bromhexine has been researched along with Otitis Media with Effusion in 8 studies
Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As one of the causes of persistence of otitis media with effusion is reputed to be the viscidity of the mucoid effusion in the middle ear, a double-blind drug trial with a mucolytic agent, bromhexine hydrochloride, was carried out." | 9.05 | Bromhexine for otitis media with effusion. ( Roydhouse, N, 1981) |
| "In a double blind randomised trial of 95 children aged 3-8 years with otitis media with effusion (OME), the efficacy of the mucolytic agent bromhexine hydrochloride (Bisolvon) was compared with a placebo." | 9.05 | Bromhexine in the treatment of otitis media with effusion. ( Allison, RS; Guy, AM; Stewart, IA; Thomson, NJ, 1985) |
| "As one of the causes of persistence of otitis media with effusion is reputed to be the viscidity of the mucoid effusion in the middle ear, a double-blind drug trial with a mucolytic agent, bromhexine hydrochloride, was carried out." | 5.05 | Bromhexine for otitis media with effusion. ( Roydhouse, N, 1981) |
| "In a double blind randomised trial of 95 children aged 3-8 years with otitis media with effusion (OME), the efficacy of the mucolytic agent bromhexine hydrochloride (Bisolvon) was compared with a placebo." | 5.05 | Bromhexine in the treatment of otitis media with effusion. ( Allison, RS; Guy, AM; Stewart, IA; Thomson, NJ, 1985) |
| "Much controversy still exists in the treatment of otitis media with effusion." | 2.66 | The negative effects of mucolytics in otitis media with effusion. ( van der Merwe, J; Wagenfeld, DJ, 1987) |
| "Treatment was ambroxol, a drug that changes the bronchial secretions and promotes surfactant synthesis." | 2.66 | Multicenter study on the treatment of secretory otitis media with ambroxol. Importance of a surface-tension-lowering substance. ( Passàli, D; Zavattini, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pekarskiĭ, SI | 1 |
| Romanet, P | 1 |
| Roydhouse, N | 1 |
| van der Merwe, J | 1 |
| Wagenfeld, DJ | 1 |
| Sartoris, A | 1 |
| Calero del Castillo, JB | 1 |
| Pérez Martínez, F | 1 |
| Piqueras Pérez, F | 1 |
| Redondo Luciáñez, ER | 1 |
| Passàli, D | 1 |
| Zavattini, G | 1 |
| Stewart, IA | 1 |
| Guy, AM | 1 |
| Allison, RS | 1 |
| Thomson, NJ | 1 |
5 trials available for bromhexine and Otitis Media with Effusion
| Article | Year |
|---|---|
Bromhexine for otitis media with effusion.
Topics: Adenoids; Adolescent; Bromhexine; Child; Clinical Trials as Topic; Double-Blind Method; Expectorants | 1981 |
The negative effects of mucolytics in otitis media with effusion.
Topics: Acoustic Impedance Tests; Bromhexine; Child; Child, Preschool; Clinical Trials as Topic; Double-Blin | 1987 |
[Treatment of secretory otitis media with ambroxol].
Topics: Acoustic Impedance Tests; Adolescent; Adult; Ambroxol; Audiometry; Bromhexine; Child; Double-Blind M | 1987 |
Multicenter study on the treatment of secretory otitis media with ambroxol. Importance of a surface-tension-lowering substance.
Topics: Adult; Ambroxol; Audiometry; Bromhexine; Child; Double-Blind Method; Female; Humans; Male; Otitis Me | 1987 |
Bromhexine in the treatment of otitis media with effusion.
Topics: Bromhexine; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Administrat | 1985 |
3 other studies available for bromhexine and Otitis Media with Effusion
| Article | Year |
|---|---|
[Use of mucoregulating drugs in combined therapy of exudative otitis media].
Topics: Adolescent; Adult; Bromhexine; Child; Combined Modality Therapy; Expectorants; Female; Humans; Male; | 2003 |
[Bisolvon trial in serous otitis with closed tympanum in children].
Topics: Bromhexine; Child; Child, Preschool; Drainage; Ear, Middle; Expectorants; Humans; Infant; Otitis Med | 1983 |
[Incorporation of a stimulant of the synthesis and secretion of pulmonary surfactant (ambroxol) in the medical treatment of serous otitis].
Topics: Acoustic Impedance Tests; Acute Disease; Adolescent; Adult; Ambroxol; Bromhexine; Child; Child, Pres | 1988 |