bromhexine has been researched along with Lung Diseases in 12 studies
Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Lung Diseases: Pathological processes involving any part of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With regard to a possible therapeutic application in this context the effect of bromhexine and ambroxol on the activity of AM of of guinea-pigs and of patients with lung diseases was investigated." | 3.67 | [Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid]. ( Eckert, H; Grollmuss, H; Unger, U; Winsel, K, 1985) |
| "Ambroxol, a drug capable of elevating the phospholipid content in healthy rabbit lungs, was tested on two models of experimental lung injury, lung changes in sepsis induced by a peritonitis and in bromcarbamide intoxication." | 3.67 | Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders. ( Müller, B; von Wichert, P; Wilke, A, 1987) |
| "The clinical activity of trans-4-[(2-amino-3,5-dibromo-benzyl)-amino]-cyclohexanol-hydrochloride (ambroxol, NA 872) as well as its influence on lung function was examined in a total of 63 patients (34 suffering from silicosis, 28 from chronic obstructive bronchitis and 1 from cryptococcosis)." | 3.66 | [Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)]. ( Curti, PC; Renovanz, HD, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deretic, V | 1 |
| Timmins, GS | 1 |
| Shimura, S | 1 |
| Okubo, T | 1 |
| Maeda, S | 1 |
| Aoki, T | 1 |
| Tomioka, M | 1 |
| Shindo, Y | 1 |
| Takishima, T | 1 |
| Umeya, K | 1 |
| Curti, PC | 1 |
| Renovanz, HD | 1 |
| Komarov, FI | 1 |
| Daniliak, IG | 1 |
| Guliaeva, FE | 1 |
| Lobello, R | 1 |
| Luisetti, M | 1 |
| Peona, V | 1 |
| Salmona, M | 1 |
| Pagnoni, AM | 1 |
| Villani, F | 1 |
| Knerich, R | 1 |
| Genghini, M | 1 |
| Abbà, L | 1 |
| Pozzi, E | 1 |
| Winsel, K | 1 |
| Grollmuss, H | 1 |
| Unger, U | 1 |
| Eckert, H | 1 |
| Solopov, VN | 1 |
| Kolganova, NA | 1 |
| Romanini, BM | 1 |
| Sandri, MG | 1 |
| Tosi, M | 1 |
| Mezzetti, M | 1 |
| Mazzetti, A | 1 |
| Wilke, A | 1 |
| Müller, B | 1 |
| von Wichert, P | 1 |
| Banna, P | 1 |
| Marcello, MF | 1 |
| Murabito, R | 1 |
| Saggio, A | 1 |
| Riggi, M | 1 |
| Cinà, C | 1 |
| Latteri, S | 1 |
1 review available for bromhexine and Lung Diseases
| Article | Year |
|---|---|
Enhancement of lung levels of antibiotics by ambroxol and bromhexine.
Topics: Ambroxol; Animals; Anti-Bacterial Agents; Bacterial Infections; Bromhexine; Drug Resistance, Bacteri | 2019 |
4 trials available for bromhexine and Lung Diseases
| Article | Year |
|---|---|
Effect of expectorants on relaxation behavior of sputum viscoelasticity in vivo.
Topics: Adult; Aged; Ambroxol; Bromhexine; Chymotrypsin; Elasticity; Expectorants; Female; Humans; Lung Dise | 1983 |
[Use of bisolvon in nonspecific diseases of the respiratory organs].
Topics: Antitussive Agents; Bromhexine; Bronchial Diseases; Clinical Trials as Topic; Drug Evaluation; Human | 1975 |
[Postoperative pulmonary complications following abdominal surgery. Study on the preventive use of a bronchosecretolytic agent associated with an antibiotic].
Topics: Abdomen; Adult; Aged; Bromhexine; Bronchial Spasm; Bronchitis; Bronchopneumonia; Clinical Trials as | 1975 |
Ambroxol for prophylaxis and treatment of bronchopulmonary complications after chest surgery.
Topics: Adult; Aged; Ambroxol; Bromhexine; Bronchial Diseases; Clinical Trials as Topic; Double-Blind Method | 1986 |
7 other studies available for bromhexine and Lung Diseases
| Article | Year |
|---|---|
[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)].
Topics: Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Cryptococcosis; Humans; Lung Diseases; Lung Disea | 1978 |
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; | 1986 |
[Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid].
Topics: Ambroxol; Animals; Arachidonic Acid; Arachidonic Acids; Bromhexine; Guinea Pigs; Luminescent Measure | 1985 |
[Effect of lasolvan on mucociliary transport in patients with chronic nonspecific lung diseases].
Topics: Adhesiveness; Ambroxol; Bromhexine; Chronic Disease; Drug Evaluation; Humans; Lung Diseases; Mucocil | 1988 |
New aspects in the treatment of pulmonary and upper airways diseases. Proceedings of the satellite symposium to the 4th Congress of the European Society of Pneumology. Milano and Stresa, September 23-28, 1985.
Topics: Ambroxol; Animals; Bromhexine; Humans; Lung Diseases; Respiratory Tract Diseases | 1987 |
Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders.
Topics: Ambroxol; Animals; Bromhexine; Choline; Fatty Acids; Female; Lung; Lung Diseases; Male; Peritonitis; | 1987 |
Ultrastructural changes of the pulmonary parenchyma after experimentally induced endotoxic shock in dogs with and without drug protection.
Topics: Animals; Bromhexine; Cytidine Diphosphate Choline; Dogs; Lung; Lung Diseases; Pulmonary Surfactants; | 1985 |