bretylium has been researched along with Lupus Nephritis in 2 studies
bretylium: RN given refers to parent cpd
bretylium : A quaternary ammonium cation having 2-bromobenzyl, ethyl and two methyl groups attached to the nitrogen. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.
Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The bretylium-treated animals also exhibited an improved renal pathology index but they did not differ from the controls with respect to proteinuria and hematuria." | 1.27 | Beneficial effect of captopril on systemic lupus erythematosus-like disease in MRL lpr/lpr mice. ( Herlitz, H; Svalander, C; Tarkowski, A; Volkmann, R; Westberg, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herlitz, H | 2 |
| Svalander, C | 2 |
| Tarkowski, A | 2 |
| Westberg, G | 2 |
| Volkmann, R | 1 |
2 other studies available for bretylium and Lupus Nephritis
| Article | Year |
|---|---|
Influence of antihypertensive treatment on renal and extrarenal lupus manifestations in MRL/l mice.
Topics: Animals; Blood Pressure; Bretylium Compounds; Captopril; Enalapril; Female; Hypertension; Lupus Neph | 1988 |
Beneficial effect of captopril on systemic lupus erythematosus-like disease in MRL lpr/lpr mice.
Topics: Animals; Blood Pressure; Bretylium Compounds; Captopril; Cyclophosphamide; Dermatitis; Female; Lupus | 1988 |