bromfenacoum and Cardiomyopathies

Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. A 57-year-old woman ingested red-dyed pellets of anticoagulant rodenticide containing difethialone and warfarin as well as tablets of nitrazepam. Although she presented to the hospital in a comatose state, notable pink-colored excreta hinted at the consumption of anticoagulant rodenticide, which led to the early diagnosis of superwarfarin intoxication. Supplementation of large doses of intravenous and oral vitamin K successfully prevented coagulopathy and bleeding. On the other hand, temporary and reversible myocardial suppression was extremely severe, and required the introduction of percutaneous cardiopulmonary support.

Topics: 4-Hydroxycoumarins; Anticoagulants; Cardiomyopathies; Coloring Agents; Female; Humans; Intra-Aortic Balloon Pumping; Middle Aged; Nitrazepam; Rodenticides; Vitamin K; Warfarin