bromhexine has been researched along with Pulmonary Fibrosis in 2 studies
Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary fibrosis is the end point of progressive functional disorder of respiratory mechanism and alveolo-capillary gas exchanges." | 2.66 | Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention. ( Butti, G; Gaetani, P; Knerich, R; Rossi, A; Silvani, V; Spanu, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luisetti, M | 1 |
| Peona, V | 1 |
| Salmona, M | 1 |
| Pagnoni, AM | 1 |
| Villani, F | 1 |
| Knerich, R | 2 |
| Genghini, M | 1 |
| Abbà, L | 1 |
| Pozzi, E | 1 |
| Gaetani, P | 1 |
| Silvani, V | 1 |
| Butti, G | 1 |
| Spanu, G | 1 |
| Rossi, A | 1 |
1 trial available for bromhexine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention.
Topics: Adult; Aged; Ambroxol; Brain Neoplasms; Bromhexine; Carmustine; Clinical Trials as Topic; Double-Bli | 1987 |
1 other study available for bromhexine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; | 1986 |