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bromhexine and Respiratory Distress Syndrome

bromhexine has been researched along with Respiratory Distress Syndrome in 5 studies

Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).

Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"The authors study the changes in cardiopulmonary function after application of bromhexine metabolite VIII (NA 872) in an animal model of adult respiratory distress syndrome (ARDS) and bromhexine glucose solution (BGS) in ARDS patients."7.66Application of bromhexine metabolite VIII (NA 872) and bromhexine-glucose in treatment of adult respiratory distress syndrome; experimental and clinical results . ( Dauberschmidt, R; Frenzke, H; Hieronymi, U; Kuckelt, W; Lachmann, B; Meyer, M; Mrochen, H; Scharfenberg, J; Winsel, K, 1980)
"Ambroxol, a drug capable of elevating the phospholipid content in healthy rabbit lungs, was tested on two models of experimental lung injury, lung changes in sepsis induced by a peritonitis and in bromcarbamide intoxication."3.67Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders. ( Müller, B; von Wichert, P; Wilke, A, 1987)
"The authors study the changes in cardiopulmonary function after application of bromhexine metabolite VIII (NA 872) in an animal model of adult respiratory distress syndrome (ARDS) and bromhexine glucose solution (BGS) in ARDS patients."3.66Application of bromhexine metabolite VIII (NA 872) and bromhexine-glucose in treatment of adult respiratory distress syndrome; experimental and clinical results . ( Dauberschmidt, R; Frenzke, H; Hieronymi, U; Kuckelt, W; Lachmann, B; Meyer, M; Mrochen, H; Scharfenberg, J; Winsel, K, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Lipworth, B1
Chan, R1
Lipworth, S1
RuiWen Kuo, C1
Dauberschmidt, R2
Kuckelt, W2
Bender, V1
Hieronymi, U2
Mrochen, H2
Winsel, K2
Zinsmeyer, J1
Meyer, M2
Scharfenberg, J1
Lachmann, B1
Frenzke, H1
Disse, BG1
Wilke, A1
Müller, B1
von Wichert, P1

Reviews

1 review available for bromhexine and Respiratory Distress Syndrome

ArticleYear
The pharmacology of ambroxol--review and new results.
    European journal of respiratory diseases. Supplement, 1987, Volume: 153

    Topics: Airway Resistance; Ambroxol; Animals; Bromhexine; Bronchitis; Chronic Disease; Humans; Infant, Newbo

1987

Other Studies

4 other studies available for bromhexine and Respiratory Distress Syndrome

ArticleYear
Weathering the Cytokine Storm in Susceptible Patients with Severe SARS-CoV-2 Infection.
    The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Angiotensin-Converting Enzyme Inhi

2020
Effects of bromhexine metabolite VIII (NA 872) in an animal model of the respiratory distress syndrome.
    Bulletin europeen de physiopathologie respiratoire, 1980, Volume: 16, Issue:2

    Topics: Ambroxol; Animals; Blood Circulation; Bromhexine; Carbon Dioxide; Disease Models, Animal; Lactates;

1980
Application of bromhexine metabolite VIII (NA 872) and bromhexine-glucose in treatment of adult respiratory distress syndrome; experimental and clinical results .
    Respiration; international review of thoracic diseases, 1980, Volume: 39, Issue:5

    Topics: Animals; Bromhexine; Humans; Lung; Lung Compliance; Respiration; Respiratory Dead Space; Respiratory

1980
Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders.
    Respiration; international review of thoracic diseases, 1987, Volume: 52, Issue:2

    Topics: Ambroxol; Animals; Bromhexine; Choline; Fatty Acids; Female; Lung; Lung Diseases; Male; Peritonitis;

1987