Page last updated: 2024-10-26
brl 42810 and Ache
brl 42810 has been researched along with Ache in 17 studies
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the safety and efficacy of famciclovir compared to acyclovir in patients with herpes zoster, to determine whether the two regimens are equally effective for the treatment of patients with uncomplicated herpes zoster over a period of 7days." | 9.27 | Randomized clinical trial of famciclovir or acyclovir for the treatment of herpes zoster in adults. ( Amazonas, RB; de Oliveira, MFB; Gambero, S; Pott Junior, H, 2018) |
| "In this randomized, double-blind, multicenter, acyclovir-controlled study, the efficacy and safety of famciclovir were evaluated for the treatment of herpes zoster in patients who were immunocompromised following bone marrow or solid organ transplantation or oncology treatment." | 9.09 | A randomized, double-blind trial of famciclovir versus acyclovir for the treatment of localized dermatomal herpes zoster in immunocompromised patients. ( Belanger, R; Bezwoda, W; Boon, R; Ljungman, P; Saltzman, RL; Tyring, S, 2001) |
| "This study investigated the safety and efficacy of famciclovir compared to acyclovir in patients with herpes zoster, to determine whether the two regimens are equally effective for the treatment of patients with uncomplicated herpes zoster over a period of 7days." | 5.27 | Randomized clinical trial of famciclovir or acyclovir for the treatment of herpes zoster in adults. ( Amazonas, RB; de Oliveira, MFB; Gambero, S; Pott Junior, H, 2018) |
| "In this randomized, double-blind, multicenter, acyclovir-controlled study, the efficacy and safety of famciclovir were evaluated for the treatment of herpes zoster in patients who were immunocompromised following bone marrow or solid organ transplantation or oncology treatment." | 5.09 | A randomized, double-blind trial of famciclovir versus acyclovir for the treatment of localized dermatomal herpes zoster in immunocompromised patients. ( Belanger, R; Bezwoda, W; Boon, R; Ljungman, P; Saltzman, RL; Tyring, S, 2001) |
| "Famciclovir, the well absorbed oral pro-drug of penciclovir, is effective in the treatment of herpes zoster when given three times daily." | 2.71 | Once, twice, or three times daily famciclovir compared with aciclovir for the oral treatment of herpes zoster in immunocompetent adults: a randomized, multicenter, double-blind clinical trial. ( Ashton, R; Candaele, D; Decroix, J; Forszpaniak, C; Paulet, C; Shafran, SD; Tyring, SK; Wade, A, 2004) |
| "In addition, they demonstrated that treatment of acute herpes zoster patients with famciclovir significantly reduces both the duration and prevalence of PHN." | 2.69 | Postherpetic neuralgia: impact of famciclovir, age, rash severity, and acute pain in herpes zoster patients. ( Boon, RJ; Dworkin, RH; Griffin, DR; Phung, D, 1998) |
| "Reactivation of varicella zoster virus (VZV) is a common event in patients undergoing allogeneic bone marrow transplantation (BMT) and may lead to life-threatening complications." | 2.69 | Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. ( Akhtar, M; DesJardin, J; Griffith, J; Koc, Y; Miller, KB; Schenkein, DP; Snydman, DR, 2000) |
| "Zoster-associated pain has a complex pathophysiology that begins with viral damage and increased sensitization of peripheral sensory neurons." | 2.41 | Understanding pain in herpes zoster: an essential for optimizing treatment. ( Wood, M, 2002) |
| "Persistent pain is the most debilitating sequela and it occurs in at least 15% of individuals over 50 years of age." | 2.40 | Therapeutic approaches to the management of herpes zoster. ( Gnann, JW; Whitley, RJ, 1999) |
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Tsunoda, K | 1 |
| Endo, R | 1 |
| Pott Junior, H | 1 |
| de Oliveira, MFB | 1 |
| Gambero, S | 1 |
| Amazonas, RB | 1 |
| Imafuku, S | 1 |
| Nakayama, J | 1 |
| Higa, K | 1 |
| Furue, M | 1 |
| Takahara, M | 1 |
| Katayama, I | 1 |
| Tani, M | 1 |
| Wood, M | 1 |
| Jubelt, B | 1 |
| Shafran, SD | 1 |
| Tyring, SK | 1 |
| Ashton, R | 1 |
| Decroix, J | 1 |
| Forszpaniak, C | 1 |
| Wade, A | 1 |
| Paulet, C | 1 |
| Candaele, D | 1 |
| Wassilew, S | 1 |
| Wassilew, SW | 1 |
| Boon, RJ | 3 |
| Griffin, DR | 3 |
| Pereles, L | 1 |
| Triscott, J | 1 |
| Meiring, P | 1 |
| Dworkin, RH | 2 |
| Phung, D | 1 |
| Spruance, SL | 1 |
| Rowe, NH | 1 |
| Raborn, GW | 1 |
| Thibodeau, EA | 1 |
| D'Ambrosio, JA | 1 |
| Bernstein, DI | 1 |
| Whitley, RJ | 1 |
| Gnann, JW | 1 |
| Koc, Y | 1 |
| Miller, KB | 1 |
| Schenkein, DP | 1 |
| Griffith, J | 1 |
| Akhtar, M | 1 |
| DesJardin, J | 1 |
| Snydman, DR | 1 |
| Tyring, S | 1 |
| Belanger, R | 1 |
| Bezwoda, W | 1 |
| Ljungman, P | 1 |
| Boon, R | 1 |
| Saltzman, RL | 1 |
| Nagasako, EM | 1 |
| Johnson, RW | 1 |
| Griffin, DRJ | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Multicenter Study of the Efficacy and Safety of Famciclovir 500 mg Comparing To Aciclovir 400mg in Patients With Herpes Zoster[NCT01327144] | Phase 3 | 177 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| A Randomized, Efficacy Assessor-Blinded, Study to Assess Preliminary Efficacy and Safety of EDTA Eye Drops v. an Active Comparator in the Suppression of Herpes Simplex Virus Eruptions in Subjects With a History of Herpes Labialis[NCT04893577] | Phase 2 | 20 participants (Anticipated) | Interventional | 2022-01-20 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
6 reviews available for brl 42810 and Ache
| Article | Year |
|---|---|
Understanding pain in herpes zoster: an essential for optimizing treatment.
Topics: 2-Aminopurine; Acyclovir; Analgesics; Antiviral Agents; Chronic Disease; Clinical Trials as Topic; F | 2002 |
[Varicella-zoster virus infections--2: Zoster pain -- therapy and prevention].
Topics: 2-Aminopurine; Acute Disease; Acyclovir; Administration, Oral; Adult; Age Factors; Analgesics, Non-N | 2006 |
Efficacy of famciclovir in the treatment of herpes zoster: reduction of pain associated with zoster.
Topics: 2-Aminopurine; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Pain; Pain Measurement | 1995 |
Famciclovir: efficacy in zoster and issues in the assessment of pain.
Topics: 2-Aminopurine; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Pain; Pain Measurement | 1996 |
Therapeutic approaches to the management of herpes zoster.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Herpes Zoster; Humans; Pain; Prednisone; Pr | 1999 |
Acute pain in herpes zoster: the famciclovir database project.
Topics: 2-Aminopurine; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Age | 2001 |
Trials
8 trials available for brl 42810 and Ache
| Article | Year |
|---|---|
Randomized clinical trial of famciclovir or acyclovir for the treatment of herpes zoster in adults.
Topics: 2-Aminopurine; Acyclovir; Adult; Aged; Antiviral Agents; Famciclovir; Female; Herpes Zoster; Herpesv | 2018 |
Valacyclovir and famciclovir therapy in herpes zoster.
Topics: 2-Aminopurine; Acyclovir; Aged; Antiviral Agents; Double-Blind Method; Famciclovir; Gastrointestinal | 2002 |
Once, twice, or three times daily famciclovir compared with aciclovir for the oral treatment of herpes zoster in immunocompetent adults: a randomized, multicenter, double-blind clinical trial.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Double-Bl | 2004 |
Brivudin compared with famciclovir in the treatment of herpes zoster: effects in acute disease and chronic pain in immunocompetent patients. A randomized, double-blind, multinational study.
Topics: 2-Aminopurine; Acute Disease; Administration, Oral; Aged; Antiviral Agents; Bromodeoxyuridine; Chron | 2005 |
Postherpetic neuralgia: impact of famciclovir, age, rash severity, and acute pain in herpes zoster patients.
Topics: 2-Aminopurine; Acute Disease; Age Factors; Antiviral Agents; Double-Blind Method; Exanthema; Famcicl | 1998 |
Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: A double-blind, dose-ranging, placebo-controlled, multicenter trial.
Topics: 2-Aminopurine; Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Double-Blind Method; | 1999 |
Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome.
Topics: 2-Aminopurine; Acyclovir; Adolescent; Adult; Antiviral Agents; Bone Marrow Transplantation; Chickenp | 2000 |
A randomized, double-blind trial of famciclovir versus acyclovir for the treatment of localized dermatomal herpes zoster in immunocompromised patients.
Topics: 2-Aminopurine; Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Double-Blind Method; Famciclovi | 2001 |
Other Studies
3 other studies available for brl 42810 and Ache
| Article | Year |
|---|---|
Intranasal pain in a patient with Behçet's disease.
Topics: Antiviral Agents; Behcet Syndrome; Blister; Endoscopy; Famciclovir; Female; Glucocorticoids; Herpes | 2020 |
One-year follow-up of zoster-associated pain in 764 immunocompetent patients with acute herpes zoster treated with famciclovir (FAMILIAR study).
Topics: 2-Aminopurine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Cohort Studies; | 2014 |
Dilemmas in care of the elderly.
Topics: 2-Aminopurine; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Costs and Cost Analysis; Famc | 1997 |