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bromisovalum and Icterus

bromisovalum has been researched along with Icterus in 1 studies

Bromisovalum: A sedative and mild hypnotic with potentially toxic effects.
bromisoval : A racemate comprising equimolar amounts of (R)- and (S)-bromisoval. It was previously used for its hypnotic and sedative properties but the use of bromides is now deprecated due to the possibility of the toxic accumulation of bromine in the body.
2-bromo-N-carbamoyl-3-methylbutanamide : An N-acylurea that is urea in which one of the hydrogens is replaced by a 2-bromo-3-methybutanoyl group.

Research Excerpts

ExcerptRelevanceReference
"Stereoselectivity of glutathione conjugation was studied in unanesthetized normal and congenitally jaundiced rats (Groningen Yellow), using the separate enantiomers of alpha-bromoisovalerylurea (BIU) as substrates."7.67Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats. ( Kuipers, F; Mulder, GJ; Polhuijs, M; Vonk, RJ, 1989)
"Stereoselectivity of glutathione conjugation was studied in unanesthetized normal and congenitally jaundiced rats (Groningen Yellow), using the separate enantiomers of alpha-bromoisovalerylurea (BIU) as substrates."3.67Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats. ( Kuipers, F; Mulder, GJ; Polhuijs, M; Vonk, RJ, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Polhuijs, M1
Kuipers, F1
Vonk, RJ1
Mulder, GJ1

Other Studies

1 other study available for bromisovalum and Icterus

ArticleYear
Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3

    Topics: Animals; Bile; Bromisovalum; Glutathione; Glutathione Transferase; Jaundice; Liver; Male; Rats; Rats

1989