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brl 42810 and Hepatitis B, Chronic

brl 42810 has been researched along with Hepatitis B, Chronic in 60 studies

Hepatitis B, Chronic: INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.

Research Excerpts

ExcerptRelevanceReference
"Patients with chronic hepatitis B infection and detectable HBV DNA received lamivudine and famciclovir combination therapy."9.11Combination therapy with lamivudine and famciclovir for chronic hepatitis B infection. ( Alsatie, M; Chalasani, N; Eckert, G; Kwo, PY; Lumeng, L; Shen, H, 2004)
"Hepatitis B e antigen-negative/hepatitis B virus (HBV) DNA-positive chronic hepatitis B (CHBe-) exhibits a high relapse rate on monotherapy with lamivudine or interferon-alpha (IFN-alpha)."9.11Sequential combination therapy of HBe antigen-negative/virus-DNA-positive chronic hepatitis B with famciclovir or lamivudine and interferon-alpha-2a. ( Berr, F; Etzrodt, G; Klecker, C; Liebert, UG; Maier, M; Oesen, U; Schiefke, I; Tannapfel, A, 2004)
"We examined whether combination therapy with thymosin-alpha1 and famciclovir would induce hepatitis B e antigen seroconversion in patients with chronic hepatitis B infection in the immune-tolerant phase without inducing significant hepatic necro-inflammation."9.10Thymosin-alpha1 and famciclovir combination therapy activates T-cell response in patients with chronic hepatitis B virus infection in immune-tolerant phase. ( Au, WS; Fong, DY; Hou, J; Kung, HF; Lam, SK; Lau, GK; Lin, M; Nanji, A; Yuen, ST, 2002)
"Lamivudine (LMV) is the only nucleoside analogue approved for the treatment of chronic hepatitis B (CHB)."7.72Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure. ( Ayres, A; Bartholomeusz, A; Lam, KC; Lau, G; Lee, JY; Locarnini, S, 2003)
"To evaluate the clinical efficacy of combined treatment with lamivudine and famciclovir on chronic hepatitis B virus (HBV) infection."7.72[Treatment of patients with chronic hepatitis B virus infect ion with lamivudine combined with famciclovir]. ( Ji, W; Li, L; Su, HB; Wang, HF, 2003)
"We have analyzed the molecular dynamics of emergence of drug-resistant strains in patients receiving lamivudine therapy for chronic hepatitis B."7.70Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. ( Abidi, H; Ahmed, S; Berby, F; Johnson, M; Merle, P; Nafa, S; Pichoud, C; Stuyver, L; Tavan, D; Trépo, C; Zoulim, F, 2000)
"Classic patients with chronic hepatitis B are positive for hepatitis Be-antigen (HBeAg) and HBV-DNA."6.42Thymosin in the treatment of HBeAg-negative chronic hepatitis B. ( Ozden, N; Saruc, M; Yuceyar, H, 2003)
"Patients with chronic hepatitis B infection and detectable HBV DNA received lamivudine and famciclovir combination therapy."5.11Combination therapy with lamivudine and famciclovir for chronic hepatitis B infection. ( Alsatie, M; Chalasani, N; Eckert, G; Kwo, PY; Lumeng, L; Shen, H, 2004)
"Hepatitis B e antigen-negative/hepatitis B virus (HBV) DNA-positive chronic hepatitis B (CHBe-) exhibits a high relapse rate on monotherapy with lamivudine or interferon-alpha (IFN-alpha)."5.11Sequential combination therapy of HBe antigen-negative/virus-DNA-positive chronic hepatitis B with famciclovir or lamivudine and interferon-alpha-2a. ( Berr, F; Etzrodt, G; Klecker, C; Liebert, UG; Maier, M; Oesen, U; Schiefke, I; Tannapfel, A, 2004)
"Twelve patients with a history of childhood malignancy and chronic hepatitis B were treated with prednisone for 4 weeks (0."5.10Serological and molecular response on combined antiviral treatment in children with chronic hepatitis B after pediatric malignancy. ( Benesch, M; Deutsch, J; Dornbusch, HJ; Kerbl, R; Kessler, HH; Lackner, H; Moser, A; Schwinger, W; Sovinz, P; Urban, C, 2002)
"We examined whether combination therapy with thymosin-alpha1 and famciclovir would induce hepatitis B e antigen seroconversion in patients with chronic hepatitis B infection in the immune-tolerant phase without inducing significant hepatic necro-inflammation."5.10Thymosin-alpha1 and famciclovir combination therapy activates T-cell response in patients with chronic hepatitis B virus infection in immune-tolerant phase. ( Au, WS; Fong, DY; Hou, J; Kung, HF; Lam, SK; Lau, GK; Lin, M; Nanji, A; Yuen, ST, 2002)
"There are two licensed drugs for chronic hepatitis B virus (HBV), interferon alfa and lamivudine, with similar efficacy rates."4.81How will we use the new antiviral agents for hepatitis B? ( Perrillo, RP, 2002)
"After several nucleoside analogues have been tested against chronic hepatitis B virus (HBV) infection with minimal success, lamivudine seems to be a highly effective new therapeutic option."4.79Experience with lamivudine against hepatitis B virus. ( Jaeckel, E; Manns, MP, 1997)
"Lamivudine (LMV) is the only nucleoside analogue approved for the treatment of chronic hepatitis B (CHB)."3.72Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure. ( Ayres, A; Bartholomeusz, A; Lam, KC; Lau, G; Lee, JY; Locarnini, S, 2003)
"To evaluate the clinical efficacy of combined treatment with lamivudine and famciclovir on chronic hepatitis B virus (HBV) infection."3.72[Treatment of patients with chronic hepatitis B virus infect ion with lamivudine combined with famciclovir]. ( Ji, W; Li, L; Su, HB; Wang, HF, 2003)
"Therapy of chronic hepatitis B virus (HBV) infection with the polymerase inhibitor lamivudine frequently is associated with the emergence of viral resistance."3.72The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro. ( Arnold, E; Das, K; Delaney, WE; Gibbs, CS; Miller, MD; Westland, CE; Xiong, S; Yang, H, 2003)
"Treatment for chronic hepatitis B with lamivudine is often hampered by the emergence of point mutations in the YMDD motif of the HBV DNA polymerase gene that confer drug resistance."3.72Detection of hepatitis B virus variants resistant to lamivudine and famciclovir among randomly selected chronic carriers from Spain. ( Echevarría, JM; León, P; Pozo, F, 2004)
"Nucleoside analogues such as lamivudine for chronic hepatitis B have an excellent safety profile while patients are on therapy but reactivation flares occur in 19-50% of patients after stopping therapy, some of whom develop liver decompensation."3.71Fatal hepatitis B reactivation following discontinuation of nucleoside analogues for chronic hepatitis B. ( Guan, R; Kajiji, T; Lim, SG; Rajnakova, A; Wai, CT, 2002)
"We have analyzed the molecular dynamics of emergence of drug-resistant strains in patients receiving lamivudine therapy for chronic hepatitis B."3.70Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. ( Abidi, H; Ahmed, S; Berby, F; Johnson, M; Merle, P; Nafa, S; Pichoud, C; Stuyver, L; Tavan, D; Trépo, C; Zoulim, F, 2000)
"Classic patients with chronic hepatitis B are positive for hepatitis Be-antigen (HBeAg) and HBV-DNA."2.42Thymosin in the treatment of HBeAg-negative chronic hepatitis B. ( Ozden, N; Saruc, M; Yuceyar, H, 2003)
"Lamivudine has been demonstrated to have consistent efficacy and safety in large-scale, phase III clinical trials."2.41Nucleoside analogues in the treatment of chronic hepatitis B. ( Leung, N, 2000)
"Due to its low efficacy, 40% in the treatment of chronic hepatitis B and 10-20% in the treatment of chronic hepatitis C, and to its adverse events, in some cases severe, new antiviric molecules are being investigated."2.40[New antiviral agents in the treatment of chronic hepatitis B and C]. ( Córdoba Cortijo, J; López Viedma, B; Olaso Peiró, V, 1998)
"Only one hepatocellular carcinoma developed, which was successfully treated by locoregional ablative therapy."1.33Improved outcome of chronic hepatitis B after heart transplantation by long-term antiviral therapy. ( Bara, C; Böker, KH; Deterding, K; Haverich, A; Manns, MP; Meyer, S; Pethig, K; Potthoff, A; Tillmann, HL; Wedemeyer, H, 2006)
"Lamivudine was effective also after famciclovir breakthrough in 94% of patients."1.31[Therapy of recurrent hepatitis B infection after liver transplantation. A retrospective analysis of 200 liver transplantations based on hepatitis B associated liver diseases]. ( Bechstein, WO; Berg, T; Hopf, U; Langrehr, JM; Müller, AR; Naumann, U; Neuhaus, P; Neuhaus, R; Platz, KP; Rayes, N; Seehofer, D; Steinmüller, T, 2000)
"Lamivudine 3 mg/kg was administered on a compassionate-use basis for 14-36 months."1.31Efficacy of lamivudine for the treatment of hepatitis B virus infection after liver transplantation in children. ( Bar-Nathan, N; Ben-Ari, Z; Dinari, G; Mor, E; Shapira, R; Sokal, EM; Tur-Kaspa, R, 2001)
"Medical therapy of chronic hepatitis B aims at halting progression towards cirrhosis/hepatocellular carcinoma by inhibiting replication of hepatitis B virus in a sustained fashion (viral elimination)."1.30[Drug therapy of chronic hepatitis B]. ( Lavanchy, D; Renner, EL, 1998)
"Prolonged therapy for chronic hepatitis B (HBV) with nucleoside analogs may result in the emergence of HBV mutants resistant to antivirals."1.30Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance. ( Pichoud, C; Seignères, B; Trépo, C; Wang, Z; Zoulim, F, 1999)
"A consensus meeting on the treatment of chronic hepatitis B infection was conducted in Hong Kong, in August 1997."1.30Treatment of chronic hepatitis B virus infection: an Asia-Pacific perspective. ( Carman, WF; Lam, SK; Lau, GK; Locarnini, SA; Lu, ZM; Okuda, K; Williams, R, 1999)
"We described two chronic hepatitis B carriers (both hepatitis B e antigen negative), who cleared HBsAg after allogeneic bone marrow transplantation."1.30Histological changes during clearance of chronic hepatitis B virus infection by adoptive immunity transfer. ( Au, WY; Lau, GK; Liang, R; Wu, PC; Yuen, ST, 1999)
"Lamivudine was well tolerated and liver function improved."1.30Disappearance of hepatitis B virus core deletion mutants and successful combined kidney/liver transplantation in a patient treated with lamivudine. ( Bechstein, WO; Budde, K; Hocher, B; Krüger, DH; Meisel, H; Neuhaus, P; Neumayer, HH; Preikschat, P; Reinke, P, 1999)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (30.00)18.2507
2000's42 (70.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Menne, S1
Asif, G1
Narayanasamy, J1
Butler, SD1
George, AL1
Hurwitz, SJ1
Schinazi, RF1
Chu, CK1
Cote, PJ1
Gerin, JL3
Tennant, BC3
Lai, CL1
Yuen, MF1
Hui, CK1
Garrido-Lestache, S1
Cheng, CT1
Lai, YP1
Demirtürk, N1
Usluer, G1
Ozgünes, I1
Colak, H1
Kartal, ED1
Dinçer, S1
Papatheodoridis, GV1
Dimou, E1
Papadimitropoulos, V1
Lim, SG1
Wai, CT1
Rajnakova, A1
Kajiji, T1
Guan, R1
Wolters, LM3
Hansen, BE1
Niesters, HG3
de Man, RA4
Lackner, H1
Moser, A1
Benesch, M1
Deutsch, J1
Kessler, HH1
Kerbl, R1
Schwinger, W1
Dornbusch, HJ1
Sovinz, P1
Urban, C1
Li, L2
Shao, Q1
Zhang, J1
Ji, D1
Ayres, A1
Bartholomeusz, A1
Lau, G1
Lam, KC1
Lee, JY1
Locarnini, S3
Wang, HF1
Su, HB1
Ji, W1
Saruc, M1
Ozden, N1
Yuceyar, H1
Lagget, M1
Rizzetto, M1
Delaney, WE1
Yang, H1
Westland, CE1
Das, K1
Arnold, E1
Gibbs, CS2
Miller, MD1
Xiong, S1
León, P1
Pozo, F1
Echevarría, JM1
Shen, H1
Alsatie, M1
Eckert, G1
Chalasani, N1
Lumeng, L1
Kwo, PY1
Schiefke, I1
Klecker, C1
Maier, M1
Oesen, U1
Etzrodt, G1
Tannapfel, A1
Liebert, UG1
Berr, F1
Sagir, A1
Avci, A1
Erhardt, A1
Lörke, J1
Heintges, T1
Häussinger, D1
Wang, ZY1
Guo, SH1
Zhang, DF1
Zhao, YR1
Ren, H1
Zhou, XQ1
Xu, DZ1
Sun, JY1
Yao, JL1
Lu, WL1
Potthoff, A1
Tillmann, HL3
Bara, C1
Deterding, K1
Pethig, K2
Meyer, S1
Haverich, A2
Böker, KH3
Manns, MP4
Wedemeyer, H2
Krüger, M1
Trautwein, C1
Bode, U1
Oldhafer, K1
Maschek, H1
Broelsch, CE1
Pichlmayr, R1
McCaughan, G1
Angus, P1
Bowden, S1
Shaw, T2
Breschkin, A1
Sheil, R1
Tassopoulos, NC1
Olaso Peiró, V1
López Viedma, B1
Córdoba Cortijo, J1
Honkoop, P1
Jaeckel, E1
Marques, AR1
Lau, DT1
McKenzie, R1
Straus, SE1
Hoofnagle, JH1
Renner, EL1
Lavanchy, D1
Pichoud, C4
Seignères, B2
Wang, Z1
Trépo, C6
Zoulim, F5
Main, J1
McCarron, B1
Thomas, HC1
Lau, GK5
Carman, WF2
Locarnini, SA1
Okuda, K1
Lu, ZM1
Williams, R1
Lam, SK2
Yuen, ST2
Au, WY1
Wu, PC1
Liang, R1
Meisel, H1
Preikschat, P1
Reinke, P1
Hocher, B1
Budde, K1
Bechstein, WO3
Neuhaus, P3
Krüger, DH1
Neumayer, HH1
Young, CL1
Hultgren, C1
Weiland, O1
Milich, DR1
Sällberg, M1
Petzold, DR1
Flemming, P1
Vollmar, J1
Bastürk, M1
Goldmann, E1
Griffin, KE1
Berby, F2
Stuyver, L2
Petit, MA1
Ahmed, SS1
Hantz, O1
Freiman, JS1
McCaughan, GW1
Korba, BE2
Cote, P2
Hornbuckle, W2
Schinazi, R1
Zavaglia, C1
Airoldi, A1
Pinzello, G1
Hou, J3
Fen, X1
Nie, Z1
Jezek, P1
Atkinson, G1
Boon, R1
Young, C2
Tsiang, M1
Yuen, S1
Zhang, L1
Lam, S1
Marcellin, P1
Habal, F1
Desmond, P1
Wright, T1
Rose, T1
Jurewicz, R1
Leung, N1
Nafa, S1
Ahmed, S1
Tavan, D1
Johnson, M1
Merle, P1
Abidi, H1
Seehofer, D2
Rayes, N2
Naumann, U1
Neuhaus, R2
Berg, T2
Hopf, U1
Langrehr, JM1
Steinmüller, T1
Platz, KP1
Müller, AR2
Suárez García, E1
Romero Gómez, M1
Grande Santamaría, L1
Forns, X1
Sánchez-Tapias, JM1
Fried, MW1
Sommadossi, JP1
Shapira, R1
Mor, E1
Bar-Nathan, N1
Sokal, EM1
Tur-Kaspa, R1
Dinari, G1
Ben-Ari, Z1
Perrillo, RP1
Di Bisceglie, AM1
Nanji, A1
Fong, DY1
Au, WS1
Lin, M1
Kung, HF1

Reviews

17 reviews available for brl 42810 and Hepatitis B, Chronic

ArticleYear
Nucleoside analogues for chronic hepatitis B: antiviral efficacy and viral resistance.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:7

    Topics: 2-Aminopurine; Antiviral Agents; Cross Reactions; Drug Resistance, Viral; Famciclovir; Hepatitis B v

2002
Thymosin in the treatment of HBeAg-negative chronic hepatitis B.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:8

    Topics: 2-Aminopurine; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Hepatitis B e Antigens; Hep

2003
Current pharmacotherapy for the treatment of chronic hepatitis B.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:10

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Clinical Trials as Topic; Famciclovir; Hepatitis B e Antig

2003
[New approaches in the treatment of hepatitis B].
    Deutsche medizinische Wochenschrift (1946), 2004, May-21, Volume: 129, Issue:21

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contrai

2004
Chronic hepatitis B: interferon-monotherapy or combination with nucleoside analogues?
    Liver, 1998, Volume: 18, Issue:2

    Topics: 2-Aminopurine; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Hepatitis B, Chronic; Human

1998
[New antiviral agents in the treatment of chronic hepatitis B and C].
    Revista espanola de enfermedades digestivas, 1998, Volume: 90, Issue:4

    Topics: 2-Aminopurine; Antimetabolites; Antiviral Agents; Clinical Trials as Topic; Famciclovir; Hepatitis B

1998
Experience with lamivudine against hepatitis B virus.
    Intervirology, 1997, Volume: 40, Issue:5-6

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; F

1997
Treatment of chronic viral hepatitis.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:6

    Topics: 2-Aminopurine; Animals; Antimetabolites; Antiviral Agents; Carcinoma, Hepatocellular; Disease Models

1998
New antiviral agents for the therapy of chronic hepatitis B virus infection.
    Intervirology, 1999, Volume: 42, Issue:2-3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Dr

1999
Famciclovir update. Chronic hepatitis B.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: 2-Aminopurine; Antiviral Agents; Clinical Trials, Phase II as Topic; Famciclovir; Hepatitis B, Chron

1999
Current limitations to nucleoside analogue therapy for chronic hepatitis B virus infection in the liver transplant and non-transplant settings.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:3

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; DNA, Viral; Famciclovir; Hepatitis B e Antigens; Hepatitis

2000
Antiviral therapy of HBV- and HCV-induced liver cirrhosis.
    Journal of clinical gastroenterology, 2000, Volume: 30, Issue:3

    Topics: 2-Aminopurine; Antiviral Agents; Clinical Trials as Topic; Famciclovir; Female; Hepatitis B, Chronic

2000
Nucleoside analogues in the treatment of chronic hepatitis B.
    Journal of gastroenterology and hepatology, 2000, Volume: 15 Suppl

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Deoxycytidine; Emtricitabine; Famciclovir; Hepatitis B e A

2000
Nucleoside analogues and other investigational modalities for the treatment of chronic hepatitis B.
    Antiviral therapy, 1996, Volume: 1, Issue:2

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Combined

1996
Hepatitis B infection in China.
    Clinics in liver disease, 2001, Volume: 5, Issue:2

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; China; Deoxycytidine; DNA, Viral; Drug Therapy, Combinatio

2001
Nucleoside analogues for chronic hepatitis B.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:12

    Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepa

2001
How will we use the new antiviral agents for hepatitis B?
    Current gastroenterology reports, 2002, Volume: 4, Issue:1

    Topics: 2-Aminopurine; Adenine; Alanine Transaminase; Antiviral Agents; Drug Resistance; Drug Therapy, Combi

2002

Trials

16 trials available for brl 42810 and Hepatitis B, Chronic

ArticleYear
Comparison of the efficacy of lamivudine and famciclovir in Asian patients with chronic hepatitis B: results of 24 weeks of therapy.
    Journal of medical virology, 2002, Volume: 67, Issue:3

    Topics: 2-Aminopurine; Adolescent; Adult; Antiviral Agents; China; DNA, Viral; Famciclovir; Female; Hepatiti

2002
Comparison of different treatment combinations for chronic hepatitis B infection.
    Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:3

    Topics: 2-Aminopurine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Administration Schedule;

2002
Viral dynamics in chronic hepatitis B patients treated with lamivudine, lamivudine-famciclovir or lamivudine-ganciclovir.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:9

    Topics: 2-Aminopurine; Adult; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Female; Ganciclovir;

2002
Serological and molecular response on combined antiviral treatment in children with chronic hepatitis B after pediatric malignancy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2002, Volume: 25 Suppl 3

    Topics: 2-Aminopurine; Adolescent; Antiviral Agents; Child; Child, Preschool; DNA, Viral; Drug Therapy, Comb

2002
[Famciclovir treatment of patients with chronic hepatitis B virus infection].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2002, Volume: 16, Issue:4

    Topics: 2-Aminopurine; Adolescent; Aged; Antiviral Agents; Famciclovir; Female; Hepatitis B virus; Hepatitis

2002
Combination therapy with lamivudine and famciclovir for chronic hepatitis B infection.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2004, Volume: 2, Issue:4

    Topics: 2-Aminopurine; Adult; Aged; Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Adm

2004
Sequential combination therapy of HBe antigen-negative/virus-DNA-positive chronic hepatitis B with famciclovir or lamivudine and interferon-alpha-2a.
    Liver international : official journal of the International Association for the Study of the Liver, 2004, Volume: 24, Issue:2

    Topics: 2-Aminopurine; Administration, Oral; Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents

2004
[Clinical investigation of famciclovir in chronic hepatitis B patients irresponsive to alpha interferon treatment].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:7

    Topics: 2-Aminopurine; Adolescent; Adult; Antiviral Agents; Double-Blind Method; Famciclovir; Female; Follow

2005
Famciclovir treatment of hepatitis B virus recurrence after liver transplantation: a pilot study.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1996, Volume: 2, Issue:4

    Topics: 2-Aminopurine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Famciclovir; Female;

1996
Combination therapy with famciclovir and interferon-alpha for the treatment of chronic hepatitis B.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:5

    Topics: 2-Aminopurine; Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; DNA, Vira

1998
Famciclovir treatment of chronic hepatitis B in heart transplant recipients: a prospective trial.
    Transplantation, 1999, Nov-27, Volume: 68, Issue:10

    Topics: 2-Aminopurine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combin

1999
Evolution of hepatitis B virus polymerase gene sequence during famciclovir therapy for chronic hepatitis B.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:4

    Topics: 2-Aminopurine; Adult; Amino Acid Sequence; Antiviral Agents; Cloning, Molecular; Drug Resistance, Mi

2000
Famciclovir in chronic hepatitis B: results of a dose-finding study.
    Journal of hepatology, 2000, Volume: 32, Issue:6

    Topics: 2-Aminopurine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Dose-Response Relationship

2000
Combination therapy with lamivudine and famciclovir for chronic hepatitis B-infected Chinese patients: a viral dynamics study.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:2

    Topics: 2-Aminopurine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Famciclov

2000
A randomized, placebo-controlled study to evaluate the efficacy of 12-month famciclovir treatment in patients with chronic hepatitis B e antigen-positive hepatitis B.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:2

    Topics: 2-Aminopurine; Adolescent; Adult; Aged; Alanine Transaminase; DNA, Viral; Double-Blind Method; Famci

2000
Thymosin-alpha1 and famciclovir combination therapy activates T-cell response in patients with chronic hepatitis B virus infection in immune-tolerant phase.
    Journal of viral hepatitis, 2002, Volume: 9, Issue:4

    Topics: 2-Aminopurine; Adjuvants, Immunologic; Adolescent; Adult; Antiviral Agents; Cell Division; Cells, Cu

2002

Other Studies

27 other studies available for brl 42810 and Hepatitis B, Chronic

ArticleYear
Antiviral effect of orally administered (-)-beta-D-2-aminopurine dioxolane in woodchucks with chronic woodchuck hepatitis virus infection.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Administration, Oral; Animals; Antiviral Agents; Dioxolanes; DNA, Viral; Dose-Response Relationship,

2007
Fatal hepatitis B reactivation following discontinuation of nucleoside analogues for chronic hepatitis B.
    Gut, 2002, Volume: 51, Issue:4

    Topics: 2-Aminopurine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Bilirubin; DNA, Viral; Drug Resi

2002
Lamivudine and Famciclovir resistant hepatitis B virus associated with fatal hepatic failure.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 27, Issue:1

    Topics: 2-Aminopurine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Famciclov

2003
[Treatment of patients with chronic hepatitis B virus infect ion with lamivudine combined with famciclovir].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2003, Volume: 17, Issue:2

    Topics: 2-Aminopurine; Adolescent; Adult; Aged; Antiviral Agents; Child; Drug Therapy, Combination; Famciclo

2003
The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro.
    Journal of virology, 2003, Volume: 77, Issue:21

    Topics: 2-Aminopurine; Amino Acid Sequence; Antiviral Agents; Drug Resistance, Viral; Famciclovir; Hepatitis

2003
Detection of hepatitis B virus variants resistant to lamivudine and famciclovir among randomly selected chronic carriers from Spain.
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:3

    Topics: 2-Aminopurine; Amino Acid Sequence; Antiviral Agents; Diagnostic Tests, Routine; DNA Mutational Anal

2004
Improved outcome of chronic hepatitis B after heart transplantation by long-term antiviral therapy.
    Journal of viral hepatitis, 2006, Volume: 13, Issue:11

    Topics: 2-Aminopurine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Famciclovir; Female; Heart

2006
Retransplantation for precore mutant-related chronic hepatitis B infection: prolonged survival in a patient receiving sequential ganciclovir/famciclovir therapy.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1996, Volume: 2, Issue:6

    Topics: 2-Aminopurine; Antiviral Agents; DNA, Viral; Famciclovir; Follow-Up Studies; Ganciclovir; Graft Reje

1996
Efficacy of famciclovir treatment in chronic hepatitis B patients with different mutations at position 552 of the DNA polymerase gene.
    Journal of hepatology, 1998, Volume: 28, Issue:5

    Topics: 2-Aminopurine; Alanine Transaminase; Antiviral Agents; DNA-Directed DNA Polymerase; DNA, Viral; Famc

1998
[Drug therapy of chronic hepatitis B].
    Sozial- und Praventivmedizin, 1998, Volume: 43 Suppl 1

    Topics: 2-Aminopurine; Antiviral Agents; Famciclovir; Hepatitis B virus; Hepatitis B, Chronic; Humans; Inter

1998
Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:1

    Topics: 2-Aminopurine; Adult; Amino Acid Sequence; Antiviral Agents; Biomarkers; Cells, Cultured; Cloning, M

1999
Treatment of chronic hepatitis B virus infection: an Asia-Pacific perspective.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:1

    Topics: 2-Aminopurine; Adjuvants, Immunologic; Animals; Antiviral Agents; Asia; Drug Therapy, Combination; F

1999
Histological changes during clearance of chronic hepatitis B virus infection by adoptive immunity transfer.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:3

    Topics: 2-Aminopurine; Adolescent; Adult; Antiviral Agents; Bone Marrow Transplantation; Famciclovir; Hepati

1999
Disappearance of hepatitis B virus core deletion mutants and successful combined kidney/liver transplantation in a patient treated with lamivudine.
    Transplant international : official journal of the European Society for Organ Transplantation, 1999, Volume: 12, Issue:4

    Topics: 2-Aminopurine; Antiviral Agents; DNA, Viral; Famciclovir; Follow-Up Studies; Genetic Variation; Hepa

1999
Cell-mediated immune responses and loss of hepatitis B e-antigen (HBeAg) during successful lamivudine and famciclovir combination therapy for chronic replicating hepatitis B virus infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:6

    Topics: 2-Aminopurine; Aged; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Famciclovir; Hepatitis

1999
Persistence of viral replication after anti-HBe seroconversion during antiviral therapy for chronic hepatitis B.
    Journal of hepatology, 2000, Volume: 32, Issue:2

    Topics: 2-Aminopurine; Antibodies, Viral; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Tri

2000
Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks.
    Antiviral research, 2000, Volume: 45, Issue:1

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Carrier State; Disease Models, Animal; Drug Therapy, Combi

2000
Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:5

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Famciclovir; Hepatitis B Virus, Woodchuck; Hepatitis B, Ch

2000
[Dynamic changes of hepatitis B virus during treatment with lamivudine versus lamivudine plus famciclovir].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2000, Volume: 8, Issue:2

    Topics: 2-Aminopurine; Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Female;

2000
Combination chemotherapy for hepatitis B virus: the final solution?
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:2

    Topics: 2-Aminopurine; Antiviral Agents; DNA, Viral; Drug Resistance; Drug Therapy, Combination; Famciclovir

2000
Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:5

    Topics: 2-Aminopurine; Adolescent; Adult; Aged; Aged, 80 and over; DNA, Viral; Drug Resistance, Microbial; D

2000
[Therapy of recurrent hepatitis B infection after liver transplantation. A retrospective analysis of 200 liver transplantations based on hepatitis B associated liver diseases].
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:9

    Topics: 2-Aminopurine; Adult; Antiviral Agents; Dose-Response Relationship, Drug; Drug Administration Schedu

2000
Antiviral combination therapy for lamivudine-resistant hepatitis B reinfection after liver transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2000, Volume: 13 Suppl 1

    Topics: 2-Aminopurine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Microbial; Drug

2000
[Current treatment of hepatitis B].
    Gastroenterologia y hepatologia, 2001, Volume: 24 Suppl 1

    Topics: 2-Aminopurine; Adenine; Anti-Inflammatory Agents; Antiviral Agents; DNA Replication; Famciclovir; Fo

2001
[Laboratory diagnosis of hepatitis B].
    Gastroenterologia y hepatologia, 2001, Volume: 24 Suppl 1

    Topics: 2-Aminopurine; Acute Disease; Antiviral Agents; DNA Replication; DNA, Viral; Drug Resistance; Famcic

2001
Efficacy of lamivudine for the treatment of hepatitis B virus infection after liver transplantation in children.
    Transplantation, 2001, Jul-27, Volume: 72, Issue:2

    Topics: 2-Aminopurine; Adolescent; Alanine Transaminase; Antiviral Agents; Child; Child, Preschool; Cystic F

2001
Combination therapy for hepatitis B.
    Gut, 2002, Volume: 50, Issue:4

    Topics: 2-Aminopurine; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Forecasting; Hepatitis B, C

2002