Page last updated: 2024-09-03

brl 44408 and Disease Models, Animal

brl 44408 has been researched along with Disease Models, Animal in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Endo, S; Kozawa, M; Murakami, H; Muto, M; Tadano, T; Tan-No, K; Tsuchiya, M; Yaoita, F1
Elsworth, JD; Jentsch, JD; Roth, RH; Sanchez, D1
Das, P; Dong, W; Goyert, SM; Ji, Y; Miksa, M; Ravikumar, TS; Wang, P; Wu, R; Zhou, M1
Bender, CN; Beyer, CE; Butera, J; Cummons, T; Dwyer, JM; Kowal, D; Leventhal, L; Lu, S; Platt, BJ; Pulicicchio, CM; Rajarao, SJ; Resnick, L; Rizzo, SJ; Rosenzweig-Lipson, S; Schechter, LE; Shilling, AD; Smith, DL; Wang, J; Wantuch, C; Zhang, J; Zhang, MY1
Hernádi, I; Tóth, M; Uzsoki, B1
Alfredson, H; Andersson, G; Backman, LJ; Danielson, P; Fong, G; Scott, A1

Other Studies

7 other study(ies) available for brl 44408 and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep.
    Physiology & behavior, 2018, 03-15, Volume: 186

    Topics: Acetic Acid; Acridines; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileum; Imidazoles; Irritable Bowel Syndrome; Isoindoles; Male; Mice; Piperazines; Receptors, Adrenergic; Sleep Deprivation; Sleep, REM; Visceral Pain

2018
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.
    Brain research, 2008, Dec-30, Volume: 1246

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Disease Models, Animal; Dopamine; Guanfacine; Imidazoles; Isoindoles; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Schizophrenia

2008
Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis.
    PloS one, 2009, Volume: 4, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cecum; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Gene Expression; Heart Rate; Imidazoles; Inflammation; Isoindoles; Kupffer Cells; Ligation; Liver; Male; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Punctures; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; Sepsis; Survival Analysis; Tumor Necrosis Factor-alpha

2009
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:9

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; CHO Cells; Cricetinae; Cricetulus; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Imidazoles; Isoindoles; Male; Mice; Microdialysis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Swimming; Thirst

2010
Novelty response of rats determines the effect of prefrontal alpha-2 adrenoceptor modulation on anxiety.
    Neuroscience letters, 2011, Jul-25, Volume: 499, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Guanfacine; Imidazoles; Individuality; Isoindoles; Male; Maze Learning; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine

2011
Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: Comparison between two model systems.
    Scandinavian journal of medicine & science in sports, 2013, Volume: 23, Issue:6

    Topics: Achilles Tendon; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cell Proliferation; Cells, Cultured; Clonidine; Cumulative Trauma Disorders; Disease Models, Animal; Female; Humans; Imidazoles; In Vitro Techniques; Isoindoles; Rabbits; Receptors, Adrenergic, alpha-2; Tendinopathy; Tyrosine 3-Monooxygenase

2013