Page last updated: 2024-10-23

bromhexine and Disease Models, Animal

bromhexine has been researched along with Disease Models, Animal in 5 studies

Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
bromhexine : A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" Thus a stimulation of the mucociliary transport rate by the other major pharmacodynamic mechanisms, secretagogue activity and stimulation of pulmonary surfactant, has to be considered."1.27Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments. ( Disse, BG; Ziegler, HW, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Dauberschmidt, R1
Kuckelt, W1
Bender, V1
Hieronymi, U1
Mrochen, H1
Winsel, K1
Zinsmeyer, J1
Meyer, M1
Koyuncu, M1
Yilmaz, M1
Yalçin, S1
Metin, N1
Gündüz, S1
Karataş, E1
Prause, JU1
Elling, F1
Jensen, OA1
Manthorpe, R1
Disse, BG1
Ziegler, HW1

Other Studies

5 other studies available for bromhexine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Effects of bromhexine metabolite VIII (NA 872) in an animal model of the respiratory distress syndrome.
    Bulletin europeen de physiopathologie respiratoire, 1980, Volume: 16, Issue:2

    Topics: Ambroxol; Animals; Blood Circulation; Bromhexine; Carbon Dioxide; Disease Models, Animal; Lactates;

1980
[The existence of sinusitis in rabbits and the use of bromhexine as a mucolytic nose drop in the treatment of sinusitis].
    Mikrobiyoloji bulteni, 1989, Volume: 23, Issue:2

    Topics: Administration, Intranasal; Animals; Bromhexine; Disease Models, Animal; Drainage; Rabbits; Sinusiti

1989
The effect of bromhexine on the kidney lesions in NZB-NZW-F1 mice.
    Scandinavian journal of rheumatology. Supplement, 1986, Volume: 61

    Topics: Animals; Bromhexine; Disease Models, Animal; Glomerulonephritis; Humans; Mice; Sjogren's Syndrome

1986
Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments.
    Respiration; international review of thoracic diseases, 1987, Volume: 51 Suppl 1

    Topics: Albuterol; Ambroxol; Animals; Bromhexine; Cilia; Disease Models, Animal; Guinea Pigs; In Vitro Techn

1987