brequinar has been researched along with Lung Neoplasms in 5 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Beytagh, MC; Bhutkar, A; Colón, CI; Drapkin, BJ; Dyson, NJ; Farago, AF; Hsu, PP; Jacks, T; Lewis, CA; Li, L; Li, Z; Mercer, KL; Muzumdar, MD; Myers, DT; Nabel, CS; Ng, SR; Phat, S; Romero, R; Vander Heiden, MG; Westcott, PMK | 1 |
Dallaire, B; Gyves, J; Maroun, J; Morgan, R; Natale, R; Ruckdeschel, J; Sisk, R | 1 |
Cleaveland, ES; Cooney, DA; Ford, H; Kelley, JA; Paull, K; Zaharevitz, DW | 1 |
Bork, E; Hansen, HH; Vest, S | 1 |
Ardecky, RJ; DeLarco, BM; Dexter, DL; Dusak, BA; Hesson, DP; Narayanan, VL; Paull, KD; Plowman, J; Rao, GV; Tippett, DL | 1 |
1 trial(s) available for brequinar and Lung Neoplasms
Article | Year |
---|---|
Multicenter phase II study of brequinar sodium in patients with advanced lung cancer.
Topics: Aged; Antineoplastic Agents; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1993 |
4 other study(ies) available for brequinar and Lung Neoplasms
Article | Year |
---|---|
Identification of DHODH as a therapeutic target in small cell lung cancer.
Topics: Adenocarcinoma; Animals; Biphenyl Compounds; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; DCMP Deaminase; Dihydroorotate Dehydrogenase; Disease Progression; Enzyme Inhibitors; Humans; Lung Neoplasms; Mice; Molecular Targeted Therapy; Oxidoreductases Acting on CH-CH Group Donors; Pancreatic Neoplasms; Pyrimidines; Small Cell Lung Carcinoma; Survival Analysis; Xenograft Model Antitumor Assays | 2019 |
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lung Neoplasms; Male; Melanoma; Mitochondria; Orotic Acid; Ovarian Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prostatic Neoplasms; Ribonucleotides; Sodium Bicarbonate; Software; Tumor Cells, Cultured | 1996 |
A phase I clinical and pharmacokinetic study of Brequinar sodium, DUP 785 (NSC 368390), using a weekly and a biweekly schedule.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biphenyl Compounds; Drug Administration Schedule; Drug Evaluation; Female; Genital Neoplasms, Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Platelet Count; Urologic Neoplasms | 1989 |
Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarb oxylic acid sodium salt], against experimental tumors.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Biphenyl Compounds; Colonic Neoplasms; Female; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous | 1985 |