brl 42810 has been researched along with Liver Dysfunction in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Famciclovir, a synthetic acyclic guanine derivative, is a prodrug which, after oral administration, is rapidly metabolised to the highly bioavailable antiviral compound penciclovir." | 2.39 | Famciclovir. A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections. ( Perry, CM; Wagstaff, AJ, 1995) |
| "The pharmacokinetic profile of penciclovir was determined after a single 500-mg dose of its oral precursor, famciclovir, in 9 healthy volunteers and in 14 patients with chronic hepatic disease." | 1.29 | Pharmacokinetics of famciclovir in subjects with chronic hepatic disease. ( Audet, PR; Boike, SC; Fairless, A; Freed, MI; Ilson, BE; Jorkasky, DK; Pue, M; Zariffa, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boike, SC | 1 |
| Pue, M | 1 |
| Audet, PR | 1 |
| Freed, MI | 1 |
| Fairless, A | 1 |
| Ilson, BE | 1 |
| Zariffa, N | 1 |
| Jorkasky, DK | 1 |
| Perry, CM | 1 |
| Wagstaff, AJ | 1 |
| Lau, GK | 1 |
| Lee, CK | 1 |
| Liang, R | 1 |
2 reviews available for brl 42810 and Liver Dysfunction
| Article | Year |
|---|---|
Famciclovir. A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections.
Topics: 2-Aminopurine; Absorption; Administration, Oral; Aging; Antiviral Agents; Controlled Clinical Trials | 1995 |
Hepatitis B virus infection and bone marrow transplantation.
Topics: 2-Aminopurine; Antiviral Agents; Biomarkers; Bone Marrow Transplantation; Famciclovir; Hepatitis B; | 1999 |
1 other study available for brl 42810 and Liver Dysfunction
| Article | Year |
|---|---|
Pharmacokinetics of famciclovir in subjects with chronic hepatic disease.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adolescent; Adult; Biological Availability; Chromato | 1994 |