bromhexine has been researched along with Infections, Respiratory in 15 studies
Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
| Excerpt | Relevance | Reference |
|---|---|---|
| "03 mg/ml eleutherosides B and E), bromhexine hydrochloride (24 mg/30 ml/day) and PL on cough and blood markers." | 5.20 | Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extracts in patients with acute upper respiratory tract infection: A comparative, randomized, double-blind, placebo-controlled study. ( Barth, A; Hovhannisyan, A; Jamalyan, K; Narimanyan, M, 2015) |
| "A multicenter double-blind randomized trial was performed in 22 teaching hospitals to compare the clinical effectiveness of the combination of amoxicillin (CAS 26787-78-0) plus bromhexine (CAS 3572-43-8) versus amoxicillin alone given 4 times a day for 5 to 7 days in the treatment of clinically diagnosed community-acquired bacterial lower respiratory tract infections." | 5.08 | Clinical effectiveness of a combination of bromhexine and amoxicillin in lower respiratory tract infection. A randomized controlled trial. ( Dantes, RB; Roa, CC, 1995) |
| "Results." | 2.79 | [Therapeutic modalities for the management of cough associated with acute respiratory viral infection, effective in an otolaryngologist's practice]. ( Korostelev, SA; Mitiuk, AM; Ovchinnikov, AI; Paniakina, MA, 2014) |
| " Ascoril expectorant caused no adverse reactions and was well tolerated by the patients." | 2.78 | [Results of international multicentre non-interventional clinical study of the effectiveness and safety of ascoril expectorant for the treatment of cough in Kazakhstan and Uzbekistan]. ( Abuova, GT; An, ÉA; Ermekbaeva, BA; Guliaev, AE; Nurgozhin, TS; Zhaugasheva, SK, 2013) |
| "The purpose of the present clinical studies was to determine the clinical efficacy of a combined parenteral and oral treatment with Bisolvon in combination with antibiotics in bovines suffering from acute respiratory disease." | 2.69 | [Treatment of acute respiratory tract diseases in cattle with Bisolvon in combination with either enrofloxacin, cefquinome, ceftiofur or florfenicol]. ( Hamel, U; Philipp, H; Quirke, JF; Schmidt, H, 1998) |
| "Symptoms of mild acute respiratory infections are commonly treated with over-the-counter products like ambroxol, bromhexine, and N-acetyl cysteine, as well as of thyme and pelargonium extracts today." | 1.56 | Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts. ( Döring, K; Schmidtke, M; Walther, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Walther, C | 1 |
| Döring, K | 1 |
| Schmidtke, M | 1 |
| Nurgozhin, TS | 1 |
| Guliaev, AE | 1 |
| Ermekbaeva, BA | 1 |
| Zhaugasheva, SK | 1 |
| Abuova, GT | 1 |
| An, ÉA | 1 |
| Ovchinnikov, AI | 1 |
| Paniakina, MA | 1 |
| Korostelev, SA | 1 |
| Mitiuk, AM | 1 |
| Barth, A | 1 |
| Hovhannisyan, A | 1 |
| Jamalyan, K | 1 |
| Narimanyan, M | 1 |
| KLEVER, R | 1 |
| WURZEL, G | 1 |
| Palmieri, B | 1 |
| Monni, S | 1 |
| Misella, A | 1 |
| Cogni, P | 1 |
| Turco, P | 1 |
| Pomari, C | 1 |
| Zoccatelli, O | 1 |
| Trevisan, F | 1 |
| Carloni, C | 1 |
| Dal Negro, RW | 1 |
| Bergogne-Berezin, E | 1 |
| Pierre, J | 1 |
| Dournovo, P | 1 |
| Vendemmia, S | 1 |
| Maurino, G | 1 |
| Goglia, R | 1 |
| Della Peruta, A | 1 |
| Roa, CC | 1 |
| Dantes, RB | 1 |
| Schmidt, H | 1 |
| Philipp, H | 1 |
| Hamel, U | 1 |
| Quirke, JF | 1 |
| von Harnack, GA | 1 |
| Lauriello, G | 1 |
| Giella, D | 1 |
| Berra, A | 1 |
| Matonti, V | 1 |
| Hackett, IJ | 1 |
| Renovanz, HD | 1 |
8 trials available for bromhexine and Infections, Respiratory
| Article | Year |
|---|---|
[Results of international multicentre non-interventional clinical study of the effectiveness and safety of ascoril expectorant for the treatment of cough in Kazakhstan and Uzbekistan].
Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Bromhexine; Child, Preschoo | 2013 |
[Therapeutic modalities for the management of cough associated with acute respiratory viral infection, effective in an otolaryngologist's practice].
Topics: Acute Disease; Adult; Albuterol; Ambroxol; Bromhexine; Bronchodilator Agents; Cough; Drug Combinatio | 2014 |
Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extracts in patients with acute upper respiratory tract infection: A comparative, randomized, double-blind, placebo-controlled study.
Topics: Adult; Antitussive Agents; Bromhexine; Common Cold; Cough; Double-Blind Method; Echinacea; Eleuthero | 2015 |
[Effect of a secretolytic agent (bromhexine) on the penetration of erythromycin into bronchial secretions].
Topics: Bromhexine; Clinical Trials as Topic; Double-Blind Method; Erythromycin; Humans; Mucus; Respiratory | 1982 |
Clinical effectiveness of a combination of bromhexine and amoxicillin in lower respiratory tract infection. A randomized controlled trial.
Topics: Adolescent; Adult; Amoxicillin; Bromhexine; Community-Acquired Infections; Double-Blind Method; Drug | 1995 |
[Treatment of acute respiratory tract diseases in cattle with Bisolvon in combination with either enrofloxacin, cefquinome, ceftiofur or florfenicol].
Topics: Acute Disease; Administration, Oral; Animals; Anti-Infective Agents; Bromhexine; Cattle; Cattle Dise | 1998 |
[Combination of oral bacterial vaccines and antibiotics in acute recurrent respiratory infections].
Topics: Acute Disease; Administration, Oral; Adult; Ambroxol; Bacterial Vaccines; Bromhexine; Ceftriaxone; C | 1990 |
[Pharmacokinetics, drug availability and clinical pharmacology of bromhexine].
Topics: Absorption; Adult; Aged; Animals; Autoradiography; Bromhexine; Carbon Isotopes; Clinical Trials as T | 1973 |
7 other studies available for bromhexine and Infections, Respiratory
| Article | Year |
|---|---|
Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts.
Topics: Acetylcysteine; Ambroxol; Animals; Bromhexine; Dogs; HeLa Cells; Humans; Influenza A virus; Madin Da | 2020 |
[TREATMENT OF CATARRHAL IRRITATION SYMTOMS IN THE COURSE OF INFLUENZA INFECTIONS WITH BISOLVON-GRIBLETS].
Topics: Bromhexine; Bronchodilator Agents; Common Cold; Humans; Influenza, Human; Respiratory Tract Infectio | 1965 |
Therapeutic and prophylactic effects of cephalexin and bromhexine in respiratory tract complications of abdominal surgery.
Topics: Abdomen; Adult; Aged; Bacterial Infections; Bromhexine; Cephalexin; Drug Therapy, Combination; Femal | 1983 |
Therapy for intercurrent respiratory infections in COLD patients: report on 200 patients.
Topics: Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Bromhexine; Cephalexin; Drug Therapy, Combi | 1983 |
[Clinical study of the properties of Bisolvon in the therapy of respiratory diseases in children].
Topics: Adolescent; Asthma; Bromhexine; Child; Child, Preschool; Expectorants; Humans; Infant; Laryngitis; R | 1981 |
[Indication for drug therapy].
Topics: Adolescent; Age Factors; Analgesics; Antitussive Agents; Asthma; Bromhexine; Child; Child, Preschool | 1977 |
Intratracheal treatment.
Topics: Animals; Anti-Bacterial Agents; Bromhexine; Respiratory Tract Infections | 1988 |