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brl 42810 and Liver Failure

brl 42810 has been researched along with Liver Failure in 5 studies

Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"Lamivudine (LMV) is the only nucleoside analogue approved for the treatment of chronic hepatitis B (CHB)."7.72Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure. ( Ayres, A; Bartholomeusz, A; Lam, KC; Lau, G; Lee, JY; Locarnini, S, 2003)
"Lamivudine (LMV) is the only nucleoside analogue approved for the treatment of chronic hepatitis B (CHB)."3.72Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure. ( Ayres, A; Bartholomeusz, A; Lam, KC; Lau, G; Lee, JY; Locarnini, S, 2003)
" Penciclovir is predominantly eliminated unchanged by the kidney, partly by active tubular excretion and has a terminal phase elimination half-life (t1/2 beta) of between 2 and 2."2.39The clinical pharmacokinetics of famciclovir. ( Gill, KS; Wood, MJ, 1996)
"Lamivudine 3 mg/kg was administered on a compassionate-use basis for 14-36 months."1.31Efficacy of lamivudine for the treatment of hepatitis B virus infection after liver transplantation in children. ( Bar-Nathan, N; Ben-Ari, Z; Dinari, G; Mor, E; Shapira, R; Sokal, EM; Tur-Kaspa, R, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ayres, A1
Bartholomeusz, A1
Lau, G1
Lam, KC1
Lee, JY1
Locarnini, S1
Gill, KS1
Wood, MJ1
Piqueras, B1
Salcedo, M1
Bañares, R1
García-Durán, F1
Baños, E1
de Diego, A1
Roldán, P1
Cos, E1
Clemente, G1
Myers, RP1
Chaudhary, R1
Fonseca, K1
Lee, SS1
Shapira, R1
Mor, E1
Bar-Nathan, N1
Sokal, EM1
Tur-Kaspa, R1
Dinari, G1
Ben-Ari, Z1

Reviews

1 review available for brl 42810 and Liver Failure

ArticleYear
The clinical pharmacokinetics of famciclovir.
    Clinical pharmacokinetics, 1996, Volume: 31, Issue:1

    Topics: 2-Aminopurine; Antiviral Agents; Area Under Curve; Famciclovir; Half-Life; Herpes Zoster; Herpesviru

1996

Other Studies

4 other studies available for brl 42810 and Liver Failure

ArticleYear
Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 27, Issue:1

    Topics: 2-Aminopurine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Famciclov

2003
[Famciclovir plus interferon in the treatment of a patient with chronic hepatitis B and severe liver failure].
    Revista espanola de enfermedades digestivas, 1997, Volume: 89, Issue:3

    Topics: 2-Aminopurine; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Hepatitis B; Hepatitis, Chr

1997
Fatal hepatic decompensation in a patient with hepatitis B cirrhosis following famciclovir withdrawal.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14, Issue:8

    Topics: 2-Aminopurine; Adult; Antiviral Agents; Famciclovir; Fatal Outcome; Hepatitis B; Humans; Liver Cirrh

2000
Efficacy of lamivudine for the treatment of hepatitis B virus infection after liver transplantation in children.
    Transplantation, 2001, Jul-27, Volume: 72, Issue:2

    Topics: 2-Aminopurine; Adolescent; Alanine Transaminase; Antiviral Agents; Child; Child, Preschool; Cystic F

2001