bromhexine has been researched along with Obstructive Lung Diseases in 25 studies
Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A comparison between the action of Ambroxol and Acetylcysteine was carried out in 28 children aged 2 to 13 (mean 7 years 3 months) affected with spastic bronchitis." | 9.06 | [A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children]. ( Baldini, G; Gucci, M; Memmini, C; Tarò, D, 1989) |
| "Ambroxol was associated with a 25% reduction of the average bronchial flow resistance." | 6.64 | [Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)]. ( Niemeyer, K; Wiessmann, KJ, 1978) |
| "A comparison between the action of Ambroxol and Acetylcysteine was carried out in 28 children aged 2 to 13 (mean 7 years 3 months) affected with spastic bronchitis." | 5.06 | [A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children]. ( Baldini, G; Gucci, M; Memmini, C; Tarò, D, 1989) |
| "The clinical activity of trans-4-[(2-amino-3,5-dibromo-benzyl)-amino]-cyclohexanol-hydrochloride (ambroxol, NA 872) as well as its influence on lung function was examined in a total of 63 patients (34 suffering from silicosis, 28 from chronic obstructive bronchitis and 1 from cryptococcosis)." | 3.66 | [Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)]. ( Curti, PC; Renovanz, HD, 1978) |
| "Ambroxol was effective in only 1 of 5 tested lung areas and did not prove to enhance whole lung clearance significantly." | 2.65 | Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD. ( Dorow, P; Felix, R; Weiss, T, 1981) |
| "Ambroxol was associated with a 25% reduction of the average bronchial flow resistance." | 2.64 | [Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)]. ( Niemeyer, K; Wiessmann, KJ, 1978) |
| " The drug was given orally in a dosage of 100 mg BID for ten days." | 1.27 | Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases. ( Primbs, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (88.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Medici, TC | 1 |
| Ramer, P | 1 |
| Hatt, RR | 1 |
| Unger, S | 1 |
| Misra, MP | 1 |
| Tiwari, UC | 1 |
| Chaubal, CC | 1 |
| Galhotra, R | 1 |
| Lobello, R | 1 |
| Marzano, LA | 1 |
| Corcione, F | 1 |
| La Manna, S | 1 |
| Cristinzio, G | 1 |
| De Ascentis, G | 1 |
| Scarafile, P | 1 |
| Turco, P | 1 |
| Pomari, C | 1 |
| Zoccatelli, O | 1 |
| Trevisan, F | 1 |
| Carloni, C | 1 |
| Dal Negro, RW | 1 |
| Camner, P | 1 |
| Weiss, T | 4 |
| Dorow, P | 4 |
| Felix, R | 3 |
| Král, B | 1 |
| Ellás, J | 1 |
| Rozánek, P | 1 |
| Jirkal, J | 1 |
| Tilser, P | 1 |
| Serrano, J | 1 |
| Sanchis, J | 1 |
| Wiessmann, KJ | 1 |
| Niemeyer, K | 1 |
| Clini, V | 1 |
| Guadagni, L | 1 |
| Zennaro, M | 1 |
| Fumagalli, G | 1 |
| Curti, PC | 1 |
| Renovanz, HD | 1 |
| Mészáros, L | 1 |
| Molnár, B | 1 |
| Beke, M | 1 |
| Bury, T | 1 |
| Corhay, JL | 1 |
| Radermecker, MF | 1 |
| Bavaro, P | 1 |
| Biscari, P | 1 |
| Baldini, G | 1 |
| Gucci, M | 1 |
| Tarò, D | 1 |
| Memmini, C | 1 |
| Valenti, S | 1 |
| Marenco, G | 1 |
| Lunichkina, IV | 1 |
| Solopov, VN | 1 |
| Schmutzler, H | 1 |
| Gupta, SK | 1 |
| Misra, K | 1 |
| Primbs, K | 1 |
| Watson, EW | 2 |
| Aylward, M | 1 |
1 review available for bromhexine and Obstructive Lung Diseases
| Article | Year |
|---|---|
[Usefulness of mucoactive drugs in respiratory diseases].
Topics: Acetylcysteine; Ambroxol; Bromhexine; Bronchiectasis; Bronchitis; Cystic Fibrosis; Deoxyribonuclease | 1998 |
13 trials available for bromhexine and Obstructive Lung Diseases
| Article | Year |
|---|---|
Double blind crossover randomised study of bromhexine in chronic obstructive airway disease.
Topics: Adult; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lung Diseases, Obs | 1984 |
Studies on the removal of inhaled particles from the lungs by voluntary coughing.
Topics: Aerosols; Bromhexine; Cilia; Clinical Trials as Topic; Cough; Double-Blind Method; Humans; Lung; Lun | 1981 |
Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD.
Topics: Albumins; Ambroxol; Bromhexine; Cilia; Clenbuterol; Clinical Trials as Topic; Double-Blind Method; E | 1981 |
Clinical study on Lasolvan in chronic obstructive pulmonary disease.
Topics: Ambroxol; Bromhexine; Clinical Trials as Topic; Female; Humans; Lung Diseases, Obstructive; Male | 1981 |
[The effect of ambroxol on mucociliary clearance (author's transl)].
Topics: Ambroxol; Bromhexine; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Male; Metabol | 1981 |
[Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)].
Topics: Adult; Aged; Airway Resistance; Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Clinical Trials a | 1978 |
[Mucolytic acitivity of bromhexine guaiacol combination in chronic bronchopneumopathy patients].
Topics: Adult; Bromhexine; Bronchial Diseases; Clinical Trials as Topic; Drug Combinations; Guaiacol; Humans | 1979 |
Effect of Paxirasol aerosol on the clinical condition and objective functional respiratory parameters of obstructive respiratory tract disease patients.
Topics: Administration, Inhalation; Bromhexine; Female; Humans; Lung Diseases, Obstructive; Middle Aged; Res | 1991 |
[A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children].
Topics: Acetylcysteine; Adolescent; Ambroxol; Bromhexine; Bronchitis; Child; Child, Preschool; Clinical Tria | 1989 |
Italian multicenter study on the treatment of chronic obstructive lung disease with bromhexine. A double-blind placebo-controlled trial.
Topics: Adult; Aged; Bromhexine; Double-Blind Method; Female; Humans; Italy; Lung Diseases, Obstructive; Mal | 1989 |
[Modification of mucociliary clearance by a combination of theophylline with ambroxol and of ambroxol in monotherapy].
Topics: Adult; Aerosols; Ambroxol; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Humans; Lung D | 1988 |
[Effect of a secretolytic and a combination of pinene, limonene and cineole on mucociliary clearance in patients with chronic obstructive pulmonary disease].
Topics: Adult; Aged; Ambroxol; Bromhexine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Lun | 1987 |
A between-patient, double-blind comparison of S-carboxymethylcysteine and bromhexine in chronic obstructive bronchitis.
Topics: Administration, Oral; Adult; Aged; Amino Acids, Dicarboxylic; Amino Acids, Sulfur; Bromhexine; Bronc | 1973 |
11 other studies available for bromhexine and Obstructive Lung Diseases
| Article | Year |
|---|---|
[Longterm treatment in chronic nonspecific airway diseases (author's transl)].
Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Bromhexine; Bronchi; Bronchial Spasm; Humans; Lu | 1982 |
[Bromhexine in the prevention of postoperative complications in digestive surgery].
Topics: Bromhexine; Digestive System Diseases; Double-Blind Method; Humans; Lung Diseases, Obstructive; Post | 1983 |
Therapy for intercurrent respiratory infections in COLD patients: report on 200 patients.
Topics: Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Bromhexine; Cephalexin; Drug Therapy, Combi | 1983 |
[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)].
Topics: Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Cryptococcosis; Humans; Lung Diseases; Lung Disea | 1978 |
[Kinetics of mucus].
Topics: Acetylcysteine; Antitussive Agents; Bromhexine; Cough; Expectorants; Humans; Lung Diseases, Obstruct | 1990 |
[Prophylaxis and treatment of bronchopulmonary complications with ambroxol administered by infusion in elderly patients undergoing surgery].
Topics: Adult; Aged; Aged, 80 and over; Ambroxol; Bromhexine; Drug Evaluation; Female; Humans; Infusions, In | 1989 |
[Peroral therapy with expectorants].
Topics: Administration, Oral; Ambroxol; Bromhexine; Ciliary Motility Disorders; Expectorants; Humans; Lung D | 1988 |
Bromhexine and COPD.
Topics: Bromhexine; Humans; Lung Diseases, Obstructive; Maximal Expiratory Flow Rate; Respiratory Function T | 1985 |
Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases.
Topics: Aged; Ambroxol; Bromhexine; Drug Evaluation; Female; Humans; Lung Diseases, Obstructive; Male; Theop | 1985 |
Letter: Bisolvon in chronic respiratory disease.
Topics: Adult; Aged; Bromhexine; Child; Chronic Disease; Dyspnea; Female; Humans; Lung Diseases, Obstructive | 1974 |
Letter: "Bisolvon" in chronic respiratory disease.
Topics: Bromhexine; Chronic Disease; Humans; Lung Diseases, Obstructive; Male | 1974 |