brequinar has been researched along with Melanoma in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ab, A; Dorasamy, MS; Nellore, K; Wong, PF | 1 |
| Cleaveland, ES; Cooney, DA; Ford, H; Kelley, JA; Paull, K; Zaharevitz, DW | 1 |
| Carlson, R; Dallaire, B; Grillo-Lopez, A; Gyves, J; Lynch, W; Moore, M; Natale, R; Wheeler, R | 1 |
1 trial(s) available for brequinar and Melanoma
| Article | Year |
|---|---|
Multicenter phase II trial of brequinar sodium in patients with advanced melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Biphenyl Compounds; Female; Humans; Male; Melanoma; Middle Aged | 1992 |
2 other study(ies) available for brequinar and Melanoma
| Article | Year |
|---|---|
Synergistic inhibition of melanoma xenografts by Brequinar sodium and Doxorubicin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Humans; Melanoma; Mice; Mice, Nude; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lung Neoplasms; Male; Melanoma; Mitochondria; Orotic Acid; Ovarian Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prostatic Neoplasms; Ribonucleotides; Sodium Bicarbonate; Software; Tumor Cells, Cultured | 1996 |