brinzolamide has been researched along with Intraocular Pressure in 141 studies
*Intraocular Pressure: The pressure of the fluids in the eye. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (3.55) | 18.2507 |
| 2000's | 57 (40.43) | 29.6817 |
| 2010's | 62 (43.97) | 24.3611 |
| 2020's | 17 (12.06) | 2.80 |
| Authors | Studies |
|---|---|
| Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT | 2 |
| Chen, HH; Dean, T; Gross, S; Liao, J; May, JA; McLaughlin, M; Sly, WS | 1 |
| Casini, A; Menabuoni, L; Mincione, F; Scozzafava, A; Starnotti, M; Supuran, CT | 2 |
| Casini, A; Mincione, F; Montero, JL; Scozzafava, A; Starnotti, M; Supuran, CT; Winum, JY | 1 |
| Bacciottini, L; Casini, A; Masini, E; Mincione, F; Scozzafava, A; Scrivanti, C; Starnotti, M; Supuran, CT; Vullo, D | 1 |
| Cobbs, M; Dinh, DM; Edwards, MP; Gukasyan, HJ; Huang, Q; Lafontaine, JA; Mehta, S; Patterson, BD; Rewolinski, DA; Richardson, PF; Rui, EY | 1 |
| Abdel-Aziz, HA; Bua, S; Eldehna, WM; Fares, M; Keller, PA; Lanzi, C; Lucarini, L; Masini, E; Nocentini, A; Peat, TS; Supuran, CT | 1 |
| Chen, G; Chen, P; Li, J; Peng, X; Wang, J | 1 |
| Aapola, U; Nukareddy, P; Uusitalo, H; Välimäki, J | 1 |
| Inoue, K; Ishida, K; Kunimatsu-Sanuki, S; Tomita, G | 1 |
| Bleskina, MY; Kolotilina, NE; Lisitsyn, AB; Loskutov, IA; Poromov, AA | 1 |
| Adachi, M; Aihara, M; Asato, R; Hamada, N; Hara, T; Mizoue, S; Muramatsu, T; Naito, T; Ohkubo, S; Sakata, R; Yoshikawa, K | 1 |
| Kiyota, N; Kunikane, E; Nakazawa, T; Sato, K; Takahashi, N; Yamazaki, M | 1 |
| Bell, K; Denis, P; Goldberg, I; Hubatsch, D; Lerner, SF; Nicolela, M; Ridolfi, A; Tatham, AJ; Topouzis, F | 1 |
| Holló, G; Kóthy, P | 2 |
| Dangi, JS; Dubey, V; Kesavan, K; Mohan, P | 1 |
| Chen, O; Jamieson, MPH; Ling, D; Perera, N; Pinnuck, BC; Williams, M | 1 |
| Bhalerao, H; Chandran, S; Koteshwara, KB | 2 |
| Chen, J; Gao, X; Li, T; Pan, S; Su, Y; Wang, Y; Zhou, X | 1 |
| Anyfantaki, D; Dettoraki, M; Fragkos, D; Gkounta, A; Legaki, A; Rapti, E; Riga, F; Theiopoulos, I | 1 |
| Adachi, M; Aihara, M; Fukuchi, T; Matsuo, H; Sasaki, N; Togano, T | 1 |
| Akyol, N; Imamoglu, HI; Kalkisim, A; Kola, M; Turk, A | 1 |
| Balsak, S; Erdem, S; Fuat Alakus, M; Kaydu, A; Ozkurt, ZG | 1 |
| Holopainen, JM; Pisella, PJ; Rantamäki, AH; Robciuc, A; Ruokonen, SK; Wiedmer, SK; Witos, J | 1 |
| Pojda-Wilczek, D; Wycisło-Gawron, P | 1 |
| Ma, F; Ma, H; Ma, J; Shang, Q; Su, J; Wang, X; Yu, J; Zhang, T | 1 |
| Jin, SW; Lee, SM | 1 |
| Sun, J; Zhou, Z | 1 |
| Georgakopoulos, CD; Makri, OE; Plotas, P; Tsapardoni, FN | 1 |
| Huang, L; Jiang, C; Jin, Q; Jin, Z; Li, H; Liu, Y; Oswald, J; Song, X; Wang, F; Wu, J; Zhou, Y | 1 |
| Bacharach, J; Burmaster, S; Fechtner, RD; Hubatsch, DA; Kahook, MY; Meng, X; Weinreb, RN; Wirta, D | 1 |
| Georgakopoulos, CD; Kagkelaris, K; Makri, OE; Pagoulatos, D; Plotas, P | 1 |
| Hayashi, K; Manabe, SI; Sato, T; Yoshida, M | 1 |
| Boevé, MH; de Gee, R; Djajadiningrat-Laanen, SC; Elders, DJ; Koele, LE; Slenter, IJM; Vermeer, LW | 1 |
| Jin, SW; Joh, HJ | 1 |
| Eisenberg, D | 1 |
| Goode, SM; McMenemy, MG; Nguyen, QH; Realini, T; Whitson, JT | 1 |
| Eichhorn, M | 1 |
| Chung, IY; Han, YS; Kim, GN; Park, JM; Seo, SW; Yoo, JM | 1 |
| Dubiner, H; Katz, G; Sall, K; Samples, J; Vold, S | 1 |
| Albis-Donado, O; Bello-López-Portillo, H; Gil-Carrasco, F; Sánchez-Noguera, C; Soto-Ortiz, K; Turati-Acosta, M | 1 |
| DuBiner, H; Katz, G; Nguyen, QH; Realini, T | 1 |
| Li, J; Wang, B; Wang, Z; Wu, L; Wu, W; Xin, H; Xu, Q | 1 |
| Chen, T; He, G; He, Z; Lei, Y; Li, H; Ren, K; Song, X; Xia, S; Xie, Y; Zhang, Y; Zheng, Y | 1 |
| Scozzafava, A; Supuran, CT | 1 |
| Akçali, G; Bozkurt, KT; Güney, E; Sezgin Akçay, Bİ; Unlü, C | 1 |
| Hirvonen, J; Ilkka, J; Järvinen, K; Kalesnykas, G; Laaksonen, T; Laru, J; Liu, P; Oksala, O; Peltonen, L; Puranen, J; Rönkkö, S; Tuomela, A | 1 |
| Marques, A | 1 |
| Aung, T; Branch, JD; Goldberg, I; Hernandez Paredes, TJ; Laganovska, G; Tsorbatzoglou, A | 1 |
| Alezzandrini, A; Alfaro, R; Hubatsch, D | 1 |
| Chew, SK; Goldberg, I; Skalicky, SE | 1 |
| Gandolfi, SA; Hamacher, T; Lim, J; Parra Restrepo, JC; Sanseau, AC | 1 |
| Deeks, ED; Greig, SL | 1 |
| Alagoz, G; Altun, G; Celik, E; Turkoglu, EB | 1 |
| Chang, RT; Choi, DY; Friedman, NJ; Yegnashankaran, K | 1 |
| Mansouri, K; Medeiros, FA; Weinreb, RN | 1 |
| Busse, C; Newton, JR; Stavinohova, R | 1 |
| Feldman, RM; Hubatsch, DA; Katz, G; McMenemy, M; Realini, T | 1 |
| Elsaied, HM; Fouad, PH; Galose, MS; Macky, TA | 1 |
| Fukuda, M; Sasaki, H; Shibata, N; Shibata, S; Shibata, T; Sugiyama, K; Takeda, N | 1 |
| Budenz, DL; DuBiner, HB; Fechtner, RD; Hubatsch, DA; Myers, JS | 1 |
| Inoue, R; Kimura, T; Nakano, T; Suzumura, H; Tanino, T; Tatemichi, M; Yamazaki, Y; Yoshikawa, K | 1 |
| Konstantinidis, A; Kozobolis, V; Labiris, G; Panos, GD | 1 |
| Dai, H; Song, S; Yu, XB | 1 |
| DeWitt, PE; Kahook, MY; Kroehl, ME; Seibold, LK | 1 |
| Abdel Hady, M; Ghorab, M; Mahmoud, AA; Salama, HA | 1 |
| Fagan, X; Harper, CA; Ong, D | 1 |
| Arzeno, G; Bergamini, MV; Dickerson, JE; Hua, SY; James, JE; Kaback, M; Landry, TA; Salem, C; Scoper, SV | 1 |
| Cakmak, H; Dayanir, V; Kir, E | 1 |
| Evans, RM; Mallick, S; Stewart, RH; Vold, SD; Walters, T | 1 |
| Liu, JH; Medeiros, FA; Slight, JR; Weinreb, RN | 1 |
| Martínez, A; Sánchez-Salorio, M | 2 |
| Cai, JP; Cheng, JW; Wei, RL | 1 |
| Cheng, JW; Li, Y; Wei, RL | 1 |
| Croxtall, JD; Scott, LJ | 1 |
| Bournias, TE; Lai, J | 1 |
| Bonanno, JA; Cheng, Q; Liu, C; Nguyen, T | 1 |
| Januleviciene, I | 1 |
| Crowston, JG; Goldberg, I; Jasek, MC; Stewart, JA; Stewart, WC | 1 |
| Kim, JH; Lee, DE; Lee, JH; Park, CK; Park, HY | 1 |
| Pfeiffer, N | 1 |
| García Sánchez, J; García-Feijoó, J; Herrero-Vanrell, R; Martínez-de-la-Casa, JM; Sáenz-Francés, F; Sánchez-Pulgarín, M; Santos-Bueso, E | 1 |
| Li Yim, JF; Montgomery, DM | 1 |
| Liu, JH; Realini, T; Weinreb, RN | 1 |
| Bianchi, PE; Bordin, M; Pasinetti, GM; Rossi, GC; Sandolo, F | 1 |
| Kobayashi, H | 1 |
| Cheng, JW; Cheng, SW; Lu, GC; Wei, RL; Yu, DY | 1 |
| Călugăru, D; Călugăru, M | 2 |
| Cojocaru, I; Pop, A; Stefan, C | 1 |
| Chen, DF; Chen, H; Cho, KS; Guo, W; Luo, G; Pang, IH; Wang, WH; Yang, Q; Yu, D | 1 |
| Klemm, M; Matthiessen, ET; Reuss, J; Richard, G; Zeitz, O | 1 |
| Cvetkovic, RS; Perry, CM | 1 |
| McLaughlin, MA; Toris, CB; Zhan, GL | 1 |
| Gray, HE; Morgan, RV; Willis, AM | 1 |
| Arend, O; Kaup, M; Niegel, M; Plange, N; Remky, A | 1 |
| Chen, YF; Huang, JY; Hung, PT; Shieh, JW; Wang, TH | 1 |
| Ermis, SS; Inan, UU; Ozturk, F | 1 |
| Akman, A; Akova, YA; Cetinkaya, A | 1 |
| Castillo, A; Fernandez-Vidal, A; Garcia-Feijoo, J; Garcia-Sanchez, J; Martinez-de-la-Casa, JM; Mendez-Hernandez, C | 1 |
| Aktunç, T; Dayanir, V; Kir, E; Ozcura, F; Ozkan, SB; Topaloğlu, A | 1 |
| Ikeda, H; Matsuyama, S; Mishima, HK; Noma, H; Tsukamoto, H | 1 |
| Ishikawa, H; Kawai, H; Morita, T; Nemoto, T; Nishimoto, H; Ogata, H; Shimizu, K; Shoji, N; Suyama, H; Suzuki, H | 1 |
| Ikeda, H; Mishima, HK; Mukai, S; Noma, H; Tsukamoto, H | 1 |
| Menon, GJ; Vernon, SA | 1 |
| Avila, MP; Magacho, L; Queiroz, CF; Reis, R; Santos, LC | 1 |
| Cerovski, B; Jukić, T; Popović Suić, S; Vukojević, N | 1 |
| Macarie, S; Palko, Z | 1 |
| Akar, Y; Unal, M; Yücel, I | 1 |
| Franks, W | 1 |
| Fang, M; Ge, J; Huang, S; Minbin, Y | 1 |
| Kiuchi, T; Motoyama, Y; Oshika, T | 1 |
| Baker, L; Chuang, AZ; Feldman, RM; Gross, RL; Prager, TC; Reynolds, A; Tanna, AP | 1 |
| Akman, A; Akova, YA; Borazan, M; Karalezli, A | 1 |
| Bojić, L; Capkun, V; Ivanisević, M; Kovacić, Z; Rogosića, V; Stanić, R | 1 |
| Bergamini, MV; Dickerson, JE; Gross, RD; Hua, SY; Landry, TA; Roarty, JD; Robin, AL; Scheib, SA; Scott, H; Vijaya, L; Whitson, JT; Woodside, AM | 1 |
| Sowka, J | 1 |
| Iester, M | 1 |
| Cantor, LB; Harris, A; Kagemann, L; Marques, C; McCranor, L; Siesky, B; Stefansson, E; Weitzman, Y; Werne, A | 1 |
| Day, DG; Hollander, DA | 1 |
| Burger, D; Germann, SE; Matheis, FL; Rampazzo, A; Roos, M; Spiess, BM | 1 |
| Silver, LH | 3 |
| Brubaker, RF; Ingram, CJ | 1 |
| DeSantis, L | 1 |
| Barnes, GE; Chandler, ML; Dean, T; Li, B | 1 |
| Sall, K | 1 |
| Shin, D | 1 |
| March, WF; Ochsner, KI | 1 |
| Brubaker, RF; Ingram, CJ; Nau, CB; Schoff, EO | 1 |
| Barnebey, H; Kwok, SY | 1 |
| Herkel, U; Pfeiffer, N | 2 |
| Friren, B; Michaud, JE | 1 |
15 review(s) available for brinzolamide and Intraocular Pressure
| Article | Year |
|---|---|
[Mode of action, clinical profile and relevance of carbonic anhydrase inhibitors in glaucoma therapy].
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Ciliary Body; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes | 2013 |
Glaucoma and the applications of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Carbonic Anhydrases; Glaucoma; Humans; Intraocular Pressure; Nitric Oxide; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines | 2014 |
Brinzolamide plus brimonidine for the treatment of glaucoma: an update.
Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Quinoxalines; Sulfonamides; Thiazines | 2014 |
Brinzolamide/brimonidine: a review of its use in patients with open-angle glaucoma or ocular hypertension.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazines | 2015 |
Meta-analysis of medical intervention for normal tension glaucoma.
Topics: Aged; Amides; Antihypertensive Agents; Betaxolol; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Travoprost | 2009 |
Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Databases, Factual; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Nerve Diseases; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol | 2009 |
Brinzolamide 1%/timolol 0.5%: safety and efficacy of a new fixed-combination IOP-lowering product for glaucoma.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiazines; Timolol; Treatment Outcome | 2010 |
Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy.
Topics: Adrenergic alpha-2 Receptor Agonists; Carbonic Anhydrase Inhibitors; Databases, Factual; Female; Humans; Intraocular Pressure; Male; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes | 2012 |
[Azarga, a new and useful fixed combination in glaucoma treatment].
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome; Vision, Ocular | 2011 |
[The latest developments in glaucoma therapy using fixed combination products].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate, Timolol Maleate Drug Combination; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2011 |
[Fixed combination of topical prostaglandin analogue in glaucoma treatment].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Optic Nerve; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Timolol; Travoprost; Treatment Outcome; Visual Fields | 2011 |
Brinzolamide : a review of its use in the management of primary open-angle glaucoma and ocular hypertension.
Topics: Carbonic Anhydrase Inhibitors; Costs and Cost Analysis; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines | 2003 |
Brinzolamide.
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Regional Blood Flow; Retinal Vessels; Sulfonamides; Thiazines; Treatment Outcome | 2008 |
Preclinical overview of brinzolamide.
Topics: Absorption; Animals; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Evaluation, Preclinical; Eye; Half-Life; Humans; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiazines; Tissue Distribution | 2000 |
Update on topical carbonic anhydrase inhibitors.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Eye; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes | 2001 |
69 trial(s) available for brinzolamide and Intraocular Pressure
| Article | Year |
|---|---|
Efficacy of brinzolamide in the initial management of acute primary angle closure: A randomized controlled trial.
Topics: Acute Disease; Humans; Intraocular Pressure; Laser Therapy; Sulfonamides; Thiazines | 2022 |
Brinzolamide/brimonidine fixed-dose combination bid as an adjunct to a prostaglandin analog for open-angle glaucoma/ocular hypertension.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiazines; Tonometry, Ocular; Travoprost | 2021 |
Prophylactic effect of brinzolamide-brimonidine fixed combination on intraocular pressure spikes after intravitreal anti-VEGF injections.
Topics: Brimonidine Tartrate; Humans; Intraocular Pressure; Intravitreal Injections; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines | 2021 |
Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Follow-Up Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Evaluation of the effects on choroidal thickness of bimatoprost 0.03% versus a brinzolamide 1.0%/timolol maleate 0.5% fixed combination.
Topics: Adult; Aged; Antihypertensive Agents; Bimatoprost; Choroid; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Single-Blind Method; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence | 2017 |
Brimonidine-timolol versus brinzolamide-timolol for treatment of elevated intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2018 |
24-Hour Intraocular Pressure Control with Fixed-dose Combination Brinzolamide 1%/Brimonidine 0.2%: A Multicenter, Randomized Trial.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines | 2019 |
Brinzolamide-brimonidine fixed combination for the prevention of intraocular pressure elevation after phacoemulsification.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Tonometry, Ocular | 2020 |
Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract; Cataract Extraction; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2019 |
The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
Topics: Animals; Cats; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Sulfonamides; Thiazines; Thiophenes; Timolol | 2020 |
Phase 3 randomized 3-month trial with an ongoing 3-month safety extension of fixed-combination brinzolamide 1%/brimonidine 0.2%.
Topics: Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiazines; Time Factors; Treatment Outcome | 2013 |
Three-month randomized trial of fixed-combination brinzolamide, 1%, and brimonidine, 0.2%.
Topics: Academic Medical Centers; Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Diagnostic Techniques, Ophthalmological; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Least-Squares Analysis; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Predictive Value of Tests; Private Practice; Quinoxalines; Sulfonamides; Thiazines; Time Factors; Treatment Outcome; United States | 2013 |
Fixed-combination brinzolamide 1%/brimonidine 0.2% vs monotherapy with brinzolamide or brimonidine in patients with open-angle glaucoma or ocular hypertension: results of a pooled analysis of two phase 3 studies.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiazines; Visual Acuity | 2013 |
The safety and efficacy of brinzolamide 1%/timolol 0.5% fixed combination versus dorzolamide 2%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Preference; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2013 |
Twice-daily brinzolamide/brimonidine fixed combination versus brinzolamide or brimonidine in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiazines | 2014 |
Efficacy and tolerability of fixed-combination brinzolamide/timolol in Latin American patients with open-angle glaucoma or ocular hypertension previously on brimonidine/timolol fixed combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latin America; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Research Design; Sulfonamides; Thiazines; Timolol; United States | 2014 |
Randomized trial of brinzolamide/brimonidine versus brinzolamide plus brimonidine for open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiazines; Tonometry, Ocular; Treatment Outcome | 2014 |
Short-term effect of topical brinzolamide 1%-timolol 0.5% fixed combination on human central corneal thickness.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Capsule Opacification; Carbonic Anhydrase Inhibitors; Clonidine; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2015 |
Effect of glaucoma medications on 24-hour intraocular pressure-related patterns using a contact lens sensor.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Contact Lenses; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Monitoring, Ambulatory; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Young Adult | 2015 |
A Randomized Trial of Fixed-Dose Combination Brinzolamide 1%/Brimonidine 0.2% as Adjunctive Therapy to Travoprost 0.004.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Tonometry, Ocular; Travoprost; Treatment Outcome | 2016 |
Brinzolamide/timolol versus dorzolamide/timolol fixed combinations: A hospital-based, prospective, randomized study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Egypt; Female; Glaucoma, Open-Angle; Hospitals, University; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
Ocular hypotensive effect of fixed-combination brinzolamide/brimonidine adjunctive to a prostaglandin analog: a randomized clinical trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Tonometry, Ocular; Travoprost; Visual Acuity | 2016 |
Effects of Brinzolamide, a Topical Carbonic Anhydrase Inhibitor, on Corneal Endothelial Cells.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cornea; Drug Therapy, Combination; Endothelial Cells; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Tonometry, Ocular | 2016 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Effect of prophylactic intraocular pressure-lowering medication (brinzolamide) on intraocular pressure after ranibizumab intravitreal injection: A case-control study.
Topics: Angiogenesis Inhibitors; Carbonic Anhydrase Inhibitors; Case-Control Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Tonometry, Ocular; Treatment Outcome | 2016 |
The 24-Hour Effects of Brinzolamide/Brimonidine Fixed Combination and Timolol on Intraocular Pressure and Ocular Perfusion Pressure.
Topics: Aged; Blood Pressure; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2017 |
Intraocular pressure-lowering efficacy of brinzolamide 1%/timolol 0.5% fixed combination compared with brinzolamide 1% and timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Visual Acuity | 2008 |
Medical control of intraocular pressure with brinzolamide 1% after phacoemulsification.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Tonometry, Ocular; Treatment Outcome | 2008 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
Comparing diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure in patients receiving latanoprost monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2009 |
A comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2009 |
Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Single-Blind Method; Sulfonamides; Thiazines; Thiophenes; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Predictors for visual field progression and the effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Disease Progression; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Proportional Hazards Models; Prospective Studies; Retinal Artery; Risk Factors; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler, Color; Vision Disorders; Visual Fields | 2010 |
Intraocular pressure-lowering efficacy of brinzolamide when added to travoprost/timolol fixed combination as adjunctive therapy.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Visual Acuity | 2012 |
Timolol versus brinzolamide added to travoprost in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2011 |
[Comparative study of the pressure lowering efficacy and variations in the ocular pulse amplitude between fixed combinations of dorzolamide/timolol and brinzolamide/timolol].
Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Pulse; Sulfonamides; Thiazines; Thiophenes; Timolol; Young Adult | 2011 |
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study.
Topics: Aged; Antihypertensive Agents; Diagnostic Techniques, Ophthalmological; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiazines; Thiophenes; Timolol | 2011 |
Efficacy of single glaucoma drug in combined timolol XE, latanoprost and brinzolamide therapy: a discontinuation study.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2012 |
Effects of brinzolamide on ocular haemodynamics in healthy volunteers.
Topics: Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Double-Blind Method; Eye; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Prospective Studies; Retinal Vessels; Sulfonamides; Thiazines; Ultrasonography, Doppler, Color; Vascular Resistance; Visual Field Tests; Visual Fields | 2004 |
Ocular hypotensive effect and safety of brinzolamide ophthalmic solution in open angle glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Consumer Product Safety; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Timolol | 2004 |
Comparing the effects of travoprost and brinzolamide on intraocular pressure after phacoemulsification.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Care; Prospective Studies; Sulfonamides; Thiazines; Travoprost | 2005 |
Effect of topical brinzolamide 1% and brimonidine 0.2% on intraocular pressure after phacoemulsification.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Tonometry, Ocular | 2004 |
Concomitant administration of travoprost and brinzolamide versus fixed latanoprost/timolol combined therapy: three-month comparison of efficacy and safety.
Topics: Cloprostenol; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Travoprost | 2004 |
Medical control of intraocular pressure after phacoemulsification.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Time Factors; Tonometry, Ocular | 2005 |
The efficacy and safety of topical brinzolamide and dorzolamide when added to the combination therapy of latanoprost and a beta-blocker in patients with glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Instillation, Drug; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Treatment Outcome | 2005 |
Intraocular pressure lowering effect of brinzolamide 1.0% as adjunctive therapy to latanoprost 0.005% in patients with open angle glaucoma or ocular hypertension: an uncontrolled, open-label study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Treatment Outcome | 2005 |
The efficacy and ocular discomfort of substituting brinzolamide for dorzolamide in combination therapy with latanoprost, timolol, and dorzolamide.
Topics: Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision, Ocular | 2005 |
A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Travoprost | 2006 |
[Combined therapy in glaucoma treatment: travoprost 0.004% and brinzolamid].
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiazines; Timolol; Travoprost | 2006 |
Brinzolamide 1% versus apraclonidine 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Prospective Studies; Sulfonamides; Thiazines; Tonometry, Ocular | 2006 |
Ocular hypotensive efficacy and safety of brinzolamide ophthalmic suspension 1% added to travoprost ophthalmic solution 0.004% therapy in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiazines; Travoprost | 2006 |
Influence of ocular hypotensive eyedrops on intraocular pressure fluctuation with postural change in eyes with normal-tension glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Posture; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Visual Field Tests | 2007 |
Comparison of the ocular hypotensive efficacy of adjunctive brimonidine 0.15% or brinzolamide 1% in combination with travoprost 0.004%.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cloprostenol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiazines; Travoprost; Treatment Outcome | 2007 |
Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat.
Topics: Acetazolamide; Acetylcholine; Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2007 |
[Additive therapy with carboanhydrase inhibitors for open angle glaucoma previously treated with timolol 0.5% drops].
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Thiophenes; Timolol | 2007 |
Efficacy of brinzolamide and levobetaxolol in pediatric glaucomas: a randomized clinical trial.
Topics: Adrenergic beta-Antagonists; Betaxolol; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Treatment Outcome | 2008 |
A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Oxygen; Pilot Projects; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes; Visual Acuity | 2008 |
Brimonidine purite 0.1% versus brinzolamide 1% as adjunctive therapy to latanoprost in patients with glaucoma or ocular hypertension.
Topics: Adult; Aged; Analysis of Variance; Brimonidine Tartrate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Maximum Tolerated Dose; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Organization and Administration; Probability; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Severity of Illness Index; Single-Blind Method; Sulfonamides; Thiazines; Tonometry, Ocular; Treatment Outcome | 2008 |
Intraocular pressure reduction with travoprost/timolol fixed combination, with and without adjunctive brinzolamide, in glaucoma.
Topics: Aged; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Timolol; Travoprost | 2008 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes | 1999 |
The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Adjunctive therapy with brinzolamide 1% ophthalmic suspension (Azopt) in patients with open-angle glaucoma or ocular hypertension maintained on timolol therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Timolol; Treatment Outcome | 2000 |
Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Brinzolamide Comfort Study Group.
Topics: Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Dose-response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt). Brinzolamide Dose-Response Study Group.
Topics: Adolescent; Adult; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Suspensions; Thiazines; Treatment Outcome | 2000 |
The long-term safety and efficacy of brinzolamide 1.0% (azopt) in patients with primary open-angle glaucoma or ocular hypertension. The Brinzolamide Long-Term Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Timolol | 2000 |
Comparison of the efficacy of betaxolol-brinzolamide and timolol-dorzolamide as suppressors of aqueous humor flow in human subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Patients' acceptance of a switch from dorzolamide to brinzolamide for the treatment of glaucoma in a clinical practice setting.
Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Patient Satisfaction; Prospective Studies; Sulfonamides; Thiazines; Thiophenes | 2000 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
57 other study(ies) available for brinzolamide and Intraocular Pressure
| Article | Year |
|---|---|
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?
Topics: Administration, Topical; Animals; Aqueous Humor; Benzene Derivatives; Carbonic Anhydrase Inhibitors; Cattle; Eye; Humans; Intraocular Pressure; Isoenzymes; Male; Ophthalmic Solutions; Pyridines; Rabbits; Solubility; Structure-Activity Relationship; Sulfonamides; Thiadiazoles; Tissue Distribution | 1999 |
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane Permeability; Cornea; Delayed-Action Preparations; Dipeptides; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Models, Molecular; Rabbits; Solubility; Sulfonamides; Time Factors | 1999 |
2H-Thieno[3,2-e]- and [2,3-e]-1,2-thiazine-6-sulfonamide 1,1-dioxides as ocular hypotensive agents: synthesis, carbonic anhydrase inhibition and evaluation in the rabbit.
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Magnetic Resonance Spectroscopy; Rabbits; Sulfonamides | 2000 |
Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Rabbits; Sulfonamides | 2001 |
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.
Topics: Administration, Topical; Animals; Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Esters; Glaucoma; Humans; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes | 2003 |
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Hypertension; Intraocular Pressure; Male; Monosaccharides; Rabbits; Sulfanilamides | 2004 |
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Drug Design; Glaucoma; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides | 2005 |
Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure.
Topics: Animals; Carbonic Anhydrase Inhibitors; Drug Design; Glaucoma; Intraocular Pressure; Male; Nitric Oxide Donors; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2015 |
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Crystallography, X-Ray; Drug Design; Glaucoma; Humans; Intraocular Pressure; Male; Molecular Structure; Protein Binding; Rabbits; Structure-Activity Relationship; Sulfonamides | 2020 |
Intraluminal deposits: A rare cause of glaucoma drainage implant total obstruction.
Topics: Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Timolol | 2023 |
Intraocular pressure-lowering effects and safety of brimonidine/brinzolamide fixed combination after switching from other medications.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiazines | 2022 |
[Efficacy and safety of a fixed combination drug Brinzolol Duo in the treatment of patients with primary open-angle glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Timolol; Treatment Outcome | 2022 |
Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination in prostaglandin analog-treated Japanese glaucoma patients.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; East Asian People; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Prostaglandins, Synthetic; Timolol | 2023 |
The effect of a brinzolamide/brimonidine fixed combination on optic nerve head blood flow in rabbits.
Topics: Animals; Blood Flow Velocity; Brimonidine Tartrate; Cross-Over Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Optic Disk; Rabbits; Regional Blood Flow | 2023 |
Real-life experience of using brinzolamide/brimonidine fixed drop combination in a tertiary glaucoma centre.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Tertiary Care Centers; Thiazines; Tonometry, Ocular | 2020 |
Brinzolamide loaded chitosan-pectin mucoadhesive nanocapsules for management of glaucoma: Formulation, characterization and pharmacodynamic study.
Topics: Animals; Biological Availability; Carbonic Anhydrase Inhibitors; Chitosan; Cornea; Drug Carriers; Drug Delivery Systems; Glaucoma; Intraocular Pressure; Nanocapsules; Nanoparticles; Ophthalmic Solutions; Particle Size; Pectins; Polyelectrolytes; Rabbits; Sulfonamides; Thiazines | 2020 |
Prescribing Trends of Topical Glaucoma Medications in Australia From 2001 to 2017.
Topics: Administration, Ophthalmic; Adrenergic Agonists; Antihypertensive Agents; Australia; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Glaucoma, Open-Angle; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Ophthalmic Solutions; Practice Patterns, Physicians'; Sulfonamides; Thiazines; Timolol | 2020 |
Design, optimisation and evaluation of in situ gelling nanoemulsion formulations of brinzolamide.
Topics: Administration, Ophthalmic; Animals; Castor Oil; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Emulsions; Glaucoma; Humans; Intraocular Pressure; Nanoparticles; Polysaccharides, Bacterial; Polysorbates; Rabbits; Sulfonamides; Thiazines | 2020 |
Brinzolamide Dimethyl Sulfoxide In Situ Gelling Ophthalmic Solution: Formulation Optimisation and In Vitro and In Vivo Evaluation.
Topics: Animals; Castor Oil; Dimethyl Sulfoxide; Drug Compounding; Drug Liberation; Excipients; Gels; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Polysaccharides, Bacterial; Polysorbates; Rabbits; Sulfonamides; Thiazines | 2020 |
Co-delivery of brinzolamide and miRNA-124 by biodegradable nanoparticles as a strategy for glaucoma therapy.
Topics: Animals; Carbonic Anhydrase Inhibitors; Decanoic Acids; Delayed-Action Preparations; Dicarboxylic Acids; Drug Delivery Systems; Drug Liberation; Gene Transfer Techniques; Glaucoma; Intraocular Pressure; Mice; Mice, Inbred C57BL; MicroRNAs; Nanoparticles; Neuroprotective Agents; Polyethylene Glycols; Rabbits; Sulfonamides; Thiazines | 2020 |
Pure Glaucoma Drugs Are Toxic to Immortalized Human Corneal Epithelial Cells, but They Do Not Destabilize Lipid Membranes.
Topics: Antihypertensive Agents; Apoptosis; Brimonidine Tartrate; Cell Line; Cell Membrane; Cell Survival; Electrophoresis, Capillary; Epithelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Liposomes; Membrane Lipids; Ocular Hypertension; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2017 |
The Effect of a Decrease in Intraocular Pressure on Optic Nerve Function in Patients with Optic Nerve Drusen.
Topics: Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Electroretinography; Evoked Potentials, Visual; Female; Humans; Intraocular Pressure; Male; Middle Aged; Nerve Fibers; Optic Disk Drusen; Optic Nerve; Retinal Ganglion Cells; Sulfonamides; Thiazines; Tomography, Optical Coherence; Tonometry, Ocular; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult | 2019 |
Changes in Ocular Hemodynamics after Carotid Artery Angioplasty and Stenting (CAAS) in Patients with Different Severity of Ocular Ischemic Syndrome.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carotid Artery, Internal; Carotid Stenosis; Drug Therapy, Combination; Eye; Female; Humans; Intraocular Pressure; Iris; Ischemia; Laser Coagulation; Male; Neovascularization, Pathologic; Ophthalmic Artery; Prospective Studies; Retinal Vessels; Stents; Sulfonamides; Thiazines; Timolol; Ultrasonography, Doppler, Color; Visual Acuity | 2018 |
The Efficacy and Safety of the Fixed Combination of Brinzolamide 1% and Brimonidine 0.2% in Normal Tension Glaucoma: An 18-Month Retrospective Study.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiazines | 2018 |
A novel ocular delivery of brinzolamide based on gellan gum: in vitro and in vivo evaluation.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Drug Liberation; Gels; Intraocular Pressure; Ophthalmic Solutions; Polysaccharides, Bacterial; Rabbits; Rheology; Sulfonamides; Thiazines | 2018 |
Brinzolamide-brimonidine fixed combination to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Posterior Capsulotomy; Postoperative Complications; Sulfonamides; Thiazines | 2018 |
TPGS modified nanoliposomes as an effective ocular delivery system to treat glaucoma.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cell Line; Chemistry, Pharmaceutical; Cornea; Delayed-Action Preparations; Drug Delivery Systems; Glaucoma; Intraocular Pressure; Liposomes; Male; Mice; Nanoparticles; Particle Size; Permeability; Rabbits; Sulfonamides; Thiazines; Vitamin E | 2018 |
Comparison of different combinations of maximum medical therapy for lowering intraocular pressure in primary open angle glaucoma: 12-month retrospective consecutive case series.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiazines; Time Factors; Timolol; Treatment Outcome | 2019 |
A New Standard for 24-Hour Intraocular Pressure Studies.
Topics: Brimonidine Tartrate; Intraocular Pressure; Sulfonamides; Thiazines; Tonometry, Ocular | 2019 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Switching prostaglandin analogues and 24-hour IOP fluctuations.
Topics: Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Monitoring, Physiologic; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Time Factors | 2013 |
Ophthalmic delivery of brinzolamide by liquid crystalline nanoparticles: in vitro and in vivo evaluation.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Cornea; Crystallization; In Vitro Techniques; Intraocular Pressure; Microscopy, Electron, Transmission; Nanoparticles; Rabbits; Scattering, Small Angle; Sulfonamides; Thiazines | 2013 |
Development of inclusion complex of brinzolamide with hydroxypropyl-β-cyclodextrin.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cornea; Hydrogen-Ion Concentration; Intraocular Pressure; Permeability; Rabbits; Solubility; Solvents; Sulfonamides; Thiazines; Volatilization | 2013 |
Brinzolamide nanocrystal formulations for ophthalmic delivery: reduction of elevated intraocular pressure in vivo.
Topics: Administration, Ophthalmic; Animals; Calorimetry, Differential Scanning; Carbonic Anhydrase Inhibitors; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Disease Models, Animal; Epithelium, Corneal; Excipients; Glaucoma; Humans; Hypromellose Derivatives; Intraocular Pressure; Male; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Particle Size; Polysorbates; Rats, Wistar; Solubility; Sulfonamides; Surface Properties; Technology, Pharmaceutical; Thiazines; Time Factors | 2014 |
Managing advanced unilateral pseudoexfoliative glaucoma.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Hypertrichosis; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Pigmentation Disorders; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Trabeculectomy | 2014 |
Reversible Conjunctival Pigmentation Associated With Prostaglandin Use.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Conjunctival Diseases; Drug Substitution; Humans; Hyperpigmentation; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiazines; Tonometry, Ocular; Travoprost | 2016 |
The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed-angle glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2015 |
In vitro and in vivo corneal effects of latanoprost combined with brimonidine, timolol, dorzolamide, or brinzolamide.
Topics: Animals; Brimonidine Tartrate; Cell Survival; Electric Impedance; Epithelium, Corneal; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol | 2016 |
PLGA Nanoparticles as Subconjunctival Injection for Management of Glaucoma.
Topics: Animals; Conjunctiva; Drug Carriers; Drug Delivery Systems; Drug Liberation; Glaucoma; Intraocular Pressure; Lactic Acid; Male; Nanoparticles; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Sulfonamides; Thiazines | 2017 |
Clinical case of influenza A with outer retinal maculopathy.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Eye Infections, Viral; Fluorescein Angiography; Glucocorticoids; Humans; Influenza A virus; Influenza, Human; Intraocular Pressure; Male; Middle Aged; Nasopharynx; Retinal Diseases; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence; Visual Acuity | 2017 |
Brinzolamide/timolol: in open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazines; Timolol | 2009 |
Knockdown of NBCe1 in vivo compromises the corneal endothelial pump.
Topics: Animals; Bicarbonates; Biological Transport, Active; Blotting, Western; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Endothelium, Corneal; Gene Knockdown Techniques; Gene Silencing; Genetic Vectors; Green Fluorescent Proteins; Immunodeficiency Virus, Feline; Intraocular Pressure; Membrane Transport Proteins; Microscopy, Fluorescence; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sodium-Bicarbonate Symporters; Sulfonamides; Thiazines; Transfection | 2010 |
Changes of the Retina and Intrinsic Survival Signals in a Rat Model of Glaucoma following Brinzolamide and Travoprost Treatments.
Topics: Administration, Topical; Animals; Antihypertensive Agents; bcl-X Protein; Blotting, Western; Carbonic Anhydrase Inhibitors; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Signal Transduction; Sulfonamides; Thiazines; Travoprost | 2011 |
The intraocular pressure reducing effect of brinzolamide as adjunctive therapy to latanoprost.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiazines | 2011 |
Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost | 2011 |
Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Feasibility Studies; Intraocular Pressure; Latanoprost; Mice; Mice, Inbred C57BL; Microspheres; Muscarinic Agonists; Ocular Hypertension; Optic Nerve; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Retinal Ganglion Cells; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence | 2012 |
[Therapy of normal tension glaucoma: effect of brinzolamide on ocular haemodynamics].
Topics: Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Eye; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Pulsatile Flow; Reference Values; Regional Blood Flow; Sulfonamides; Thiazines; Ultrasonography, Doppler, Color; Vascular Resistance | 2003 |
Effects of brinzolamide on aqueous humor dynamics in monkeys and rabbits.
Topics: Animals; Aqueous Humor; Female; Intraocular Pressure; Macaca fascicularis; Ocular Hypertension; Rabbits; Sulfonamides; Thiazines | 2003 |
Effects of topical administration of 1% brinzolamide on normal cat eyes.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cats; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiazines | 2003 |
Topical brinzolamide and metabolic acidosis.
Topics: Acidosis; Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiazines | 2006 |
[Therapeutic difficulties in neovascular glaucoma].
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Cryosurgery; Drug Therapy, Combination; Eye Enucleation; Female; Glaucoma, Neovascular; Humans; Intraocular Pressure; Laser Coagulation; Light Coagulation; Male; Middle Aged; Ophthalmic Solutions; Prognosis; Retrospective Studies; Sulfonamides; Thiazines; Trabeculectomy; Treatment Failure | 2006 |
[Clinical investigation: the intraocular pressure-lowering efficacy and safety of brinzolamide combined with betaxolol].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Betaxolol; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiazines; Tonometry, Ocular | 2005 |
Advanced juvenile open-angle glaucoma in an 8-year-old Haitian girl.
Topics: Carbonic Anhydrase Inhibitors; Child; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Optic Nerve Diseases; Sulfonamides; Thiazines; Vision Disorders | 2008 |
Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glaucoma; Horse Diseases; Horses; Intraocular Pressure; Male; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiazines | 2008 |
Brinzolamide--a new topical carbonic anhydrase inhibitor for glaucoma.
Topics: Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiazines | 1998 |
Increased optic nerve head blood flow after 1 week of twice daily topical brinzolamide treatment in Dutch-belted rabbits.
Topics: Animals; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Hemodynamics; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Ophthalmic Solutions; Optic Disk; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2000 |
[Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Rabbits; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol | 2001 |