Page last updated: 2024-10-26

brl 42810 and Neuralgia, Postherpetic

brl 42810 has been researched along with Neuralgia, Postherpetic in 15 studies

Neuralgia, Postherpetic: Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two forms of the condition preceding the pain are HERPES ZOSTER OTICUS; and HERPES ZOSTER OPHTHALMICUS. Following the healing of the rashes and blisters, the pain sometimes persists.

Research Excerpts

ExcerptRelevanceReference
" According to the results of the network meta-analysis, for the treatment of acute pain, there was no significant difference between oral acyclovir and intravenous acyclovir."5.41A Network Meta-Analysis of Randomized Clinical Trials to Assess the Efficacy and Safety of Antiviral Agents for Immunocompetent Patients with Herpes Zoster-Associated Pain. ( Li, J; Li, X; Liu, Y; Long, X; Xiao, S; Zhang, Y, 2023)
"Herpes zoster has been associated with several complications, of which post-herpetic neuralgia (PHN) is the most common and debilitating."2.49Herpes zoster: diagnostic, therapeutic, and preventive approaches. ( Bader, MS, 2013)
"Herpes zoster is due to the reactivation of the virus causing varicella, called varicella-zoster virus."2.48Effectiveness of antiviral treatment on acute phase of herpes zoster and development of post herpetic neuralgia: review of international publications. ( Bruxelle, J; Pinchinat, S, 2012)
"To review the evidence regarding treatment of herpes zoster (HZ) in the short-term, focusing on the prevention of postherpetic neuralgia (PHN)."2.44Treatment of herpes zoster. ( Eekhof, J; Neven, AK; Opstelten, W; Verheij, T, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's7 (46.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Kong, J1
Wang, H1
Liu, Y2
Xiao, M1
Wang, J1
Liu, Q1
Deng, YX1
Hu, J1
Li, HM1
Xiao, S1
Li, J1
Long, X1
Zhang, Y1
Li, X1
Zografakis, C1
Tiniakos, DG1
Palaiologou, M1
Kouloukoussa, M1
Kittas, C1
Staurianeas, N1
Bader, MS1
Chen, N2
Li, Q2
Yang, J2
Zhou, M2
Zhou, D2
He, L2
Sackel, DJ1
Castano, E1
Cohen, EJ1
Chen, YT1
Wang, HH1
Wang, TJ1
Li, YC1
Chen, TJ1
Zhang, Q1
Cartwright, SL1
Bruxelle, J1
Pinchinat, S1
Wareham, D1
Wassilew, SW1
Pavan-Langston, D1
Opstelten, W1
Eekhof, J1
Neven, AK1
Verheij, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Comparative Open Trial of Occlusive Therapy With a Hydrocolloid or Silicone Versus Conventional Drying Treatment for the Local Care of Acute Lesions Caused by Herpes Zoster.[NCT04258930]36 participants (Anticipated)Interventional2020-02-26Recruiting
Does Repetitive Peripheral Nerve Blocks Vs Single Peripheral Nerve Block Vs Standard Medical Treatment Provide a Better Pain Relief on Zoster Pain at the Acute Phase and Reduce the Risk of Post Herpetic Neuralgia?[NCT04133142]0 participants (Actual)Interventional2020-05-15Withdrawn (stopped due to No enrollement and covid)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for brl 42810 and Neuralgia, Postherpetic

ArticleYear
[Efficacy and safety of different doses of antiviral agents in the treatment of herpes zoster: a meta-analysis].
    Zhonghua yi xue za zhi, 2022, Nov-01, Volume: 102, Issue:40

    Topics: Acyclovir; Antiviral Agents; Blister; Famciclovir; Herpes Zoster; Humans; Neuralgia, Postherpetic; R

2022
A Network Meta-Analysis of Randomized Clinical Trials to Assess the Efficacy and Safety of Antiviral Agents for Immunocompetent Patients with Herpes Zoster-Associated Pain.
    Pain physician, 2023, Volume: 26, Issue:4

    Topics: Acute Pain; Acyclovir; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Network Meta-Analysis;

2023
Herpes zoster: diagnostic, therapeutic, and preventive approaches.
    Postgraduate medicine, 2013, Volume: 125, Issue:5

    Topics: 2-Aminopurine; Acyclovir; Adult; Aged; Aged, 80 and over; Analgesics; Antiviral Agents; Cohort Studi

2013
Antiviral treatment for preventing postherpetic neuralgia.
    The Cochrane database of systematic reviews, 2014, Feb-06, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Humans; Neuralgia, Postherpetic; Randomized

2014
Antiviral treatment for preventing postherpetic neuralgia.
    The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Humans; Neuralgia, Postherpetic; Randomized

2009
Effectiveness of antiviral treatment on acute phase of herpes zoster and development of post herpetic neuralgia: review of international publications.
    Medecine et maladies infectieuses, 2012, Volume: 42, Issue:2

    Topics: 2-Aminopurine; Acute Disease; Acyclovir; Age Factors; Aged; Antiviral Agents; Drug Administration Sc

2012
Postherpetic neuralgia.
    Clinical evidence, 2005, Issue:14

    Topics: 2-Aminopurine; Acyclovir; Amines; Antidepressive Agents, Tricyclic; Antiviral Agents; Arabinofuranos

2005
[Varicella-zoster virus infections--2: Zoster pain -- therapy and prevention].
    MMW Fortschritte der Medizin, 2006, Volume: Spec no.1

    Topics: 2-Aminopurine; Acute Disease; Acyclovir; Administration, Oral; Adult; Age Factors; Analgesics, Non-N

2006
Herpes zoster antivirals and pain management.
    Ophthalmology, 2008, Volume: 115, Issue:2 Suppl

    Topics: 2-Aminopurine; Acyclovir; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tr

2008
Treatment of herpes zoster.
    Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Glucocorticoids; Herpes Zoster; Herpes Zost

2008

Trials

1 trial available for brl 42810 and Neuralgia, Postherpetic

ArticleYear
Increased density of cutaneous nerve fibres in the affected dermatomes after herpes zoster therapy.
    Acta dermato-venereologica, 2014, Volume: 94, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Biomarkers; Biopsy; Bromodeoxyuridine; Famciclovir; Fema

2014

Other Studies

4 other studies available for brl 42810 and Neuralgia, Postherpetic

ArticleYear
14-day famciclovir treatment significantly reduces the incidence of postherpetic neuralgia in elderly patients with herpes zoster.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:11

    Topics: Acute Pain; Aged; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Incidence; Middle Aged; Neur

2022
Physician survey for study of suppressive antiviral treatment to reduce chronic ocular disease and postherpetic neuralgia after herpes zoster ophthalmicus.
    Eye & contact lens, 2014, Volume: 40, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Adult; Antiviral Agents; Attitude of Health Personnel; Chronic Disease; Fa

2014
Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN).
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:3

    Topics: 2-Aminopurine; Adult; Case-Control Studies; Famciclovir; Female; Follow-Up Studies; Herpes Zoster; H

2016
Battling shingles: fine-tune your care.
    The Journal of family practice, 2011, Volume: 60, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Female; Herpes Zoster; Humans; Middle Aged;

2011