brequinar has been researched along with Leukemia L 1210 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Behrens, DL; Chen, SF; Papp, LM; Perrella, FW | 1 |
| Christopherson, RI; Lyons, SD | 1 |
| Aungst, BJ; Blake, JA; Dusak, BA; Rogers, NJ | 1 |
| Ardecky, RJ; Chen, SF; Dexter, DL; Forbes, M; Hesson, DP; Papp, LM; Rao, GV | 1 |
| Anderson, LW; Cysyk, RL; Strong, JM | 1 |
| Laurensse, E; Peters, GJ; Pinedo, HM; Sharma, SL | 1 |
6 other study(ies) available for brequinar and Leukemia L 1210
| Article | Year |
|---|---|
Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Dehydrogenase; Kinetics; Leukemia L1210; Mice; Naphthoquinones; Orotic Acid; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors | 1992 |
Effects of brequinar and ciprofloxacin on de novo nucleotide biosynthesis in mouse L1210 leukemia.
Topics: Animals; Biphenyl Compounds; Cell Division; Chromatography, High Pressure Liquid; Ciprofloxacin; Dihydroorotate Oxidase; DNA, Neoplasm; Enzyme Induction; Leukemia L1210; Mice; Nucleotides; RNA, Neoplasm; Tumor Cells, Cultured | 1990 |
Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent.
Topics: Animals; Antineoplastic Agents; Aspirin; Biphenyl Compounds; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Ibuprofen; Leukemia L1210; Male; Mice; Protein Binding; Rats; Rats, Inbred Lew; Tissue Distribution | 1990 |
Structure-activity relationship of quinoline carboxylic acids. A new class of inhibitors of dihydroorotate dehydrogenase.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Dehydrogenase; Leukemia L1210; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Structure-Activity Relationship | 1990 |
Cellular pharmacology of DUP-785, a new anticancer agent.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Division; Cells, Cultured; Chromatography, Gas; Dihydroorotate Oxidase; Dose-Response Relationship, Drug; In Vitro Techniques; Leukemia L1210; Mass Spectrometry; Mice; Time Factors; Uridine | 1989 |
Inhibition of pyrimidine de novo synthesis by DUP-785 (NSC 368390).
Topics: Amides; Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Oxidase; Leukemia L1210; Orotic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Tumor Cells, Cultured | 1987 |