis; Proteins; Rats; Rats, Inbred Strains	1985
Heterogeneity of rabbit hepatocytes for bile secretion after acinar zone 3 damage induced by bromobenzene. Effect of bilirubin and bile salt infusions. Biochemical pharmacology, 1985, Feb-15, Volume: 34, Issue:4 Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Bromobenzenes; Chemical and Drug Induced Liver Injury; Female; Glycodeoxycholic Acid; Infusions, Parenteral; Liver; Liver Diseases; Male; Rabbits	1985
Amelioration of bromobenzene hepatotoxicity in the male rat by zinc. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Liver Diseases; Male; Microsomes, Liver; Mixed Function Oxygenases; Protein Binding; Rats; Rats, Inbred Strains; Subcellular Fractions; Zinc	1985
Comparative hepatic response to bromobenzene and allyl alcohol in the vitamin D-replete and vitamin D-depleted rat. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2 Topics: 1-Propanol; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; L-Iditol 2-Dehydrogenase; Microsomes, Liver; Mixed Function Oxygenases; Propanols; Rats; Rats, Inbred Strains; Vitamin D; Vitamin D Deficiency	1985