Compounds > brimonidine tartrate
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brimonidine tartrate and Ischemia

brimonidine tartrate has been researched along with Ischemia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, PC; Ichhpujani, P; Narang, S; Sood, S1
Chai, S; Ellisman, MH; Ju, WK; Kim, KY; Lee, D; Lindsey, JD; Noh, YH; Weinreb, RN1
Avilés-Trigueros, M; García-Avilés, A; Lafuente, MP; Mayor-Torroglosa, S; Miralles de Imperial, J; Rodríguez, ME; Vidal-Sanz, M; Villegas-Pérez, MP1
Baidya, KP; Bhaduri, G; Bhattacharya, B; Chatterjee, PR; Mondal, LK1
Avilés-Trigueros, M; de Imperial, JM; De la Villa, P; García-Avilés, A; López-Herrera, MP; Mayor-Torroglosa, S; Rodríguez, ME; Vidal-Sanz, M; Villegas-Pérez, MP1
Coats, P; Hillier, C; Jarajapu, YP; MacDonald, A; McGrath, JC1
Donello, JE; Gil, DW; Padillo, EU; Webster, ML; Wheeler, LA1
Aguilera, ME; Lafuente, MP; Mayor, S; Miralles de Imperial, J; Vidal-Sanz, M; Villegas-Pérez, MP1

Trials

2 trial(s) available for brimonidine tartrate and Ischemia

ArticleYear
Role of brimonidine in the treatment of clinically significant macular edema with ischemic changes in diabetic maculopathy.
    International ophthalmology, 2014, Volume: 34, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Brimonidine Tartrate; Diabetic Retinopathy; Female; Humans; Ischemia; Macular Edema; Male; Middle Aged; Prospective Studies; Quinoxalines; Retinal Vessels; Visual Acuity

2014
The efficacy of topical administration of brimonidine to reduce ischaemia in the very early stage of diabetic retinopathy in good controlled type-2 diabetes mellitus.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Aneurysm; Antihypertensive Agents; Blood Glucose; Brimonidine Tartrate; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Ischemia; Middle Aged; Prospective Studies; Quinoxalines; Time Factors; Treatment Outcome; Vision, Ocular

2004

Other Studies

6 other study(ies) available for brimonidine tartrate and Ischemia

ArticleYear
Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; bcl-2-Associated X Protein; bcl-Associated Death Protein; Brimonidine Tartrate; DNA-Binding Proteins; Glutamic Acid; Ischemia; Mitochondrial Proteins; Oxidative Phosphorylation; Oxidative Stress; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Diseases; Retinal Ganglion Cells; Superoxide Dismutase; Transcription Factors

2012
Transient ischemia of the retina results in massive degeneration of the retinotectal projection: long-term neuroprotection with brimonidine.
    Experimental neurology, 2003, Volume: 184, Issue:2

    Topics: Afferent Pathways; Animals; Axonal Transport; Brain Stem; Brimonidine Tartrate; Cholera Toxin; Eye; Female; Functional Laterality; Image Processing, Computer-Assisted; Immunohistochemistry; Ischemia; Mesencephalon; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Staining and Labeling

2003
Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:10

    Topics: Animals; Brimonidine Tartrate; Electroretinography; Female; Ischemia; Ligation; Nerve Degeneration; Neuroprotective Agents; Ophthalmic Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Retinal Ganglion Cells; Retinal Vessels; Superior Colliculi; Time Factors; Visual Pathways

2005
Increased alpha(1)- and alpha(2)-adrenoceptor-mediated contractile responses of human skeletal muscle resistance arteries in chronic limb ischemia.
    Cardiovascular research, 2001, Volume: 49, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Arteries; Brimonidine Tartrate; Chronic Disease; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Ischemia; Leg; Male; Middle Aged; Muscle, Skeletal; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Vasoconstrictor Agents

2001
alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Brimonidine Tartrate; Chromatography, Liquid; Electroretinography; Extracellular Space; Glutamic Acid; Ischemia; Male; Mass Spectrometry; Quinoxalines; Rats; Rats, Inbred BN; Retina; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body; Yohimbine

2001
Neuroprotective effects of brimonidine against transient ischemia-induced retinal ganglion cell death: a dose response in vivo study.
    Experimental eye research, 2002, Volume: 74, Issue:2

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Death; Dose-Response Relationship, Drug; Ischemia; Microscopy, Fluorescence; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Ganglion Cells; Time Factors

2002