Page last updated: 2024-10-23

bretylium and Reflex Sympathetic Dystrophy

bretylium has been researched along with Reflex Sympathetic Dystrophy in 6 studies

bretylium: RN given refers to parent cpd
bretylium : A quaternary ammonium cation having 2-bromobenzyl, ethyl and two methyl groups attached to the nitrogen. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.

Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)

Research Excerpts

ExcerptRelevanceReference
"Patients with reflex sympathetic dystrophy, who received transient pain relief from stellate ganglion blocks or lumbar sympathetic blocks and had abnormal isolated cold stress tests, were enrolled in a study to determine the efficacy of intravenous regional bretylium."9.07Intravenous regional bretylium and lidocaine for treatment of reflex sympathetic dystrophy: a randomized, double-blind study. ( Fleming, LL; Hord, AH; Rogers, HG; Rooks, MD; Stephens, BO, 1992)
"Patients with reflex sympathetic dystrophy, who received transient pain relief from stellate ganglion blocks or lumbar sympathetic blocks and had abnormal isolated cold stress tests, were enrolled in a study to determine the efficacy of intravenous regional bretylium."5.07Intravenous regional bretylium and lidocaine for treatment of reflex sympathetic dystrophy: a randomized, double-blind study. ( Fleming, LL; Hord, AH; Rogers, HG; Rooks, MD; Stephens, BO, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Criscuolo, C1
Nepper, G1
Buchalter, S1
Dzwierzynski, WW1
Sanger, JR1
Hord, AH1
Rooks, MD1
Stephens, BO1
Rogers, HG1
Fleming, LL1
Manchikanti, L1
Hanowell, LH1
Kanefield, JK1
Soriano, SG1
Ford, SR1
Forrest, WH1
Eltherington, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Agreement Between Venous and Arterial Blood Gas Measurements in the Intensive Care Unit[NCT00569634]40 participants (Actual)Interventional2008-01-31Completed
Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit[NCT01624519]50 participants (Anticipated)Interventional2012-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for bretylium and Reflex Sympathetic Dystrophy

ArticleYear
Reflex sympathetic dystrophy following arterial blood gas sampling in the intensive care setting.
    Chest, 1995, Volume: 108, Issue:2

    Topics: Autonomic Nerve Block; Blood Gas Analysis; Bretylium Compounds; Critical Care; Female; Humans; Middl

1995
Reflex sympathetic dystrophy following arterial blood gas sampling in the intensive care setting.
    Chest, 1995, Volume: 108, Issue:2

    Topics: Autonomic Nerve Block; Blood Gas Analysis; Bretylium Compounds; Critical Care; Female; Humans; Middl

1995
Reflex sympathetic dystrophy following arterial blood gas sampling in the intensive care setting.
    Chest, 1995, Volume: 108, Issue:2

    Topics: Autonomic Nerve Block; Blood Gas Analysis; Bretylium Compounds; Critical Care; Female; Humans; Middl

1995
Reflex sympathetic dystrophy following arterial blood gas sampling in the intensive care setting.
    Chest, 1995, Volume: 108, Issue:2

    Topics: Autonomic Nerve Block; Blood Gas Analysis; Bretylium Compounds; Critical Care; Female; Humans; Middl

1995
Reflex sympathetic dystrophy.
    Hand clinics, 1994, Volume: 10, Issue:1

    Topics: Autonomic Nerve Block; Bretylium Compounds; Combined Modality Therapy; Humans; Psychotherapy; Reflex

1994

Trials

1 trial available for bretylium and Reflex Sympathetic Dystrophy

ArticleYear
Intravenous regional bretylium and lidocaine for treatment of reflex sympathetic dystrophy: a randomized, double-blind study.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:6

    Topics: Autonomic Nerve Block; Bretylium Compounds; Double-Blind Method; Extremities; Humans; Infusions, Int

1992

Other Studies

3 other studies available for bretylium and Reflex Sympathetic Dystrophy

ArticleYear
Role of intravenous regional bretylium in reflex sympathetic dystrophy.
    Anesthesiology, 1990, Volume: 73, Issue:3

    Topics: Adult; Aged; Autonomic Nerve Block; Bretylium Compounds; Female; Humans; Male; Middle Aged; Reflex S

1990
A recommendation for reduced lidocaine dosage during intravenous regional bretylium treatment of reflex sympathetic dystrophy.
    Anesthesiology, 1989, Volume: 71, Issue:5

    Topics: Adult; Bretylium Compounds; Drug Administration Schedule; Female; Humans; Injections, Intravenous; L

1989
The treatment of reflex sympathetic dystrophy with intravenous regional bretylium.
    Anesthesiology, 1988, Volume: 68, Issue:1

    Topics: Autonomic Nerve Block; Bretylium Compounds; Female; Humans; Middle Aged; Reflex Sympathetic Dystroph

1988